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M. bovis AF2122 / 97 Mb3402 (PE_PGRS51)

annotation: PE-PGRS family protein
coordinates: 3732094 - 3733974
length: 626

MSFVVAVPEALAAAASDVANIGSALSAANAAAAAGTTGLLAAGADEVSAALASLFSGHAVSYQQVAAQAT
ALHDQFVQALTGAGGSYALTEAANVQQNLLNAINAPTQALLGRPLIGDGAVGTASSPDGQDGGLLFGNGG
AGYNSAATPGMAGGNGGNAGLIGNGGTGGSGGAGAAGGAGGSGGWLYGNGGNGGIGGNAIVAGGAGGNGG
AGGAAGLWGSGGSGGQGGNGLTGNDGVNPAPVTNPALNGAAGDSNIEPQTSVLIGTQGGDGTPGGAGVNG
GNGGAGGDANGNPANTSIANAGAGGNGAAGGDGGANGGAGGAGGQAASAGSSVGGDGGNGGAGGTGTNGH
AGGAGGAGGQAASAGSSVGGDGGNGGAGGTGTNGHAGGAGGAGGAGGRGGWLVGSGGNGGNGGNGAAGGN
GAIGGTGGAGGVPANQGGNSALGTQPVSGDGGDGGNGGTGGTGGRGGDGGSGGAGGASGWLMGNGGNGGN
GGTGGSGGVGGNGGIGGDGAGGGNATSTSSIPFDAHGGNGGAGGDAGHGGTGGDGGDGGHAGTGGRGGLL
AGQHANSGNGGGGGTGGAGGTHGTPGSGNAGGTGTGNADSTNGGPGSDGLGGDAFNGSRGTDGNPG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3402PE_PGRS51-100% (626)PE-PGRS family protein
M. bovis AF2122 / 97Mb1121PE_PGRS22e-17650.13% (742) PE-PGRS family protein
M. bovis AF2122 / 97Mb2878PE_PGRS48e-17353.70% (635) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5091-1e-12248.11% (555) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3367PE_PGRS510.086.01% (629) PE-PGRS family protein
M. leprae Br4923MLBr_01183-4e-1443.48% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-5034.95% (475) hypothetical protein MAB_4284c
M. marinum MMMAR_1161-0.060.00% (655) PE-PGRS family protein
M. avium 104MAV_1346-5e-2333.33% (300) PE family protein
M. smegmatis MC2 155MSMEG_0868-1e-10240.09% (681) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-1e-4242.14% (299) PUTATIVE -
M. ulcerans Agy99MUL_3507-1e-15551.25% (642) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-12148.99% (547) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1161|M.marinum_M               --------------------------------------------------
MUL_3507|M.ulcerans_Agy99           --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            ----------MSFVVAVPEALAAAASDVANIGSALSAANAAAAAGTTGLL
Rv3367|M.tuberculosis_H37Rv         ----------MSFVVAVPEALAAAASDVANIGSALSAANAAAAAGTTGLL
MMAR_1161|M.marinum_M               ----------MSYVLAAPDAMATAASSVTNIGGALSAANAMATAPTTGVL
MUL_3507|M.ulcerans_Agy99           ----------MSFVSVTQEALAAAASDVGVIGSSLQAANMSVAAPTAGVL
MAB_4284c|M.abscessus_ATCC_199      -------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            AAGADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQALTGAGGSYALT
Rv3367|M.tuberculosis_H37Rv         AAGADEVSAALASLFSGHAVSYQQVAAQATALHDQFVQALTGAGGSYALT
MMAR_1161|M.marinum_M               AAAADEISVAMASVFSDHALSYQQVAARMAAFHDQFVAALHSGAGAYLTA
MUL_3507|M.ulcerans_Agy99           AAGADEVSVAMAALFSGHGQAYQTLSAQANAFHAQFLQALTNAGGAYAAA
