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MSFVVTAPPVLASAASDLGGIASMISEANAMAAVRTTALAPAAADEVSAAIAALFSSYARDYQTLSVQVT AFHVQFAQTLTNAGQLYAVVDVGNGVLLKTEQQVLGVINAPTQTLVGRPLIGDGTHGAPGTGQNGGAGGI LWGNGGNGGSGAPGQPGGRGGDAGLFGHGGHGGVGGPGIAGAAGTAGLPGGNGANGGSGGIGGAGGAGGN GGLLFGNGGAGGQGGSGGLGGSGGTGGAGMAAGPAGGTGGIGGIGGIGGAGGVGGHGSALFGHGGINGDG GTGGMGGQGGAGGNGWAAEGITVGIGEQGGQGGDGGAGGAGGIGGSAGGIGGSQGAGGHGGDGGQGGAGG SGGVGGGGAGAGGDGGAGGIGGTGGNGSIGGAAGNGGNGGRGGAGGMATAGSDGGNGGGGGNGGVGVGSA GGAGGTGGDGGAAGAGGAPGHGYFQQPAPQGLPIGTGGTGGEGGAGGAGGDGGQGDIGFDGGRGGDGGPG GGGGAGGDGSGTFNAQANNGGDGGAGGVGGAGGTGGTGGVGADGGRGGDSGRGGDGGNAGHGGAAQFSGR GAYGGEGGSGGAGGNAGGAGTGGTAGSGGAGGFGGNGADGGNGGNGGNGGFGGINGTFGTNGAGGTGGLG TLLGGHNGNIGLNGATGGIGSTTLTNATVPLQLVNTTEPVVFISLNGGQMVPVLLDTGSTGLVMDSQFLT QNFGPVIGTGTAGYAGGLTYNYNTYSTTVDFGNGLLTLPTSVNVVTSSSPGTLGNFLSRSGAVGVLGIGP NNGFPGTSSIVTAMPGLLNNGVLIDESAGILQFGPNTLTGGITISGAPISTVAVQIDNGPLQQAPVMFDS GGINGTIPSALASLPSGGFVPAGTTISVYTSDGQTLLYSYTTTATNTPFVTSGGVMNTGHVPFAQQPIYV SYSPTAIGTTTFN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0977 | PE_PGRS16 | - | 100% (923) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv0578c | PE_PGRS7 | 0.0 | 49.80% (757) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3345c | PE_PGRS50 | 0.0 | 46.79% (887) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1002 | PE_PGRS16 | 0.0 | 100.00% (923) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-143 | 52.09% (551) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 3e-10 | 35.87% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-47 | 33.73% (424) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2033 | - | 0.0 | 46.90% (872) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-24 | 44.24% (165) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-115 | 38.18% (935) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-44 | 42.24% (303) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 1e-171 | 43.14% (925) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-141 | 48.99% (592) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Rv0977|M.tuberculosis_H37Rv --------------------------------------------------
Mb1002|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Rv0977|M.tuberculosis_H37Rv --------------------MSFVVTAPPVLASAASDLGGIASMISEAN-
Mb1002|M.bovis_AF2122/97 --------------------MSFVVTAPPVLASAASDLGGIASMISEAN-
MLBr_01183|M.leprae_Br4923 -------------------MPLFLNAEPQALTAAANTLEGLSAATVASN-
MMAR_2033|M.marinum_M --------------------MSYLAIAPEIVAAAAADMDGIGSAITAAN-
MUL_4367|M.ulcerans_Agy99 --------------------MSFVSVGPGLLEAAARDLAGLGAGLREAN-
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------MSIIDFILNLFRDPVEAASYVADPEAALANAG-
MAV_4827|M.avium_104 -----------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEED-
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Rv0977|M.tuberculosis_H37Rv ------------------------------------AMAAVRTTALAPAA
Mb1002|M.bovis_AF2122/97 ------------------------------------AMAAVRTTALAPAA
MLBr_01183|M.leprae_Br4923 ------------------------------------AAAAQLTTEIAPPA
MMAR_2033|M.marinum_M ------------------------------------AAAAIPTSAIAAAA
MUL_4367|M.ulcerans_Agy99 ------------------------------------LAAAGATVGVLPAA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------LSAVSAAQVGAVMPVV
MAV_4827|M.avium_104 -----------------------------------AIDVTGADDAATASA
