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NEAHRLCGSDQWRQMIRDVILPWAMGDHRLGDDVLEVGPGYGATTDVLCTEVARLTAVEIDPDLAAMLID RFADQPSVQIVNGDAAALDYPDGRFTGAACFTMLHHVEPSQRQDRLFAEIARVLRPGAVLVASDSLASEP LQQMHDGDTYNPVDPQTLPGRLEAAGFTDVEVQTNEFGWSAVAHRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2318 | - | - | 100% (187) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_2098 | - | 1e-07 | 39.45% (109) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_5517 | - | 2e-07 | 31.97% (147) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3862c | - | 9e-40 | 46.43% (168) | hypothetical protein Mb3862c |
| M. gilvum PYR-GCK | Mflv_4035 | - | 3e-08 | 31.45% (159) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3832c | - | 9e-40 | 46.43% (168) | hypothetical protein Rv3832c |
| M. leprae Br4923 | MLBr_01713 | - | 1e-06 | 28.70% (115) | hypothetical protein MLBr_01713 |
| M. abscessus ATCC 19977 | MAB_2704 | - | 6e-37 | 46.88% (160) | hypothetical protein MAB_2704 |
| M. marinum M | MMAR_2358 | - | 9e-42 | 48.57% (175) | hypothetical protein MMAR_2358 |
| M. avium 104 | MAV_0196 | - | 4e-39 | 45.16% (186) | hypothetical protein MAV_0196 |
| M. smegmatis MC2 155 | MSMEG_5438 | ksgA | 1e-06 | 52.63% (57) | dimethyladenosine transferase |
| M. thermoresistible (build 8) | TH_0087 | - | 4e-07 | 33.93% (112) | methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_1534 | - | 5e-41 | 47.43% (175) | hypothetical protein MUL_1534 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3862c|M.bovis_AF2122/97 ------------------MAMNLLHRRHCSSAGWEK---------AVANQ
Rv3832c|M.tuberculosis_H37Rv ------------------MAMNLLHRRHCSSAGWEK---------AVANQ
MAV_0196|M.avium_104 ---------------MIAMAMNLLHRHRCSSAGWAK---------EVADE
MMAR_2358|M.marinum_M ------------------MAMNLVHRLCCDSDRWAN---------EVKGQ
MUL_1534|M.ulcerans_Agy99 ------------------MAMNLVHRLCCDSDRWAN---------EVKGQ
MAB_2704|M.abscessus_ATCC_1997 --------------------------------MWAR---------KTESQ
Mvan_2318|M.vanbaalenii_PYR-1 --------------------MNEAHR-LCGSDQWRQ---------MIRDV
Mflv_4035|M.gilvum_PYR-GCK ----MDGSERPVNHHGDHPGFSGLTGQLCAVAFLLT---------GRETG
TH_0087|M.thermoresistible__bu ----------------------------MLTVDYDR---------LGIGP
MLBr_01713|M.leprae_Br4923 MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQ
MSMEG_5438|M.smegmatis_MC2_155 -----------------MAKEIDFRPRKAFGQNFVH---------DANTV
Mb3862c|M.bovis_AF2122/97 LLPWALQHVELGPRTLEIGPGYGATLQALLGLTASLTAVEVDNSMVERLN
Rv3832c|M.tuberculosis_H37Rv LLPWALQHVELGPRTLEIGPGYGATLQALLGLTASLTAVEVDNSMVERLN
MAV_0196|M.avium_104 LLPWALDGVELGSRTLEIGPGYGATLSALLDRTASLTAVELDPVMADRLQ
MMAR_2358|M.marinum_M VLPWVLADVDLGDNVLEIGPGYGAFLRVLVDKTPKLTAVEIDPAMARRLQ
MUL_1534|M.ulcerans_Agy99 VFPWVLADVDLGDNALEIGPGYGAFLRVLVDKTPKLTAVEIDPAMARRLQ
MAB_2704|M.abscessus_ATCC_1997 LLPWALQGVELGADTLEIGPGYGANLRVLTNRTPQLTAVEIDETMATRLQ
Mvan_2318|M.vanbaalenii_PYR-1 ILPWAMGDHRLGDDVLEVGPGYGATTDVLCTEVARLTAVEIDPDLAAMLI
Mflv_4035|M.gilvum_PYR-GCK RLAADLTAVSATDHVLDIGCGPGNACRIAAARGARVTGVDPSAAMLR-VA
TH_0087|M.thermoresistible__bu GVSVIDVGCGLGRHSFEAYRR-GAHIVAFDQNAEELNEVDTILQAMAEQR
MLBr_01713|M.leprae_Br4923 VVYQWLAQRCTGCEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVAHVR
MSMEG_5438|M.smegmatis_MC2_155 RRIVSASGVHRHDHVLEVGPGLGSLTLALLDRGARVTAVEIDPLLARQLP
:: * : *:
Mb3862c|M.bovis_AF2122/97 RRYGQR---------------ARIIRGDG--------TQTGLPDDHFTSV
Rv3832c|M.tuberculosis_H37Rv RRYGQR---------------ARIIRGDG--------TQTGLPDDHFTSV
MAV_0196|M.avium_104 RRYGDR---------------ARVIQASG--------TETGLPANHFTSV
MMAR_2358|M.marinum_M ERYGEQ---------------ARIINGDG--------TDTGLPAEEFSSV
MUL_1534|M.ulcerans_Agy99 ERYGEQ---------------ARIINGDG--------TDTGLPAEEFSSV
MAB_2704|M.abscessus_ATCC_1997 RLYGDR---------------ATVMQGDG--------TKLGFDNDRFSSV
Mvan_2318|M.vanbaalenii_PYR-1 DRFADQPS-------------VQIVNGDA--------AALDYPDGRFTGA
Mflv_4035|M.gilvum_PYR-GCK RIVTHGAS-------------VTWVRGGA--------EALPVPDAGATVA
TH_0087|M.thermoresistible__bu EAPAGAR--------------AEVVKGDA--------LDLPYADGTFDRV
MLBr_01713|M.leprae_Br4923 SRYPRV----------------QVMQANL--------IELPLADASVDVV
MSMEG_5438|M.smegmatis_MC2_155 TTIADHSHSEINRLTVLNRDILTLMPGDLEEQPTALVANLPYNVAVPALL
: ..
Mb3862c|M.bovis_AF2122/97 VCFTMLHHVASAQLQDQLFAEAYRVLQPGGVFAGSDG-------------
Rv3832c|M.tuberculosis_H37Rv VCFTMLHHVASAQLQDQLFAEAYRVLQPGGVFAGSDG-------------
MAV_0196|M.avium_104 VCFTMLHHVPSPQLQDQLFAEALRVLQPGGTFAGSDG-------------
MMAR_2358|M.marinum_M VSFTMLHHVPTTELQDELFAEAYRVLRPGGVFAGSDG-------------
MUL_1534|M.ulcerans_Agy99 VSFTMLHHVPTTELQDELFAEAYRVLRPGGVFAGSDG-------------
MAB_2704|M.abscessus_ATCC_1997 VCFTMLHHVPTADLQDQLFAQAHRVLAPGGVFAGSDG-------------
Mvan_2318|M.vanbaalenii_PYR-1 ACFTMLHHVEPSQRQDRLFAEIARVLRPGAVLVASDS-------------
Mflv_4035|M.gilvum_PYR-GCK WALATVHHWPDVDAG---LAEIHRALGPGARFLAVER-------------
TH_0087|M.thermoresistible__bu IASEILEHVPE---DDRAIAELVRVLKPGGKLVVTVP-------------
MLBr_01713|M.leprae_Br4923 VNFQVIEHLWN---QAQFVSECARVLRPSGLLMVSTPNRITFSPGRDTSI
MSMEG_5438|M.smegmatis_MC2_155 HLLAEFPSIRTVMVMVQAEVAERLAAEPGGKDYGVPSAKVRFYG------
. . *..