MAB_4284c|M.abscessus_ATCC_199      VMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            EAAN--------------------------------------VQQNLLNA
Rv3367|M.tuberculosis_H37Rv         EAAN--------------------------------------VQQNLLNA
MMAR_1161|M.marinum_M               ETANAS--------------------------------PLGTLEQRLLQA
MUL_3507|M.ulcerans_Agy99           EVANLS--------------------------------PLQGVEQGVLGV
MAB_4284c|M.abscessus_ATCC_199      LLSPRD----------------------------NDFLSHNDTDFASHNP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            IN--------------------APTQALLG--------RPLIGDGAVGTA
Rv3367|M.tuberculosis_H37Rv         IN--------------------APTQALLG--------RPLIGDGAVGTA
MMAR_1161|M.marinum_M               IN--------------------APTQTLLG--------RPLIGDGAAGTA
MUL_3507|M.ulcerans_Agy99           VN--------------------APAQALLG--------RPLIGDGAAGTA
MAB_4284c|M.abscessus_ATCC_199      IASGN---------------QVMSPSGNVDSFNRGPLLDLSFGDLQFGNR
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWN--SDVVGMDGGNGGNGGLFGGNGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWN--SEIAGVSGGNGGNAGLFGGNGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYD--GSAAGLAGGNGGNAGLFG-NGGNGGVGW
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            SSPDGQDGGLLFGNGGAGYN-SAATPGMAGGNGGNAGLIG-NGGTGGSGG
Rv3367|M.tuberculosis_H37Rv         SSPDGQDGGLLFGNGGAGYN-SAATPGMAGGNGGNAGLIG-NGGTGGSGG
MMAR_1161|M.marinum_M               TNPNGGAGGLLYGNGGAGFN-NGATAGAAGGNGGNAGLFG-SGGAGGSGG
MUL_3507|M.ulcerans_Agy99           ASPNGGAGGLLYGNGGAGYSYTSGATAEAGGNGGAAGLIG-NGGAGGSGW
MAB_4284c|M.abscessus_ATCC_199      DTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSN-VGV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1       GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155      AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu      VDGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGG
Mb3402|M.bovis_AF2122/97            AGAAGGAGGSGG--WLYGNGGNGGIGGNAIVAG---------GAGGNGGA
Rv3367|M.tuberculosis_H37Rv         AGAAGGAGGSGG--WLYGNGGNGGIGGNAIVAG---------GAGGNGGA
MMAR_1161|M.marinum_M               AGAAGGAGGSGG--WLYGSGGNGGSGGNAVIAG---------GNGGAGGA
MUL_3507|M.ulcerans_Agy99           AGGAGGAGGNGG--WLYGNGGAGGLGGAAAGDY---------TAGGVGGA
MAB_4284c|M.abscessus_ATCC_199      DQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRST
MLBr_01183|M.leprae_Br4923          -------------MPLFLNAEPQALTAAAN------------TLEGLSAA
MAV_1346|M.avium_104                -------------MS-FVTTRPEALLAVAS------------MLEGLGSS
                                                                                    . 

