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LYPTMSGVEIESYRDRFVRHLSQTVPGRKEFVVAEARGCTVTTADGRSYLDMTSGIGVANVGHCHPRVVE AIQAQAARYAHVNVYGRFVVPEQVELVERLTGAAGAGFDMAYLTSSGAESTECAMKLARKHTGRPKFVAF ERAYHGRTLGALSVSWREEWRAPFEPLLDEVMFVPYDSLTAAAAAVDDRTAAVIVEPIQGEGGIRVPSDD FLPGLRELCDATGALLIVDEVQGGMGRSGRWFAHQHTDVRPDIITMAKAVGGGLPLGAVLASAELFATFV DPPLSHLTTMGGNPVACAAGIAAFDVIADGLLDRVVEAGEYLRTGLAALCDEFAGLLVDVRGRGLWCAIE LSVDANPVVARMQQLGVLVGSVLNQSGTVRIMPPLVISDAEIDTFVGVLRTVLGEVAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3146 | - | - | 100% (408) | aminotransferase class-III |
| M. vanbaalenii PYR-1 | Mvan_3311 | argD | 8e-74 | 42.82% (383) | acetylornithine aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_1287 | - | 7e-55 | 37.82% (386) | ornithine aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 3e-71 | 41.78% (383) | acetylornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_3527 | argD | 9e-72 | 41.78% (383) | acetylornithine aminotransferase |
| M. tuberculosis H37Rv | Rv1655 | argD | 3e-71 | 41.78% (383) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_01409 | argD | 5e-70 | 39.95% (383) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_2339 | argD | 2e-67 | 40.15% (391) | acetylornithine aminotransferase |
| M. marinum M | MMAR_2465 | argD | 6e-69 | 40.78% (385) | acetylornithine aminotransferase ArgD |
| M. avium 104 | MAV_3115 | argD | 6e-72 | 39.85% (399) | acetylornithine aminotransferase |
| M. smegmatis MC2 155 | MSMEG_3773 | argD | 9e-71 | 41.93% (384) | acetylornithine aminotransferase |
| M. thermoresistible (build 8) | TH_3529 | - | 9e-72 | 42.37% (380) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1647 | argD | 4e-69 | 41.04% (385) | acetylornithine aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3773|M.smegmatis_MC2_155 ----------MTLQSRWEAVMMNNY-GTPPLSLVSGEGAVVTDADGREYL
TH_3529|M.thermoresistible__bu ---VSGSKGRHTLLDRWQGVMMNNY-GTPPLALVSGDGAVVTDADGKSYL
Mb1683|M.bovis_AF2122/97 --MTGASTTTATMRQRWQAVMMNNY-GTPPIALASGDGAVVTDVDGRTYI
Rv1655|M.tuberculosis_H37Rv --MTGASTTTATMRQRWQAVMMNNY-GTPPIALASGDGAVVTDVDGRTYI
MLBr_01409|M.leprae_Br4923 --MTPTQTNTATMQQRWETVMMNNY-GTPPIVLASGNGAVVTDVDSNTYL
MMAR_2465|M.marinum_M ------MTHTEDTRARWEAVMMNNY-GTPPVALASGEGAVVTDVDGKNYV
MUL_1647|M.ulcerans_Agy99 ------MTHTEDTRARWEAVMMNNY-GTPPVALASGEGAVVTDVDGKNYV
MAV_3115|M.avium_104 -----MVTNTDALRRRWEAVMMHNY-GTPPVALASGEGAVVTDVDGNTYL
Mflv_3527|M.gilvum_PYR-GCK ----MTGEHRPGLLDRWSAVMMNNY-GTPPLALASGQGAVVTDADGKSYI
MAB_2339|M.abscessus_ATCC_1997 --MTEAPDSTSRAQQRWEHVMMNNY-GTPPIVLAEGEGAVVTDVDGKRYL
Mvan_3146|M.vanbaalenii_PYR-1 MYPTMSGVEIESYRDRFVRHLSQTVPGRKEFVVAEARGCTVTTADGRSYL
*: : :. * . :... *..** .*.. *:
MSMEG_3773|M.smegmatis_MC2_155 DLLGGIAVNLLGHRHPAVIEAVTTQLDTLGHT--SNLYATEPGIALAEAL
