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M. vanbaalenii PYR-1 Mvan_2459 (-)

annotation: PE_PGRS family protein
coordinates: 2611869 - 2613542
length: 557

MARRLSKTVDASDGNILRCAGAGPRYWIAAGTGGAAVMGVGLLAGLCSETPATVERPVRLASFDSLIVAN
SPVPEDIWLFGAAGSPKRDRSGPATAAAPGVAAVRPMIGPGGWLIGDGADAVEDCEGSACDGRNGGVLWG
NGGNGARGGKGGNAGMFGGNGGRGGDGYLPGQDGGDGGDAGIFASTGNGGDGGHGADGGPGTRGGHGGAG
GDAGRLHGNGGAGGNGGNGGVGVDSVNPSAGGSAAAGSPNYLGTTGFPYTNVVVDNAITGNAGGRGKDAA
AGTNQSGGAGGTGQGVTGFLALPHRYNISGDGGDGGNGAGGGLGGDGGDAGLAQEATPTAAAFGGRGGNG
GTGGTGARGGDGGAGGSVDIGQTVGFGGHGGNGGAGGTGAAGATGAAGGNGGAGGRSGSRTGNGGAGGAA
GNGGSGGNGATGGDGGSGGVGGADVSDPGSGPVTAGTGGNGGSGGAGGAGGDGGAGGLGGKGGAGSSEGS
AGADAANGATGVGGSGGAGGRGGTGGASGDGASGGSGGAGKPGTGPTGSKGGAGGSGGSGGSGGQAD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2459--100% (557)PE_PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-2e-9541.00% (539) triple helix repeat-containing collagen
M. vanbaalenii PYR-1Mvan_5240-9e-8540.60% (532) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3543PE_PGRS571e-10245.24% (515) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-10141.32% (547) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS541e-10044.74% (523) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB7e-0935.77% (137) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_4284c-9e-4233.72% (433) hypothetical protein MAB_4284c
M. marinum MMMAR_4270-1e-9844.47% (515) PE-PGRS family protein
M. avium 104MAV_4827-1e-2344.03% (159) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-7335.71% (644) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-4e-4435.84% (385) PUTATIVE -
M. ulcerans Agy99MUL_0740-7e-9442.80% (500) PE-PGRS family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3543|M.bovis_AF2122/97            ----------------------------------MSFVLIAPEFVTAAAG
Rv3508|M.tuberculosis_H37Rv         ----------------------------------MSFVLIAPEFVTAAAG
MUL_0740|M.ulcerans_Agy99           ----------------------------------MSFVSVSPELVIDGAA
MMAR_4270|M.marinum_M               ----------------------------------MSFVFAVPETMAAVTS
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mflv_5091|M.gilvum_PYR-GCK          ----MVTFGGGATPTPTSLGAAAVDLSGTSCG---LICNGQDGTGQNGGI
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------MSIIDFILNLFRDPVEAASYVADP
MAV_4827|M.avium_104                ---------------------MNIVLGVSMAPSSIQMVVLEGEYADGATV
MLBr_01556|M.leprae_Br4923          ------------------------------MAGKARVHELAKELGVTSKE
                                                                                      

Mb3543|M.bovis_AF2122/97            DLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFG-----LE
Rv3508|M.tuberculosis_H37Rv         DLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFG-----LE
MUL_0740|M.ulcerans_Agy99           ALTQIGSSIDEANAAAG-ATRAVLPPGVDEVSVALAALFVAHG-----RE
MMAR_4270|M.marinum_M               ELATIGSNLEMANAAAALPTTGLLAAGADEVSAAIAALFDEHA-----LG
Mvan_2459|M.vanbaalenii_PYR-1       ----MARRLSKTVDASDG---NILRCAG----AGPRYWIAAGT-------
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mflv_5091|M.gilvum_PYR-GCK          LFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGGNAG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      EAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGN------P
MAV_4827|M.avium_104                EEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQ
MLBr_01556|M.leprae_Br4923          VLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQ
                                                                                      

