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VSETAVFAGRRDGTPVYAYPRRRPQAPVSVLELGPDAPPVRTTHIHEFPVLVYQPATGSVDVVAAGLPVD PGRGGDRTGAVAVFFDPAALGEGARSPWPTWRAHPLLSPFLHGHHDGILRLEVPAARRPFWDAGVAALQA ELTDRRDGYAQAALAHLTVLLIELARLSDDVVGDLRRSNEPLLAQVFDVIERRLGEPLTLRDVARECGLT AGYLTTVVRRRTGRTVGSWIAERRMAEARALLLATELTVGEVGRRVGMTDPGYFTRQFRSCHGESPRTWR ARHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5518 | - | - | 100% (284) | response regulator receiver protein |
| M. vanbaalenii PYR-1 | Mvan_3612 | - | 3e-09 | 28.28% (99) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3008 | - | 5e-08 | 31.31% (99) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2899 | - | 2e-09 | 29.79% (94) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0767c | - | 2e-10 | 31.53% (111) | AraC family transcriptional regulator |
| M. marinum M | MMAR_1063 | - | 5e-97 | 62.77% (282) | transcriptional regulatory protein |
| M. avium 104 | MAV_4063 | - | 4e-05 | 26.92% (156) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_3998 | - | 5e-12 | 43.42% (76) | MmsAB operon regulatory protein |
| M. thermoresistible (build 8) | TH_2340 | - | 8e-07 | 29.63% (108) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_0821 | - | 6e-96 | 62.06% (282) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1063|M.marinum_M ------------------MAQAARLIQHRSGVPIYGY-RTDPDIPRVSVL
MUL_0821|M.ulcerans_Agy99 ------------MDYLWRMAQAARLIQHRSGVPIYGY-RTDPDIPRVSVR
Mvan_5518|M.vanbaalenii_PYR-1 ------------------MSETAVFAGRRDGTPVYAYPRRRPQAP-VSVL
Mflv_2899|M.gilvum_PYR-GCK -------------------MRAKDLVDARYAEPITVDDLAAA--------
MAB_0767c|M.abscessus_ATCC_199 ----------MIHNPDYFADQPKSLSWPTGSPSIDAFSGILSAIGLRGES
MSMEG_3998|M.smegmatis_MC2_155 ---------MDESTAAWIADGFVGQRMLAVPRPVVDHALGAPVTRRLLVT
TH_2340|M.thermoresistible__bu --------------VTVSALSARNLASSAKPPQIDLRRGGRALGG-----
MAV_4063|M.avium_104 MGLTTMTVRDDGAPVGAPAEAARSDYGPVDPVLAVNGERRARPVAVEYKQ
MMAR_1063|M.marinum_M RPGPEDLGDRARHIHDFPALWYVPAAG----------------LVYIAAA
MUL_0821|M.ulcerans_Agy99 RPGPEDLGDRARHIHDFPALWYVPAAG----------------LVYIAAA
Mvan_5518|M.vanbaalenii_PYR-1 ELGPDAPPVRTTHIHEFPVLVYQPATG----------------SVDVVAA
Mflv_2899|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0767c|M.abscessus_ATCC_199 ALRCSAELPFDVSVPANERVLHIAETA----------------GLRVYVD
MSMEG_3998|M.smegmatis_MC2_155 DAGFFPRATRHGRSRSRGATEHVVMVC----------------TAGAGWC
TH_2340|M.thermoresistible__bu --------SYLYEGDKLQTGWHSHDVH----------------QIEYAIG
MAV_4063|M.avium_104 FRGADAQSARRFFATAYDPGWRIAGVTNHCVVSHRRSDTGSMTVDEVAIQ
MMAR_1063|M.marinum_M GQVLEPTQFGSLQGGVAMFF-DPAALGGDGGSPWPSWRTHPLLFPFLHGH
MUL_0821|M.ulcerans_Agy99 GQVLEPTQFGSLQAGVAMFF-DPAALGGDGGSPWPSWRTHPLLFPFLHGH
Mvan_5518|M.vanbaalenii_PYR-1 GLPVDPGRGGDRTGAVAVFF-DPAALGEGARSPWPTWRAHPLLSPFLHGH
Mflv_2899|M.gilvum_PYR-GCK ------------AGLSRAHF-SRMFTRTFGESPRAYLQTR----------
MAB_0767c|M.abscessus_ATCC_199 GNPVCVLAAGDMVLMARGTA-HRLSGAQPHGEPAGTLHWVSGRFTAERKA
MSMEG_3998|M.smegmatis_MC2_155 RTEEGAFDVGVGDAVLLPKG-RAHMYGAAESDPWTLWWMHVTGSDSAELI
TH_2340|M.thermoresistible__bu GVVEVQTRTGHYLLPPQQAA-WLPVGLEHSATMNPDVKTVAVMFDPQLVP
MAV_4063|M.avium_104 GRMTLEIPAGDTVVVIQPRAGALNVAGGPLATPDFPLLVAHGMACVLHCH
MMAR_1063|M.marinum_M SGGILRLEVPAARRSTWDG----------------------------AIA
MUL_0821|M.ulcerans_Agy99 SGGILRLEVPAARRSTWDG----------------------------AIA
Mvan_5518|M.vanbaalenii_PYR-1 HDGILRLEVPAARRPFWDA----------------------------GVA
Mflv_2899|M.gilvum_PYR-GCK -----RLERAASLLRHTDR----------------------------SVA
MAB_0767c|M.abscessus_ATCC_199 ADPLLSVLPPAIIIQAARPGHEWLP---------------------LSLQ
MSMEG_3998|M.smegmatis_MC2_155 AAARVSPVSPVVHLVDPAP----------------------------ATS
TH_2340|M.thermoresistible__bu DAGNRARILAVSPLIREMM-----------------------------IY
MAV_4063|M.avium_104 GARFDVVTIAAEVLQKVAAEWHTALSQQTQFLNWRPRSRAAVRAWHRALD
..
