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MGCSREDVLGAFDALDTVVESILALDYDALSAAERVGLDARLERNLRRLPVAEQALIASVIAETEPARLG EGSWKKVLITALRVSGAEAGRRLRRAKALGPRRGLTGTPLPPLWESTAAAQAQGLLGEEHVAIIAKFHKD LPAWVDVDTRAHADRQLARKGAGLGPEELDEAAGRLMMMIDQDGPEPCDKERARKRGVRISKQHSDGTAT ISGTLTPEALAVWQAIFAKEAAPGANLPESEHTEDSTSGGTPRDTETSDHADASGDGVAPSSTAGHGNTS GDDGGDAPAEDHDPQPERCGSDTRTQAQRNHDAFLAVGRRLLESGELGTHNGLPVTVIVSTTLQELEKGA GVAVTGGGSLLPMPDLIRLAARAHHYLYVYDQHSGQSLYLGRAKRLANAAQRIVLHARDRGCTRPGCTAP GYWCQAHHASADFVNGGLTNIDDLTLACPCDHRMLDNTGWRTRKNGKNQTEWLPPPDLDTGQHRVNGHHH PERHLLPEDNLPEDDLPEDDQGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3851 | - | - | 100% (513) | hypothetical protein Mvan_3851 |
| M. vanbaalenii PYR-1 | Mvan_4451 | - | 0.0 | 97.49% (518) | hypothetical protein Mvan_4451 |
| M. vanbaalenii PYR-1 | Mvan_3050 | - | 0.0 | 85.19% (513) | hypothetical protein Mvan_3050 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1179c | - | 1e-101 | 43.26% (497) | hypothetical protein Mb1179c |
| M. gilvum PYR-GCK | Mflv_4014 | - | 1e-166 | 59.68% (506) | hypothetical protein Mflv_4014 |
| M. tuberculosis H37Rv | Rv1128c | - | 1e-101 | 41.43% (502) | hypothetical protein Rv1128c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 1e-100 | 42.77% (484) | hypothetical protein MAB_0394c |
| M. marinum M | MMAR_3121 | - | 1e-110 | 44.53% (512) | hypothetical protein MMAR_3121 |
| M. avium 104 | MAV_2999 | - | 1e-111 | 43.92% (510) | hypothetical protein MAV_2999 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 1e-100 | 41.31% (489) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 6e-71 | 36.40% (522) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-109 | 44.14% (512) | hypothetical protein MUL_2371 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3851|M.vanbaalenii_PYR-1 --------------------------MGCSREDV---LGAFDALDTVVES
Mflv_4014|M.gilvum_PYR-GCK -----------------------MAGLSVGRTSVRCMDGVAEAVGVIGEQ
MSMEG_6573|M.smegmatis_MC2_155 --------------------------MDDG------VQDAVAALDAALNT
MMAR_3121|M.marinum_M ------------------------MHSNGCSD-RESVVATLDRLDRAVDA
MUL_2371|M.ulcerans_Agy99 ------------------------MHSNGCSD-RESVVATLDRLDRAVDA
Rv1128c|M.tuberculosis_H37Rv ----------------------------MCST-REEITEAFASLATALSR
