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RERKKRRTRATLIDAAVGLCDRQGYDATTVDQIAHVAEVSPRTFSRYFATKDAIALALIDEVLVHTAVEL VRQPRYLPHMEALRRAYVAMAEASKLAPPGALSAQRLLQILRIIVSSPTLRQAAVGYRAGPVDAVVAERM GATVDDRRVKLVAAVWGVVLMTALQDVCRSAVDFGVDDVIAAVEATYAEFAGEIAGVVQPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5023 | - | - | 100% (202) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1157 | - | 3e-14 | 34.94% (166) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0384 | - | 6e-14 | 34.94% (166) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 1e-05 | 25.13% (191) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1728 | - | 3e-75 | 71.92% (203) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0691c | - | 1e-05 | 25.13% (191) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 2e-07 | 32.37% (173) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3438 | - | 8e-12 | 30.24% (205) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4894 | - | 1e-17 | 38.92% (167) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 4e-47 | 49.50% (200) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4253 | - | 4e-36 | 44.04% (193) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2714 | - | 5e-12 | 30.24% (205) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3438|M.marinum_M --MPDDHPPTGLRQRKKADTRRALSDAALALAFERG-LDNVTREDIANVA
MUL_2714|M.ulcerans_Agy99 --MPDDHPPTGLRQRKKADTRRALSDAALALAFERG-LDNVTREDIANVA
Mb0710c|M.bovis_AF2122/97 --MPHESRVG----RRRSTTPHHISDVAIELFAAHG-FTDVSVDDIARAA
Rv0691c|M.tuberculosis_H37Rv --MPHESRVG----RRRSTTPHHISDVAIELFAAHG-FTDVSVDDIARAA
Mvan_5023|M.vanbaalenii_PYR-1 -----------MRERKKRRTRATLIDAAVGLCDRQG-YDATTVDQIAHVA
Mflv_1728|M.gilvum_PYR-GCK MAEPRGEPVLGLRERKKRRTRATLIDAAMGLCDRQG-FDATTVDQIAAIA
MSMEG_5673|M.smegmatis_MC2_155 --MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQG-YEQTTVEQIAAAA
TH_4253|M.thermoresistible__bu ----------------------MLTDAAVELFLRHG-YENTTVDQIAAVA
MAV_4894|M.avium_104 --MPASEAPPGLRERKKIKTRQAIRREAFRLIEQNG-YAATTVEQIAEAA
MAB_0248c|M.abscessus_ATCC_199 -----MRPASGLREQKKSETKLALSRAALELALDRGDLAAVTVDDIADAV
: *. * .* .: ::** .
MMAR_3438|M.marinum_M GVSLRTFNNYFTGKYEALAYRQTERMRRSIAALRERPAGEPLWTAIAHAV
MUL_2714|M.ulcerans_Agy99 GVSLRTFNNYFTGKYEALAYRQTERMRRSIAALRERPAGEPLWTAIAHAV
Mb0710c|M.bovis_AF2122/97 GIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAAL
Rv0691c|M.tuberculosis_H37Rv GIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAAL
Mvan_5023|M.vanbaalenii_PYR-1 EVSPRTFSRYFATKDAIALALIDEVLVHTAVELVRQPRYLPHMEALRRAY
Mflv_1728|M.gilvum_PYR-GCK EVSPRTFSRYFATKDAIALALIDEVLDSAAAELARQPLDIGNFEALRRAY
MSMEG_5673|M.smegmatis_MC2_155 EVSARTFSRYFATKDAVMLAFLDDVVDLVAGELAQQPPELGELDAVFCAH
TH_4253|M.thermoresistible__bu DVSPRTFSRYFATKDAVIVTLLDENLDQGARALREQPADMNHYDALFCAY
MAV_4894|M.avium_104 DVSPSTFFRYFGSKESLLLA--DDLDPLILDALKAQPRELSLPQAFRRAY
MAB_0248c|M.abscessus_ATCC_199 RVSARTFRNYFTSKEDAVLFSLRGIEDNAVALLRQRPQHEHVVDSLEAVM
:: *: .*: * * :. .
