For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPAMSRIESVFCRSAPWRAATRRLVLPWALQGIEPVGEVLEIGAGSGAMAAEMLAAQPDTRITVTDYDDA MVAAAAQRLAPFQTRATARQADATALPFGDNTFDTVLTFIMLHHTVRWEQTLAEAVRVLAPHGTLIGYDL LSSWPTRTLHRLEGAPHRLIERGELQPVLRQLPLSASRVRQNRLLVRFTAMKQASPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1415 | - | - | 100% (197) | hypothetical protein MMAR_1415 |
| M. marinum M | MMAR_2358 | - | 4e-13 | 33.11% (151) | hypothetical protein MMAR_2358 |
| M. marinum M | MMAR_1663 | - | 4e-11 | 32.14% (112) | hypothetical protein MMAR_1663 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3862c | - | 4e-17 | 35.76% (151) | hypothetical protein Mb3862c |
| M. gilvum PYR-GCK | Mflv_2862 | - | 6e-13 | 34.31% (137) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3832c | - | 4e-17 | 35.76% (151) | hypothetical protein Rv3832c |
| M. leprae Br4923 | MLBr_01723 | - | 3e-11 | 34.31% (102) | hypothetical protein MLBr_01723 |
| M. abscessus ATCC 19977 | MAB_2704 | - | 2e-17 | 40.15% (137) | hypothetical protein MAB_2704 |
| M. avium 104 | MAV_0196 | - | 6e-17 | 36.42% (151) | hypothetical protein MAV_0196 |
| M. smegmatis MC2 155 | MSMEG_6231 | - | 7e-11 | 37.38% (107) | hypothetical protein MSMEG_6231 |
| M. thermoresistible (build 8) | TH_2189 | - | 3e-12 | 33.93% (112) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1534 | - | 2e-12 | 31.79% (151) | hypothetical protein MUL_1534 |
| M. vanbaalenii PYR-1 | Mvan_2318 | - | 3e-14 | 33.80% (142) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu VIRRLMATALTALTTAVLAGCGDAGSWVEAKPAEGWSAQYGDAANSSYTS
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1415|M.marinum_M --------------------------------------------------
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6231|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu AAGAEALTLEWSRSVKGELAAQVAVGASGYLAVNAQTPAGCSLMVWEYAN
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1415|M.marinum_M --------------------------------------------------
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6231|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu SARQRWCTRLVQGGGRTSPLLDGFDNVYIGQPGAILSFPPTQWIRWRKPV
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1415|M.marinum_M --------------------------------------------------
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6231|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu IGMPTTPRILAPGELLVVTHLGQVLLFDAHRGTVTGTPLDLVAGVDPTDS
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1415|M.marinum_M --------------------------------------------------
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6231|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 ------------------------------------------MTRSTEIS
TH_2189|M.thermoresistible__bu ERGLADCAGARXXXCWPPPRPPSTVTPRARDAARHPTARLPAMTETTEPG
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1415|M.marinum_M --------------------------------------------------
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6231|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 AN-------AVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYDEKWSIS
TH_2189|M.thermoresistible__bu IGSEGAGDLPAPNPHATAEQVEAAMRDSKLAQILYHDWEAESYDDKWSIS
Mb3862c|M.bovis_AF2122/97 --------------------------------------MAMNLLHRRHCS
Rv3832c|M.tuberculosis_H37Rv --------------------------------------MAMNLLHRRHCS
MAV_0196|M.avium_104 -----------------------------------MIAMAMNLLHRHRCS
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------MAMNLVHRLCCD
Mvan_2318|M.vanbaalenii_PYR-1 ----------------------------------------MNEAHR-LCG
MMAR_1415|M.marinum_M -------------------------------------MPAMSRIESVFCR
Mflv_2862|M.gilvum_PYR-GCK ----------------------------------------MNMAETALIN
MSMEG_6231|M.smegmatis_MC2_155 ---MAYMATSTADIAAMPRGGPRASCLDRLLQTDRLEYLDRDDVDQRVKR
MLBr_01723|M.leprae_Br4923 YDQRCVDYVRHCFDAIVPDELFT-----ELPYDCALELGCGTGFFLLNLI
TH_2189|M.thermoresistible__bu YDQRCVDYARGRFDAIVPDHVQR-----ELPYDNALELGCGTGFFLLNLI
Mb3862c|M.bovis_AF2122/97 SAG----WEKAVANQLLPWALQH-----VELGPRTLEIGPGYGATLQALL
Rv3832c|M.tuberculosis_H37Rv SAG----WEKAVANQLLPWALQH-----VELGPRTLEIGPGYGATLQALL
MAV_0196|M.avium_104 SAG----WAKEVADELLPWALDG-----VELGSRTLEIGPGYGATLSALL
MAB_2704|M.abscessus_ATCC_1997 --M----WARKTESQLLPWALQG-----VELGADTLEIGPGYGANLRVLT
MUL_1534|M.ulcerans_Agy99 SDR----WANEVKGQVFPWVLAD-----VDLGDNALEIGPGYGAFLRVLV
Mvan_2318|M.vanbaalenii_PYR-1 SDQ----WRQMIRDVILPWAMGD-----HRLGDDVLEVGPGYGATTDVLC
MMAR_1415|M.marinum_M SAP----WRAATRRLVLPWALQG-----IEPVGEVLEIGAGSGAMAAEML
Mflv_2862|M.gilvum_PYR-GCK SAPR--RWLQRVYEVPVLLRFGGR----LVPDTQALEIGCGSGYGTQLIL
MSMEG_6231|M.smegmatis_MC2_155 SVVRALEWTGDMFGNHEKFAAISLDLLAEVPDPRILELGAGHGSVSRRLL
: **:* * * :
MLBr_01723|M.leprae_Br4923 QSGVARRGSVTDLSPGMVK-IATRNGQSL-GLDINGR--VADAEGIPYDD
TH_2189|M.thermoresistible__bu QSGVARRGSVTDLSPGMVR-VATRNGRSL-GLDVDGR--VADAEGIPYDD
Mb3862c|M.bovis_AF2122/97 G--LTASLTAVEVDNSMVERLNRRYGQR---ARIIR----GDGTQTGLPD
Rv3832c|M.tuberculosis_H37Rv G--LTASLTAVEVDNSMVERLNRRYGQR---ARIIR----GDGTQTGLPD
MAV_0196|M.avium_104 D--RTASLTAVELDPVMADRLQRRYGDR---ARVIQ----ASGTETGLPA
MAB_2704|M.abscessus_ATCC_1997 N--RTPQLTAVEIDETMATRLQRLYGDR---ATVMQ----GDGTKLGFDN
MUL_1534|M.ulcerans_Agy99 D--KTPKLTAVEIDPAMARRLQERYGEQ---ARIIN----GDGTDTGLPA
Mvan_2318|M.vanbaalenii_PYR-1 T--EVARLTAVEIDPDLAAMLIDRFADQP-SVQIVN----GDAAALDYPD
MMAR_1415|M.marinum_M AAQPDTRITVTDYDDAMVAAAAQRLAPFQ-TRATAR---QADATALPFGD
Mflv_2862|M.gilvum_PYR-GCK ERFGAATVDAVDLDPAMIRRAGERLARYGNRVRLVQGSATDLSTALDAGD
MSMEG_6231|M.smegmatis_MC2_155 ANHPTAHVTVTDVDPAAVAAMADGELGDH-PRAVVR---AMDATDIDADD
..: . .
MLBr_01723|M.leprae_Br4923 NTFDLVVGHAVLHHIPDVELS---LREVLRVLKPGGRFVFAGEPTDVGNR
TH_2189|M.thermoresistible__bu NTFDLVVGHAVLHHIPDVELS---LREVVRVLRPGGRFVFAGEPTTVGNS
Mb3862c|M.bovis_AF2122/97 DHFTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGG--VFAGS-------
Rv3832c|M.tuberculosis_H37Rv DHFTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGG--VFAGS-------
MAV_0196|M.avium_104 NHFTSVVCFTMLHHVPSPQLQDQLFAEALRVLQPGG--TFAGS-------
MAB_2704|M.abscessus_ATCC_1997 DRFSSVVCFTMLHHVPTADLQDQLFAQAHRVLAPGG--VFAGS-------
MUL_1534|M.ulcerans_Agy99 EEFSSVVSFTMLHHVPTTELQDELFAEAYRVLRPGG--VFAGS-------
Mvan_2318|M.vanbaalenii_PYR-1 GRFTGAACFTMLHHVEPSQRQDRLFAEIARVLRPGA--VLVAS-------
MMAR_1415|M.marinum_M NTFDTVLTFIMLHHTVRWEQT---LAEAVRVLAPHG--TLIGY-------
Mflv_2862|M.gilvum_PYR-GCK GSYGAVFDFGIVHHIPDWRNA---VAEVARVLAPGGRFYFDEVT------
MSMEG_6231|M.smegmatis_MC2_155 GSFDLALFALSFHHLSPAQAA-AVFAEGTRVARTLLIIDLPRP-------
: . .** . : ** . :
MLBr_01723|M.leprae_Br4923 YARVFADLTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLH--
TH_2189|M.thermoresistible__bu YARALSTLTWHVATTVTRLPGLQGWRRPQAELDESSRAAALEAVVDLH--
Mb3862c|M.bovis_AF2122/97 ---------------------------------DGVPSLPFRLIHIAD--
Rv3832c|M.tuberculosis_H37Rv ---------------------------------DGVPSLPFRLIHIAD--
MAV_0196|M.avium_104 ---------------------------------DGVPSWVFRLLHVAD--
MAB_2704|M.abscessus_ATCC_1997 ---------------------------------DGVHSTFFRLLHIGD--
MUL_1534|M.ulcerans_Agy99 ---------------------------------DGIPSLLFSILHFRD--
Mvan_2318|M.vanbaalenii_PYR-1 ---------------------------------DSLASEPLQQMHDGD--
MMAR_1415|M.marinum_M ---------------------------------DLLSSWPTRTLHRLEGA
Mflv_2862|M.gilvum_PYR-GCK --------------------------------AHALARPSYKRLFDHP--
MSMEG_6231|M.smegmatis_MC2_155 ----------------------------------PAPLHLLRLATMLPLA
MLBr_01723|M.leprae_Br4923 TFEPKVLETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLGWG
TH_2189|M.thermoresistible__bu TFEPSDLERMARNAGAVEVATASEEFTAAMLGWPVRTFEAAVPPGKLGWN
Mb3862c|M.bovis_AF2122/97 TYTPIAPADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA---------
Rv3832c|M.tuberculosis_H37Rv TYTPIAPADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA---------
MAV_0196|M.avium_104 TYNPIAPKDLPGRLAAAGFADIHADARGGRQRWRAVKPID----------
MAB_2704|M.abscessus_ATCC_1997 TYNPVPTTSLPDRLRAAGFTDIEHHLDGGNQRWRAVKAA-----------
MUL_1534|M.ulcerans_Agy99 TCNPIPPTDLPDRLRAAGFHDVEVEVQAGRQRWRAQKPKA----------
Mvan_2318|M.vanbaalenii_PYR-1 TYNPVDPQTLPGRLEAAGFTDVEVQTN--EFGWSAVAHRA----------
MMAR_1415|M.marinum_M PHRLIERGELQPVLRQLPLSASRVRQNRLLVRFTAMKQASPS--------
Mflv_2862|M.gilvum_PYR-GCK TEDRFSAEQFSDELAHHGLVVLGSRTRIQGDYLLGVAAKPLPTGCE----
MSMEG_6231|M.smegmatis_MC2_155 PLVPFVHDGVISSLRCYSPSALRALAAHAGVALELRGGLTTPQIAIARRA
. .
MLBr_01723|M.leprae_Br4923 WARFAFTSWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
TH_2189|M.thermoresistible__bu WAKFAFGSWTALSWVDANVWRRVMPKGWFYNVMVTGVKPS
Mb3862c|M.bovis_AF2122/97 ----------------------------------------
Rv3832c|M.tuberculosis_H37Rv ----------------------------------------
MAV_0196|M.avium_104 ----------------------------------------
MAB_2704|M.abscessus_ATCC_1997 ----------------------------------------
MUL_1534|M.ulcerans_Agy99 ----------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 ----------------------------------------
MMAR_1415|M.marinum_M ----------------------------------------
Mflv_2862|M.gilvum_PYR-GCK ----------------------------------------
MSMEG_6231|M.smegmatis_MC2_155 ----------------------------------------