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MARRLSKTVDASDGNILRCAGAGPRYWIAAGTGGAAVMGVGLLAGLCSETPATVERPVRLASFDSLIVAN SPVPEDIWLFGAAGSPKRDRSGPATAAAPGVAAVRPMIGPGGWLIGDGADAVEDCEGSACDGRNGGVLWG NGGNGARGGKGGNAGMFGGNGGRGGDGYLPGQDGGDGGDAGIFASTGNGGDGGHGADGGPGTRGGHGGAG GDAGRLHGNGGAGGNGGNGGVGVDSVNPSAGGSAAAGSPNYLGTTGFPYTNVVVDNAITGNAGGRGKDAA AGTNQSGGAGGTGQGVTGFLALPHRYNISGDGGDGGNGAGGGLGGDGGDAGLAQEATPTAAAFGGRGGNG GTGGTGARGGDGGAGGSVDIGQTVGFGGHGGNGGAGGTGAAGATGAAGGNGGAGGRSGSRTGNGGAGGAA GNGGSGGNGATGGDGGSGGVGGADVSDPGSGPVTAGTGGNGGSGGAGGAGGDGGAGGLGGKGGAGSSEGS AGADAANGATGVGGSGGAGGRGGTGGASGDGASGGSGGAGKPGTGPTGSKGGAGGSGGSGGSGGQAD
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2459 | - | - | 100% (557) | PE_PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-95 | 41.00% (539) | triple helix repeat-containing collagen |
M. vanbaalenii PYR-1 | Mvan_5240 | - | 9e-85 | 40.60% (532) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | 1e-102 | 45.24% (515) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-101 | 41.32% (547) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 1e-100 | 44.74% (523) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 7e-09 | 35.77% (137) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 9e-42 | 33.72% (433) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_4270 | - | 1e-98 | 44.47% (515) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 1e-23 | 44.03% (159) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-73 | 35.71% (644) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 4e-44 | 35.84% (385) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0740 | - | 7e-94 | 42.80% (500) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3543|M.bovis_AF2122/97 ----------------------------------MSFVLIAPEFVTAAAG Rv3508|M.tuberculosis_H37Rv ----------------------------------MSFVLIAPEFVTAAAG MUL_0740|M.ulcerans_Agy99 ----------------------------------MSFVSVSPELVIDGAA MMAR_4270|M.marinum_M ----------------------------------MSFVFAVPETMAAVTS Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES Mflv_5091|M.gilvum_PYR-GCK ----MVTFGGGATPTPTSLGAAAVDLSGTSCG---LICNGQDGTGQNGGI TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------MSIIDFILNLFRDPVEAASYVADP MAV_4827|M.avium_104 ---------------------MNIVLGVSMAPSSIQMVVLEGEYADGATV MLBr_01556|M.leprae_Br4923 ------------------------------MAGKARVHELAKELGVTSKE Mb3543|M.bovis_AF2122/97 DLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFG-----LE Rv3508|M.tuberculosis_H37Rv DLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFG-----LE MUL_0740|M.ulcerans_Agy99 ALTQIGSSIDEANAAAG-ATRAVLPPGVDEVSVALAALFVAHG-----RE MMAR_4270|M.marinum_M ELATIGSNLEMANAAAALPTTGLLAAGADEVSAAIAALFDEHA-----LG Mvan_2459|M.vanbaalenii_PYR-1 ----MARRLSKTVDASDG---NILRCAG----AGPRYWIAAGT------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT Mflv_5091|M.gilvum_PYR-GCK LFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGGNAG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGN------P MAV_4827|M.avium_104 EEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQ MLBr_01556|M.leprae_Br4923 VLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQ Mb3543|M.bovis_AF2122/97 YQAISAQVAAYHQRFVQALSTGAGAYASAEAA---------AAEQIVLGV Rv3508|M.tuberculosis_H37Rv YQAISAQVAAYHQRFVQALSTGAGAYASAEAA---------AAEQIVLGV MUL_0740|M.ulcerans_Agy99 YESLSAQVALFHRRFVQMLAAASGGYAEAEAANISAVAGLETVEQCVLDV MMAR_4270|M.marinum_M YQTISAQASAFHARFMSALNTGAGAYAAAEAANSSP---LQALQDLTLNA Mvan_2459|M.vanbaalenii_PYR-1 ----GGAAVMGVGLLAGLCSETPATVERPVR----------LASFDSLIV MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGL---LSVVTLGTTLI Mflv_5091|M.gilvum_PYR-GCK AFALFGNGGNGGNGGVGVVGATGAVGAPGVAGATG------ATGVTSGVV TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 IHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIAS MAV_4827|M.avium_104 LEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGG---AMGYERTAVLL MLBr_01556|M.leprae_Br4923 AKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHS------AAVVPIVA Mb3543|M.bovis_AF2122/97 INAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGNG------------ Rv3508|M.tuberculosis_H37Rv INAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGNG------------ MUL_0740|M.ulcerans_Agy99 INAPTQALFGWSLIGNGTDGAPGSGQAGGNGGLLWGNG------------ MMAR_4270|M.marinum_M INAPAQSLFGRPLIGDGAN-ATTPGGNGGAGGILWGNG------------ Mvan_2459|M.vanbaalenii_PYR-1 ANSPVP----EDIWLFGAAGSPKRDRSGPATAAAPG-------------- MSMEG_0868|M.smegmatis_MC2_155 PNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAV Mflv_5091|M.gilvum_PYR-GCK GGNGEDAVGYGATGAAGAAGAAGAAGAAGAVGSAGAAG------------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG------------ MAV_4827|M.avium_104 VEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG-------------- MLBr_01556|M.leprae_Br4923 GEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPG---------- Mb3543|M.bovis_AF2122/97 ------------------------GAGAAGAPGQAGGPGGPAGLWGNGGP Rv3508|M.tuberculosis_H37Rv ------------------------GAGAAGAPGQAGGPGGPAGLWGNGGP MUL_0740|M.ulcerans_Agy99 ------------------------GNGGSGGVGQAGGAGGSAGLLGHGGA MMAR_4270|M.marinum_M ------------------------GAGATGAAGQTGGNGGAAGFIGNGGA Mvan_2459|M.vanbaalenii_PYR-1 ------------------------VAAVRPMIG------PGGWLIGDGAD MSMEG_0868|M.smegmatis_MC2_155 LDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGIN Mflv_5091|M.gilvum_PYR-GCK ------------------------EAGETGTWGNAGLPGKAGDAGGAGAV TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------DGAVAVGGSNSGPIASGQGSTAVNGDV MAV_4827|M.avium_104 -----------------------QLSAMVAGLEKLESLPGGLLLVGSGVD MLBr_01556|M.leprae_Br4923 ----------------------HPGMPTGPHPGPAPKPGGRPPRVGNNPF Mb3543|M.bovis_AF2122/97 GGAGGSGGGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGG Rv3508|M.tuberculosis_H37Rv GGAGGSGGGTGGAGGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGG MUL_0740|M.ulcerans_Agy99 GGAGG-----------------VSGVSAVG----ATGGAGGNGGWLYGNG MMAR_4270|M.marinum_M GGAGGAG---------------------------ATGGVGGSGGMLFGNG Mvan_2459|M.vanbaalenii_PYR-1 AVED-----------------------CEGSAC---DGRNGG--VLWGNG MSMEG_0868|M.smegmatis_MC2_155 GTADNPNGGTGGL------LFGDGGHGYDGSAAGL-AGGNGGNAGLFGNG Mflv_5091|M.gilvum_PYR-GCK GAAG-----------------AAGTVGTAGATGGTGTGANGGAGGVGGVG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 RDSNIIN----------------ADHGSNVGVDQSQTRVGGDYTNVSGHG MAV_4827|M.avium_104 VAPLK---------------------QVLQTTTFLDVSVAEEPETALARG MLBr_01556|M.leprae_Br4923 SSAQSVAR--------------PIPRPPAPRPSASPSSMSPRPGGAVGGG Mb3543|M.bovis_AF2122/97 GAGGVGGAGGGTGGAGGRAELLFGAGGAGGAGGAGTDGGPGATGGTGGHG Rv3508|M.tuberculosis_H37Rv GAGGVGGAGGGTGGAGGRAELLFGAGGAG---GAGTDGGPGATGGTGGHG MUL_0740|M.ulcerans_Agy99 GAGGLGGQGVLIG----------------------------------GNG MMAR_4270|M.marinum_M GAGGNGGTAMVVGG-------------------------------TGGNG Mvan_2459|M.vanbaalenii_PYR-1 GNGAR--------------------------------------------G MSMEG_0868|M.smegmatis_MC2_155 GNGGVGWA--------------------------------------GLDG Mflv_5091|M.gilvum_PYR-GCK GTGAAGAA--------------------------------------GGAG