TH_3529|M.thermoresistible__bu DLLGGIAVNILGHRHPAVIEAVTRQLNTLGHT--SNLYATEPGVALAEAL
Mb1683|M.bovis_AF2122/97 DLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHT--SNLYATEPGIALAEEL
Rv1655|M.tuberculosis_H37Rv DLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHT--SNLYATEPGIALAEEL
MLBr_01409|M.leprae_Br4923 DLLGGIAVNVLGHRHPAVIEAVTHQITTLGHT--SNLYATEPSITLAEEL
MMAR_2465|M.marinum_M DLLGGIAVNILGHRHPAVIEAVTQQMSTLGHT--SNLYATEPTIALAEEL
MUL_1647|M.ulcerans_Agy99 DLLGGIAVNILGHRHPAVIEAVTQQMSTLGHT--SNLYATEPTNALAEEL
MAV_3115|M.avium_104 DLLGGIAVNVLGHRHPAIIEAVTKQLSTLGHT--SNLYATEPSLALAEEL
Mflv_3527|M.gilvum_PYR-GCK DLLGGIAVNVLGHRHPAVIEAVTRQMNTLGHT--SNLYATEPGVALAEAL
MAB_2339|M.abscessus_ATCC_1997 DLLGGIAVNVLGHRNQSVIDAVTQQLSTLGHT--SNLYATGPAIELSEAL
Mvan_3146|M.vanbaalenii_PYR-1 DMTSGIGVANVGHCHPRVVEAIQAQAARYAHVNVYGRFVVPEQVELVERL
*: .**.* :** : :::*: * .*. . :.. * * *
MSMEG_3773|M.smegmatis_MC2_155 VGQLGTQAR----------------VFFCNSGTEANEVAFKITR-LTGKT
TH_3529|M.thermoresistible__bu VGHLGAPAR----------------VFFCNSGAEANEVAFKISR-LTGRT
Mb1683|M.bovis_AF2122/97 VALLGADQR--------------TRVFFCNSGAEANEAAFKLSR-LTGRT
Rv1655|M.tuberculosis_H37Rv VALLGADQR--------------TRVFFCNSGAEANEAAFKLSR-LTGRT
MLBr_01409|M.leprae_Br4923 VALLGADTQ--------------TRVFFCNSGTEANELAFKLSR-LTGRT
MMAR_2465|M.marinum_M VTLLGAEAP--------------ARVFFCNSGTEANEAAFKLSR-LTGRT
MUL_1647|M.ulcerans_Agy99 VTLLGAEAP--------------ARVFFCNSGTEANEAAFKLSR-LTGRT
MAV_3115|M.avium_104 VALLGAGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKLSR-LTGRT
Mflv_3527|M.gilvum_PYR-GCK VDLLGVPAK----------------VFFCNSGTEANEVAFKITR-LTGRT
MAB_2339|M.abscessus_ATCC_1997 VARLGVPGR----------------VFLCNSGTEANEAAFKLTR-LTGRT
Mvan_3146|M.vanbaalenii_PYR-1 TGAAGAGFD---------------MAYLTSSGAESTECAMKLARKHTGRP
. *. .:: .**:*:.* *:*::* **:.
MSMEG_3773|M.smegmatis_MC2_155 KIVAAEGAFHGRTMGSLALTGQPSKQAPFEPLPGNVMHVPYGDVAALEAA
TH_3529|M.thermoresistible__bu KVVAAEGGFHGRTMGALALTGQPSKREPFEPLPGDVIHVPYGDAGALERA
Mb1683|M.bovis_AF2122/97 KLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAA
Rv1655|M.tuberculosis_H37Rv KLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAA
MLBr_01409|M.leprae_Br4923 KLVAAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYGQVDALAAA
MMAR_2465|M.marinum_M KLVAAQEGFHGRTMGSLALTGQPAKQAPFEPLPGYVTHVPYGDIDALAAA
MUL_1647|M.ulcerans_Agy99 KLVAAQEGFHGRTMGSLALTGQPAKQAPFEPLPGYVTHVPYGDIDALAAA
MAV_3115|M.avium_104 KLVAAQEAFHGRTMGSLALTGQPSKQAPFAPLPGDVTHVPYGDTEALAAA
Mflv_3527|M.gilvum_PYR-GCK KLVAAQGAFHGRTMGSLALTGQPAKQAPFEPLPGDVTHVPYGDVDALRAV
MAB_2339|M.abscessus_ATCC_1997 KVVAAEGAFHGRTMGSLALTGQPAKQAPFEPLPAGVLHVPYGDLAAIEAA
Mvan_3146|M.vanbaalenii_PYR-1 KFVAFERAYHGRTLGALSVSWREEWRAPFEPLLDEVMFVPYDSLTAAAAA
*.** . .:****:*:*::: : : .* ** * .* *.. * .