Mb3543|M.bovis_AF2122/97            YQAISAQVAAYHQRFVQALSTGAGAYASAEAA---------AAEQIVLGV
Rv3508|M.tuberculosis_H37Rv         YQAISAQVAAYHQRFVQALSTGAGAYASAEAA---------AAEQIVLGV
MUL_0740|M.ulcerans_Agy99           YESLSAQVALFHRRFVQMLAAASGGYAEAEAANISAVAGLETVEQCVLDV
MMAR_4270|M.marinum_M               YQTISAQASAFHARFMSALNTGAGAYAAAEAANSSP---LQALQDLTLNA
Mvan_2459|M.vanbaalenii_PYR-1       ----GGAAVMGVGLLAGLCSETPATVERPVR----------LASFDSLIV
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGL---LSVVTLGTTLI
Mflv_5091|M.gilvum_PYR-GCK          AFALFGNGGNGGNGGVGVVGATGAVGAPGVAGATG------ATGVTSGVV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      IHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIAS
MAV_4827|M.avium_104                LEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGG---AMGYERTAVLL
MLBr_01556|M.leprae_Br4923          AKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHS------AAVVPIVA
                                                                                      

Mb3543|M.bovis_AF2122/97            INAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGNG------------
Rv3508|M.tuberculosis_H37Rv         INAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGNG------------
MUL_0740|M.ulcerans_Agy99           INAPTQALFGWSLIGNGTDGAPGSGQAGGNGGLLWGNG------------
MMAR_4270|M.marinum_M               INAPAQSLFGRPLIGDGAN-ATTPGGNGGAGGILWGNG------------
Mvan_2459|M.vanbaalenii_PYR-1       ANSPVP----EDIWLFGAAGSPKRDRSGPATAAAPG--------------
MSMEG_0868|M.smegmatis_MC2_155      PNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAV
Mflv_5091|M.gilvum_PYR-GCK          GGNGEDAVGYGATGAAGAAGAAGAAGAAGAVGSAGAAG------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG------------
MAV_4827|M.avium_104                VEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG--------------
MLBr_01556|M.leprae_Br4923          GEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPG----------
                                                                                      

Mb3543|M.bovis_AF2122/97            ------------------------GAGAAGAPGQAGGPGGPAGLWGNGGP
Rv3508|M.tuberculosis_H37Rv         ------------------------GAGAAGAPGQAGGPGGPAGLWGNGGP
MUL_0740|M.ulcerans_Agy99           ------------------------GNGGSGGVGQAGGAGGSAGLLGHGGA
MMAR_4270|M.marinum_M               ------------------------GAGATGAAGQTGGNGGAAGFIGNGGA
Mvan_2459|M.vanbaalenii_PYR-1       ------------------------VAAVRPMIG------PGGWLIGDGAD
MSMEG_0868|M.smegmatis_MC2_155      LDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN
Mflv_5091|M.gilvum_PYR-GCK          ------------------------EAGETGTWGNAGLPGKAGDAGGAGAV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------DGAVAVGGSNSGPIASGQGSTAVNGDV
MAV_4827|M.avium_104                -----------------------QLSAMVAGLEKLESLPGGLLLVGSGVD
MLBr_01556|M.leprae_Br4923          ----------------------HPGMPTGPHPGPAPKPGGRPPRVGNNPF
                                                                                      

Mb3543|M.bovis_AF2122/97            GGAGGSGGGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGG
Rv3508|M.tuberculosis_H37Rv         GGAGGSGGGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGG
MUL_0740|M.ulcerans_Agy99           GGAGG-----------------VSGVSAVG----ATGGAGGNGGWLYGNG
MMAR_4270|M.marinum_M               GGAGGAG---------------------------ATGGVGGSGGMLFGNG
Mvan_2459|M.vanbaalenii_PYR-1       AVED-----------------------CEGSAC---DGRNGG--VLWGNG
MSMEG_0868|M.smegmatis_MC2_155      GTADNPNGGTGGL------LFGDGGHGYDGSAAGL-AGGNGGNAGLFGNG
Mflv_5091|M.gilvum_PYR-GCK          GAAG-----------------AAGTVGTAGATGGTGTGANGGAGGVGGVG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      RDSNIIN----------------ADHGSNVGVDQSQTRVGGDYTNVSGHG
MAV_4827|M.avium_104                VAPLK---------------------QVLQTTTFLDVSVAEEPETALARG
MLBr_01556|M.leprae_Br4923          SSAQSVAR--------------PIPRPPAPRPSASPSSMSPRPGGAVGGG
                                                                                      