Mflv_5091|M.gilvum_PYR-GCK          TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155      TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu      TGIIS--------------------LLSLAGNGGNGG-------------
Mb3402|M.bovis_AF2122/97            GGAAG--------------------LWGSGGSGGQGG-------------
Rv3367|M.tuberculosis_H37Rv         GGAAG--------------------LWGSGGSGGQGG-------------
MMAR_1161|M.marinum_M               GGAAG--------------------LWGAGGNGGQGG-------------
MUL_3507|M.ulcerans_Agy99           GGNAG--------------------LWGDGGAGGNGSA------TYDYDQ
MAB_4284c|M.abscessus_ATCC_199      NIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAG-------------
MLBr_01183|M.leprae_Br4923          TVASN---------------------------------------------
MAV_1346|M.avium_104                MDAQN---------------------------------------------
                                        .                                             

Mflv_5091|M.gilvum_PYR-GCK          -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1       -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155      VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu      --NGYRTTDNNALDGGHGG-------------------------------
Mb3402|M.bovis_AF2122/97            --NGLTGNDGVNPAPVTNP-------------------------------
Rv3367|M.tuberculosis_H37Rv         --NGLTGNDGVNPAPVTNP-------------------------------
MMAR_1161|M.marinum_M               --SGLAGSNGVNPAAVTDP-------------------------------
MUL_3507|M.ulcerans_Agy99           NFSRLGALEGAGGNGGHGG-------------------------------
MAB_4284c|M.abscessus_ATCC_199      -LAGNAGLAGNAGLAGNAG-------------------------------
MLBr_01183|M.leprae_Br4923          -AAAAQLTTEIAPPAAD---------------------------------
MAV_1346|M.avium_104                -AAAAAPTTSIAPAAAD---------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1       --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155      GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu      --------------------------------------------NGGNVG
Mb3402|M.bovis_AF2122/97            --ALNGAAG------------------------------------DSNIE
Rv3367|M.tuberculosis_H37Rv         --ALNGAAG------------------------------------DSNIE
MMAR_1161|M.marinum_M               --ALNGAAG------------------------------------DSNIN
MUL_3507|M.ulcerans_Agy99           --LLFGNGG------------------------------------GGGDA
MAB_4284c|M.abscessus_ATCC_199      ---LAGNAG-----------------------------------LAGNAG
MLBr_01183|M.leprae_Br4923          -----------------------------------------------DVS
MAV_1346|M.avium_104                -----------------------------------------------EVS
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1       AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155      HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu      FFSLFNLGG--------------------AGGWGGSGVDG----------
Mb3402|M.bovis_AF2122/97            PQTSVLIGTQGGD-----------------GTPGGAGVNG----------
Rv3367|M.tuberculosis_H37Rv         PQTSVLIGTQGGD-----------------GTPGGAGVNG----------
MMAR_1161|M.marinum_M               -GNTTWHGTNGDP-----------------GTPGGTGVNG----------
MUL_3507|M.ulcerans_Agy99           GANNKFVTAQATPN----------------GAAGGYGGNAG---------
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGNAGLAG-------------NAGLAGNAGLAGNAG-------
MLBr_01183|M.leprae_Br4923          ILLAHFFSGHGRQY------------------------------------
MAV_1346|M.avium_104                ALQAAQFSAYGTWY------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1       Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155      IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu      -----------VDVVGGNP-------------------------------
Mb3402|M.bovis_AF2122/97            ----------GNGGAGGDANGNPANTSIA---------------------
Rv3367|M.tuberculosis_H37Rv         ----------GNGGAGGDANGNPANTSIA---------------------
MMAR_1161|M.marinum_M               ----------GNGGAGGDANDDVANSSGG---------------------
