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MLPPARYLMRAKDLVDARYSEPITVDDLAAAAGLSRAHFSRMFSKTFGESPRAYLQTRRLERAASLLRHT DRSVADICVMVGLQSVGSFTTSFARTYGMPPAAYRASMPPAAVHARIPSCILQRDTRPKADTRVDKTAHG EKTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3612 | - | - | 100% (144) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3008 | - | 1e-26 | 45.45% (121) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3996 | - | 3e-14 | 33.98% (103) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 2e-08 | 34.57% (81) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2899 | - | 6e-69 | 94.12% (136) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv1931c | - | 2e-08 | 34.57% (81) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4709c | - | 2e-27 | 46.28% (121) | AraC family transcriptional regulator |
| M. marinum M | MMAR_1063 | - | 6e-12 | 30.61% (98) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 2e-07 | 29.09% (110) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_0213 | - | 1e-26 | 43.90% (123) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4270 | - | 8e-10 | 33.01% (103) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | MUL_0821 | - | 4e-12 | 30.61% (98) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3612|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2899|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4709c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0213|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1063|M.marinum_M -------------------------MAQAARLIQHRSGVPIYGYRTDPDI
MUL_0821|M.ulcerans_Agy99 -------------------MDYLWRMAQAARLIQHRSGVPIYGYRTDPDI
Mb1966c|M.bovis_AF2122/97 --------------------------------------MVIVGFPGDPVD
Rv1931c|M.tuberculosis_H37Rv --------------------------------------MVIVGFPGDPVD
MAV_4981|M.avium_104 ---------MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEANRFGADY
TH_4270|M.thermoresistible__bu MKDGPLLELGRVRDRDQIRAAVADIFCPHGLDVRKGSGLDASVRAQAAGS
Mvan_3612|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2899|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4709c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0213|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1063|M.marinum_M PRVSVLRPGPEDLGDRARHIHDFPALWYVPAAGLVYIAAAGQVLEPTQFG
MUL_0821|M.ulcerans_Agy99 PRVSVRRPGPEDLGDRARHIHDFPALWYVPAAGLVYIAAAGQVLEPTQFG
Mb1966c|M.bovis_AF2122/97 TVILPGGAGVDAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLG
Rv1931c|M.tuberculosis_H37Rv TVILPGGAGVDAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLG
MAV_4981|M.avium_104 LLKIASVDGRDVTTSIGTRLGVTDAVSSIESADTVLVAGSDNLPRRPIDP
TH_4270|M.thermoresistible__bu IKLVWVTYGAPVRIDVPPPSEPFHLVQIPLQGYLSVTSGDEEVVSDSALA
Mvan_3612|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2899|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4709c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0213|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1063|M.marinum_M SLQGGVAMFFDPAALGGDGGSPWPSWRTHPLLFPFLHGHSGGILRLEVPA
MUL_0821|M.ulcerans_Agy99 SLQAGVAMFFDPAALGGDGGSPWPSWRTHPLLFPFLHGHSGGILRLEVPA
Mb1966c|M.bovis_AF2122/97 RTPSDDALGLCRTFRPRISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRA
Rv1931c|M.tuberculosis_H37Rv RTPSDDALGLCRTFRPRISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRA
MAV_4981|M.avium_104 ELVEAVKSVADRTRRLASICTGSFILGQAGLLDGRRATTHWHDVRLFARA
TH_4270|M.thermoresistible__bu SMPDPRLPCTMRWEAHCSEVIVRIDDDVLHRHLESLLGHPVKAPLHFSLG
Mvan_3612|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2899|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4709c|M.abscessus_ATCC_199 ---------------------------------MLFGTNLGTVTSAGE--