Mb3543|M.bovis_AF2122/97            GAGGVGGAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHG
Rv3508|M.tuberculosis_H37Rv         GAGGVGGAGGGTGGAGGRAELLFGAGGAG---GAGTDGGPGATGGTGGHG
MUL_0740|M.ulcerans_Agy99           GAGGLGGQGVLIG----------------------------------GNG
MMAR_4270|M.marinum_M               GAGGNGGTAMVVGG-------------------------------TGGNG
Mvan_2459|M.vanbaalenii_PYR-1       GNGAR--------------------------------------------G
MSMEG_0868|M.smegmatis_MC2_155      GNGGVGWA--------------------------------------GLDG
Mflv_5091|M.gilvum_PYR-GCK          GTGAAGAA--------------------------------------GGAG
TH_3810|M.thermoresistible__bu      ---------------------------------------------VDGDG
MAB_4284c|M.abscessus_ATCC_199      SADIDKSVTVVDD---------------------------------HSQR
MAV_4827|M.avium_104                AALAAAN-----------------------------------------AP
MLBr_01556|M.leprae_Br4923          GPRPPRTGVPR-----------------------------------PGGG
                                                                                      

Mb3543|M.bovis_AF2122/97            GVGGDGGWLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGG
Rv3508|M.tuberculosis_H37Rv         GVGGDGGWLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGG
MUL_0740|M.ulcerans_Agy99           GAGGAARFFGAGGTGGAGGLG-----------LGDTGGIGGIGGNAGA--
MMAR_4270|M.marinum_M               GAGGSAGLFGAGGAGGQGGQG----------AQGPDAVNPGPVSPTGQ--
Mvan_2459|M.vanbaalenii_PYR-1       GKGGNAGMFG--GNGGRGGDG---------YLPGQDGGDGGDAG------
MSMEG_0868|M.smegmatis_MC2_155      GNGGSGGLLM--GIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG
Mflv_5091|M.gilvum_PYR-GCK          GLG-ETGTTG--GAGGVGGQG----------TAGGTGGVGGIGG------
TH_3810|M.thermoresistible__bu      GSGGRTGLFSKLSRGGDGGDG----------GLGGNGGHGGGTG------
MAB_4284c|M.abscessus_ATCC_199      NTTNINDSFNTDRSTNIGSGN----------TTNTEIGSHNQANIG----
MAV_4827|M.avium_104                LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVG--
MLBr_01556|M.leprae_Br4923          RPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRP--
                                                   .  . .                             

Mb3543|M.bovis_AF2122/97            --------RGALLLGAGGQGGLGGAGGQGGMGGAGGAGADNPT------G
Rv3508|M.tuberculosis_H37Rv         --------RGALLLGAGGQGGLGGAGGQGGTGGAGGDGVLG--------G
MUL_0740|M.ulcerans_Agy99           ------------LFGPGGAGGPGGAGGNGGAGGSGGALADD---------
MMAR_4270|M.marinum_M               -------------ATSGTGGGVGENGGPGDSSTVTGEEGGD---------
Mvan_2459|M.vanbaalenii_PYR-1       --------IF------ASTGNGG-DGGHGADGGPG---------------
MSMEG_0868|M.smegmatis_MC2_155      GIGGTGGGLFGLLGHSGSTGAAG-AAGNGGDGGNGGFGYVLIAGPNVTVG
Mflv_5091|M.gilvum_PYR-GCK          ---------------AGSTGAVGGVGGKGIQGGQGLQG------------
TH_3810|M.thermoresistible__bu      ------------IISLLSLAGNGGNGGNGYRTTDNN--------------
MAB_4284c|M.abscessus_ATCC_199      --------------TSTSAGGSAAVGGNAGLAGNAGLAGN----------
MAV_4827|M.avium_104                ---------------EEDAESPTVVIEKLFLPEDSEPRRRP--------V
MLBr_01556|M.leprae_Br4923          ---------------GQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQ
                                                                                      

Mb3543|M.bovis_AF2122/97            IGGTGGDGGTGGSAGEGGAGGAAGQLFSASGAAGNAGVG---------GA
Rv3508|M.tuberculosis_H37Rv         VGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVG---------GT
MUL_0740|M.ulcerans_Agy99           -GGDGGAGGAGGIGGNGGAG--------TTGLAGHIGID---------MN
MMAR_4270|M.marinum_M               -GGSGGQGSPGASTASGGTGG-------DGGLAGDGGPG---------AP
Mvan_2459|M.vanbaalenii_PYR-1       --TRGGHGGAGGDAGR---------------------------------L
MSMEG_0868|M.smegmatis_MC2_155      SETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAI
Mflv_5091|M.gilvum_PYR-GCK          --GKGGDGGAGGKGGDADSMG---------------------------SA
TH_3810|M.thermoresistible__bu      -ALDGGHGGNGGNVGFFSLFN----------------------------L
MAB_4284c|M.abscessus_ATCC_199      -AGLAGNAGLAGNAGLAGNAG----------------------------L
MAV_4827|M.avium_104                LLVGSGLAVVGISAVLALEIALAIG----------------------IRT
MLBr_01556|M.leprae_Br4923          APVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMV
                                        .*                                            

Mb3543|M.bovis_AF2122/97            GGQGGDGGAGGAGADADQ-PGATGGTGFAGG-----AGGAGGAGGSSGAG
Rv3508|M.tuberculosis_H37Rv         GGQGGAGGAGAAGADAPASTGLTGGTGFAGG-----AGGVGGQGGNAIAG
MUL_0740|M.ulcerans_Agy99           GGAGGVGGAGGN-----------GGAGGTGG-----DAGHAQAGGYS--D
MMAR_4270|M.marinum_M               GGTGGGGGNGGA-----------GANNFSGG-----SATSGGAGGNGNNG
Mvan_2459|M.vanbaalenii_PYR-1       HGNGGAGGNG--------------GNGGVG------VDSVNPSAGGSAAA
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGNGSTTA--------AGGNGGTGGTGRVIAEGTGSTAEGTATG
Mflv_5091|M.gilvum_PYR-GCK          GATGGKGGNG--------------GNGGRGG-----LFGKGGNAGNGADG
TH_3810|M.thermoresistible__bu      GGAGGWGGSG--------------------------VDGVDVVGGNP---
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAG-------------------------LAGNAGLAGNAGLA
MAV_4827|M.avium_104                TGTVALQPTPN-------------------------QHLIVPTEQAPAPP
MLBr_01556|M.leprae_Br4923          TATQSVGDETLELLG-------------------SEMNYNVQVVSPEDED
                                     .  .                                             

Mb3543|M.bovis_AF2122/97            GTNGSGGAGGTGGQGGMGGAGGAGADNPT--GIGGTGGDGGTGGAA----
Rv3508|M.tuberculosis_H37Rv         GINGSGGAGGTGGQGGAGGMGGSGADNAS--GIGADGGAGGTGGNA----
MUL_0740|M.ulcerans_Agy99           GLQGAGGDGGHGGSGGVAGDGGRGADAAA--GSGLAGGDGGRGGDP----
MMAR_4270|M.marinum_M               GTGGDGAAGGDGGNGGNGGSGGTTTSKVSNAGSGANGGDGGDGGDG----
Mvan_2459|M.vanbaalenii_PYR-1       G-----SPNYLGTTG-----FPYTN-VVVD-NA-ITGNAGGRGKD-----
MSMEG_0868|M.smegmatis_MC2_155      GDGGHSTGTGIGGNGGIGSVYAYGNNGAVS-GT-ATGGRGGDGIDGGTGG
Mflv_5091|M.gilvum_PYR-GCK          GTGGAGGAGGTGGTGGAGGTGGTGGTGGIG-GAGSTGGTGGTGGTG----
TH_3810|M.thermoresistible__bu      ------DGGTPGAHGESHTPGVY------------TDRQGEDGEDG----
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG----
MAV_4827|M.avium_104                PVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAP----
MLBr_01556|M.leprae_Br4923          RELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIR----
                                               .                                      

Mb3543|M.bovis_AF2122/97            -------------------------GAGGAGGAAGTGGT-------GGMI
Rv3508|M.tuberculosis_H37Rv         -------------------------GAGGAGGAAGTGGT-------GGVV
MUL_0740|M.ulcerans_Agy99           -------------------------GAGGEGGAAGGG----------SVA
MMAR_4270|M.marinum_M               -------------------------GAGAVGGNGGNGGK-------GGDS
Mvan_2459|M.vanbaalenii_PYR-1       -------------------------AAAGTNQSGGAGG-----------T
MSMEG_0868|M.smegmatis_MC2_155      AGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTT
Mflv_5091|M.gilvum_PYR-GCK          -------------------------GTGGTGGTGGTGG-----------T
TH_3810|M.thermoresistible__bu      -------------------------TGTGIGGRGGNGG-----------S
MAB_4284c|M.abscessus_ATCC_199      --------------------------LAGNAGLAGNAG----------LA
MAV_4827|M.avium_104                -------------------------PIPAAPPVVPVPVVVPP----VPVP
MLBr_01556|M.leprae_Br4923          ------------------------KANVREAEAGGITQHIGAYQVGVDLD
                                                                                      