MUL_3507|M.ulcerans_Agy99           --------LWGNGGAGGDGGFGGTATVIG---------------------
MAB_4284c|M.abscessus_ATCC_199      --------LAGNAGLAGNAGLAGNAGLAG---------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1       ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155      TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu      -----------DGGTPG------------------------------AHG
Mb3402|M.bovis_AF2122/97            -----------NAGAGGNGA---------------------------AGG
Rv3367|M.tuberculosis_H37Rv         -----------NAGAGGNGA---------------------------AGG
MMAR_1161|M.marinum_M               -----------LAGSGGSGA---------------------------TGG
MUL_3507|M.ulcerans_Agy99           -----------DGGTGGNGG---------------------------LLS
MAB_4284c|M.abscessus_ATCC_199      -----------NAGLAGNAG------------------------LAGNAG
MLBr_01183|M.leprae_Br4923          -------------------------------------------------Q
MAV_1346|M.avium_104                -------------------------------------------------Q
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1       GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155      AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu      ESHTPGVYTDRQ--------------------------------------
Mb3402|M.bovis_AF2122/97            DGGANGGAGGAG--------------------------------------
Rv3367|M.tuberculosis_H37Rv         DGGANGGAGGAG--------------------------------------
MMAR_1161|M.marinum_M               DGGANGGTGGAG--------------------------------------
MUL_3507|M.ulcerans_Agy99           GDGGAGGVGGTG--------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGNAG--------------------------------------
MLBr_01183|M.leprae_Br4923          AHASQGATNHQD--------------------------------------
MAV_1346|M.avium_104                QVSAQAKAIHQT--------------------------------------
                                         .                                            

Mflv_5091|M.gilvum_PYR-GCK          -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155      GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
TH_3810|M.thermoresistible__bu      -----------------GEDGEDGTGTGIGGRGGNGG-------------
Mb3402|M.bovis_AF2122/97            ----------------GQAASAGSSVGGDGGNGGAGG-------------
Rv3367|M.tuberculosis_H37Rv         ----------------GQAASAGSSVGGDGGNGGAGG-------------
MMAR_1161|M.marinum_M               ----------------GQAASYGYSSGGNGGTGGAGG-------------
MUL_3507|M.ulcerans_Agy99           ----------------GIQIYSGGGIGGVGGIGGNGG-------------
MAB_4284c|M.abscessus_ATCC_199      ---------------LAGNAGLAGNAGLAGNAAVAGN-------------
MLBr_01183|M.leprae_Br4923          -----------------LIQSLLTSSSAYAGTETAN--------------
MAV_1346|M.avium_104                -----------------LVQNLDTNADSYGATEAANR-------------
                                                                 .     .              

Mflv_5091|M.gilvum_PYR-GCK          ----TGGTGGIGGAGSTGGT--------------------------GGTG
Mvan_1264|M.vanbaalenii_PYR-1       ----TGGTGGIGGAGSTGGT--------------------------GGTG
MSMEG_0868|M.smegmatis_MC2_155      GQTDTGGNGGRGGDGGTFVN--------------------------AGAN
TH_3810|M.thermoresistible__bu      ---SSSGTHPMAEDG----------------------------------E
Mb3402|M.bovis_AF2122/97            ----TGTNGHAGGAGGAGGQAASAGSSVGGDGGNGGAGGTGTNGHAGGAG
Rv3367|M.tuberculosis_H37Rv         ----TGTNGHAGGAG-----------------------------------
MMAR_1161|M.marinum_M               ----TGADGGAGGDG-----------------------------------
MUL_3507|M.ulcerans_Agy99           ----AGGTSGLIGDG-----------------------------------
MAB_4284c|M.abscessus_ATCC_199      --AAVAGNAAVAGNAAVGGVLN---------------------------T
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKG
TH_3810|M.thermoresistible__bu      HVKALDGRPGLD---GGNGSHGGNGGHGGRGGFLGIGGSG-------GWG
Mb3402|M.bovis_AF2122/97            GAGGAGGRGGWLVGSGGNGGNGGNGAAGGNGAIGGTGGAG--GVP-ANQG
Rv3367|M.tuberculosis_H37Rv         GAGGAGGRGGWLVG---NGGNGGNGAAGGNGAIGGTGGAG--GVP-ANQG
MMAR_1161|M.marinum_M               GHGGAGGRGGWLLGDGGNGGAGGDGATGGSGATGGNGGAG--GITTADQN
MUL_3507|M.ulcerans_Agy99           GAGGAGGTGGGNAG---VGGVGGVGGTGGAARLFGSGGSG--GIG--GTG
MAB_4284c|M.abscessus_ATCC_199      GVSGAIG-GSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG
MLBr_01183|M.leprae_Br4923          -----------------------------HDSL-----------------
MAV_1346|M.avium_104                VNTSAAALQGLAPNVIPNAAPAADPPPAGTTSLGTSIGWA--------QN
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTG---------GTGGTGGTGGAG-----------DGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGTG---------GTGGTGGTGGAG-----------DGLGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGN
TH_3810|M.thermoresistible__bu      GHGGNGGD-----------TDADGGNGGDG---------------GNGGS
Mb3402|M.bovis_AF2122/97            GNSALGTQP----------VSGDGGDGGNG------------GTGGTGGR
Rv3367|M.tuberculosis_H37Rv         GNSALGTQP----------VGGDGGDGGNG------------GTGGTGGR
MMAR_1161|M.marinum_M               GYSAVGTQA----------VGGDGGNGGNG------------GSGGSGGT
MUL_3507|M.ulcerans_Agy99           GHSLINSGGG---------IGGKGGGGGAA------------GLIGDGGA
MAB_4284c|M.abscessus_ATCC_199      VGSHVGGGIS----------ESLGGSGSVG---------------GSTAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                VGAAASDFIT----------LGEGQFAPVP---------------GAAGI
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GG----TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGG
Mvan_1264|M.vanbaalenii_PYR-1       GG----TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVG
MSMEG_0868|M.smegmatis_MC2_155      GGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATN
TH_3810|M.thermoresistible__bu      AG---------------------------------RGGTGGLRGVFGING
Mb3402|M.bovis_AF2122/97            GG-------------DGG-----------------SGGAGGASGWLMGNG
Rv3367|M.tuberculosis_H37Rv         GG-------------DGG-----------------SGGAGGASGWLMGNG
MMAR_1161|M.marinum_M               GG-------------AAG-----------------SGGAGGDGGWLVGNG
MUL_3507|M.ulcerans_Agy99           GG-------------AGG-----------------NGGDGTGAGGLGGNG
MAB_4284c|M.abscessus_ATCC_199      GG----------------------------------GAHTGVGGGVSTGV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                PNFN-------------------------------PGLTAATTAGPPAPA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GTG-----------------------GQGGTGGTGGQGGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GTG-----------------------GTGGTGGTGGQGGTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANG
TH_3810|M.thermoresistible__bu      GNG------------------------RAGLGGRGXXXXGGGVGAAVRSG
Mb3402|M.bovis_AF2122/97            GNG-----------------------GNGGTGGSGGVGGNGGIGGDGAGG
Rv3367|M.tuberculosis_H37Rv         GNG-----------------------GNGGTGGSGGVGGNGGIGGDGAGG
MMAR_1161|M.marinum_M               GTG-----------------------GTGGIGGQGGIGGQGGVGGNGAVG
MUL_3507|M.ulcerans_Agy99           ASA-----------------------DWIGNGGSGGAGGSGGLGAHAGAG
MAB_4284c|M.abscessus_ATCC_199      GVG-----------------------SHVGGGISESLGGSGSVGGSTAVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                APA-----------------------AAAGAPVLASMGRGPSIGGLSVPP
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGA
Mvan_1264|M.vanbaalenii_PYR-1       --------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGA
MSMEG_0868|M.smegmatis_MC2_155      PSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGG
TH_3810|M.thermoresistible__bu      ---------------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSR
Mb3402|M.bovis_AF2122/97            --------GNATSTSSIPFDAHGGNGGAGGDAGHGGTGGDGGDGGHAGTG
Rv3367|M.tuberculosis_H37Rv         --------GNATSTSSIPFDAHGGNGGAGGDAGHGGTGGDGGDGGHAGTG
MMAR_1161|M.marinum_M               --------GNAHSP---ILDAHGGDGGAGGDAGHGGTGGDGGDGGLSGAG
MUL_3507|M.ulcerans_Agy99           --------GNGGSLY-----GNDGSGGAGG-TGASGAGGNGGGGGAAGMM
MAB_4284c|M.abscessus_ATCC_199      --------GGAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVGGSTAVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ------------------SWAPGGVAPAANATPAQLVGAGFTSAAPDTAP
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQG
Mvan_1264|M.vanbaalenii_PYR-1       GG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQG
MSMEG_0868|M.smegmatis_MC2_155      DGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVA
TH_3810|M.thermoresistible__bu      EG------------------------IMPSSRAASARAG-----------
Mb3402|M.bovis_AF2122/97            GR----------------------GGLLAGQHANSGNGG-----------
Rv3367|M.tuberculosis_H37Rv         GR----------------------GGLLAGQHANSGNGG-----------
MMAR_1161|M.marinum_M               GR----------------------GGLLAGLQGSTGSGG-----------
MUL_3507|M.ulcerans_Agy99           GD----------------------GGAGGDGGDGSAAGG-----------
MAB_4284c|M.abscessus_ATCC_199      GG-------------------AHTSAINDALGGSGSVGG-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                VT------------------------AVPGGVPSMATAG-----------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG----------
Mvan_1264|M.vanbaalenii_PYR-1       ATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG----------
MSMEG_0868|M.smegmatis_MC2_155      GNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHG
TH_3810|M.thermoresistible__bu      ----------------AACASSTSRSRRSFCCSRA---------------
Mb3402|M.bovis_AF2122/97            ----------------GGGTGGAGGTHGTPGSGNAGGTG-----------
Rv3367|M.tuberculosis_H37Rv         ----------------GGGTGGAGGTHGTPGSGNAGGTG-----------
MMAR_1161|M.marinum_M               ----------------AGGTGGDGGSPGTVGSGKAGGTG-----------
MUL_3507|M.ulcerans_Agy99           ----------------LGGDGGNADWLGN-GGGGTGGFG-----------
MAB_4284c|M.abscessus_ATCC_199      ------------STAVGGGAHTSAINESMNSSINASHSSSMN--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                ----------------RGGYGLGAPRYGVKPTVMPKPAI-----------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGE
Mvan_1264|M.vanbaalenii_PYR-1       -TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGD
MSMEG_0868|M.smegmatis_MC2_155      AITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            ---TGNADSTNGGPGSDGLGGDAFNGSRGTDGNPG---------------
Rv3367|M.tuberculosis_H37Rv         ---TGNADSTNGGPGSDGLGGDAFNGSRGTDGNPG---------------
MMAR_1161|M.marinum_M               ---TGDGNSTNGGPGANGLGGAAFDGARGADGNPG---------------
MUL_3507|M.ulcerans_Agy99           ---LPPATGGFGGRGGRLFGSPGAQGRRALMCLSAACRC-----------
MAB_4284c|M.abscessus_ATCC_199      -ESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH--------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          DGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGA
Mvan_1264|M.vanbaalenii_PYR-1       AGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGS
MSMEG_0868|M.smegmatis_MC2_155      GGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1161|M.marinum_M               --------------------------------------------------
MUL_3507|M.ulcerans_Agy99           --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          E--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAA
Mvan_1264|M.vanbaalenii_PYR-1       E--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAA
MSMEG_0868|M.smegmatis_MC2_155      EPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb3402|M.bovis_AF2122/97            --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_1161|M.marinum_M               --------------------------------------------------
MUL_3507|M.ulcerans_Agy99           --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_1346|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GDSDD
Mvan_1264|M.vanbaalenii_PYR-1       GDSD-
MSMEG_0868|M.smegmatis_MC2_155      GANNP
TH_3810|M.thermoresistible__bu      -----
Mb3402|M.bovis_AF2122/97            -----
Rv3367|M.tuberculosis_H37Rv         -----
MMAR_1161|M.marinum_M               -----
MUL_3507|M.ulcerans_Agy99           -----
MAB_4284c|M.abscessus_ATCC_199      -----
MLBr_01183|M.leprae_Br4923          -----
MAV_1346|M.avium_104                -----