TH_3810|M.thermoresistible__bu ---------------------------------------------VDGDG MAB_4284c|M.abscessus_ATCC_199 SADIDKSVTVVDD---------------------------------HSQR MAV_4827|M.avium_104 AALAAAN-----------------------------------------AP MLBr_01556|M.leprae_Br4923 GPRPPRTGVPR-----------------------------------PGGG Mb3543|M.bovis_AF2122/97 GVGGDGGWLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGG Rv3508|M.tuberculosis_H37Rv GVGGDGGWLAPGGAGGAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGG MUL_0740|M.ulcerans_Agy99 GAGGAARFFGAGGTGGAGGLG-----------LGDTGGIGGIGGNAGA-- MMAR_4270|M.marinum_M GAGGSAGLFGAGGAGGQGGQG----------AQGPDAVNPGPVSPTGQ-- Mvan_2459|M.vanbaalenii_PYR-1 GKGGNAGMFG--GNGGRGGDG---------YLPGQDGGDGGDAG------ MSMEG_0868|M.smegmatis_MC2_155 GNGGSGGLLM--GIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG Mflv_5091|M.gilvum_PYR-GCK GLG-ETGTTG--GAGGVGGQG----------TAGGTGGVGGIGG------ TH_3810|M.thermoresistible__bu GSGGRTGLFSKLSRGGDGGDG----------GLGGNGGHGGGTG------ MAB_4284c|M.abscessus_ATCC_199 NTTNINDSFNTDRSTNIGSGN----------TTNTEIGSHNQANIG---- MAV_4827|M.avium_104 LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVG-- MLBr_01556|M.leprae_Br4923 RPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRP-- . . . Mb3543|M.bovis_AF2122/97 --------RGALLLGAGGQGGLGGAGGQGGMGGAGGAGADNPT------G Rv3508|M.tuberculosis_H37Rv --------RGALLLGAGGQGGLGGAGGQGGTGGAGGDGVLG--------G MUL_0740|M.ulcerans_Agy99 ------------LFGPGGAGGPGGAGGNGGAGGSGGALADD--------- MMAR_4270|M.marinum_M -------------ATSGTGGGVGENGGPGDSSTVTGEEGGD--------- Mvan_2459|M.vanbaalenii_PYR-1 --------IF------ASTGNGG-DGGHGADGGPG--------------- MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAG-AAGNGGDGGNGGFGYVLIAGPNVTVG Mflv_5091|M.gilvum_PYR-GCK ---------------AGSTGAVGGVGGKGIQGGQGLQG------------ TH_3810|M.thermoresistible__bu ------------IISLLSLAGNGGNGGNGYRTTDNN-------------- MAB_4284c|M.abscessus_ATCC_199 --------------TSTSAGGSAAVGGNAGLAGNAGLAGN---------- MAV_4827|M.avium_104 ---------------EEDAESPTVVIEKLFLPEDSEPRRRP--------V MLBr_01556|M.leprae_Br4923 ---------------GQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQ Mb3543|M.bovis_AF2122/97 IGGTGGDGGTGGSAGEGGAGGAAGQLFSASGAAGNAGVG---------GA Rv3508|M.tuberculosis_H37Rv VGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVG---------GT MUL_0740|M.ulcerans_Agy99 -GGDGGAGGAGGIGGNGGAG--------TTGLAGHIGID---------MN MMAR_4270|M.marinum_M -GGSGGQGSPGASTASGGTGG-------DGGLAGDGGPG---------AP Mvan_2459|M.vanbaalenii_PYR-1 --TRGGHGGAGGDAGR---------------------------------L MSMEG_0868|M.smegmatis_MC2_155 SETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAI Mflv_5091|M.gilvum_PYR-GCK --GKGGDGGAGGKGGDADSMG---------------------------SA TH_3810|M.thermoresistible__bu -ALDGGHGGNGGNVGFFSLFN----------------------------L MAB_4284c|M.abscessus_ATCC_199 -AGLAGNAGLAGNAGLAGNAG----------------------------L MAV_4827|M.avium_104 LLVGSGLAVVGISAVLALEIALAIG----------------------IRT MLBr_01556|M.leprae_Br4923 APVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMV .* Mb3543|M.bovis_AF2122/97 GGQGGDGGAGGAGADADQ-PGATGGTGFAGG-----AGGAGGAGGSSGAG Rv3508|M.tuberculosis_H37Rv GGQGGAGGAGAAGADAPASTGLTGGTGFAGG-----AGGVGGQGGNAIAG MUL_0740|M.ulcerans_Agy99 GGAGGVGGAGGN-----------GGAGGTGG-----DAGHAQAGGYS--D MMAR_4270|M.marinum_M GGTGGGGGNGGA-----------GANNFSGG-----SATSGGAGGNGNNG Mvan_2459|M.vanbaalenii_PYR-1 HGNGGAGGNG--------------GNGGVG------VDSVNPSAGGSAAA MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGSTTA--------AGGNGGTGGTGRVIAEGTGSTAEGTATG Mflv_5091|M.gilvum_PYR-GCK GATGGKGGNG--------------GNGGRGG-----LFGKGGNAGNGADG TH_3810|M.thermoresistible__bu GGAGGWGGSG--------------------------VDGVDVVGGNP--- MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAG-------------------------LAGNAGLAGNAGLA MAV_4827|M.avium_104 TGTVALQPTPN-------------------------QHLIVPTEQAPAPP MLBr_01556|M.leprae_Br4923 TATQSVGDETLELLG-------------------SEMNYNVQVVSPEDED . . Mb3543|M.bovis_AF2122/97 GTNGSGGAGGTGGQGGMGGAGGAGADNPT--GIGGTGGDGGTGGAA---- Rv3508|M.tuberculosis_H37Rv GINGSGGAGGTGGQGGAGGMGGSGADNAS--GIGADGGAGGTGGNA---- MUL_0740|M.ulcerans_Agy99 GLQGAGGDGGHGGSGGVAGDGGRGADAAA--GSGLAGGDGGRGGDP---- MMAR_4270|M.marinum_M GTGGDGAAGGDGGNGGNGGSGGTTTSKVSNAGSGANGGDGGDGGDG---- Mvan_2459|M.vanbaalenii_PYR-1 G-----SPNYLGTTG-----FPYTN-VVVD-NA-ITGNAGGRGKD----- MSMEG_0868|M.smegmatis_MC2_155 GDGGHSTGTGIGGNGGIGSVYAYGNNGAVS-GT-ATGGRGGDGIDGGTGG Mflv_5091|M.gilvum_PYR-GCK GTGGAGGAGGTGGTGGAGGTGGTGGTGGIG-GAGSTGGTGGTGGTG---- TH_3810|M.thermoresistible__bu ------DGGTPGAHGESHTPGVY------------TDRQGEDGEDG---- MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG---- MAV_4827|M.avium_104 PVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAP---- MLBr_01556|M.leprae_Br4923 RELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIR---- . Mb3543|M.bovis_AF2122/97 -------------------------GAGGAGGAAGTGGT-------GGMI Rv3508|M.tuberculosis_H37Rv -------------------------GAGGAGGAAGTGGT-------GGVV MUL_0740|M.ulcerans_Agy99 -------------------------GAGGEGGAAGGG----------SVA MMAR_4270|M.marinum_M -------------------------GAGAVGGNGGNGGK-------GGDS Mvan_2459|M.vanbaalenii_PYR-1 -------------------------AAAGTNQSGGAGG-----------T MSMEG_0868|M.smegmatis_MC2_155 AGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTT Mflv_5091|M.gilvum_PYR-GCK -------------------------GTGGTGGTGGTGG-----------T TH_3810|M.thermoresistible__bu -------------------------TGTGIGGRGGNGG-----------S MAB_4284c|M.abscessus_ATCC_199 --------------------------LAGNAGLAGNAG----------LA MAV_4827|M.avium_104 -------------------------PIPAAPPVVPVPVVVPP----VPVP MLBr_01556|M.leprae_Br4923 ------------------------KANVREAEAGGITQHIGAYQVGVDLD Mb3543|M.bovis_AF2122/97 GTTGNAGVG-GAGGQGGDGGAGGAGADA---------------------- Rv3508|M.tuberculosis_H37Rv GAAGKAGIG-GTGGQGGAGGAGSAGTDA---------------------- MUL_0740|M.ulcerans_Agy99 GTAGLDGIGPNSGGNGGNGGHGGSG------------------------- MMAR_4270|M.marinum_M GSGGFFTPSPGTGGAGGDGGHGGSG------------------------- Mvan_2459|M.vanbaalenii_PYR-1 GQGVTGFLALPHRYNIS--GDGGDGG------------------------ MSMEG_0868|M.smegmatis_MC2_155 GGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGG Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGKGGTGGTGGAGGTGGDGG------------------------ TH_3810|M.thermoresistible__bu SSGTHPMAEDGEHVKALDGRPGLDGG------------------------ MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAAVAGNAAVAGNAAVAGN------------------------ MAV_4827|M.avium_104 VPVRIPVPDPVSPPQLLAPPRLSVPQP----------------------- MLBr_01556|M.leprae_Br4923 GSERLITFIDTPGHEAFTAMRARGAKAT--------------------DI Mb3543|M.bovis_AF2122/97 --DQPGATGGTGF------------------------AGGAGGAGGAG-- Rv3508|M.tuberculosis_H37Rv --TATGATGGTGF------------------------SGGAGGAGGAGGN MUL_0740|M.ulcerans_Agy99 ---AVGVEGGAGS------------------------AGGAGGRGGDG-- MMAR_4270|M.marinum_M ---SNGQAGGSGG------------------------QGGAGGNGGLLA- Mvan_2459|M.vanbaalenii_PYR-1 ----NGAGGG---------------------------LGGDGGDAG--LA MSMEG_0868|M.smegmatis_MC2_155 AASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWV Mflv_5091|M.gilvum_PYR-GCK ----TGGTGG---------------------------TGGTGGTGG---- TH_3810|M.thermoresistible__bu -------------------------------------NGSHGGNGG---- MAB_4284c|M.abscessus_ATCC_199 -----AAVGGVLN------------------------TGVSGAIGGSS-- MAV_4827|M.avium_104 ---VQPPVRVPQ-------------------------PPSPPQVGGTVP- MLBr_01556|M.leprae_Br4923 AILVVAADDGVMP---------------------QTVEAINHAQAADVPI .. Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv TGVGGTNGSGGQGGTGGAGGAGGAGGVGADNPTGIGGTGGTGGKGGAGGA MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 QEATP--------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 QAYDPNGPAGTTIDKGKAAGGNGGDG------------------------ Mflv_5091|M.gilvum_PYR-GCK TGGTG--------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VVAVN--------------------------------------------- Mb3543|M.bovis_AF2122/97 ----GSSGAGGTNGSGG-----------------AGGTGGQGGAGGAGGA Rv3508|M.tuberculosis_H37Rv GGQGGSSGAGGTNGSGG-----------------AGGTGGQGGAGGAGGA MUL_0740|M.ulcerans_Agy99 ----GAYGNGGVSGNGG-----------------AGGAGSPGAHGGTAGE MMAR_4270|M.marinum_M ----GDGGAGGAGGLGG-----------------QGGAAAAGANGGVAGN Mvan_2459|M.vanbaalenii_PYR-1 ----TAAAFGGRGGNGG-----------------TGGTGARGGDG----- MSMEG_0868|M.smegmatis_MC2_155 GFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVN Mflv_5091|M.gilvum_PYR-GCK ---GAGDGTGGTGGTGG-----------------TGGQGGQGGQGG---- TH_3810|M.thermoresistible__bu --------HGGRGGFLG-----------------IGGSGGWGGHG----- MAB_4284c|M.abscessus_ATCC_199 --HVGGAINESLGGSGS-----------------VGGSTAVGGGAHTG-- MAV_4827|M.avium_104 ---QSPPQHQTPPGEGT-----------------PPKPDGPGNYGG---- MLBr_01556|M.leprae_Br4923 KIDKEGADPAKIRGQLTEYG---------LVAEDFGGDTMFIDISAKVGT * . Mb3543|M.bovis_AF2122/97 GADNPTGIGGTGGDGGTGGAAGAGG-AGGAAGTGGTGGMIGTTGNAGVGG Rv3508|M.tuberculosis_H37Rv GADNPTGIGGAGGTGGTGGAAGAGG-AGGAIGTGGTGGAVGSVGNAGIGG MUL_0740|M.ulcerans_Agy99 DGFN-------AGDGGHGGAGGAGG-GGGAKG--------------GVGG MMAR_4270|M.marinum_M GGNG--------GHGPFGEKIPAGG-SGGDGGTG------------GIGG Mvan_2459|M.vanbaalenii_PYR-1 ------------GAGGSVDIGQTVG-FGGHGGNG------------GAGG MSMEG_0868|M.smegmatis_MC2_155 AGAN-----GNGGAGGAGGVSEGEGGTGGHGGDG------------GRGG Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGQGGLGGGGG-TGGQGGTG------------GTGG TH_3810|M.thermoresistible__bu ------------GNGGDTDADGGNG---------------------GDGG MAB_4284c|M.abscessus_ATCC_199 -----------VGGGVSTGVGVGSHVGGGIS--------------ESLGG MAV_4827|M.avium_104 ------------GHVPTPGAGGSGGSGGGHVPTP------------GAGG MLBr_01556|M.leprae_Br4923 NIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLD--------RGRGP . . * Mb3543|M.bovis_AF2122/97 AGGQGGDGGAG-----------------------GAGGAGGSSGAGG--- Rv3508|M.tuberculosis_H37Rv TGGTGGVGGAGGAGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGG--- MUL_0740|M.ulcerans_Agy99 AGGSGGVGGQG-----------------------GTGGDG-ATGLSG--- MMAR_4270|M.marinum_M DGGLGGDGGAG-----------------------GQGGAGGRAGLLAG-- Mvan_2459|M.vanbaalenii_PYR-1 TGAAGATGAAG-----------------------GNGGAGGRSG------ MSMEG_0868|M.smegmatis_MC2_155 DGALGGNGGTGGVGL-------------------GNGGKGGNGGNGGNGG Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGTGGTG--------------------GTGGAGGDGGLG---- TH_3810|M.thermoresistible__bu NGGSAGRGGTG-----------------------GLRGVFGINGGNG--- MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVG-----------------------GGAHTGVGGGVSTG-- MAV_4827|M.avium_104 SGGSGGGHVPTP----------------------GTGGPGGTGGSGGG-- MLBr_01556|M.leprae_Br4923 VATVLVQRGTLRIG--------------------DSVVAGDAYGRVRR-- . . * Mb3543|M.bovis_AF2122/97 ------TNGSGGAGG------------------TGGQGGAGGAGGAGADN Rv3508|M.tuberculosis_H37Rv ------TNGSGGAGG------------------AGGKGGTGGAGGSGADN MUL_0740|M.ulcerans_Agy99 ------KAGTGTDGE------------------SGGRGGHAGNGGN---- MMAR_4270|M.marinum_M ------LGGAGGDGG------------------LGGNGGVGGDGAQG--- Mvan_2459|M.vanbaalenii_PYR-1 -----SRTGNGGAGG------------------AAGNGGSGGNG------ MSMEG_0868|M.smegmatis_MC2_155 TYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHR Mflv_5091|M.gilvum_PYR-GCK -----GLGGFGGSGG------------------TGGQGGLGGPGG----- TH_3810|M.thermoresistible__bu ------RAGLGGRGX------------------XXXGGGVGAAVR----- MAB_4284c|M.abscessus_ATCC_199 -------VGVGSHVG------------------GGISESLGGSGS----- MAV_4827|M.avium_104 ---HVPTPGAGTPGGS-----------------GGGHLPFPGAGSTP--- MLBr_01556|M.leprae_Br4923 ---MVDEHGVDIEAALP-----------SSPVQVIGFTSVPGAGDNFLVV * . . Mb3543|M.bovis_AF2122/97 PTGIG-------------------GTGGDGGTGGAAGAGGAGGAAGTGG- Rv3508|M.tuberculosis_H37Rv PTGAG-------------------FAGGAGGTGGAAGAGGAGGATGTGG- MUL_0740|M.ulcerans_Agy99 --------------------------GGNGGRGGSAHASLVG-KAGNGG- MMAR_4270|M.marinum_M ------------------------GLGGNGGVRNSDNLSYDG-IIGNGG- Mvan_2459|M.vanbaalenii_PYR-1 ------------------------ATGGDGGSGGVGGAD----------- MSMEG_0868|M.smegmatis_MC2_155 GGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVA Mflv_5091|M.gilvum_PYR-GCK ------------------------STGGAGGAGGQAGTAGKGGLFGGSGS TH_3810|M.thermoresistible__bu --------------------------SGNGVFSGGGGTPSAG-------- MAB_4284c|M.abscessus_ATCC_199 -------------------------VGGSTAVGGGAHTGVGGGVNTGVG- MAV_4827|M.avium_104 -------------------------GGSGGGHLPTPGAGTPGGGLGGFG- MLBr_01556|M.leprae_Br4923 DEDRIAR----------------QIADRRSARKRNALAARSRKRISLEDL . Mb3543|M.bovis_AF2122/97 -----TGGMIGTTGNAGVGGAGGQGGDGG--------------------- Rv3508|M.tuberculosis_H37Rv -----TGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQG MUL_0740|M.ulcerans_Agy99 -----FGGTGGNS-FGGVSGNGGNGGDGG--------------------- MMAR_4270|M.marinum_M -----TGGNGGVGGHGGDGGAGGEGGSGS--------------------- Mvan_2459|M.vanbaalenii_PYR-1 -----VSDPGSGPVTAGTGG---NGGSGG--------------------- MSMEG_0868|M.smegmatis_MC2_155 YNVVQANPQASGTATDGHGGSGINGGHGGNGG------------------ Mflv_5091|M.gilvum_PYR-GCK AG--KAGATGAAGASGGKGAQGATGAQGATGA------------------ TH_3810|M.thermoresistible__bu -----FGVPTTIQFPAGSCTSRAVSREGI--------------------- MAB_4284c|M.abscessus_ATCC_199 -----VGSHVGGGISESLGGSGSVGGSTAVG------------------- MAV_4827|M.avium_104 ------GGHAPAPGGGLGGGGGHAPAPGG--------------------- MLBr_01556|M.leprae_Br4923 DSALKETSQLNLILKGDNAGTVEALEEALMG------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GAGGSAGAGGINGAGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAA MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ---------------------------AGGAGADADQ------------- Rv3508|M.tuberculosis_H37Rv GNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQG MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -----------------------------------------PGATGG--- Rv3508|M.tuberculosis_H37Rv GQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGG MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ----------------------------------------TGFAGGAG-- Rv3508|M.tuberculosis_H37Rv DAGSGGGGGFGGAAGKAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQG-- MUL_0740|M.ulcerans_Agy99 ----------------------------------------HALHGQPG-- MMAR_4270|M.marinum_M ----------------------------------------LLGAAGSA-- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------------QGTIEANGPS Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------QGATGATG-- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------------------------IQVDDEVA Mb3543|M.bovis_AF2122/97 ------GAGGAGGSSGAGGTNGSGGAGG---------------------- Rv3508|M.tuberculosis_H37Rv ------GQGGAGGSAGAGGINGAGGAGGNGGDGGDGATGAAGLGDNGGVG MUL_0740|M.ulcerans_Agy99 ------GHGGQGGHGGVAHIDGSDYPGWP--------------------- MMAR_4270|M.marinum_M ------GSNAAGGSGGTGGLRGQG-------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------AGGAGGDGGAGGLGGKGG------------------------- MSMEG_0868|M.smegmatis_MC2_155 AVASGIGAGGNGGDGIDGGLGGNGGDGVV--------------------- Mflv_5091|M.gilvum_PYR-GCK ------AAGKAGATGAAGAAGAAGSAG----------------------- TH_3810|M.thermoresistible__bu ------MPSSRAASARAGAACASS-------------------------- MAB_4284c|M.abscessus_ATCC_199 --------GGAHTSAINDALGGSGSVGG---------------------- MAV_4827|M.avium_104 ------GLGGFGGGHSGGGLGGLGGGHK---------------------- MLBr_01556|M.leprae_Br4923 LRVIDRGVGGITETNVNLASASDAIIIG---------------------- . . Mb3543|M.bovis_AF2122/97 ------------------------------TGGQGGAGGAG--------- Rv3508|M.tuberculosis_H37Rv GDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNG MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ---------------------ISFSNGS--NGGTGGTGGVG--------- Rv3508|M.tuberculosis_H37Rv GQGGAGGQGGQGGLGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGG MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -----------------NTTANAANPGSATGTATGGDGGKA--------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv SGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLS MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGPDGGD MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 --------------------GTGGDGGNAG---------TGAGDPGKGGT Rv3508|M.tuberculosis_H37Rv GGQGGIGGDGGNAGFGAGVPGDGGDGGNAG---------FGAGVPGDGGI MUL_0740|M.ulcerans_Agy99 -----------------------GLPGDVG---------YQDG---TGGG MMAR_4270|M.marinum_M -----------------------GDPGSTGR--------AGTGSAGADGM Mvan_2459|M.vanbaalenii_PYR-1 ----------------------------------------------AGSS MSMEG_0868|M.smegmatis_MC2_155 -------------------TGTASQGGNGGPSWVQSGYGSTLGGNATGTA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------------TTGA TH_3810|M.thermoresistible__bu ----------------------------------------------TSRS MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------------STAV MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ---------------------------------------------FNVRA Mb3543|M.bovis_AF2122/97 GGTGGSGGAGGS------------GGAN---------------------- Rv3508|M.tuberculosis_H37Rv GGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASG MUL_0740|M.ulcerans_Agy99 GGTGGAGGHAP--------------------------------------- MMAR_4270|M.marinum_M NGTDGDPGDPGGMA------------------------------------ Mvan_2459|M.vanbaalenii_PYR-1 EGSAGADAANG--------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TAGKGGEASNGGVAGNGGNALVMAAGTTGVAT------------------ Mflv_5091|M.gilvum_PYR-GCK QGSAGTNGANG--------------------------------------- TH_3810|M.thermoresistible__bu RRSFCCSRA----------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGGAHTSAINESMN------------------------------------ MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 EGKATELASREGVEIR---------------------------------- Mb3543|M.bovis_AF2122/97 -------------------FNGGTGGTGGTG------------------- Rv3508|M.tuberculosis_H37Rv DGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAG MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 ----------------------ATG------------------------- MSMEG_0868|M.smegmatis_MC2_155 ------GNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHG Mflv_5091|M.gilvum_PYR-GCK ----------------------ANGSQG---------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------G Rv3508|M.tuberculosis_H37Rv IGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGG MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 G------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 TGGKGGMGG----------------------------------------- Rv3508|M.tuberculosis_H37Rv TGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVP MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLA MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------IAGDGGPGGDGGNAGVG-------- Rv3508|M.tuberculosis_H37Rv SAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGT MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 --------------------------AGNGGNGGKGADGWVQAYDPAGPV Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv AGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGI MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GSKIANSSA----------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv NGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGF MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3508|M.tuberculosis_H37Rv GAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLN MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ---------------------------------GKGGTNGNGGSGGTGGT Rv3508|M.tuberculosis_H37Rv STGLASAASGDGGNGGAGGAGGNGGAGGLGGGGGTGGTNGNGGLGGGGGN MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 -------------------------------VGGSGGAGGRGGTGGASG- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------VAGNGGDGGVNGTGGASGG Mflv_5091|M.gilvum_PYR-GCK -------------------------------AAGKAGATGTTGATGAAGE TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------SSINASHSSSMNESFGSSMGS MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------YYLVIYQAIDDIEKALRGMLKPIYEE Mb3543|M.bovis_AF2122/97 GGPGGSGGAPTGSGTGGKGGAGGDGGDGADGGAATG--VGDGGDGGNGGN Rv3508|M.tuberculosis_H37Rv GGAGGAGGTPTGSGTEGTGGDGGDAGAGGNGGSATG--VGNGGNGGDGGN MUL_0740|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4270|M.marinum_M -------------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 DGASGG------SGG---AGKPGTGPTGSKGG-----------AGGSGGS MSMEG_0868|M.smegmatis_MC2_155 DGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGN Mflv_5091|M.gilvum_PYR-GCK DGDAGSGGSGINGGAGGAGGAGGEGGEGGDGGKG-----GAGAEGGAGGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 HGAAGTGFEAQGHAQGHASETAHTTLPGAEHH------------------ MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 NQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLT Mb3543|M.bovis_AF2122/97 GGNGGTGVGSPGGLGGAGGTGGLGGAGAGGGADGDDGDDGQPGNNGS Rv3508|M.tuberculosis_H37Rv GGDGGN--GAPGGFGGGAGAGGLGGSGAGGGTDGDDGNGGSPGTDGS MUL_0740|M.ulcerans_Agy99 ----------------------------------------------- MMAR_4270|M.marinum_M ----------------------------------------------- Mvan_2459|M.vanbaalenii_PYR-1 GGSGGQAD--------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP------- Mflv_5091|M.gilvum_PYR-GCK GGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD------- TH_3810|M.thermoresistible__bu ----------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------------- MAV_4827|M.avium_104 ----------------------------------------------- MLBr_01556|M.leprae_Br4923 VTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA-