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ARHAKKSDRSMAIRTYLTAGLTAGVTGAALAGVGTLLLADGDVSGPAQIEVQLVSNEEDILWLSLNGGSD RRSAAQSAVVQQSSANPALRPMIGDGGWLIGNGLDAADDCQGDACNGGDGGILWGNGGNGAHGGTGGDGG FWFGHGGNGGDGDAVLDANGNVVRAATAGGAGGKGGYMFGNGGAGGKGGDAVYQNGVKKNGALAGGRGGD SGYLLGNGGNGGAGGSDSNNLNVADDPATTNVNESAQNNAAGGAGGAGGVGGILNGNGGHGGDGGSADSA NGNATGGSGGRGGLAHSNAGGTGGNGGNGGDAEADDAGKTAKGGNGGAGGTSGTGQGGSGGNGGNAVGDD AHAVGGSGGAGGGVRLGTGGDGGDGGDAVSEDGNATGGKGGDGGSVDLTGGGGGAGGEGGDADGDEKATG GSGGSGGTGGLGGDGGAGGDGGDAVADDEGGATAGSGGDGGFGGTDGDDGSASDGADAPATD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5240 | - | - | 100% (483) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_2459 | - | 3e-87 | 40.97% (537) | PE_PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_3856 | - | 6e-74 | 42.79% (416) | hypothetical protein Mvan_3856 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3402 | PE_PGRS51 | 9e-79 | 39.74% (541) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_1516 | - | 1e-115 | 50.81% (496) | hypothetical protein Mflv_1516 |
M. tuberculosis H37Rv | Rv0977 | PE_PGRS16 | 1e-77 | 39.65% (512) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 3e-06 | 39.29% (84) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 4e-33 | 33.08% (399) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_0478 | - | 5e-79 | 41.46% (521) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 9e-20 | 42.41% (158) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_3202 | - | 9e-60 | 39.69% (383) | hypothetical protein MSMEG_3202 |
M. thermoresistible (build 8) | TH_4332 | - | 3e-41 | 37.03% (397) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4431 | - | 2e-77 | 42.83% (495) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_5240|M.vanbaalenii_PYR-1 ------------------MARHAKKSDRSMAIRTYLT-AGLTAGVTGAAL Mflv_1516|M.gilvum_PYR-GCK ------------------MARHANTSDRSAAIRRYLG-AGITAGMASAAL Mb3402|M.bovis_AF2122/97 ------------------MSFVVAVPEALAAAASDVANIGSALSAANAAA Rv0977|M.tuberculosis_H37Rv ------------------MSFVVTAPPVLASAASDLGGIASMISEANAMA MMAR_0478|M.marinum_M ------------------MSFVSVIPEQLTAAATNLAGVGSTISTANATA MUL_4431|M.ulcerans_Agy99 ------------------MSYVMAVPELLASAAADLEGIGSALSTANALA TH_4332|M.thermoresistible__bu -----------------------------------------MPFITSGAA MSMEG_3202|M.smegmatis_MC2_155 --------------------MTKHQRLTSAVAASIVATAGVAVSQAPAPA MAB_4284c|M.abscessus_ATCC_199 ----------------------MSIIDFILNLFRDPVEAASYVADPEAAL MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEED MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES Mvan_5240|M.vanbaalenii_PYR-1 AGVGTLLLADGDVSGPAQIEVQLVSNEEDILWLSLNGGSDRRSAAQSAVV Mflv_1516|M.gilvum_PYR-GCK AGVGTALLTDVDASTSTDPRVQLVSNEEELLWLTLDAGSDRAKTDSSSAL Mb3402|M.bovis_AF2122/97 AAGTTGLLAAGADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQALTG Rv0977|M.tuberculosis_H37Rv