For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. vanbaalenii PYR-1 Mvan_5188 (-)

annotation: hypothetical protein Mvan_5188
coordinates: 5553490 - 5555250
length: 586

MFDSGLAGLDEPALLAAIERAACEESRAGARKSAAIAALVHESVTFDDVRDQWVWDSWIETACELGAVLN
TSHRRASALMRIAVALRDRLPKVAALFAAGRLSTRLIGQVTWRTRLVQDPQLLALLDTAIADKATRWEPL
SDDKLTAALDAVIERYDPDAVIRAREHVSGLDFRVGASDDPDALVTVWGKILGCDAAVLAARIAELLKGL
CDNDPRSVCVRRSHAVGAIVRGQDHLRCRCGSPDCTAAAVVPGSSNVVISVLADPAALDAVRQLIADQDR
DQQDKLADKQAKAKEQGKAESQPQTEPIPQPEAEAEAEPEPEAEVEVEPEAETETAIESEPAPVKPVAPS
NPAACVRDSGVALLPGVKILPLVALAEAIRSGAATKTLWLPGPDPEPHYRPSAKLAAFVRARDLFCRYPG
CDVPAEHCDLDHVVPYPYGPTHPSNLNCKRRTHHLGKTFAEGWQEQQLPDGTVLWTTPAGQRCTTVPGSW
LFFPGWDTTTAELPPMAQPPPDPDRLAKMPKRRRTRAADQAARIKVEREHNATQRALETERAKTPEQARR
AEQVRYAGLPPPASPQPDYGNDPPPF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5188--100% (586)hypothetical protein Mvan_5188
M. vanbaalenii PYR-1Mvan_2714-0.083.03% (607) hypothetical protein Mvan_2714
M. vanbaalenii PYR-1Mvan_2144-0.082.51% (606) hypothetical protein Mvan_2144

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2126-1e-11343.90% (549) hypothetical protein Mb2126
M. gilvum PYR-GCKMflv_1272-0.076.74% (589) HNH endonuclease
M. tuberculosis H37RvRv2100-1e-11343.90% (549) hypothetical protein Rv2100
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4752-3e-3738.26% (264) hypothetical protein MAB_4752
M. marinum MMMAR_5187-4e-6934.21% (573) 13e12 repeat-containing protein
M. avium 104MAV_4456-1e-5733.33% (582) 13e12 repeat-containing protein
M. smegmatis MC2 155MSMEG_5583-1e-10537.46% (622) HNH endonuclease
M. thermoresistible (build 8)TH_0334-2e-3634.44% (270) HNH endonuclease
M. ulcerans Agy99MUL_2679-7e-3936.92% (260) 13e12 repeat-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_5187|M.marinum_M               --------------------MFESMGVAAGVDHPCDALAERRQLRTPT--
MAV_4456|M.avium_104                --------------------------MCEDATAWFDELMER-CYPSAT--
MUL_2679|M.ulcerans_Agy99           ----------------------------------MDQHIIEYVFDT----
TH_0334|M.thermoresistible__bu      ------------------------------------------MFES----
MAB_4752|M.abscessus_ATCC_1997      ------------------------------------------MFDE----
Mvan_5188|M.vanbaalenii_PYR-1       --------------------------------------MFDSGLAG----
Mflv_1272|M.gilvum_PYR-GCK          --------------------------------------MFDSGLAG----
Mb2126|M.bovis_AF2122/97            MAGALFEPSFAAAHPAGLLRRPVTRTVVLSVAATSIAHMFEISLPDPTEL
Rv2100|M.tuberculosis_H37Rv         MAGALFEPSFAAAHPAGLLRRPVTRTVVLSVAATSIAHMFEISLPDPTEL
MSMEG_5583|M.smegmatis_MC2_155      ---------------MCLLVVPVCDTGCMP---------FEHTFDD----
                                                                                      