MMAR_3438|M.marinum_M LEPLQADLHEATADEDRLPSRGELAEVRKLLMNPQIREAASRELLEDWRD
MUL_2714|M.ulcerans_Agy99 LEPLQADLHEATADEDRLPSRGELAEVRKLLMNPQIREAASRELLEDWRD
Mb0710c|M.bovis_AF2122/97 LAFNTFDESETIRHRKRMR---VILQTPELQAYSMTMYAGWREVIAKF--
Rv0691c|M.tuberculosis_H37Rv LAFNTFDESETIRHRKRMR---VILQTPELQAYSMTMYAGWREVIAKF--
Mvan_5023|M.vanbaalenii_PYR-1 VAMAEASKLAPPGALSAQR---LLQILRIIVSSPTLRQAAVGYRAGPVDA
Mflv_1728|M.gilvum_PYR-GCK IAMARNTKLAAAGALTSER---MLQILRIVMSSGTLRQATVEYRASKVDR
MSMEG_5673|M.smegmatis_MC2_155 ITAFEKTRVAMPGQLTDDR---LLAAARIFTSSPSLMQATMGFRPAPLFE
TH_4253|M.thermoresistible__bu RLFYARTKDAGPDDLTSDR---VVAMTRIIMCSPTLRQAVGEFRPHAVNV
MAV_4894|M.avium_104 ATVLSQLPDDQLEFESTRQ-----RLMFSIPELKAAMYDEYYRTVTVAAE
MAB_0248c|M.abscessus_ATCC_199 LDLATSEAFSTTVAVTRLS-----AQNPGLAAHDAARSEDVG---TVVLT
.
MMAR_3438|M.marinum_M AIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYAT--ADPPVAITELIR
MUL_2714|M.ulcerans_Agy99 AIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYAT--ADPPVAITELIR
Mb0710c|M.bovis_AF2122/97 -VARRSGGK-TTDFMPQTVAWTMLGVALSAYEHWLR--DES-VSLTEALG
Rv0691c|M.tuberculosis_H37Rv -VARRSGGK-TTDFMPQTVAWTMLGVALSAYEHWLR--DES-VSLTEALG
Mvan_5023|M.vanbaalenii_PYR-1 VVAERMGAT-VDDRRVKLVAAVWGVVLMTALQDVCR-SAVD-FGVDDVIA
Mflv_1728|M.gilvum_PYR-GCK LLAERMGTS-VHDRRVKLLAAVWGAVLITAMDDLAR-KHVSGISVDDVIS
MSMEG_5673|M.smegmatis_MC2_155 VLAKRMGVS-ADDRKIALIASLWNAIMTTALVQLVPDVDWATVTVERIVN
TH_4253|M.thermoresistible__bu ALAERMAVD-LEDSRLRLVSSVWDAIMWASQQDLGPHTDWDTVTVDNLIE
MAV_4894|M.avium_104 AIAHRIGRA-ADDFEVRVFAGALTGAMMAAFDSAPT--------TPETIY
MAB_0248c|M.abscessus_ATCC_199 EVSRRAGLDPDVDLYPRLVCNAAYAVLATVIQLAVS-GSKLSKDPGALVA
::.* . * . : :
MMAR_3438|M.marinum_M AGFASVAAGLPEPAKPGEQRG
MUL_2714|M.ulcerans_Agy99 AGFASVAAGLPEPAKPGEQRG
Mb0710c|M.bovis_AF2122/97 AAFDVVGAGLDRLNQ------
Rv0691c|M.tuberculosis_H37Rv AAFDVVGAGLDRLNQ------
Mvan_5023|M.vanbaalenii_PYR-1 AVEATYAEFAGEIAGVVQPV-
Mflv_1728|M.gilvum_PYR-GCK AFDDTYAEFAGEIAGIGQPV-
MSMEG_5673|M.smegmatis_MC2_155 QMRTTYAEFLEVAGRRHEFA-
TH_4253|M.thermoresistible__bu RMEHTYRQFVAQASAIGRPV-
MAV_4894|M.avium_104 RALDFMDAGMPLD--------
MAB_0248c|M.abscessus_ATCC_199 QGFQRLRDGLA----------