MSMEG_0213|M.smegmatis_MC2_155 --------------------------------------------MPGE--
MMAR_1063|M.marinum_M ARRSTWDGAIAAIEAELTARQQGYGQAVAAHLTLLLIELARLARDVVG--
MUL_0821|M.ulcerans_Agy99 ARRSTWDGAIAAIEAELTTRQQGYGQAVTAHLTLLLIELARLARDVVG--
Mb1966c|M.bovis_AF2122/97 G------------TGRRRPRHRDCPDGCPLARPVSAPTRWADPVRGSG--
Rv1931c|M.tuberculosis_H37Rv G------------TGRRRPRHRDCPDGCPLARPVSAPTRWADPVRGSG--
MAV_4981|M.avium_104 FPEITVEPDALFVCDGDVFTSAGISSGIDLALALVEMDYGTELVRAVARW
TH_4270|M.thermoresistible__bu MPLDSGPGSSWRAAIDMMITELDRDGGLLKFPLVSAQLESLILTGLLTAQ
Mvan_3612|M.vanbaalenii_PYR-1 --------------------MLPPARYLMRAKDLVDARYSEPITVDDLAA
Mflv_2899|M.gilvum_PYR-GCK ----------------------------MRAKDLVDARYAEPITVDDLAA
MAB_4709c|M.abscessus_ATCC_199 ------------------EQRLRDLARLRRVRDRIDREYAQPLNVEALAR
MSMEG_0213|M.smegmatis_MC2_155 ------------------EQRLRDLKLLRRVRDRIDREYAQPLNVEALAR
MMAR_1063|M.marinum_M ------------------DLRRSGEPLLAEVFEVIDRRHAEPLSLRDVAA
MUL_0821|M.ulcerans_Agy99 ------------------DLRRSGEPLLAEVFEVIDRRHAEPLSLRDVAA
Mb1966c|M.bovis_AF2122/97 ------------------VDATRQTDLDPPGAGGHRGRAGGAHRIGELAQ
Rv1931c|M.tuberculosis_H37Rv ------------------VDATRQTDLDPPGAGGHRGRAGGAHRIGELAQ
MAV_4981|M.avium_104 LVVYLKRAGGQSQFSALVEAEPPPRSPLRKVTAAISADPAADHSVKSLSA
TH_4270|M.thermoresistible__bu PHN--------YTTALLADSGPAPPRAIRRALDYIESESDRAITTARLAA
::
Mvan_3612|M.vanbaalenii_PYR-1 AAGLSRAHFSRMFSKTFGESPRAYLQTRRLERAASLLRHTD----RSVAD
Mflv_2899|M.gilvum_PYR-GCK AAGLSRAHFSRMFTRTFGESPRAYLQTRRLERAASLLRHTD----RSVAD
MAB_4709c|M.abscessus_ATCC_199 EAQMSAGHLSRQFKSAYGESPYSYLMTRRIERAMMLLRRGD----MSVTD
MSMEG_0213|M.smegmatis_MC2_155 GVNMSAGHLSRQFKAAFGESPYSYLMTRRIERAMALLRRGD----LSVTE
MMAR_1063|M.marinum_M EVGMTPGHLTTIVRRRTGRTVQEWIIERRMAQARELLVATD----LAVGE
MUL_0821|M.ulcerans_Agy99 EVGMTPGHLTTIVRRRTGRTVQEWIIERRMAQARELLVATD----LAVGE
Mb1966c|M.bovis_AF2122/97 RAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETH----DTVVA
Rv1931c|M.tuberculosis_H37Rv RAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQLEETH----DTVVA
MAV_4981|M.avium_104 RASLSTRQLTRLFQSELGTTPARYVEMVRIDAARAALDAG-----RSVAE
TH_4270|M.thermoresistible__bu HVGISARALQRGFQEHVGCSPMDYLRDVRLRRARDLLSEADPSAEVTVTE
. :: : . * : :: * * * :*
Mvan_3612|M.vanbaalenii_PYR-1 ICVMVGLQSVGSFTTSFARTYGMPPAAYRASMPPAAVHARIPSCILQRDT
Mflv_2899|M.gilvum_PYR-GCK ICVMVGLQSVGSFTTSFARAYGLPPAAYRASMPSAAVHARIPSCILQRDT
MAB_4709c|M.abscessus_ATCC_199 VCFAVGCSSLGTFSTRFAELVGMSPRTYKER--IVD-HAGIPSCVVKQVT
MSMEG_0213|M.smegmatis_MC2_155 VCFAVGCSSLGTFSTRFTELVGLPPSTYRDR--AAAIQEGLPSCLEKYVT
MMAR_1063|M.marinum_M VARRVGISDPGYFSRLFSRAHGTSPRQWRAL-------------------
MUL_0821|M.ulcerans_Agy99 VARRVGISDPGYFSRLFSRAHGTSPRQWRAL-------------------
Mb1966c|M.bovis_AF2122/97 IAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-----------------
Rv1931c|M.tuberculosis_H37Rv IAARCGFGTAETMRRSFIRRVGISPDQYRKAFA-----------------
MAV_4981|M.avium_104 SARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRTAARG------------
TH_4270|M.thermoresistible__bu VALECGFMHLGRFSVEYRRRFGESPSETLRR-------------------
. * : : . * .*
Mvan_3612|M.vanbaalenii_PYR-1 RPKADTRVDKTAHGEKTG-----
Mflv_2899|M.gilvum_PYR-GCK RPKADSRV-KTAHGEKTGANASP
MAB_4709c|M.abscessus_ATCC_199 RPIRNREATPAVRG---------
MSMEG_0213|M.smegmatis_MC2_155 RPVRNREA-PAVRLHLA------
MMAR_1063|M.marinum_M -PPRH------------------
MUL_0821|M.ulcerans_Agy99 -PPRH------------------
Mb1966c|M.bovis_AF2122/97 -----------------------
Rv1931c|M.tuberculosis_H37Rv -----------------------
MAV_4981|M.avium_104 -----------------------
TH_4270|M.thermoresistible__bu -----------------------