Mb3543|M.bovis_AF2122/97            GTTGNAGVG-GAGGQGGDGGAGGAGADA----------------------
Rv3508|M.tuberculosis_H37Rv         GAAGKAGIG-GTGGQGGAGGAGSAGTDA----------------------
MUL_0740|M.ulcerans_Agy99           GTAGLDGIGPNSGGNGGNGGHGGSG-------------------------
MMAR_4270|M.marinum_M               GSGGFFTPSPGTGGAGGDGGHGGSG-------------------------
Mvan_2459|M.vanbaalenii_PYR-1       GQGVTGFLALPHRYNIS--GDGGDGG------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGG
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGKGGTGGTGGAGGTGGDGG------------------------
TH_3810|M.thermoresistible__bu      SSGTHPMAEDGEHVKALDGRPGLDGG------------------------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAAVAGNAAVAGNAAVAGN------------------------
MAV_4827|M.avium_104                VPVRIPVPDPVSPPQLLAPPRLSVPQP-----------------------
MLBr_01556|M.leprae_Br4923          GSERLITFIDTPGHEAFTAMRARGAKAT--------------------DI
                                                                                      

Mb3543|M.bovis_AF2122/97            --DQPGATGGTGF------------------------AGGAGGAGGAG--
Rv3508|M.tuberculosis_H37Rv         --TATGATGGTGF------------------------SGGAGGAGGAGGN
MUL_0740|M.ulcerans_Agy99           ---AVGVEGGAGS------------------------AGGAGGRGGDG--
MMAR_4270|M.marinum_M               ---SNGQAGGSGG------------------------QGGAGGNGGLLA-
Mvan_2459|M.vanbaalenii_PYR-1       ----NGAGGG---------------------------LGGDGGDAG--LA
MSMEG_0868|M.smegmatis_MC2_155      AASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWV
Mflv_5091|M.gilvum_PYR-GCK          ----TGGTGG---------------------------TGGTGGTGG----
TH_3810|M.thermoresistible__bu      -------------------------------------NGSHGGNGG----
MAB_4284c|M.abscessus_ATCC_199      -----AAVGGVLN------------------------TGVSGAIGGSS--
MAV_4827|M.avium_104                ---VQPPVRVPQ-------------------------PPSPPQVGGTVP-
MLBr_01556|M.leprae_Br4923          AILVVAADDGVMP---------------------QTVEAINHAQAADVPI
                                                                                ..    

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         TGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGA
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       QEATP---------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      QAYDPNGPAGTTIDKGKAAGGNGGDG------------------------
Mflv_5091|M.gilvum_PYR-GCK          TGGTG---------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          VVAVN---------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            ----GSSGAGGTNGSGG-----------------AGGTGGQGGAGGAGGA
Rv3508|M.tuberculosis_H37Rv         GGQGGSSGAGGTNGSGG-----------------AGGTGGQGGAGGAGGA
MUL_0740|M.ulcerans_Agy99           ----GAYGNGGVSGNGG-----------------AGGAGSPGAHGGTAGE
MMAR_4270|M.marinum_M               ----GDGGAGGAGGLGG-----------------QGGAAAAGANGGVAGN
Mvan_2459|M.vanbaalenii_PYR-1       ----TAAAFGGRGGNGG-----------------TGGTGARGGDG-----
MSMEG_0868|M.smegmatis_MC2_155      GFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVN
Mflv_5091|M.gilvum_PYR-GCK          ---GAGDGTGGTGGTGG-----------------TGGQGGQGGQGG----
TH_3810|M.thermoresistible__bu      --------HGGRGGFLG-----------------IGGSGGWGGHG-----
MAB_4284c|M.abscessus_ATCC_199      --HVGGAINESLGGSGS-----------------VGGSTAVGGGAHTG--
MAV_4827|M.avium_104                ---QSPPQHQTPPGEGT-----------------PPKPDGPGNYGG----
MLBr_01556|M.leprae_Br4923          KIDKEGADPAKIRGQLTEYG---------LVAEDFGGDTMFIDISAKVGT
                                                 *                              .     