MMAR_5187|M.marinum_M               --AESARWVQRIGAAARAENRAAAAQLIEIGQLFAYRLSR--CSETEDWA
MAV_4456|M.avium_104                --PESAALVQRIGVFARVENRAAAEQLAAIGELFAYRLSR--CSECEDWA
MUL_2679|M.ulcerans_Agy99           ---DDSAPLTRITAAARAEARAAAERLAAIGDLFRLRLSQ--HGNREDWV
TH_0334|M.thermoresistible__bu      --LDDGAVVDSIAAASREQSAACGREMLAIGELYARRAPED-DTERANWA
MAB_4752|M.abscessus_ATCC_1997      --LGDVELIDLIASAQRAEAQACARKLDAIGVLVDRHADLGKPDERDHHA
Mvan_5188|M.vanbaalenii_PYR-1       --LDEPALLAAIERAACEESRAGARKSAAIAALVHESVT--FDDVRDQWV
Mflv_1272|M.gilvum_PYR-GCK          --LDKPALISAIEQAACEEVRAGARKTAAIAALVHDHVT--YDDVRDEWV
Mb2126|M.bovis_AF2122/97            CRSDDGALVAAIEDCARVEAAASARRLSAIAELTGRRTG---ADQRADWA
Rv2100|M.tuberculosis_H37Rv         CRSDDGALVAAIEDCARVEAAASARRLSAIAELTGRRTG---ADQRADWA
MSMEG_5583|M.smegmatis_MC2_155      --LDDAALVAGIEGCERAQNAAAARKLALVARFTARRAAD-SEDEVLRWA
                                        .   :  *      :  * . .   :. :                .

MMAR_5187|M.marinum_M               VDTMEAVAAEVAAGLRISQGLAASRLRYARALRERLPKTGAVFAAGQIDL
MAV_4456|M.avium_104                VDTEAAVSAEVAAQLRIGQGLAAAKVRYARAMRERLPRVGEVFRAGEIDF
MUL_2679|M.ulcerans_Agy99           ADTCDAVAAEVAAALNTSVAMGHSNLRYARAMRERLPQLGAEFRAGGIDF
TH_0334|M.thermoresistible__bu      IDGHANVVAEISAALNISRGRAAGRLQLAIDLRERLPRVAAVFAAGDIDF
MAB_4752|M.abscessus_ATCC_1997      LDRWDRVASEVAAAQGITHALASSQMRYAQVLRHRLRAVAERFAAGDLDF
Mvan_5188|M.vanbaalenii_PYR-1       WDSWIETACELGAVLNTSHRRASALMRIAVALRDRLPKVAALFAAGRLST
Mflv_1272|M.gilvum_PYR-GCK          WDSWIETACELGAVLNTSHRRASAQMRIAVALRDRLPGVAALHAQGRLSA
Mb2126|M.bovis_AF2122/97            CDFWDCAAAEVAAALTISHGKASGQMHLSLAL-NRLPQVAALFLAGHLGA
Rv2100|M.tuberculosis_H37Rv         CDFWDCAAAEVAAALTISHGKASGQMHLSLAL-NRLPQVAALFLAGHLGA
MSMEG_5583|M.smegmatis_MC2_155      GDDWAATAAEVGAALNVGPAVASKWMRVAQEVGERLPRVQEMFAAGWLSA
                                     *    . .*:.*        .   :: :  : .**      .  * :. 