MAV_2999|M.avium_104 -------------------------MRGMSSD-REAVSAAFDAIDAALDD
Mb1179c|M.bovis_AF2122/97 MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHASLSR
MAB_0394c|M.abscessus_ATCC_199 -------------------------------------MSPIDDLLTTATA
TH_3287|M.thermoresistible__bu ----------------------MGQQFVTAGAARARVGELLAAVDAAYAE
Mvan_3851|M.vanbaalenii_PYR-1 --ILALDYDALSAAERVGLDARLERNLRRLPVAEQALIASVIAETEPARL
Mflv_4014|M.gilvum_PYR-GCK LAVLAKAAEDLSHRELIGLLSELTTVLRSAPAVEHAVLARLLDETEPHHL
MSMEG_6573|M.smegmatis_MC2_155 --LLTLPHSALTDAELLTICAGLQDARNRIPAVEHRAIAALSQQTTPAAI
MMAR_3121|M.marinum_M --LVEVSFEALTTPERLRVLERLEVVARRLPVAQYALLNQLDEQAGEAEL
MUL_2371|M.ulcerans_Agy99 --LVEVSFEALTTPERLRVLERLEVVARRLPAAQYALVNQLDEQPGEAEL
Rv1128c|M.tuberculosis_H37Rv --VLGLTFDALTTPERLALLEHCETARRQLPSVEHTLINQIGEQSTEEEL
MAV_2999|M.avium_104 --LLDCDYAALATREKLALLNRCERLRRRLPAIEHPLINALARDATPAEL
Mb1179c|M.bovis_AF2122/97 --VLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEEL
MAB_0394c|M.abscessus_ATCC_199 --VVESSFDELNNPELLSALRQLEIAQRKITAASHTLTARLVQRGSPVAL
TH_3287|M.thermoresistible__bu --MRALCLDEVGTGFRLELAERLETQCRINRGLMYRVFAQLADPPDEPAM
: : : . : :
Mvan_3851|M.vanbaalenii_PYR-1 GEGSWKKVLITALRVSGAEAGRRLRRAKALGPRRGLTGTPLPPLWESTAA
Mflv_4014|M.gilvum_PYR-GCK GEASWKKVLTTSLRMSSAEAGRRLQRAKNLGPRRAMTGEPLAPVWESTAA
MSMEG_6573|M.smegmatis_MC2_155 GAKSWPLVLATRLGISSKEARRRCTDAAELGPRVSMTGEALAPKREHIAA
MMAR_3121|M.marinum_M GGR-LAAVVASRLRITRSEAGRRVAEAADVGPRRALSGQPVGPVLTATAA
MUL_2371|M.ulcerans_Agy99 GGR-LAAVVASRLRITRSEAGRRVAEAAEVGPRRALSGQPVGPVLTATAA
Rv1128c|M.tuberculosis_H37Rv GGK-LGLTLADRLRITRSEAKRRVAEAADLGQRRALTGEPLPPLLTATAK
MAV_2999|M.avium_104 GGR-LSHAIAEATLISRAEAARRVHTAADLGPRVGLTGEPLPPLLAATAA
Mb1179c|M.bovis_AF2122/97 GGT-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAA
MAB_0394c|M.abscessus_ATCC_199 GGTSFAEVLARYLSITTATARRRLADAAHLGPRRALTGEPLRPALPYVAH
TH_3287|M.thermoresistible__bu VPA-VRDRLWARLRITPGEVKRRLRVAALLRPRRRLSGPPLPPVLARVAG
: :: . ** * : * ::* .: . *
Mvan_3851|M.vanbaalenii_PYR-1 AQAQGLLGEEHVAIIAKFHKDLPAWVDVDTRAHADRQLARKGAGLGPEEL
Mflv_4014|M.gilvum_PYR-GCK AQAQGHLGEEHVEIIAKFHKKLPSWVDVDTRAAADAQLAHTGSGLGPEEL
MSMEG_6573|M.smegmatis_MC2_155 AQADGTLTPDHVAELFKFFTKCPDWVTYAEQCRLEEKLVTGAIGADPETV
MMAR_3121|M.marinum_M ALRQGVVGEGHVRVIRDFFRRLPAGVDVGTRDRAEAHLAKLATQFRPDQL
MUL_2371|M.ulcerans_Agy99 ALRQGVVGEGHVRVIRDFFRQLPAGVDVGTRDRAEAHLAKLATQFRPDQL
Rv1128c|M.tuberculosis_H37Rv AQRHGLIGDGHVEVIRAFVHRLPSWVDLKTLEKAERDLAKQATQYRPDQL
MAV_2999|M.avium_104 AQREGSLGLEQVAVIRKFCHQLPGWIDQATRERAEADLANQGTRYRPEQL
Mb1179c|M.bovis_AF2122/97 AQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHL
MAB_0394c|M.abscessus_ATCC_199 ALREGRLGDEHVRIIRRFFDVLPDAVDADTREAAEKQLASMGTEFGPEQL
TH_3287|M.thermoresistible__bu AVESGLLGEEHLRVITTVMAALPSAVSVTDREAVEASLIAEAARSDAGIV
* * : :: : . . : : * . . :
Mvan_3851|M.vanbaalenii_PYR-1 DEAAGRLMMMIDQDGPEPCDKERARKRGVRISKQHSDGTATISGTLTPEA
Mflv_4014|M.gilvum_PYR-GCK AQVADRLLMMIDQDGPEPSEKEKATRFWVKLGTQQRDGGRTISGYVDAET
MSMEG_6573|M.smegmatis_MC2_155 RQAVDHAVFLLDQDGPAPTDNPPTKPFGITFGPQQPDGSYHLRGKVSAEF
MMAR_3121|M.marinum_M ARLAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLTPEA
MUL_2371|M.ulcerans_Agy99 ARLAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLTPEA
Rv1128c|M.tuberculosis_H37Rv AKLAARIMDCLNPDG-DYTDEDRARRRGLTLGKQDVDGMSRLSGYVTPEL
MAV_2999|M.avium_104 AALAGTLADCLNPDG-LYRDEDRARRRSLTLGNQHADGMSELRGLLTPEL
Mb1179c|M.bovis_AF2122/97 HGLATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLTPEL
MAB_0394c|M.abscessus_ATCC_199 RAGADRIAALVNPDG-RFSDIDRARRRGISIGRQGADGMSALSGLLDPET
TH_3287|M.thermoresistible__bu RQVGRRIEEIFNPDG-HYDDQDRARRRGIHLGDQQRDGMSAISGWIDPQL
.. ** : : : :. * ** : * : .:
Mvan_3851|M.vanbaalenii_PYR-1 LAVWQAIFAKEAAPGANLPESEHTEDSTSGGTPRDTETSDHADASGDGVA
Mflv_4014|M.gilvum_PYR-GCK SAYWEAVLAKEAAPGANMAEQ-----------------------------
MSMEG_6573|M.smegmatis_MC2_155 KATFDPIDEKLAAPGMCNPTDQTPCISG----------------------
MMAR_3121|M.marinum_M RAGLEAVWAKLAAPGMCNPEDEAAVVDG----------------------
MUL_2371|M.ulcerans_Agy99 RAGLEAVWAKLAAPGMCNPEDEAAVVDG----------------------
Rv1128c|M.tuberculosis_H37Rv RATIEAVWAKLAAPGMCNPEQKAPCVNG----------------------
MAV_2999|M.avium_104 RATLEAVLAKLAAPGMCNPLDESPCVDG----------------------
Mb1179c|M.bovis_AF2122/97 RATIEAVLAKLAAPGACNPDDQTPLVDD----------------------
MAB_0394c|M.abscessus_ATCC_199 RAYFDAVLSKLAAPGMCDPRDESPMTEG----------------------
TH_3287|M.thermoresistible__bu RAYLEAVTAAVR-PGRHLPHTTTDTTGTTG-------------------T
* :.: ** .