Mb3543|M.bovis_AF2122/97            GADNPTGIGGTGGDGGTGGAAGAGG-AGGAAGTGGTGGMIGTTGNAGVGG
Rv3508|M.tuberculosis_H37Rv         GADNPTGIGGAGGTGGTGGAAGAGG-AGGAIGTGGTGGAVGSVGNAGIGG
MUL_0740|M.ulcerans_Agy99           DGFN-------AGDGGHGGAGGAGG-GGGAKG--------------GVGG
MMAR_4270|M.marinum_M               GGNG--------GHGPFGEKIPAGG-SGGDGGTG------------GIGG
Mvan_2459|M.vanbaalenii_PYR-1       ------------GAGGSVDIGQTVG-FGGHGGNG------------GAGG
MSMEG_0868|M.smegmatis_MC2_155      AGAN-----GNGGAGGAGGVSEGEGGTGGHGGDG------------GRGG
Mflv_5091|M.gilvum_PYR-GCK          ----------TGGTGGQGGLGGGGG-TGGQGGTG------------GTGG
TH_3810|M.thermoresistible__bu      ------------GNGGDTDADGGNG---------------------GDGG
MAB_4284c|M.abscessus_ATCC_199      -----------VGGGVSTGVGVGSHVGGGIS--------------ESLGG
MAV_4827|M.avium_104                ------------GHVPTPGAGGSGGSGGGHVPTP------------GAGG
MLBr_01556|M.leprae_Br4923          NIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLD--------RGRGP
                                                .                                 . * 

Mb3543|M.bovis_AF2122/97            AGGQGGDGGAG-----------------------GAGGAGGSSGAGG---
Rv3508|M.tuberculosis_H37Rv         TGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGG---
MUL_0740|M.ulcerans_Agy99           AGGSGGVGGQG-----------------------GTGGDG-ATGLSG---
MMAR_4270|M.marinum_M               DGGLGGDGGAG-----------------------GQGGAGGRAGLLAG--
Mvan_2459|M.vanbaalenii_PYR-1       TGAAGATGAAG-----------------------GNGGAGGRSG------
MSMEG_0868|M.smegmatis_MC2_155      DGALGGNGGTGGVGL-------------------GNGGKGGNGGNGGNGG
Mflv_5091|M.gilvum_PYR-GCK          QGGTGGTGGTGGTG--------------------GTGGAGGDGGLG----
TH_3810|M.thermoresistible__bu      NGGSAGRGGTG-----------------------GLRGVFGINGGNG---
MAB_4284c|M.abscessus_ATCC_199      SGSVGGSTAVG-----------------------GGAHTGVGGGVSTG--
MAV_4827|M.avium_104                SGGSGGGHVPTP----------------------GTGGPGGTGGSGGG--
MLBr_01556|M.leprae_Br4923          VATVLVQRGTLRIG--------------------DSVVAGDAYGRVRR--
                                     .                                .        *      

Mb3543|M.bovis_AF2122/97            ------TNGSGGAGG------------------TGGQGGAGGAGGAGADN
Rv3508|M.tuberculosis_H37Rv         ------TNGSGGAGG------------------AGGKGGTGGAGGSGADN
MUL_0740|M.ulcerans_Agy99           ------KAGTGTDGE------------------SGGRGGHAGNGGN----
MMAR_4270|M.marinum_M               ------LGGAGGDGG------------------LGGNGGVGGDGAQG---
Mvan_2459|M.vanbaalenii_PYR-1       -----SRTGNGGAGG------------------AAGNGGSGGNG------
MSMEG_0868|M.smegmatis_MC2_155      TYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHR
Mflv_5091|M.gilvum_PYR-GCK          -----GLGGFGGSGG------------------TGGQGGLGGPGG-----
TH_3810|M.thermoresistible__bu      ------RAGLGGRGX------------------XXXGGGVGAAVR-----
MAB_4284c|M.abscessus_ATCC_199      -------VGVGSHVG------------------GGISESLGGSGS-----
MAV_4827|M.avium_104                ---HVPTPGAGTPGGS-----------------GGGHLPFPGAGSTP---
MLBr_01556|M.leprae_Br4923          ---MVDEHGVDIEAALP-----------SSPVQVIGFTSVPGAGDNFLVV
                                            * .                              .        

Mb3543|M.bovis_AF2122/97            PTGIG-------------------GTGGDGGTGGAAGAGGAGGAAGTGG-
Rv3508|M.tuberculosis_H37Rv         PTGAG-------------------FAGGAGGTGGAAGAGGAGGATGTGG-
MUL_0740|M.ulcerans_Agy99           --------------------------GGNGGRGGSAHASLVG-KAGNGG-
MMAR_4270|M.marinum_M               ------------------------GLGGNGGVRNSDNLSYDG-IIGNGG-
Mvan_2459|M.vanbaalenii_PYR-1       ------------------------ATGGDGGSGGVGGAD-----------
MSMEG_0868|M.smegmatis_MC2_155      GGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVA
Mflv_5091|M.gilvum_PYR-GCK          ------------------------STGGAGGAGGQAGTAGKGGLFGGSGS
TH_3810|M.thermoresistible__bu      --------------------------SGNGVFSGGGGTPSAG--------
MAB_4284c|M.abscessus_ATCC_199      -------------------------VGGSTAVGGGAHTGVGGGVNTGVG-
MAV_4827|M.avium_104                -------------------------GGSGGGHLPTPGAGTPGGGLGGFG-
MLBr_01556|M.leprae_Br4923          DEDRIAR----------------QIADRRSARKRNALAARSRKRISLEDL
                                                              .                       

Mb3543|M.bovis_AF2122/97            -----TGGMIGTTGNAGVGGAGGQGGDGG---------------------
Rv3508|M.tuberculosis_H37Rv         -----TGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQG
MUL_0740|M.ulcerans_Agy99           -----FGGTGGNS-FGGVSGNGGNGGDGG---------------------
MMAR_4270|M.marinum_M               -----TGGNGGVGGHGGDGGAGGEGGSGS---------------------
Mvan_2459|M.vanbaalenii_PYR-1       -----VSDPGSGPVTAGTGG---NGGSGG---------------------
MSMEG_0868|M.smegmatis_MC2_155      YNVVQANPQASGTATDGHGGSGINGGHGGNGG------------------
Mflv_5091|M.gilvum_PYR-GCK          AG--KAGATGAAGASGGKGAQGATGAQGATGA------------------
TH_3810|M.thermoresistible__bu      -----FGVPTTIQFPAGSCTSRAVSREGI---------------------
MAB_4284c|M.abscessus_ATCC_199      -----VGSHVGGGISESLGGSGSVGGSTAVG-------------------
MAV_4827|M.avium_104                ------GGHAPAPGGGLGGGGGHAPAPGG---------------------
MLBr_01556|M.leprae_Br4923          DSALKETSQLNLILKGDNAGTVEALEEALMG-------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GAGGSAGAGGINGAGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAA
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            ---------------------------AGGAGADADQ-------------
Rv3508|M.tuberculosis_H37Rv         GNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQG
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            -----------------------------------------PGATGG---
Rv3508|M.tuberculosis_H37Rv         GQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGG
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            ----------------------------------------TGFAGGAG--
Rv3508|M.tuberculosis_H37Rv         DAGSGGGGGFGGAAGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQG--
MUL_0740|M.ulcerans_Agy99           ----------------------------------------HALHGQPG--
MMAR_4270|M.marinum_M               ----------------------------------------LLGAAGSA--
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------------QGTIEANGPS
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------QGATGATG--
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ------------------------------------------IQVDDEVA
                                                                                      

Mb3543|M.bovis_AF2122/97            ------GAGGAGGSSGAGGTNGSGGAGG----------------------
Rv3508|M.tuberculosis_H37Rv         ------GQGGAGGSAGAGGINGAGGAGGNGGDGGDGATGAAGLGDNGGVG
MUL_0740|M.ulcerans_Agy99           ------GHGGQGGHGGVAHIDGSDYPGWP---------------------
MMAR_4270|M.marinum_M               ------GSNAAGGSGGTGGLRGQG--------------------------
Mvan_2459|M.vanbaalenii_PYR-1       -------AGGAGGDGGAGGLGGKGG-------------------------
MSMEG_0868|M.smegmatis_MC2_155      AVASGIGAGGNGGDGIDGGLGGNGGDGVV---------------------
Mflv_5091|M.gilvum_PYR-GCK          ------AAGKAGATGAAGAAGAAGSAG-----------------------
TH_3810|M.thermoresistible__bu      ------MPSSRAASARAGAACASS--------------------------
MAB_4284c|M.abscessus_ATCC_199      --------GGAHTSAINDALGGSGSVGG----------------------
MAV_4827|M.avium_104                ------GLGGFGGGHSGGGLGGLGGGHK----------------------
MLBr_01556|M.leprae_Br4923          LRVIDRGVGGITETNVNLASASDAIIIG----------------------
                                            .            .                            