MMAR_5187|M.marinum_M               RAFQTIVFRTDLIVDPQVMAAVDALVALNVGRWPSMTKARLSGQIDAIVA
MAV_4456|M.avium_104                RLFATIVYRTDLITDRRVLAAVDAELAATAARWPSMTRARLAARVDAVVA
MUL_2679|M.ulcerans_Agy99           RLFRTIVFRTDLITESDALAAVDARLAIKAPRWPSMTSWKLATEVDRVVA
TH_0334|M.thermoresistible__bu      RMVSALVNRSRNVVDPDLLARLDAALAAWSPKWMKLSGPTLNERIDMWVE
MAB_4752|M.abscessus_ATCC_1997      RTVALIINRTELVDDEAVVARVDAAIVRALPRWARWSHKRITAALDALVL
Mvan_5188|M.vanbaalenii_PYR-1       RLIGQVTWRTRLVQDPQLLALLDTAIADKATRWEPLSDDKLTAALDAVIE
Mflv_1272|M.gilvum_PYR-GCK          RLIGQITWRTRLVQDPQALALIDAAIAEKATRWEPLSEDNLTAALDAVIE
Mb2126|M.bovis_AF2122/97            RLFSIIAWRTYLVRDPHALSLLDAALAEHAGAWGPLSAPKLEKAIDSWID
Rv2100|M.tuberculosis_H37Rv         RLFSIIAWRTYLVRDPHALSLLDAALAEHAGAWGPLSAPKLEKAIDSWID
MSMEG_5583|M.smegmatis_MC2_155      QVVATLTWATHLVGDEQVLAIVDAQLAARAREFGPMTVDGVKAAVASLLE
                                    : .  :   :  : :   :: :*: :.     :   :   :   :   : 

MMAR_5187|M.marinum_M               RADADAVRRRKERHADREIWIGQDADG--ISRIDGSMFTIDAHALDRRLS
MAV_4456|M.avium_104                KADADAVRRTEKQAASRHVWIAEMGEG--LSHLEGTVSSPDAHALDKRLD
MUL_2679|M.ulcerans_Agy99           KFDRDAVRRSRRDAADRYVDCAPLEPG--MALVNRQVFSATAEALARRLD
TH_0334|M.thermoresistible__bu      RFDPTGVREPRSPGEDRYVVVTPAGQG--MVDVSARLTFEAGFAFXTRLD
MAB_4752|M.abscessus_ATCC_1997      HFDQDAVRRNRSATDKRHLEIRPLGNGEPVAEVWGTLQAVHAVALDKRLD
Mvan_5188|M.vanbaalenii_PYR-1       RYDPDAVIRAREHVSGLDFRVGASDDPDALVTVWGKILGCDAAVLAARIA
Mflv_1272|M.gilvum_PYR-GCK          RFDPDAVIRTREQLKGVDFRIGASDDPDALVTVWGKILGCDAVVLAARIA
Mb2126|M.bovis_AF2122/97            RYDPGALRRSRISARTRDLCIGDPDEDAGTAALWGRLYATDAAMLDRRLT
Rv2100|M.tuberculosis_H37Rv         RYDPGALRRSRISARTRDLCIGDPDEDAGTAALWGRLYATDAAMLDRRLT
MSMEG_5583|M.smegmatis_MC2_155      KYDPAAVRRSREASRDRDVRFGKPDDVTGTVSISGRVNTADAVAYQKRSA
                                    : *  .: . .       .             :   :    .     *  

MMAR_5187|M.marinum_M               ALAATVCAQDPRSREQRRADALGVLAAGGDRLGCRCGLPDC--AAGARPA
MAV_4456|M.avium_104                ALAATVCEHDPRTGEQRRADALGALAAGADRLGCRCGRADC--AAGTRPA
MUL_2679|M.ulcerans_Agy99           ELAKTVCADDPRTVVQRRADALGTLAAGQDRLICDCGRTDCP-AAGAPQQ
TH_0334|M.thermoresistible__bu      QIAATVCRDDPRTADQRRADAMAAMSEGQNRLVCGCGSEDCP-ADPADTA
MAB_4752|M.abscessus_ATCC_1997      LLAGTVCPADPRSKTQRRADAVGALTQGLNRMRCACGHPDC---SGRDTA
Mvan_5188|M.vanbaalenii_PYR-1       ELLKGLCDNDPRSVCVRRSHAVGAIVRGQDHLRCRCGSPDCT-AAAVVPG
Mflv_1272|M.gilvum_PYR-GCK          ELLKGLCDADPRGIGERRSCAVGAIVRGQDHLPCRCGSPDCA-AAPVVPG
Mb2126|M.bovis_AF2122/97            EMAHGVCEDDPRTLAQRRADALGALAAGADHLACGCGKPDCPSGAGNDER
Rv2100|M.tuberculosis_H37Rv         EMAHGVCEDDPRTLAQRRADALGALAAGADHLACGCGKPDCPSGAGNDER
MSMEG_5583|M.smegmatis_MC2_155      HLTGGVCGDDPRTAGQRRADAFGVIAVQGDRLVCLCGDPQCP-WAGVDPR
                                     :   :*  ***    **: *...:    ::: * **  :*         

MMAR_5187|M.marinum_M               AQPVVIHVIAERATLDGDGG------------------------------
MAV_4456|M.avium_104                AGPVVIHLIAERASVEGTGG------------------------------
MUL_2679|M.ulcerans_Agy99           PSRVVIHVVAGCQTVDGAGE------------------------------
TH_0334|M.thermoresistible__bu      ATRLVINVIAEQATVEGRSD------------------------------
MAB_4752|M.abscessus_ATCC_1997      DVPVVVNVVINQSTLAGSDD------------------------------
Mvan_5188|M.vanbaalenii_PYR-1       SSNVVISVLADPAALDAVRQLIADQD--------------------RDQQ
Mflv_1272|M.gilvum_PYR-GCK          SSNVVISVLADPAALEAVRSLIADED--------------------RHQQ
Mb2126|M.bovis_AF2122/97            AAGVVIHVVADASALDAQPDPHLSGD------------------------
Rv2100|M.tuberculosis_H37Rv         AAGVVIHVVADASALDAQPDPHLSGD------------------------
MSMEG_5583|M.smegmatis_MC2_155      AANTMVHIFAEPSVVDAKPDPYVHGDYASNPVPFVDPEFDPWPVYPERDS
                                        :: :.     : .                                 

MMAR_5187|M.marinum_M               --------------------------------------------------
MAV_4456|M.avium_104                --------------------------------------------------
MUL_2679|M.ulcerans_Agy99           --------------------------------------------------
TH_0334|M.thermoresistible__bu      --------------------------------------------------
MAB_4752|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_5188|M.vanbaalenii_PYR-1       DKLADKQAKAKEQGKAESQPQTEPIPQPEAEAEAEPEPEAEVEVEPEAET
Mflv_1272|M.gilvum_PYR-GCK          DALAEKQPHA-------------------VKAKEQGEPAAP---------
Mb2126|M.bovis_AF2122/97            ----EPPSRP-----------LTPETTLFEALTPDPEPDP----------
Rv2100|M.tuberculosis_H37Rv         ----EPPSRP-----------LTPETTLFEALTPDPEPDP----------
MSMEG_5583|M.smegmatis_MC2_155      TPPPEPPSEPQWAPQWWSEIPLPPEPEPEPEPEPEPEPEPEPEPELRFES
                                                                                      

MMAR_5187|M.marinum_M               --------------------------------------------------
MAV_4456|M.avium_104                --------------------------------------------------
MUL_2679|M.ulcerans_Agy99           --------------------------------------------------
TH_0334|M.thermoresistible__bu      --------------------------------------------------
MAB_4752|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_5188|M.vanbaalenii_PYR-1       ETAIESEPAPVKP-------------------------------------
Mflv_1272|M.gilvum_PYR-GCK          --------------------------------------------------
Mb2126|M.bovis_AF2122/97            --------------------------------------------------
Rv2100|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_5583|M.smegmatis_MC2_155      EPQTASAPQPEPEPEARPEPQPKTGPEPEPVSTPKPQPQDPPAAAESWGG
                                                                                      

MMAR_5187|M.marinum_M               --------APA----------WEVGADGLVTPELVAELAKSAKLVPLRHP
MAV_4456|M.avium_104                --------GPA----------VEVGAEGLLPAQLVAELAASARLMPLVHP
MUL_2679|M.ulcerans_Agy99           --------APG----------VLPG-DGIIPAEIVRELAKSAKLQPMSTP
TH_0334|M.thermoresistible__bu      --------NPG----------YLPG-YGAVPASILRAKAATATLRPVALP
MAB_4752|M.abscessus_ATCC_1997      --------CPA----------HVPG-FGVLAAESARAAVAGTPTRNLTDS
Mvan_5188|M.vanbaalenii_PYR-1       ----VAPSNPAACVR-DSGVALLPGVKILPLVALAEAIRSGAATKTLWLP
Mflv_1272|M.gilvum_PYR-GCK          -----APSNRGRCVR-DSGTALLPGVKILPIVALAEAIRAGAAIKQLWLP
Mb2126|M.bovis_AF2122/97            ----PATHAPAELIT--------TGGGVVPAPLLAELIRGGATISQVRHP
Rv2100|M.tuberculosis_H37Rv         ----PATHAPAELIT--------TGGGVVPAPLLAELIRGGATISQVRHP
MSMEG_5583|M.smegmatis_MC2_155      GGVNPLVVAPAPVVSPQRATAVIVGGGLVPASYVAQMIASGAKVKQGRVP
                                              .             *                :       .

MMAR_5187|M.marinum_M               GDVPPEPGYVPSKALADFVRCRDLTCRWPGCDHPALNCDLDHTIPYAQGG
MAV_4456|M.avium_104                ADAPPENRYTPSAALADFVRCRDLTCRWPGCDRPATECDLDHTIPYAEGG
MUL_2679|M.ulcerans_Agy99           --ILAETGYVPSPALMDFVRARDLTCRAPGCDRPATQCDVDHTIPYSDGG
TH_0334|M.thermoresistible__bu      -QPCAEAGYRPSAALTRFIRCRDLTCRFPGCDAPAAVCQIDHTIPYPAG-
MAB_4752|M.abscessus_ATCC_1997      ----RSTGYRPSAKLAAFVRSRDQLCRFPGCEAVADRADIDHTVPWATGG
Mvan_5188|M.vanbaalenii_PYR-1       GP-DPEPHYRPSAKLAAFVRARDLFCRYPGCDVPAEHCDLDHVVPYPYG-
Mflv_1272|M.gilvum_PYR-GCK          GP-DPEPHYRPSAKLAAFVRARDLFCRYPGCNVPAEQCDIDHVVPWPYG-
Mb2126|M.bovis_AF2122/97            GDLAAEPHYRPSAKLAEFVRMRDLTCRFPGCDVPAEFCDIDHSAPWPLG-
Rv2100|M.tuberculosis_H37Rv         GDLAAEPHYRPSAKLAEFVRMRDLTCRFPGCDVPAEFCDIDHSAPWPLG-
MSMEG_5583|M.smegmatis_MC2_155      LE-DPESGYRPSVGLAEFVRMRDLTCRFPGCGRPAECCDIDHTEPFPGG-
                                         .  * **  *  *:* **  ** ***   *  .::**  *:. * 

MMAR_5187|M.marinum_M               PTHASNLKCYCRTHHLVKTFWG-WHDQQLPDGTLILTSPAGHTYVTTPGS
MAV_4456|M.avium_104                PTHASNLKCYCRTHHLVKTFWG-WREQQLPDATLILTSPAGRTYVTTPGS
MUL_2679|M.ulcerans_Agy99           ATHPSNLKCLCRKHHLLKTFWG-WHDEQLPDATVIWSLPDGQTYVTTPGS
TH_0334|M.thermoresistible__bu      PTHPSNLKLLCVFHCRQAELRF-THDQHKHQSSCLP------AYFQRPHG
MAB_4752|M.abscessus_ATCC_1997      PTTGANLKALCRKHHLLKTFGQ-WTELQEPDGTVIWKSPTGHRYATTPVS
Mvan_5188|M.vanbaalenii_PYR-1       PTHPSNLNCKRRTHHLGKTFAEGWQEQQLPDGTVLWTTPAGQRCTTVPGS
Mflv_1272|M.gilvum_PYR-GCK          PTHPSNLNCKCRTHHLGKTFAEGWHEEQLPDGTVIWTTPAGQRYSTVPGS
Mb2126|M.bovis_AF2122/97            PTHPSNLKCACRKHHLLKTFWTGWRDVQLPDGTVIWTAPNGHTYTTHPGS
Rv2100|M.tuberculosis_H37Rv         PTHPSNLKCACRKHHLLKTFWTGWRDVQLPDGTVIWTAPNGHTYTTHPGS
MSMEG_5583|M.smegmatis_MC2_155      VTHASNIKCLCRFHHLIKTFWAGFVDTQLPDGQVVWTMPSGRTYTTVPGS
                                     *  :*::     *     :     : :  :.  :            * .

MMAR_5187|M.marinum_M               ALLFPSLCHSTGGLPAAEADPPSDHCDQRSAMMPRRQRTRAQDRARRVAT
MAV_4456|M.avium_104                ALLFPSLCVPTG-EPARPVAAGSQPCGERTAMMPTRRRTRGQNRAARVAA
MUL_2679|M.ulcerans_Agy99           AWLLPGLFAPSPELPPP----------------PRSEATGSLRKPRRDDA
TH_0334|M.thermoresistible__bu      ---------------------------------PATRRPPSARGLREAVP
MAB_4752|M.abscessus_ATCC_1997      WFLFP---------------------------ALTRHHTRQQARDRRRRT
Mvan_5188|M.vanbaalenii_PYR-1       WLFFPGWDTTTAELPPMAQPPPDP---DRLAKMPKRRRTRAADQAARIKV
Mflv_1272|M.gilvum_PYR-GCK          RLFFPGWDTTTAELPPMAQPPPDP---DRLAKMPKRRRTRAADHAARIKA
Mb2126|M.bovis_AF2122/97            RIFFPTWHTTTAELPQTSTAAVNVD--ARGLMMPRRRRTRAAELAHRINA
Rv2100|M.tuberculosis_H37Rv         RIFFPTWHTTTAELPQTSTAAVNVD--ARGLMMPRRRRTRAAELAHRINA
MSMEG_5583|M.smegmatis_MC2_155      RWVFPQWDTTTTTLPPPPPRATSP---ARGVMMPQRKLTRAEQRARQIRA
                                                                        . .       .   

MMAR_5187|M.marinum_M               ERRQNHHARSTQPGGQPR-----------------------SAAPPTPPQ
MAV_4456|M.avium_104                ERRANRAARLARATRPAP-----------------------AASQSWPAG
MUL_2679|M.ulcerans_Agy99           QTRPNSRPKLGR-----------------------------THCDRTQPQ
TH_0334|M.thermoresistible__bu      RQGVDPRRVSGQ--------------------------------------
MAB_4752|M.abscessus_ATCC_1997      ERNLNREQRLQREAALAA-----------------------LAAKDPPPF
Mvan_5188|M.vanbaalenii_PYR-1       EREHNATQRALETERAKTPEQARRAEQVRYAGLPPPASPQPDYGNDPPPF
Mflv_1272|M.gilvum_PYR-GCK          EREDNAHQRALETERAAA----------RRSGLPPPAP--PDYGDDPPPF
Mb2126|M.bovis_AF2122/97            ER---ALNDAYMAE-----------------------------RNKPPSF
Rv2100|M.tuberculosis_H37Rv         ER---ALNDAYMAE-----------------------------RNKPPSF
MSMEG_5583|M.smegmatis_MC2_155      ER---ARNEKYLSE-----------------------------RNKPPPQ
                                    .                                                 

MMAR_5187|M.marinum_M               SEPQSHPPPF
MAV_4456|M.avium_104                HGPDADPPPF
MUL_2679|M.ulcerans_Agy99           HD--------
TH_0334|M.thermoresistible__bu      ----------
MAB_4752|M.abscessus_ATCC_1997      ----------
Mvan_5188|M.vanbaalenii_PYR-1       ----------
Mflv_1272|M.gilvum_PYR-GCK          ----------
Mb2126|M.bovis_AF2122/97            ----------
Rv2100|M.tuberculosis_H37Rv         ----------
MSMEG_5583|M.smegmatis_MC2_155      ----------