Mvan_3851|M.vanbaalenii_PYR-1 PSSTAGHGNTSGDDGGDAPAEDHDPQPERCGSDTRTQAQRNHDAFLAVGR
Mflv_4014|M.gilvum_PYR-GCK ---------------------------EKAG-DTRTQGQRNHDGLKAVLR
MSMEG_6573|M.smegmatis_MC2_155 -----------------------TPSQQQIDSDQRGAPERRHDAMLTAMR
MMAR_3121|M.marinum_M -----------------------PVSPDAADRDSRSVGQRQHDGFNAALR
MUL_2371|M.ulcerans_Agy99 -----------------------PVSRDAADRDSRSVSQRQHDGFNAALR
Rv1128c|M.tuberculosis_H37Rv -----------------------APSKEQARRDTRSCPQRNHDALNAELR
MAV_2999|M.avium_104 -----------------------TPTEQAIEGDTRSAAQRNHDGLLAGLR
Mb1179c|M.bovis_AF2122/97 -----------------------TPDADAVRRDTRSQAQRNHDAFLAALR
MAB_0394c|M.abscessus_ATCC_199 -----------------------EPDSAAAERDTRTSAQRNHDGLRACLR
TH_3287|M.thermoresistible__bu TETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSAAQRRHDGLTLGLK
* * :*.**.: :
Mvan_3851|M.vanbaalenii_PYR-1 RLLESGELGTHNGLPVTVIVSTTLQELEKGA-----------GVAVTGGG
Mflv_4014|M.gilvum_PYR-GCK RTLESGQLGSHNGLPVTVIVSTTLQELEKGA-----------GVAVTGGG
MSMEG_6573|M.smegmatis_MC2_155 LLLAHKDLGQINGLPATLLVTTTLQELEKAA-----------GVAITAGG
MMAR_3121|M.marinum_M AVLASGELGQHNGLPASIIVSTTLKELEAAA-----------GRGLTGGG
MUL_2371|M.ulcerans_Agy99 AVLASGELGQHNGLPASIIVSTTLKELEAAA-----------GRGLTGGG
Rv1128c|M.tuberculosis_H37Rv SLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------GAGLTGGG
MAV_2999|M.avium_104 ALLASGNLGQHNGLPASIIVTTTLADLETAA-----------GKGLTGGG
Mb1179c|M.bovis_AF2122/97 GLLASGELGQHKGLPVTIVVSTTLKELEAAT-----------GKGVTGGG
MAB_0394c|M.abscessus_ATCC_199 STLASGKLGAHRGLPVTVVVSTTLRELQSAA-----------GRAISGSG
TH_3287|M.thermoresistible__bu IAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADPRVSMPGPARTGGT
: ** .* *.:::* *** :*: .: * . :..
Mvan_3851|M.vanbaalenii_PYR-1 SLLPMPDLIRLAARAHHYLYVYDQHSGQSLYLGRAKRLANAAQRIVLHAR
Mflv_4014|M.gilvum_PYR-GCK SLLPIPELIRLAADAHHYLYVYDGHTGQSLYLGRAKRLANAAQRIVMHAR
MSMEG_6573|M.smegmatis_MC2_155 TKLSIPDLIRLASQALHYLAVYDEHTGIPLYLGRARRTASAGQRLAIWAR
MMAR_3121|M.marinum_M TLLPMSDVIRLARHAHHYLAVF--DRGEAIGLYHAKRLATPGQRIVLYAK
MUL_2371|M.ulcerans_Agy99 TLLPMSDVIRLARHAHHYLAVF--DRGEAIGLYHAKRLATPGQRIVLYAK
Rv1128c|M.tuberculosis_H37Rv TILPISDVIRLARHANHYLAIF--DRGKALALYHTKRLASPAQRIMLYAK
MAV_2999|M.avium_104 TLLPMSDVIRLSRHAHHYLAIF--DKGKALALYHTKRLASPGQRIVLYAK
Mb1179c|M.bovis_AF2122/97 SRVPMSDLIRMASHANHYLALF--DGAKPLALYHTKRLASPAQRIMLYAK
MAB_0394c|M.abscessus_ATCC_199 NLVPIPDLIRMATHAFHYLTIFG-DDGRPLHLGRSKRIATPDQRIVLHAK
TH_3287|M.thermoresistible__bu GVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKRIATADQRLICYAR
:.: ::**:: * *** :: . .: * : :* *.. **: *:
Mvan_3851|M.vanbaalenii_PYR-1 DRGCTRPGCTAPGYWCQAHHASADFVNGGLTNIDDLTLACPCDHRMLDNT
Mflv_4014|M.gilvum_PYR-GCK DRGCTRPGCTVPGYWCQAHHASADWKDDGHTDIDDLTFACGPENRMIENT