Mb3543|M.bovis_AF2122/97            ------------------------------TGGQGGAGGAG---------
Rv3508|M.tuberculosis_H37Rv         GDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNG
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            ---------------------ISFSNGS--NGGTGGTGGVG---------
Rv3508|M.tuberculosis_H37Rv         GQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGG
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      -----------------NTTANAANPGSATGTATGGDGGKA---------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         SGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLS
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGPDGGD
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------GTGGDGGNAG---------TGAGDPGKGGT
Rv3508|M.tuberculosis_H37Rv         GGQGGIGGDGGNAGFGAGVPGDGGDGGNAG---------FGAGVPGDGGI
MUL_0740|M.ulcerans_Agy99           -----------------------GLPGDVG---------YQDG---TGGG
MMAR_4270|M.marinum_M               -----------------------GDPGSTGR--------AGTGSAGADGM
Mvan_2459|M.vanbaalenii_PYR-1       ----------------------------------------------AGSS
MSMEG_0868|M.smegmatis_MC2_155      -------------------TGTASQGGNGGPSWVQSGYGSTLGGNATGTA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------------TTGA
TH_3810|M.thermoresistible__bu      ----------------------------------------------TSRS
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------------STAV
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ---------------------------------------------FNVRA
                                                                                      

Mb3543|M.bovis_AF2122/97            GGTGGSGGAGGS------------GGAN----------------------
Rv3508|M.tuberculosis_H37Rv         GGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASG
MUL_0740|M.ulcerans_Agy99           GGTGGAGGHAP---------------------------------------
MMAR_4270|M.marinum_M               NGTDGDPGDPGGMA------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       EGSAGADAANG---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TAGKGGEASNGGVAGNGGNALVMAAGTTGVAT------------------
Mflv_5091|M.gilvum_PYR-GCK          QGSAGTNGANG---------------------------------------
TH_3810|M.thermoresistible__bu      RRSFCCSRA-----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGGAHTSAINESMN------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          EGKATELASREGVEIR----------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            -------------------FNGGTGGTGGTG-------------------
Rv3508|M.tuberculosis_H37Rv         DGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAG
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       ----------------------ATG-------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------GNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHG
Mflv_5091|M.gilvum_PYR-GCK          ----------------------ANGSQG----------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            -------------------------------------------------G
Rv3508|M.tuberculosis_H37Rv         IGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGG
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      G-------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            TGGKGGMGG-----------------------------------------
Rv3508|M.tuberculosis_H37Rv         TGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVP
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLA
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            -------------------------IAGDGGPGGDGGNAGVG--------
Rv3508|M.tuberculosis_H37Rv         SAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGT
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------AGNGGNGGKGADGWVQAYDPAGPV
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         AGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGI
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GSKIANSSA-----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         NGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGF
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLN
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3543|M.bovis_AF2122/97            ---------------------------------GKGGTNGNGGSGGTGGT
Rv3508|M.tuberculosis_H37Rv         STGLASAASGDGGNGGAGGAGGNGGAGGLGGGGGTGGTNGNGGLGGGGGN
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       -------------------------------VGGSGGAGGRGGTGGASG-
MSMEG_0868|M.smegmatis_MC2_155      -------------------------------VAGNGGDGGVNGTGGASGG
Mflv_5091|M.gilvum_PYR-GCK          -------------------------------AAGKAGATGTTGATGAAGE
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------SSINASHSSSMNESFGSSMGS
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ------------------------YYLVIYQAIDDIEKALRGMLKPIYEE
                                                                                      

Mb3543|M.bovis_AF2122/97            GGPGGSGGAPTGSGTGGKGGAGGDGGDGADGGAATG--VGDGGDGGNGGN
Rv3508|M.tuberculosis_H37Rv         GGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATG--VGNGGNGGDGGN
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4270|M.marinum_M               --------------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       DGASGG------SGG---AGKPGTGPTGSKGG-----------AGGSGGS
MSMEG_0868|M.smegmatis_MC2_155      DGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGN
Mflv_5091|M.gilvum_PYR-GCK          DGDAGSGGSGINGGAGGAGGAGGEGGEGGDGGKG-----GAGAEGGAGGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      HGAAGTGFEAQGHAQGHASETAHTTLPGAEHH------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          NQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLT
                                                                                      

Mb3543|M.bovis_AF2122/97            GGNGGTGVGSPGGLGGAGGTGGLGGAGAGGGADGDDGDDGQPGNNGS
Rv3508|M.tuberculosis_H37Rv         GGDGGN--GAPGGFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS
MUL_0740|M.ulcerans_Agy99           -----------------------------------------------
MMAR_4270|M.marinum_M               -----------------------------------------------
Mvan_2459|M.vanbaalenii_PYR-1       GGSGGQAD---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-------
Mflv_5091|M.gilvum_PYR-GCK          GGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD-------
TH_3810|M.thermoresistible__bu      -----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------------
MAV_4827|M.avium_104                -----------------------------------------------
MLBr_01556|M.leprae_Br4923          VTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA-