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MPRGGPDASCLDRLLQTDRQEYLDRDSAGDAGLEQTKRSVIRALDWTGEVFGNHEKFAKIALDEVADVAD PRILELGAGHGGLSRKLLEWHPSARLTVTDVEPASVAAIAAGDLGSHPRATVRQMDATALDAADGEFDLA VFALSFHHLPPQLAARAIAEGARVADKLLIIDLPRPPAPLHVLRLAAMLPWAPLVPFLHDGVISSLRAYS PSALRALATHADPAVDIELRGGLLSPQVAVATRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5469 | - | - | 100% (244) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_5517 | - | 1e-08 | 33.33% (111) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_2318 | - | 5e-06 | 35.48% (93) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2000 | - | 3e-66 | 51.94% (258) | hypothetical protein Mb2000 |
| M. gilvum PYR-GCK | Mflv_1326 | - | 1e-110 | 79.92% (244) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1978 | - | 5e-67 | 52.33% (258) | hypothetical protein Rv1978 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4700c | - | 6e-81 | 63.82% (246) | hypothetical protein MAB_4700c |
| M. marinum M | MMAR_1415 | - | 2e-11 | 43.42% (76) | hypothetical protein MMAR_1415 |
| M. avium 104 | MAV_0081 | - | 2e-59 | 52.54% (236) | hypothetical protein MAV_0081 |
| M. smegmatis MC2 155 | MSMEG_6231 | - | 9e-96 | 72.02% (243) | hypothetical protein MSMEG_6231 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0820 | - | 1e-07 | 30.71% (140) | methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2000|M.bovis_AF2122/97 MGEANIREQAIATMPRGGPDASWLDRRFQTDALEYLDRDDVP----DEVK
Rv1978|M.tuberculosis_H37Rv MGEANIREQAIATMPRGGPDASWLDRRFQTDALEYLDRDDVP----DEVK
MAV_0081|M.avium_104 MSEALTVDPAIASMPRGGPDASWLDRRLQTEKLEYTDRYDIP----DEVK
Mvan_5469|M.vanbaalenii_PYR-1 -------------MPRGGPDASCLDRLLQTDRQEYLDRDSAGDAGLEQTK
Mflv_1326|M.gilvum_PYR-GCK -------------MPRGGPRASCLDRLLETDRQEYLDRASELPADVAR-K
MSMEG_6231|M.smegmatis_MC2_155 MAYMATSTADIAAMPRGGPRASCLDRLLQTDRLEYLDRDDVD----QRVK
MAB_4700c|M.abscessus_ATCC_199 MFYVENSARDISSMPRGGPNASWLDRRLQTDRLEYLDRDDVD-----DLK
MMAR_1415|M.marinum_M -------------MPAMSRIESVFCRSAPWR----------------AAT
MUL_0820|M.ulcerans_Agy99 -------------MTNHHPRFGLQHSGESRDYLP------------AAGH
*. .
Mb2000|M.bovis_AF2122/97 QKIIGVLDRVG--TLTNLHEKYARIALKLVSDIPNPRILELGAGHGKLSA
Rv1978|M.tuberculosis_H37Rv QKIIGVLDRVG--TLTNLHEKYARIALKLVSDIPNPRILELGAGHGKLSA
MAV_0081|M.avium_104 QTVVAALDRMG--TRAGYHERNARTALDIVADIANPRILELGAGHGKLSA
Mvan_5469|M.vanbaalenii_PYR-1 RSVIRALDWTG--EVFGNHEKFAKIALDEVADVADPRILELGAGHGGLSR
Mflv_1326|M.gilvum_PYR-GCK RSVIRALEWTG--ETFGHHVRFAEIVLDQISDVPDPKILELGAGHGALSR
MSMEG_6231|M.smegmatis_MC2_155 RSVVRALEWTG--DMFGNHEKFAAISLDLLAEVPDPRILELGAGHGSVSR
MAB_4700c|M.abscessus_ATCC_199 RRVMQSLDRAGRRRWIGIHEKCARMAIREVADVDRPKILELGAGLGGLSH
MMAR_1415|M.marinum_M RRLVLPWALQG------------------IEPVG--EVLEIGAGSGAMAA
MUL_0820|M.ulcerans_Agy99 DALLPAYDLLS---RLLGMNKIHRTLITQAELADCGRILEIGCGTGNLAI
:: . .:**:*.* * ::
Mb2000|M.bovis_AF2122/97 KILELHPTATVTISDLDPTSVANIAAGELGTHPRARTQVIDATAIDGHGH
Rv1978|M.tuberculosis_H37Rv KILELHPTATVTISDLDPTSVANIAAGELGTHPRARTQVIDATAIDGHDH
MAV_0081|M.avium_104 EILTSHPTATVTVSDLDPTSVANIAAGPLGADPRARTQVVDATAIDAPDD
Mvan_5469|M.vanbaalenii_PYR-1 KLLEWHPSARLTVTDVEPASVAAIAAGDLGSHPRATVRQMDATALDAADG
Mflv_1326|M.gilvum_PYR-GCK KLLDWHPTARLTVTDIEPASVAAIADSDVGAHPRATVRQMDATALDAADG
MSMEG_6231|M.smegmatis_MC2_155 RLLANHPTAHVTVTDVDPAAVAAMADGELGDHPRAVVRAMDATDIDADDG
MAB_4700c|M.abscessus_ATCC_199 KLLEMHSTAQVTVTDVDPSFVAAVAAGEIGSHPRATVRQLDATEIDSPGG
MMAR_1415|M.marinum_M EMLAAQPDTRITVTDYDDAMVAAAAQRLAPFQTRATARQADATALPFGDN
MUL_0820|M.ulcerans_Agy99 KAKRAQPRAEVIGSDPDPRALQRAQR-KTGNVEEVRFDQGYAQRLPYADG
. :. : : :* : : .. * : .
Mb2000|M.bovis_AF2122/97 SYDLAVFALAFHHLP-------PTVACKAIAEATRVGKRFLIIDLKRQKP
Rv1978|M.tuberculosis_H37Rv SYDLAVFALAFHHLP-------PTVACKAIAEATRVGKRFLIIDLKRQKP
MAV_0081|M.avium_104 SYDLVVFAQAFHHLP-------PATAVRAIAEATRVGKRFLVIDLPRPRS
Mvan_5469|M.vanbaalenii_PYR-1 EFDLAVFALSFHHLP-------PQLAARAIAEGARVADKLLIIDLPRP--
Mflv_1326|M.gilvum_PYR-GCK EFDLAVFALSFHHLP-------PAAAARVIAEGTRAADTLLIIDLPRP--
MSMEG_6231|M.smegmatis_MC2_155 SFDLALFALSFHHLS-------PAQAAAVFAEGTRVARTLLIIDLPRP--
MAB_4700c|M.abscessus_ATCC_199 YYDLAVFALSLHHLP-------PELAARVFATGTRVARKLLIVDLPRP--
MMAR_1415|M.marinum_M TFDTVLTFIMLHHTVRWEQ--TLAEAVRVLAPHGTLIGYDLLSSWPTR--
MUL_0820|M.ulcerans_Agy99 EFDRVLSSMMLHHLDEDAKSAAAAEAFRVLRPGGRLHLVDVGGDMSAHDG
:* .: :** * .: : .
Mb2000|M.bovis_AF2122/97 LSFTLSSVLLLPLH-LLLLPWSS-MRSSMHDG--FISALRAYSPSALQTL
Rv1978|M.tuberculosis_H37Rv LSFTLSSVLLLPLH-LLLLPWSS-MRSSMHDG--FISALRAYSPSALQTL
MAV_0081|M.avium_104 VQLLLTPLILAPFAAALALVRPS-LKHVMHDA--YISALRAYSRSAFIAL
Mvan_5469|M.vanbaalenii_PYR-1 ------PAPLHVLRLAAMLPWAP-LVPFLHDG--VISSLRAYSPSALRAL
Mflv_1326|M.gilvum_PYR-GCK ------PAPLHLVRLATMLPWAP-LVPFVHDG--VISSLRAYSPAALRAL
MSMEG_6231|M.smegmatis_MC2_155 ------PAPLHLLRLATMLPLAP-LVPFVHDG--VISSLRCYSPSALRAL
MAB_4700c|M.abscessus_ATCC_199 ------PVPLHLALLAVVLPLVA-ISPLQHDG--FISSLRAYSPSALRAL
MMAR_1415|M.marinum_M ------TLHRLEGAPHRLIERGE-LQPVLRQL--PLSASRVRQNRLLVRF
MUL_0820|M.ulcerans_Agy99 -----LASRFIRHNLHVAGNLGDGIRRLLDTAGFDVAEVGAQRHPLLGRL
. : :: : :
Mb2000|M.bovis_AF2122/97 ARAADPGMQVEILP-APTRLFPPSLAVVFSRSSSAPTESSECSADRQPGE
Rv1978|M.tuberculosis_H37Rv ARAADPGMQVEILP-APTRLFPPSLAVVFSRSSSAPTESSECSADRQPGE
MAV_0081|M.avium_104 GKAADPRMGVEFLPLSACRLRPGHVGIVFTRPRAS---------------
Mvan_5469|M.vanbaalenii_PYR-1 ATHADPAVDIELRG---G-LLSPQVAVATRR-------------------
Mflv_1326|M.gilvum_PYR-GCK AAHAGEDIDIELRG---G-LFSPQVAVAARR-------------------
MSMEG_6231|M.smegmatis_MC2_155 AAHAG--VALELRG---G-LTTPQIAIARRA-------------------
MAB_4700c|M.abscessus_ATCC_199 AHHADPAINVEFRS---RRGLGPTVVVASRP-------------------
MMAR_1415|M.marinum_M TAMKQASPS-----------------------------------------
MUL_0820|M.ulcerans_Agy99 VYYRATRPCA----------------------------------------