MSMEG_6573|M.smegmatis_MC2_155 DRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALALACGCDNRLVGEA
MMAR_3121|M.marinum_M DRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPDHKLLEQG
MUL_2371|M.ulcerans_Agy99 DRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPDHKLLEQG
Rv1128c|M.tuberculosis_H37Rv DSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGHHPLAERG
MAV_2999|M.avium_104 DRGCTAPGCTVPGYYAEVHHCT-DYATCHTTDINDLTFACGPHHRLLQPG
Mb1179c|M.bovis_AF2122/97 DRGCSRPGCDAPAYHSEVHHVT-PWTTTHRTDINDLTLACGPDNRLVEKG
MAB_0394c|M.abscessus_ATCC_199 DRGCSAPGCTVPGYLCQVHHVD-DWRDDGPTDIDNLTFACGPHHRLLQQG
TH_3287|M.thermoresistible__bu DGGCTAPGCGEPGYHAETHHQP-AWEDGGLTDADHLFFACGPHHSGLTEG
* **: *** .* .:.** : *: : * :.* .:
Mvan_3851|M.vanbaalenii_PYR-1 G--WRTRKN-GKNQTEWLPPPDLDTGQHRVNGHHHPERHLLPED------
Mflv_4014|M.gilvum_PYR-GCK G--WTTAKN-SRNQTEWIPPPDLETGQHRVNGYHHPERHLLPHE------
MSMEG_6573|M.smegmatis_MC2_155 PNKWTTRIN-NHGQCEWIPPDLLDRGQHRTNTYHHPETLLADINRDQKTD
MMAR_3121|M.marinum_M ---WRTRKN-AHGDTEWLPPPHLDHGQPRTNTYHHPEKLLR---------
MUL_2371|M.ulcerans_Agy99 ---WRTRKN-AHGDTEWLPPPHLDHGQPRTNSYHHPEKLLR---------
Rv1128c|M.tuberculosis_H37Rv ---WTTRKN-AHGDTEWLPPPHLDHGQPRVNTFHHPEKLL----------
MAV_2999|M.avium_104 A--WTTHKN-ARGETQWLPPPHLDRNQPRTNTFHHPEKLLRGED------
Mb1179c|M.bovis_AF2122/97 ---WKTRKN-AHGDTEWLPPPHLDHGQPRINRYHHPAKILC---------
MAB_0394c|M.abscessus_ATCC_199 ---WTTRKRRSDGITEWIPPPHLDTGQSRTNDHHHPERFIRRF-------
TH_3287|M.thermoresistible__bu R--WQATIT-PTGRLAWTN----DHHPPTVNHAHHPEELLR---------
* : . * : * *** :
Mvan_3851|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4014|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6573|M.smegmatis_MC2_155 GDNREQHHTDTGADTGTVHVNGHGEKPAIPPELLDQGQQRTAPYHQAEVP
MMAR_3121|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
Rv1128c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2999|M.avium_104 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mvan_3851|M.vanbaalenii_PYR-1 -------------------------------NLPEDDLPEDDQGP----
Mflv_4014|M.gilvum_PYR-GCK -------------------------------EGEDSSTSRDCDDP----
MSMEG_6573|M.smegmatis_MC2_155 PVNTRDTRSSTTTRDANRHNGNGDRNSAENRNGPSKNAAGDDDEPR---
MMAR_3121|M.marinum_M ------------------------------------DSADDDDEGHGAA
MUL_2371|M.ulcerans_Agy99 ------------------------------------DSADDDDEGHGAA
Rv1128c|M.tuberculosis_H37Rv --------------------------------------ADDEGDP----
MAV_2999|M.avium_104 ------------------------------------GGEDDDGDDDEAA
Mb1179c|M.bovis_AF2122/97 --------------------------------------EQDDDEPH---
MAB_0394c|M.abscessus_ATCC_199 -------------------------------------------------
TH_3287|M.thermoresistible__bu ------------------------------------AHTDPPEDPG---