AVRTTALAPAAADEVSAAIAALFSSYARDYQTLSVQVTAFHVQFAQTLTN MMAR_0478|M.marinum_M AGPTAAALAAGADDVSAAVSSFFGAYARDYQAFSVQVEALHDQFVRAVTS MUL_4431|M.ulcerans_Agy99 LPSTSEILAAGTDEISTAVASLFADHAQDYRTISLEANAFHQQFWRSLSG TH_4332|M.thermoresistible__bu FVGGAAMLLAGPGGVSALEAAGSAPRTVEYEYSLVACDSTLPLMCEAG-- MSMEG_3202|M.smegmatis_MC2_155 STGTPTAHQTPTSTSTPRWLTVTSTPEGAPATPNALYGAILPSTSPGSVT MAB_4284c|M.abscessus_ATCC_199 ANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQN MAV_4827|M.avium_104 AIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA MLBr_01556|M.leprae_Br4923 FGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAP Mvan_5240|M.vanbaalenii_PYR-1 QQSS--------------ANPALRPMIGDGGWLIGNGLD--AADDCQGDA Mflv_1516|M.gilvum_PYR-GCK AQAS--------------ATPALRPIIGPGGWLIGDGLD--AAADCTGEA Mb3402|M.bovis_AF2122/97 AGGSYALTEAAN-----VQQNLLNAINAPTQALLGRPLIGDGAVGTASS- Rv0977|M.tuberculosis_H37Rv AGQLYAVVDVGNGVLLKTEQQVLGVINAPTQTLVGRPLIGDGTHGAPGTG MMAR_0478|M.marinum_M GAASYAGAEAT-----SVQQILLDAINAPTQALLGRPLIGNGANAAPGSG MUL_4431|M.ulcerans_Agy99 AAASYSGAEAANA---SPLQELLNVINQQSTALLGRPLIGNGADGAAP-G TH_4332|M.thermoresistible__bu -----------------------DSVGGLGGASHDRSAFSASALGMASFG MSMEG_3202|M.smegmatis_MC2_155 STGSG-------------IGHREPGISGSPAFTAVRAVRPGSSTARLVFA MAB_4284c|M.abscessus_ATCC_199 YYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGN MAV_4827|M.avium_104 AALRDALAARRIDN----VMLVSAFLAAAALAQNVGGAMGYERTAVLLVE MLBr_01556|M.leprae_Br4923 VQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA Mvan_5240|M.vanbaalenii_PYR-1 CNGGDGGILWGNGGNG--------AHGGTGGDG----------------- Mflv_1516|M.gilvum_PYR-GCK CNGGNGGLLGGNGGDG--------RYGGAGGKA----------------- Mb3402|M.bovis_AF2122/97 PDGQDGGLLFGNGGAGYNSAATPGMAGGNGGNAGLIGNGGTGGSGGAGAA Rv0977|M.tuberculosis_H37Rv QNGGAGGILWGNGGNG--GSGAPGQPGGRGGDAGLFGHGGHGGVGGPGIA MMAR_0478|M.marinum_M ANGGDGGILYGNGGAG-GSG-AAGGNGGAGGAAGLVGNGGAGGAGGNNAA MUL_4431|M.ulcerans_Agy99 QSGDDGGLLFGNGGNG-APGTNQGVAGGNGGSAGLIGNGGAG-------- TH_4332|M.thermoresistible__bu PDWNPGGAFLGLIGPG---------------------------------- MSMEG_3202|M.smegmatis_MC2_155 PKTSTSGTALTVTPIAVGMVGNAKVTVAVDSSGRP--------------- MAB_4284c|M.abscessus_ATCC_199 VDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVG--------------- MAV_4827|M.avium_104 PDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG-----LEK MLBr_01556|M.leprae_Br4923 PHPGHPGMPTGPHPGP--APKPGGRPPRVGNNPFSSAQSVARPIPRPPAP . Mvan_5240|M.vanbaalenii_PYR-1 -------GFWFGHGGNGGDG------DAVLDANGNVVRAATAGGAGGKGG Mflv_1516|M.gilvum_PYR-GCK -------GLYFGDGGNGGDGV-----NAVYGANGALVSAAGQGGRGGDG- Mb3402|M.bovis_AF2122/97 GGAGGSGGWLYGNGGNGGIGGNAIVAGGAGGNGGAG-GAAGLWGSGGSGG Rv0977|M.tuberculosis_H37Rv G-AAGTAGLPGGNGANGGSGG-IGGAGGAGGNGGLLFGNGGAGGQGGSGG MMAR_0478|M.marinum_M GGSGGAGGLLYGNGGAGGIGGTSAGSGGAGGAGGLLFGTGGAGGTGGFGG MUL_4431|M.ulcerans_Agy99 ----GHGGMLFGDGGAG---------GGGGDSPSFVIG-GGAGGNGGNAG