MMAR_1063|M.marinum_M AIEAELTARQQGYGQAVAAHLTLLLIELARLARDV-----VGDLRRSGEP
MUL_0821|M.ulcerans_Agy99 AIEAELTTRQQGYGQAVTAHLTLLLIELARLARDV-----VGDLRRSGEP
Mvan_5518|M.vanbaalenii_PYR-1 ALQAELTDRRDGYAQAALAHLTVLLIELARLSDDV-----VGDLRRSNEP
Mflv_2899|M.gilvum_PYR-GCK DICVMVGLQS------------------------------VGSFTTS---
MAB_0767c|M.abscessus_ATCC_199 LILAEILTPSPGSWVMISRILDLLFIHAVREWSSSSHAE-PGWLTAAMDP
MSMEG_3998|M.smegmatis_MC2_155 LISQVIDMLADASTTAGLIGAAGAAWHALTVIAAT-----GRQRSTGEAD
TH_2340|M.thermoresistible__bu ALRWPIDRPHGDEISDTFFRTLAHLVSEALDHEAP------LSLPTSDHP
MAV_4063|M.avium_104 YAMLTLASPDTARQPLIAAGMAGLLAGALLECYPSNLTEQDPVSDLALPE
: .
MMAR_1063|M.marinum_M LLAEVFEVIDRRHAEPLSLRDVAAEVGMTPGHLTTIVRRRTGRTVQEWII
MUL_0821|M.ulcerans_Agy99 LLAEVFEVIDRRHAEPLSLRDVAAEVGMTPGHLTTIVRRRTGRTVQEWII
Mvan_5518|M.vanbaalenii_PYR-1 LLAQVFDVIERRLGEPLTLRDVARECGLTAGYLTTVVRRRTGRTVGSWIA
Mflv_2899|M.gilvum_PYR-GCK --------FARAYGLPPAAYRASMPSAAVHARIPSCILQRDTRPKADSRV
MAB_0767c|M.abscessus_ATCC_199 RLAPVLTAIHNNLEHPWSIAELAQHARQSRSAFTQRFTELLGQPPAAYIG
MSMEG_3998|M.smegmatis_MC2_155 PVDRALEHLRSTSPRRTDVAALAAIVGLSTSHLNALFRQRTGIGPLEFQQ
TH_2340|M.thermoresistible__bu IVAAAMAYTKEHLQS-VTAEEVSRAVAVSERTLRRQFRQATGISWRTYLL
MAV_4063|M.avium_104 TLKEAVSFIHRHAAEDIGINDVAAAVHLTPRAVQYLFRRQLDTTPTEYMR
: . . .
MMAR_1063|M.marinum_M ERRMAQARELLVATDLA---VGEVARRVGISDPGYFSRLFSRAHGTSPRQ
MUL_0821|M.ulcerans_Agy99 ERRMAQARELLVATDLA---VGEVARRVGISDPGYFSRLFSRAHGTSPRQ
Mvan_5518|M.vanbaalenii_PYR-1 ERRMAEARALLLATELT---VGEVGRRVGMTDPGYFTRQFRSCHGESPRT
Mflv_2899|M.gilvum_PYR-GCK KTAHGEKTGANASP------------------------------------
MAB_0767c|M.abscessus_ATCC_199 ERRLDRAAHLLRSTTDP---VRQIGRAVGYTSDAAFSRAFQRRFGEPPLR
MSMEG_3998|M.smegmatis_MC2_155 QLRMSRARELLDTTTLT---IAAVARAAGFNDPLYFSRQFAKVHGQSPSA
TH_2340|M.thermoresistible__bu HARMLKAMALLAAPDQS---VQETASAVGFDSLSAFTRAFTQFCGETPSA
MAV_4063|M.avium_104 RVRLSRAHQELVAATTASSTVTEIAQRWGFAHTGRFAVLYRQTYGQSPHT
. . :.
MMAR_1063|M.marinum_M WRALPPRH------------
MUL_0821|M.ulcerans_Agy99 WRALPPRH------------
Mvan_5518|M.vanbaalenii_PYR-1 WRARHG--------------
Mflv_2899|M.gilvum_PYR-GCK --------------------
MAB_0767c|M.abscessus_ATCC_199 WRTHHRSG------------
MSMEG_3998|M.smegmatis_MC2_155 YRQRHQN-------------
TH_2340|M.thermoresistible__bu YRHRISTDPHSRPTSADPIG
MAV_4063|M.avium_104 TLRQQTAV------------