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Rv0977|M.tuberculosis_H37Rv ADEVS-----------------------------------AAIAALFSSY
Mb1002|M.bovis_AF2122/97 ADEVS-----------------------------------AAIAALFSSY
MLBr_01183|M.leprae_Br4923 ADDVS-----------------------------------ILLAHFFSGH
MMAR_2033|M.marinum_M ADEIS-----------------------------------AAIAELFGNH
MUL_4367|M.ulcerans_Agy99 GDEVS-----------------------------------AAIAELFGGF
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AESVASN---------------------------------YGYQSQWVNT
MAV_4827|M.avium_104 PDRVIS-----------------------------------AILGTREGA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Rv0977|M.tuberculosis_H37Rv ARDYQTLSVQVTAFHVQFAQTLTNAGQLYAVVDVGNGV-LLKTEQQVLGV
Mb1002|M.bovis_AF2122/97 ARDYQTLSVQVTAFHVQFAQTLTNAGQLYAVVDVGNGV-LLKTEQQVLGV
MLBr_01183|M.leprae_Br4923 GRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN--------HDSL--
MMAR_2033|M.marinum_M AQQYQALSAQIARFHDQFVRSLSGAAQTYASAEATG----AAPLQPVLDL
MUL_4367|M.ulcerans_Agy99 GREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDND---FLSHNDTDFAS
MAV_4827|M.avium_104 ADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQN
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Rv0977|M.tuberculosis_H37Rv IN---APTQTLVGRPLIGDGTHGAPGTGQNGGAGGILWGNGGNGGSGAPG
Mb1002|M.bovis_AF2122/97 IN---APTQTLVGRPLIGDGTHGAPGTGQNGGAGGILWGNGGNGGSGAPG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M IN---GPTQALLGRPLIGNGASGAPGTGQAGGDGGLLIGNGGAGGSGAAG
MUL_4367|M.ulcerans_Agy99 VN---APSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGNGGNGGLGAAG
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGD-----
MAB_4284c|M.abscessus_ATCC_199 HN-----------PIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRD
MAV_4827|M.avium_104 VG------------GAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQ
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGN---------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGR---------------------------------
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGI---------------------------------
Rv0977|M.tuberculosis_H37Rv QPGGRGGDAGLFG-------------------------------------
Mb1002|M.bovis_AF2122/97 QPGGRGGDAGLFG-------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M QAGGAGGAAGLIGSGGAGGIGGTGAAGGKGGNAVLFGAGGNGGIGGTGAV
MUL_4367|M.ulcerans_Agy99 ANGGAGGSAGLIG-------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TTAIGDGAVAVG--------------------------------------
MAV_4827|M.avium_104 QIRAES--------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------GGNGGNGGVGVVGATGAVG--APGVAG--AT
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GGNGGNGGVGIAGATGAVG--APGVAG--AT
MSMEG_0868|M.smegmatis_MC2_155 -------------------GGAGGAGGVGADGTSAHVDGGTGGTGG--TG
Rv0977|M.tuberculosis_H37Rv ------------------HGGHGGVGGPGIAGAAGTAGLPGGNG----AN
Mb1002|M.bovis_AF2122/97 ------------------HGGHGGVGGPGIAGAAGTAGLPGGNG----AN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GGTGAAGGAGGNGGFLFGHGGDGGTGGTGASGVAGANGGAGQTG----LA
MUL_4367|M.ulcerans_Agy99 ------------------TGGVGGAGGVGAAGMTGGSGGAGGGGGWLWGA
TH_3810|M.thermoresistible__bu -------------------GGDGGLGGNGGHG------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------GSNSGPIASGQGSTAVNGDVRDSNIINADHG
MAV_4827|M.avium_104 ---------------------YGDAAGQLSAMVAGLEKLESLPGGLLLVG
Mflv_5091|M.gilvum_PYR-GCK GATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-----------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAG
Rv0977|M.tuberculosis_H37Rv GGSGGIGGAGGAGGNGGLLFGNGGAGGQGGSGGLGGSGG-----------
Mb1002|M.bovis_AF2122/97 GGSGGIGGAGGAGGNGGLLFGNGGAGGQGGSGGLGGSGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GTDGGTGGVGGAGGKGGLLFGAGGEGGAGGTGGAGGAGG-----------
MUL_4367|M.ulcerans_Agy99 GGSGGAAGAGGSGGSGGWLWGNAGQTAGAGVGGAGGAGG-----------
TH_3810|M.thermoresistible__bu GGTGIISLLSLAGNGGNGGNGYRTTDNNALDGGHGGNGG-----------
MAB_4284c|M.abscessus_ATCC_199 SNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQ-----------
MAV_4827|M.avium_104 SGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAA-----------
Mflv_5091|M.gilvum_PYR-GCK ---AVGSAGAAGEAGETG--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---AVGSAGTAGSAGAPG--------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PNVTVGSETRGGTGGAGG--------------------------------
Rv0977|M.tuberculosis_H37Rv ---TGGAGMAAGPAGGTG--------------------------------
Mb1002|M.bovis_AF2122/97 ---TGGAGMAAGPAGGTG--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M ---TGGDGLAATTAGGTGGNAGDGGGGGTGGNAGDGGAGGQGGLFGNAGT
MUL_4367|M.ulcerans_Agy99 ---AGDAGDQGVSGVAPG--------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----TWG--NAGLPGKAGDAGGAG----------------AVGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 -----VWG--NAGLPGAAGAAGGAG----------------AIGTAGVAG
MSMEG_0868|M.smegmatis_MC2_155 -----TGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNGGNG
Rv0977|M.tuberculosis_H37Rv -------GIGGIGGIGGAGGVGGHGS---------------ALFGHGGIN
Mb1002|M.bovis_AF2122/97 -------GIGGIGGIGGAGGVGGHGS---------------ALFGHGGIN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M TGAGGDGGNGGNGGLAGNGGAGGNGD---------------ASNPNGGTG
MUL_4367|M.ulcerans_Agy99 -------EAGAVGFAGGAGGAGGAGG---------------NGVG-GGVN
TH_3810|M.thermoresistible__bu --------NVGFFSLFNLGGAGGWGG------------------------
MAB_4284c|M.abscessus_ATCC_199 ------RNTTNINDSFNTDRSTNIGS------------------------
MAV_4827|M.avium_104 ----------NAPLFASSTAALAYAQ------------------------
Mflv_5091|M.gilvum_PYR-GCK ------TVGTAGATGGTG--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------AAGTAGATGGTG--------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GNGSTTAAGGNGGTGGTGRVIAE---------------------------
Rv0977|M.tuberculosis_H37Rv GDGGTGGMGGQGGAGGNG--------------------------------
Mb1002|M.bovis_AF2122/97 GDGGTGGMGGQGGAGGNG--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GNGANPGAGGAGGAGGNGSRTGAPGTTGNTPTTAAGHGGKGGDGFSPATS
MUL_4367|M.ulcerans_Agy99 GAGGAGGAGGVGGGGGAG--------------------------------
TH_3810|M.thermoresistible__bu -----SGVDGVDVVGGNP--------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------GNTTNTEIGSHN--------------------------------
MAV_4827|M.avium_104 -------DPGTGAVDQYS--------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------------------------TGANGGAGGVGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------VGGNGGAGQAGGIGG
MSMEG_0868|M.smegmatis_MC2_155 -------------------------GTGSTAEGTATGGDGGHSTGTGIGG
Rv0977|M.tuberculosis_H37Rv --------------------------WAAEGITVGIGEQGGQGGDGGAGG
Mb1002|M.bovis_AF2122/97 --------------------------WAAEGITVGIGEQGGQGGDGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GQDGGSGGKGGDAGRFGNGGNGGNGGNGAAGDAAGSGHTGGNGGAGGGGG
MUL_4367|M.ulcerans_Agy99 ------------------------------ASGVGAGVAGGDGGTGGAGG
TH_3810|M.thermoresistible__bu --------------------------------------DGGTPGAHGESH
MAB_4284c|M.abscessus_ATCC_199 --------------------------------QANIGTSTSAGGSAAVGG
MAV_4827|M.avium_104 -----------------------------------LPDYLYVPVDPEPGD
Mflv_5091|M.gilvum_PYR-GCK TGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ--------
Mvan_1264|M.vanbaalenii_PYR-1 TGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ--------
MSMEG_0868|M.smegmatis_MC2_155 NGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIYS------
Rv0977|M.tuberculosis_H37Rv AGGIGG--SAGGIGG--SQGAGGHGGDGGQGGAGGSGGVGGGG-------
Mb1002|M.bovis_AF2122/97 AGGIGG--SAGGIGG--SQGAGGHGGDGGQGGAGGSGGVGGGG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M NAGQFGEPGTGGSGG--NGGKGGDGAAGGLAQAGGNGGEGGAGGNAGAGG
MUL_4367|M.ulcerans_Agy99 AAGVGGAAGTGGTGG--AAGVAGTGGDGGDGGAGGAGSDASLAG------
TH_3810|M.thermoresistible__bu TPGVYT---------------DRQGEDGEDGTGTGIGG------------
MAB_4284c|M.abscessus_ATCC_199 NAGLAG-------------NAGLAGNAGLAGNAGLAGNAGLAGN------
MAV_4827|M.avium_104 DELAYS----------------AVGEEDAESPTVVIEKLFLPED------
Mflv_5091|M.gilvum_PYR-GCK ----------GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--
Mvan_1264|M.vanbaalenii_PYR-1 ----------GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--
MSMEG_0868|M.smegmatis_MC2_155 ----------GADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPT
Rv0977|M.tuberculosis_H37Rv ----------AGAGGDGGAGGIGGTGGNGSIGGAAGNGG----NGGRGGA
Mb1002|M.bovis_AF2122/97 ----------AGAGGDGGAGGIGGTGGNGSIGGAAGNGG----NGGRGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M LSGTGDSTGNAGTGGNGGAGGNGGTGGDGSDGGPGGAGG----KGGNSGP
MUL_4367|M.ulcerans_Agy99 --------QAGFAGGSGGAGGVGGSAGAGGVNGSGGDGG----AGAAGGA
TH_3810|M.thermoresistible__bu ------------RGGNGGSSSGTHPMAEDGEHVKALDGR-----------
MAB_4284c|M.abscessus_ATCC_199 ----------AGLAGNAGLAGNAGLAGNAGLAGNAGLAG-----------
MAV_4827|M.avium_104 -----------SEPRRRPVLLVGSGLAVVGISAVLALEI-----------
Mflv_5091|M.gilvum_PYR-GCK -----------LQGGKGGDGG------AGGKGGDADSMGS----------
Mvan_1264|M.vanbaalenii_PYR-1 -----------LQGGQGGDGG------TGGTGGDATSMGE----------
MSMEG_0868|M.smegmatis_MC2_155 TGGKASGTAKAGHGGKASDGG------KGGNGGDALVMAAGATGVATGNT
Rv0977|M.tuberculosis_H37Rv G-GMATAGSDGGNGGGGGNGG-----VGVGSAGGAGGTGGDGGAAGAGGA
Mb1002|M.bovis_AF2122/97 G-GMATAGSDGGNGGGGGNGG-----VGVGSAGGAGGTGGDGGAAGAGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M G-GTNGTGGHGGNGGTGGDGGDGASGVGLGKAGGTGATGGNGGNAGSGGA
MUL_4367|M.ulcerans_Agy99 GGASATVAGSGGVGGDGGAGG------AAGGGVGAASLGGDGGHAGAGGA
TH_3810|M.thermoresistible__bu ------------PGLDGGNGS-----------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAG-----------------------------
MAV_4827|M.avium_104 ----------ALAIGIRTTG------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------AGATGGKGGNGGNGGRGGLFG---------------KGGNAG
Mvan_1264|M.vanbaalenii_PYR-1 --------AGATGGKGGNGGNGGRGSLFG---------------RGGNAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGG
Rv0977|M.tuberculosis_H37Rv PGHGYFQQPAPQGLPIGTGGTGGEGGAG---------------GAGGDGG
Mb1002|M.bovis_AF2122/97 PGHGYFQQPAPQGLPIGTGGTGGEGGAG---------------GAGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M AGTGGTGGTNGSAGTGGTGGTGGNGGAGDKGAVGDSGFAGGTGGAGGTGG
MUL_4367|M.ulcerans_Agy99 GGEGLSGGFN-TGAAGGIGGAGGAGGTG-----------GDSGGVGGVNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAGLAGNAGLAG---------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK NGAD----------------------GGTGGAGGA---------------
Mvan_1264|M.vanbaalenii_PYR-1 NGGN----------------------GGTGGNGGN---------------
MSMEG_0868|M.smegmatis_MC2_155 NGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGF---------------
Rv0977|M.tuberculosis_H37Rv QGDIGFDGGRGGDGGP-------GGGGGAGGDGS----------------
Mb1002|M.bovis_AF2122/97 QGDIGFDGGRGGDGGP-------GGGGGAGGDGS----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M NSGPGGTNGTGGHGGN-------GGTGGDGGDGASGVGQGKAGGTGATGG
MUL_4367|M.ulcerans_Agy99 DGGAGGGGGRGGDGGSSTSTSGVGGAGGAGGNGGNAGFGVSAGGTGGSAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------GGTGG-TGGAGGTGG----------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GGTGG-TGGNGGTGG----------------
MSMEG_0868|M.smegmatis_MC2_155 -------------------NGTGGATGGRGGDGAGASVWKANGQHSTGQT
Rv0977|M.tuberculosis_H37Rv -------------------GTFNAQANNGGDGGAGGVGG-----------
Mb1002|M.bovis_AF2122/97 -------------------GTFNAQANNGGDGGAGGVGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M NGGNAGSGGAAGTGGDASGGGTNGSAGTGGTGGTGGNGGDGDKGAVGDSG
MUL_4367|M.ulcerans_Agy99 DGGAGGGAGG--------VDGVGGASGNGGAAGAGGAGGSGIG--AGIDG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG----------------G
Mvan_1264|M.vanbaalenii_PYR-1 -TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG----------------G
MSMEG_0868|M.smegmatis_MC2_155 DTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE---------------G
Rv0977|M.tuberculosis_H37Rv -AGGTGGTGGVGADGGRGGDSGRGGDGGNAGHGG-------------AAQ
Mb1002|M.bovis_AF2122/97 -AGGTGGTGGVGADGGRGGDSGRGGDGGNAGHGG-------------AAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M FAGGTGGAGGTGGNSGPGGTNGTGGHGGNGGTGGDGGDGASGVGQGKAGG
MUL_4367|M.ulcerans_Agy99 GAGGAGGTGGAAGFPGGGGTTGAWGTGGAGGAGGAGGAGDHGGVGVNPGD
TH_3810|M.thermoresistible__bu -HGGNGGHGGRGGFLGIGGSGGWGGHGGN---------------------
MAB_4284c|M.abscessus_ATCC_199 -NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG----------------
MAV_4827|M.avium_104 -TVALQPTPNQHLIVPTEQAPAPPPVQASAPQPK---------------I
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 EGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVD
Rv0977|M.tuberculosis_H37Rv FSGRGAYGGEGGSGGAGGNAGGAGTGG-TAGSGGAGGFGGNGADG-----
Mb1002|M.bovis_AF2122/97 FSGRGAYGGEGGSGGAGGNAGGAGTGG-TAGSGGAGGFGGNGADG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M TGATGGSGGNAGSGGAAGTGGNGGTNG-NAGTGGTGGTGGNGGDGDKGAV
MUL_4367|M.ulcerans_Agy99 SGTAGWAGGAGGAGGAGGSAAFNGVNG-AGGAGGNGGAGGGGGAGASGIG
TH_3810|M.thermoresistible__bu GGDTDADGGNGGDGGNGGSAGRGGTGG---LRGVFGINGGNGRAG-----
MAB_4284c|M.abscessus_ATCC_199 LAGNAAVAGNAAVAGNAAVAGNAAVGG-VLNTGVSGAIGGSSHVG-----
MAV_4827|M.avium_104 SVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVP-----
Mflv_5091|M.gilvum_PYR-GCK ----------GTGGTGGTGGAG-----------DGTGGTGGTGG----TG
Mvan_1264|M.vanbaalenii_PYR-1 ----------GTGGTGGTGGAG-----------DGLGGTGGTGG----TG
MSMEG_0868|M.smegmatis_MC2_155 ------PSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADG
Rv0977|M.tuberculosis_H37Rv ----------GNGGNGGNGGFGGINGTFGTNGAGGTGG-LGTLLGG-HNG
Mb1002|M.bovis_AF2122/97 ----------GNGGNGGNGGFGGINGTFGTNGAGGTGG-LGTLLGG-HNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GDSGFAGGTGGNGGTGGNSGPGGTNGTGGHGGNGGTGGDGGDGRNG-STG
MUL_4367|M.ulcerans_Agy99 -----AGVAGGDGGTGGTGGAAGTGGAAGTGGTGGAAGAAGSAGDG-GAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------GAINE
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 GFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 HRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATI
Rv0977|M.tuberculosis_H37Rv NIGLNGATGGIGSTTLTNATVPLQLVNTTEP-VVFISLNGGQMVPVLLD-
Mb1002|M.bovis_AF2122/97 NIGLNGATGGIGSTTLTNATVPLQLVNTTEP-VVFISLNGGQMVPVLLD-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M AIGGNGGTGGTGGIGGTAGTGGTGGSAGSAG-TGGTGGNGGAGDSGASGG
MUL_4367|M.ulcerans_Agy99 GAGGAGDDGSAGVVSGDPGTAGKAGGAGGAGGVGGNGVAGGVNGSGGAGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SLGGSGSVGG----------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------------GQGGTGGTGGQGGTGGTGGTGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTGGTGGTGGQGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 VAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGI
Rv0977|M.tuberculosis_H37Rv -------------------------TGSTGLVMDSQFLTQNFG-------
Mb1002|M.bovis_AF2122/97 -------------------------TGSTGLVMDSQFLTQNFG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M TGGTGGEGGAGIGGKDGGT-GGTGGTGGTGGAGVVSGLSAFPG-------
MUL_4367|M.ulcerans_Agy99 AGGAGGTGGAGASGVPASVDGGDGGAGGAGGAAGTGGSGGSAGNT-----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------STAVGGGAHTGVGGGVSTGVG-------
MAV_4827|M.avium_104 ----------------------VPVVVPPVPVPVPVRIPVPDP-------
Mflv_5091|M.gilvum_PYR-GCK GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGT
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGV
MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGT
Rv0977|M.tuberculosis_H37Rv PVIGTGTAGYAGGLTYNYNTYSTTVDFGNGLLTLPTSVNVVTSSSPGT--
Mb1002|M.bovis_AF2122/97 PVIGTGTAGYAGGLTYNYNTYSTTVDFGNGLLTLPTSVNVVTSSSPGT--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GIGGAGGAGGQGGQATGGGNAGDGGTGGQGGTGGQGATSLFEASSGGTGG
MUL_4367|M.ulcerans_Agy99 GAGGAGGAGGAGGSAASTGVNGDGGAGGAGGVGGLGGDSAATAGGGGAGG
TH_3810|M.thermoresistible__bu -LGGRGXXXXGGGVGAAVRSGNGVFSGGGGTPSAGFGVPTTIQFPAGSCT
MAB_4284c|M.abscessus_ATCC_199 -VGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG
MAV_4827|M.avium_104 VSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGE
Mflv_5091|M.gilvum_PYR-GCK AGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG-----
Mvan_1264|M.vanbaalenii_PYR-1 AGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG-----
MSMEG_0868|M.smegmatis_MC2_155 ASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALV
Rv0977|M.tuberculosis_H37Rv ------LGNFLSRSGAVGVLGIGPNNGFPGTSSIVTAMPGLLNNG-----
Mb1002|M.bovis_AF2122/97 ------LGNFLSRSGAVGVLGIGPNNGFPGTSSIVTAMPGLLNNG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M AGGAGGLGGQAADGGNAGDGGTGGQGGTGGQGAAGPTVNDTAGDGGAGGD
MUL_4367|M.ulcerans_Agy99 DGGKGGAGGAGVNGVGGGDGGKGGTGGAGGAGGAGSDG-IIPSNGGLGGN
TH_3810|M.thermoresistible__bu SRAVSREGIMPSSRAASARAGAACASSTSRSRRSFCCSRA----------
MAB_4284c|M.abscessus_ATCC_199 GISESLGGS--GSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGG-----
MAV_4827|M.avium_104 GTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPGAGGSGGSG-----
Mflv_5091|M.gilvum_PYR-GCK -AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGS
Mvan_1264|M.vanbaalenii_PYR-1 -AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGS
MSMEG_0868|M.smegmatis_MC2_155 MAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAI
Rv0977|M.tuberculosis_H37Rv ------------VLIDESAGILQFGPNTLTGG----------ITISGAPI
Mb1002|M.bovis_AF2122/97 ------------VLIDESAGILQFGPNTLTGG----------ITISGAPI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GGVGGAGGQGGQATDGGNAGNAGDGGNGGQGG----------TGGQGAAA
MUL_4367|M.ulcerans_Agy99 GGNGGNGGQAFGDGVGGAGGIGGKGGNAAIGT----------IVINGG-V
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------ISESLGGSGSVGGSTAVGG--------------GAHT
MAV_4827|M.avium_104 ------------GGHVPTPGTGGPGGTGGSGG-------------GHVPT
Mflv_5091|M.gilvum_PYR-GCK AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGG
Mvan_1264|M.vanbaalenii_PYR-1 AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEA
MSMEG_0868|M.smegmatis_MC2_155 SGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG
Rv0977|M.tuberculosis_H37Rv STVAVQIDNGPLQQAP------------------VMFDSGGINGTIPSAL
Mb1002|M.bovis_AF2122/97 STVAVQIDNGPLQQAP------------------VMFDSGGINGTIPSAL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M PSAAKAAGNGGAGGVGGDGGNGADASGGGNGGDGGKSGGGGTGGTGGKSL
MUL_4367|M.ulcerans_Agy99 GGAGGSGGLGGATEDGVGGVGCAGGAGGNGGRGDMLFTVGGSGGTGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SAINDALGGSGS--------------------------VGGSTAVGGGAH
MAV_4827|M.avium_104 PGAGTPGGSGGGHLPFP----------------------GAGSTPGGSGG
Mflv_5091|M.gilvum_PYR-GCK SG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE-------
Mvan_1264|M.vanbaalenii_PYR-1 VD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE-------
MSMEG_0868|M.smegmatis_MC2_155 TGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNG
Rv0977|M.tuberculosis_H37Rv ASLPSGGFVPAGTTISVYTSDGQTLLYSYTTTATNTPFVTSG--------
Mb1002|M.bovis_AF2122/97 ASLPSGGFVPAGTTISVYTSDGQTLLYSYTTTATNTPFVTSG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M GNLPSGDGGVGGNAGTGGNGGNATDGGAGGKGGDGAAGGTGGNAGEFQSL
MUL_4367|M.ulcerans_Agy99 GGGSASGSGTGGSGGTGGVGGIGGDGKLGGFGGDGGDGGDGG--------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAINESMN-------------SSINASHSSSMNESFGSSMG--------
MAV_4827|M.avium_104 GHLPTPGAGTPGG-------------GLGGFGGGHAPAPGGG--------
Mflv_5091|M.gilvum_PYR-GCK -GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1 -GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD----
MSMEG_0868|M.smegmatis_MC2_155 AGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP---
Rv0977|M.tuberculosis_H37Rv ---------GVMNTGHVPFAQQPIYVSYSPTAIGTTTFN-----------
Mb1002|M.bovis_AF2122/97 ---------GVMNTGHVPFAQQPIYVSYSPTAIGTTTFN-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_2033|M.marinum_M LGIGKGGDGGTGGDGGNGGTGTPVGAGGLAGTGGAGGFGVFPGGQTGQNG
MUL_4367|M.ulcerans_Agy99 --------FGVIGGQGGGGGFGGLGGTGAGGAPSDKGINGEPGNPG----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------SHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH------
MAV_4827|M.avium_104 -----------LGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK----
Mflv_5091|M.gilvum_PYR-GCK ------
Mvan_1264|M.vanbaalenii_PYR-1 ------
MSMEG_0868|M.smegmatis_MC2_155 ------
Rv0977|M.tuberculosis_H37Rv ------
Mb1002|M.bovis_AF2122/97 ------
MLBr_01183|M.leprae_Br4923 ------
MMAR_2033|M.marinum_M TDGKAG
MUL_4367|M.ulcerans_Agy99 ------
TH_3810|M.thermoresistible__bu ------
MAB_4284c|M.abscessus_ATCC_199 ------
MAV_4827|M.avium_104 ------