MSMEG_3773|M.smegmatis_MC2_155 VDDQTAAVFLEPIMGEGGVVVPPAGYLVAAREITSKHGALLVLDEVQTGV
TH_3529|M.thermoresistible__bu VDDTTAAVFLEPIMGEGGVVVPPAGYLAAAREVTARHGALLVLDEVQTGI
Mb1683|M.bovis_AF2122/97 VDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGM
Rv1655|M.tuberculosis_H37Rv VDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGM
MLBr_01409|M.leprae_Br4923 VDNDTAAVFLEPIMGESGVIVPPEGYLAAARDITTRHGALLVIDEVQTGI
MMAR_2465|M.marinum_M VDDETAAVFLEPIMGESGVVVPPEGYLLAAREITARHGALLVLDEVQTGI
MUL_1647|M.ulcerans_Agy99 VDDETAAVFLEPIMGESGVVVPPEGYLLAAREITARHGALLVLDEVQTGI
MAV_3115|M.avium_104 VDDGTAAVFLEPIMGESGVVVPPEGYLAAARDITARHGALLVLDEVQTGM
Mflv_3527|M.gilvum_PYR-GCK VDSETAAVFLEPIMGEGGVVVPPAGYLVAAREITAEHGALLILDEVQTGV
MAB_2339|M.abscessus_ATCC_1997 VDGDTAAVFLEPIMGEGGVVVPPEGYLAGVREITARHGALLVLDEVQTGI
Mvan_3146|M.vanbaalenii_PYR-1 VDDRTAAVIVEPIQGEGGIRVPSDDFLPGLRELCDATGALLIVDEVQGGM
**. ****::*** **.*: **. .:* . *:: ****::**** *:
MSMEG_3773|M.smegmatis_MC2_155 GRTGAFFAHQHDGIVPDVVTMAKGLGGGLPIGACLAVGA-TGDLLTPGL-
TH_3529|M.thermoresistible__bu GRTGTFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGP-AGDLLTPGM-
Mb1683|M.bovis_AF2122/97 GRTGAFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGP-AAELLTPGL-
Rv1655|M.tuberculosis_H37Rv GRTGAFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGP-AAELLTPGL-
MLBr_01409|M.leprae_Br4923 GRTGAFFAHQHDSITPDVVTLAKGLGGGLPIGAFLATGP-AAELLTLGL-
MMAR_2465|M.marinum_M GRTGAFYAHQHDGITPDVVTLAKGLGGGLPIGACLAIGP-AAELLTPGL-
MUL_1647|M.ulcerans_Agy99 GRTGAFYAHQHDGITPDVVTLAKGLGGGLPIGACLAIGP-AAELLTPGL-
MAV_3115|M.avium_104 GRTGTFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGP-AADLLTPGL-
Mflv_3527|M.gilvum_PYR-GCK GRTGAFFAHRHDGITPDVVTLAKGLGGGLPIGACLAIGD-TAELLTPGL-
MAB_2339|M.abscessus_ATCC_1997 GRTGTFFAHQQAGITPDVVTLAKGLGGGLPIGACIATGA-AADLLTPGM-
Mvan_3146|M.vanbaalenii_PYR-1 GRSGRWFAHQHTDVRPDIITMAKAVGGGLPLGAVLASAELFATFVDPPLS
**:* ::**:: .: **::*:**.:*****:** :* . . :: :
MSMEG_3773|M.smegmatis_MC2_155 HGSTFGGNPVCTAAGLAVLKTLAAEDLVARAGVLGKTLSHGIEELG---H
TH_3529|M.thermoresistible__bu HGSTFGGNPVCTAAAVAVLGALAEGDLINRADVLGKKLSHGIEELR---H
Mb1683|M.bovis_AF2122/97 HGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALG---H
Rv1655|M.tuberculosis_H37Rv HGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALG---H
MLBr_01409|M.leprae_Br4923 HGSTFGGNPVCTAAALAVLRVLATQGLVRRAEVLGDSMRIGIESLS---H
MMAR_2465|M.marinum_M HGSTFGGNPVCAAAALAVLRVVASEGLVRRAETLGKTFKQGVESLS---H
MUL_1647|M.ulcerans_Agy99 HGSTFGGNPVCAAAALAVLRVVASEGLVCRAETLGKTFKQGVESLS---H
MAV_3115|M.avium_104 HGSTFGGNPVCAAAALAVLRVLASENLVRHAEVLGKSLHQGIEGLG---H
Mflv_3527|M.gilvum_PYR-GCK HGSTFGGNPVCTAAALAVLKVLADDGLVERADILGKTIAHGIEALN---H
MAB_2339|M.abscessus_ATCC_1997 HGSTFGGNPVCVAAALAVLRVLDEQDLVDHAAAAGKSLSHSVEELN---H
Mvan_3146|M.vanbaalenii_PYR-1 HLTTMGGNPVACAAGIAAFDVIAD-GLLDRVVEAGEYLRTGLAALCDEFA
* :*:*****. **.:*.: .: .*: :. *. : .: *
MSMEG_3773|M.smegmatis_MC2_155 PLVDKVRGKGLLQGIVLTVPSAKAVETAARDAGFLVNAAAP--EVVRLAP
TH_3529|M.thermoresistible__bu PLVDHVRGRGLLCGVVLNAPQAKAAEAAARDAGFLVNAAAP--EVIRLAP
Mb1683|M.bovis_AF2122/97 PLIDHVRGRGLLLGIALTAPHAKDAEATARDAGYLVNAAAP--DVIRLAP
Rv1655|M.tuberculosis_H37Rv PLIDHVRGRGLLLGIALTAPHAKDAEATARDAGYLVNAAAP--DVIRLAP
MLBr_01409|M.leprae_Br4923 PLIDQVRGRGLLLGIVLTAPRAKDIEKAARDAGFLVNATAP--EVIRLAP
MMAR_2465|M.marinum_M PLIDHVRGRGLLLGIVLAGPHAKAAEVAAREAGYLVNGAAP--NVVRLAP
MUL_1647|M.ulcerans_Agy99 PLIDHVRGRGLLLGIVLAGPHAKAAEVAAREVGYLVNGAAP--NVVRLAP
MAV_3115|M.avium_104 PLVDHVRGRGLLCGVVLTAPRAKDAEAAAREAGFLVNAAAP--GVIRLAP
Mflv_3527|M.gilvum_PYR-GCK PLVDHVRGLGLLRGIVLTADAAKSVEAEARDAGFLVNAAAA--DVIRLAP
MAB_2339|M.abscessus_ATCC_1997 PLVDRVRGAGLLLGIVLTEQRAKAAETAAREAGFLVNAAAP--DVLRLAP
Mvan_3146|M.vanbaalenii_PYR-1 GLLVDVRGRGLWCAIELSVD-ANPVVARMQQLGVLVGSVLNQSGTVRIMP
*: *** ** .: * *: :: * **... .:*: *
MSMEG_3773|M.smegmatis_MC2_155 PLIITEGQIEAFITALPAVLDTAAEDS----
TH_3529|M.thermoresistible__bu PLIITETQIDEFLAALPGVLDTAKEAS----
Mb1683|M.bovis_AF2122/97 PLIIAEAQLDGFVAALPAILDRAVGAP----
Rv1655|M.tuberculosis_H37Rv PLIIAEAQLDGFVAALPAILDRAVGAP----
MLBr_01409|M.leprae_Br4923 PLIITESQIDSFITALPGILDASIAELGKKA
MMAR_2465|M.marinum_M PLVITEPQLEGFVAALPGILDTAGASA----
MUL_1647|M.ulcerans_Agy99 PLVITEPQLEGFVAALPGILDNAGASA----
MAV_3115|M.avium_104 PLIVTEAQIDGFIAALPGILDRAAA------
Mflv_3527|M.gilvum_PYR-GCK PLVITDAEVESFLAALPRILDKAAQS-----
MAB_2339|M.abscessus_ATCC_1997 PLIITDEQIGEFVTALPGILDTAAEQEQA--
Mvan_3146|M.vanbaalenii_PYR-1 PLVISDAEIDTFVGVLRTVLGEVAS------
**:::: :: *: .* :*.