Mb3862c|M.bovis_AF2122/97 -------VPSLPFRLIHIADTYTPIA--------PADLPGRLRAVGFTDI
Rv3832c|M.tuberculosis_H37Rv -------VPSLPFRLIHIADTYTPIA--------PADLPGRLRAVGFTDI
MAV_0196|M.avium_104 -------VPSWVFRLLHVADTYNPIA--------PKDLPGRLAAAGFADI
MMAR_2358|M.marinum_M -------IPSLLFSILHFRDTCNPIP--------PTDLPDRLRAAGFHDV
MUL_1534|M.ulcerans_Agy99 -------IPSLLFSILHFRDTCNPIP--------PTDLPDRLRAAGFHDV
MAB_2704|M.abscessus_ATCC_1997 -------VHSTFFRLLHIGDTYNPVP--------TTSLPDRLRAAGFTDI
Mvan_2318|M.vanbaalenii_PYR-1 -------LASEPLQQMHDGDTYNPVD--------PQTLPGRLEAAGFTDV
Mflv_4035|M.gilvum_PYR-GCK -------QTEPDATGISSHG-WTGAQ--------AETFAAMCESAGLTTV
TH_0087|M.thermoresistible__bu -------RWLPERICWLLSDEYHANEGGHVRIYRADELRDKITRHGLRLT
MLBr_01713|M.leprae_Br4923 NPFHTRELNADELTQLLITADFSEVAMYG--LFHGPRLKEMDARHGGSII
MSMEG_5438|M.smegmatis_MC2_155 --NVRRHGMVSPTVFWPIPRVYSGLVRIDRYETSPWPMDEAFRDEVFNLI
:
Mb3862c|M.bovis_AF2122/97 HVDVAGA-------RLRWRATKPVAA------------------------
Rv3832c|M.tuberculosis_H37Rv HVDVAGA-------RLRWRATKPVAA------------------------
MAV_0196|M.avium_104 HADARGG-------RQRWRAVKPID-------------------------
MMAR_2358|M.marinum_M EVEVQAG-------RQRWRAQKPKV-------------------------
MUL_1534|M.ulcerans_Agy99 EVEVQAG-------RQRWRAQKPKA-------------------------
MAB_2704|M.abscessus_ATCC_1997 EHHLDGG-------NQRWRAVKAA--------------------------
Mvan_2318|M.vanbaalenii_PYR-1 EVQTN---------EFGWSAVAHRA-------------------------
Mflv_4035|M.gilvum_PYR-GCK RVGSGRAG-----KRRVWTVHATRP-------------------------
TH_0087|M.thermoresistible__bu HRHHAHAL-----HSPFWWLKCAVGTNNDRHFAVRAYHQLLVWDMVRRPW
MLBr_01713|M.leprae_Br4923 DAQIARAV-----SNAPWPPELVADVAAVTAADFDIIEASAGPEASDGRD
MSMEG_5438|M.smegmatis_MC2_155 DIGFAQRRKTSRNAFAEWAGGGNESAERLLAARIDPARRGETLSINDFVR
*
Mb3862c|M.bovis_AF2122/97 -------------------------------
Rv3832c|M.tuberculosis_H37Rv -------------------------------
MAV_0196|M.avium_104 -------------------------------
MMAR_2358|M.marinum_M -------------------------------
MUL_1534|M.ulcerans_Agy99 -------------------------------
MAB_2704|M.abscessus_ATCC_1997 -------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 -------------------------------
Mflv_4035|M.gilvum_PYR-GCK -------------------------------
TH_0087|M.thermoresistible__bu VTRWAEEMLNPLIGKSVALYFDKPEVAGADS
MLBr_01713|M.leprae_Br4923 VDESLDLIAIAVRR-----------------
MSMEG_5438|M.smegmatis_MC2_155 LLQRTKEALGEDYTKQVARPSASAPSVSAEA