TH_4332|M.thermoresistible__bu -------GLLIGDGLNG------------TDAYIDENGVFHEATRGGNGG MSMEG_3202|M.smegmatis_MC2_155 --MIGPGGWLIGNGIEPGQN---------GGLLIGNGADGGPGQKGGNGG MAB_4284c|M.abscessus_ATCC_199 --GSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYT MAV_4827|M.avium_104 LESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAA MLBr_01556|M.leprae_Br4923 RPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGG * . Mvan_5240|M.vanbaalenii_PYR-1 YMFGNGGAGGKGGDAVYQNGVKKNGALAG----------GRGGDSGYLLG Mflv_1516|M.gilvum_PYR-GCK SLFGRGGDGGAGGNDDNTSNFTGTDAPKN----------NATG------G Mb3402|M.bovis_AF2122/97 -QGGNGLTGNDGVNPAPVTNP----ALNG-----AAGDSNIEPQTSVLIG Rv0977|M.tuberculosis_H37Rv -LGGSGGTGGAGMAAGPAGGTGGIGGIGG-----IGGAGGVGGHGSALFG MMAR_0478|M.marinum_M GLMTSGGAGGTGGAGGLLFGTGGSGGAGGGSNAFTAGDGGAGGAGGLLFG MUL_4431|M.ulcerans_Agy99 -LFGNAGAGGAGGAGQQFFFNGGAGGDGG-----SVG----------LIG TH_4332|M.thermoresistible__bu LLWGNGGKGGNGLDAGLYTVPDPDNPGST--------------------- MSMEG_3202|M.smegmatis_MC2_155 FLLGNGGRGGDGLAGVNGGRAGDGGNAG-------------------LLG MAB_4284c|M.abscessus_ATCC_199 NVSGHGSADIDKSVTVVDDHSQRNTTNIN---------DSFNTDRSTNIG MAV_4827|M.avium_104 ANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSA MLBr_01556|M.leprae_Br4923 NYRGGGVGALPGGGSGGFRGRPGGGGHGGGG---RPGQRGGAAGAFGRPG Mvan_5240|M.vanbaalenii_PYR-1 NGGNGGAGGSDS-----NNLNVA---------DDPATTNVNESA------ Mflv_1516|M.gilvum_PYR-GCK RGGNGGR----------SQLGQA---------GDGGAGGQAWSE------ Mb3402|M.bovis_AF2122/97 TQ--GGDGTPG------GAGVNG---------GNGGAGGDANGNPANTSI Rv0977|M.tuberculosis_H37Rv HGGINGDGGTG------GMGGQG---------GAGGNGWAAEGITVGIGE MMAR_0478|M.marinum_M TGGSGGDGGLAPG-AMFGNGGHG---------GTGGAGGTLSGI------ MUL_4431|M.ulcerans_Agy99 NGGAGGDG---------ANGAAG---------GAGGDGGMLSGN------ TH_4332|M.thermoresistible__bu ------------I-QMYFEASDG---------ADGGRGGFLFGN------ MSMEG_3202|M.smegmatis_MC2_155 NGGDGGNSVGGVEGANGGNAGLI---------GNGGKGGDGSPN------ MAB_4284c|M.abscessus_ATCC_199 SGNTTNTEIGSHNQANIGTSTSA---------GGSAAVGGNAGLAG---- MAV_4827|M.avium_104 VGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIA MLBr_01556|M.leprae_Br4923 GAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFA Mvan_5240|M.vanbaalenii_PYR-1 ---QNNAAGG--AGGAGGVGGILNGNGGHGGDGGS-ADSANGNAT-GGSG Mflv_1516|M.gilvum_PYR-GCK ---SGSATGG--AGGTG--GGTNYGKAGSGGDGGSGSAWADGKVGKGGVG Mb3402|M.bovis_AF2122/97 ANAGAGGNGA--AGGDGGANGGAGGAGG-QAASAGSSVGGDG--GNGGAG Rv0977|M.tuberculosis_H37Rv Q-GGQGGDGG--AGGAGGIGGSAGGIGGSQGAGGHGGDGGQG--GAGGSG MMAR_0478|M.marinum_M --GGHGGAGG-LGQVSGGAGGDGGNGGVFFGGGGDGGIGGHGITGSGGSG MUL_4431|M.ulcerans_Agy99 --GGNGGAGGDLNDPAVPTGSQVGGRGGNAGLIGNGGIGGDG--GVAANG TH_4332|M.thermoresistible__bu -------------GGDGGNGGNVGGKNGADPVTATVAADKSVAGGNGGNG MSMEG_3202|M.smegmatis_MC2_155 VISNGAHIANAGRGGNGGNGGLLVGSGGDGGRGGDGDGEGPETAGSHGAD MAB_4284c|M.abscessus_ATCC_199 ---NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA MAV_4827|M.avium_104 LAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVA MLBr_01556|M.leprae_Br4923 EKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPED Mvan_5240|M.vanbaalenii_PYR-1 GRGGLAHSNAGGTGGNGGNGGDAEADDAGKT---AKGGNGG-AGGTSG-- Mflv_1516|M.gilvum_PYR-GCK GNGGGSRADSG-SGGAGGTGGDGWGYEEAD----AQGGNGG-AGGLT--- Mb3402|M.bovis_AF2122/97 GTGT-NGH-AGGAGGAGGQAASAG-SSVG-----GDGGNGG-AGGTGTNG Rv0977|M.tuberculosis_H37Rv GVGG-GGAGAGGDGGAGGIGGTGGNGSIGGAA--GNGGNGG-RGGAGGMA MMAR_0478|M.marinum_M GSGG-SGGFLPGGAGVAGLIGDGGAGGHG-----GSGGSGGGTGGSG--G MUL_4431|M.ulcerans_Agy99 GAGG-QGGLLRGDGGDGGAGGAGRPASFN-----SNGGPGG-NGGNG--G TH_4332|M.thermoresistible__bu GRGG----LLFGLGGNGGNGGWSTTSYLDARG--GNGGNGGLGGVLRPGG MSMEG_3202|M.smegmatis_MC2_155 GGNG-GAGGVFGNGGRGGDGGDANNGTVGTRNGNAAAGKGGNGGSTG--- MAB_4284c|M.abscessus_ATCC_199 GNAG-LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG MAV_4827|M.avium_104 APKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPV MLBr_01556|M.leprae_Br4923 EDRELLEPFDLTYGEDQGD-EDELQVRPPVVTVMGHVDHGKTRLLDTIRK Mvan_5240|M.vanbaalenii_PYR-1 -----TGQGGSGGNGG----------------------NAVGDD------ Mflv_1516|M.gilvum_PYR-GCK --------GGRGGHGG----------------------AAESLN------ Mb3402|M.bovis_AF2122/97 HAGGAGGAGGAGGRGGWLVG-SGGNGGNGGNGAAGGNGAIGGTG-----G Rv0977|M.tuberculosis_H37Rv TAGSDGGNGGGGGNGGVGVGSAGGAGGTGGDGGAAGAGGAPGHGYFQQPA MMAR_0478|M.marinum_M SAGTLLGNGGAGGGGGSGSTTAGGGGSGGDAGALFGNGGAGGAG------ MUL_4431|M.ulcerans_Agy99 SAG-LWGNGGTGGAGG----------------------GPGTQG------ TH_4332|M.thermoresistible__bu LLSLLLPSGAASEPGG---------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -----IGTGGAGGNGG----------------------KATGTN------ MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVL MAV_4827|M.avium_104 PVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSP MLBr_01556|M.leprae_Br4923 ANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGA Mvan_5240|M.vanbaalenii_PYR-1 ----AHAVGGSGGAG------GGVRLGTGGDGGDGGDAVS--EDGNATG- Mflv_1516|M.gilvum_PYR-GCK ----GDATGGNGGNG------GGARV--VGDGGDGGDGGY--GWGGVPD- Mb3402|M.bovis_AF2122/97 AGGVPANQGGNSALGTQPVSGDGGDGGNGGTGGTGGRGGD-GGSGGAGGA Rv0977|M.tuberculosis_H37Rv PQGLPIGTGGTGGEG--GAGGAGGDGGQGDIGFDGGRGGD-GGPGGGGGA MMAR_0478|M.marinum_M --GSGAATGGSGGTG----GSSALLFGTGGVGGVGGSGGDSGGTGGAGGQ MUL_4431|M.ulcerans_Agy99 --SDNSGSGGNGGNG----GNAGLFSGIAGNGGDGGQGGEADRTGGVGGM TH_4332|M.thermoresistible__bu -----LFTGGNGGNG-------GLAIANHWVGITDGVPGP---------- MSMEG_3202|M.smegmatis_MC2_155 -----AAYGGNGGNG-------GSGLAGGGNGGDGGDAQSSSNRARPGQ- MAB_4284c|M.abscessus_ATCC_199 NTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTGV MAV_4827|M.avium_104 PQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPGAGGS MLBr_01556|M.leprae_Br4923 KATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAK . Mvan_5240|M.vanbaalenii_PYR-1 ---------------GKGGDGGSVDLTGGGGGAGGE-------------- Mflv_1516|M.gilvum_PYR-GCK ---------------EEGDPVGTGNGKGGNGGAGGN-------------- Mb3402|M.bovis_AF2122/97 SG-------WLMGNGGNGGNGGTGG-SGGVGGNGGIGGDG---------A Rv0977|M.tuberculosis_H37Rv GGDGSGTFNAQANNGGDGGAGGVGG-AGGTGGTGGVGADGGRGGDSGRGG MMAR_0478|M.marinum_M GG-------AMFGNGGAGGGGGDGINVGGKGGAGGAAATLFGSG----GT MUL_4431|M.ulcerans_Agy99 G-----------GAGGAAGLFGTGG-TRGTGGTGGAANPFGAAG----GS TH_4332|M.thermoresistible__bu -----------------DDDAVSSSAYGGHGGHGAGP------------- MSMEG_3202|M.smegmatis_MC2_155 ---------------GGQAGRGGFGRDGKTGNPGNAT------------- MAB_4284c|M.abscessus_ATCC_199 GVG-------SHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG MAV_4827|M.avium_104 GG-----------SGGGHVPTPGTGGPGGTGGSGGGHVPTPGAG------ MLBr_01556|M.leprae_Br4923 IRG------QLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTAD Mvan_5240|M.vanbaalenii_PYR-1 --GGDADGDEKATGGSGGSG-------GTGGLGGDGGAGGDGGDAVADDE Mflv_1516|M.gilvum_PYR-GCK --GGVAVGN----GGNGGIG-------GDGYNETGGTKTPVAGKGGPGGA Mb3402|M.bovis_AF2122/97 GGGNATSTSSIPFDAHGGNGGA----GGDAGHGGTGGDGGDGGHAGTGGR Rv0977|M.tuberculosis_H37Rv DGGNAGHGGAAQFSGRGAYGGE----GGSGGAGGNAGGAGTGGTAGSGGA MMAR_0478|M.marinum_M GGDGGNAGAGVTFGGAGGEGGAAALLGGNGGSGGHGGIGNVGGKGGAGAA MUL_4431|M.ulcerans_Agy99 GGSGGAGGLLRGMGGAGGTG-------GTGGTGGAAGLIGVGGSGGAGGD TH_4332|M.thermoresistible__bu -GSGGNGGSAVANSLGNAIA-------GNGGDAGRFVLIGPGGNGGNGGT MSMEG_3202|M.smegmatis_MC2_155 --DRSATRENVSNRVTGRSTPT-----RSADKAGSRTSSSSESNSESNSE MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGGSGSVGGS--TAVGGGAHTGVGGGVNTGVGVGSHVG MAV_4827|M.avium_104 -TPGGSGGGHLPFPGAGSTPGG-----SGGGHLPTPGAGTPGGGLGGFGG MLBr_01556|M.leprae_Br4923 AALDLRANSGMEAQGVAIEAHLD---RGRGPVATVLVQRGTLRIGDSVVA . Mvan_5240|M.vanbaalenii_PYR-1 GGATAGSGGDGGFGGT-----------DGDDGSASDGADAPATD------ Mflv_1516|M.gilvum_PYR-GCK GGAIGSDGDAGADGET-----------ETSSGSSGSAGSADSDD------ Mb3402|M.bovis_AF2122/97 GGLLAGQHANSGNGGG-----GGTGGAGGTHGTPGSGNAGGTG------- Rv0977|M.tuberculosis_H37Rv GG-FGGNGADGGNGGN-----GGNGGFGGINGTFGTNGAGGTGGLGTLLG MMAR_0478|M.marinum_M GAMLLGNGGDGGDGGNSLASLAGAGGAAGNAGLIGSGGTGGAGGQ----- MUL_4431|M.ulcerans_Agy99 G-LLFSDAGVGGSGG--------TGGAGG--WFYGTGGGGGAGG------ TH_4332|M.thermoresistible__bu GLXXXPRPRRRRNHRR------------TRRRPNGRRPRPPPGR------ MSMEG_3202|M.smegmatis_MC2_155 SSSKTSSKAGGTKSSD----------TKSGGGAAGTGSDSKDSE------ MAB_4284c|M.abscessus_ATCC_199 GGISESLGGSGSVGGS----TAVGGGAHTSAINDALGGSGSVGGSTAVGG MAV_4827|M.avium_104 GHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK------ MLBr_01556|M.leprae_Br4923 GDAYGRVRRMVDEHGVD----IEAALPSSPVQVIGFTSVPGAGDNFLVVD . . Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------- Mb3402|M.bovis_AF2122/97 -----------TGNADST-----------------------NGG------ Rv0977|M.tuberculosis_H37Rv GHNGNIGLNGATGGIGSTTLTNATVPLQLVNTTEPVVFISLNGGQMVPVL MMAR_0478|M.marinum_M ---------SFSGTGG-------------------------KGG------ MUL_4431|M.ulcerans_Agy99 ----------VSATTG-------------------------NGG------ TH_4332|M.thermoresistible__bu -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GAHTSAINESMNSSINAS----------------------HSSSMNESFG MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 EDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGD Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------- Mb3402|M.bovis_AF2122/97 --PGSDGLGGDAFNGSR--------GTDGNPG------------------ Rv0977|M.tuberculosis_H37Rv LDTGSTGLVMDSQFLTQNFGPVIGTGTAGYAGGLTYNYNTYSTTVDFGNG MMAR_0478|M.marinum_M -DGGSALLIGDGGNGGNG-------GTGATAGVGGT-------------- MUL_4431|M.ulcerans_Agy99 -NGGNAGLIGDGGAG----------GAGAIPGAG---------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 NAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIG Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------- Mb3402|M.bovis_AF2122/97 -------------------------------------------------- Rv0977|M.tuberculosis_H37Rv LLTLPTSVNVVTSSSPGTLGNFLSRSGAVGVLGIGPNNGFPGTSSIVTAM MMAR_0478|M.marinum_M ---------------AGTGGFLFGLDGMNGSP------------------ MUL_4431|M.ulcerans_Agy99 ----------------GAGGRIFGALGLPG-------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 FNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQL Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------- Mb3402|M.bovis_AF2122/97 -------------------------------------------------- Rv0977|M.tuberculosis_H37Rv PGLLNNGVLIDESAGILQFGPNTLTGGITISGAPISTVAVQIDNGPLQQA MMAR_0478|M.marinum_M -------------------------------------------------- MUL_4431|M.ulcerans_Agy99 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 GRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTS Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------- Mb3402|M.bovis_AF2122/97 -------------------------------------------------- Rv0977|M.tuberculosis_H37Rv PVMFDSGGINGTIPSALASLPSGGFVPAGTTISVYTSDGQTLLYSYTTTA MMAR_0478|M.marinum_M -------------------------------------------------- MUL_4431|M.ulcerans_Agy99 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 LRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA------- Mvan_5240|M.vanbaalenii_PYR-1 --------------------------------------- Mflv_1516|M.gilvum_PYR-GCK --------------------------------------- Mb3402|M.bovis_AF2122/97 --------------------------------------- Rv0977|M.tuberculosis_H37Rv TNTPFVTSGGVMNTGHVPFAQQPIYVSYSPTAIGTTTFN MMAR_0478|M.marinum_M --------------------------------------- MUL_4431|M.ulcerans_Agy99 --------------------------------------- TH_4332|M.thermoresistible__bu --------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 --------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------- MAV_4827|M.avium_104 --------------------------------------- MLBr_01556|M.leprae_Br4923 ---------------------------------------