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M. vanbaalenii PYR-1 Mvan_4956 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 5300364 - 5301578
length: 404

TAESEDQRDNPTDSQSQAQFRQQVRAWCRDHIPADWRDTQTGVGDEEFVRFQKAWFAELHSAGYAVPHWP
AEWGGGLPVDRQVVLYQELAAHDAPRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGEIWVQGFSEP
EAGSDLAALRTTARRAGDEFVVNGQKLWASGGMHADWCLLLARTDPDAPKRPGARKSAGISYFLMDMTTP
GVDVRPIRNAIGDSHFCEIFLDDVRIPAANLIGAENNGWQVAQATLGAERGLTMLELAERLGNAGFRWLV
QSAPVDDPIVADRLAGFETEITGLRGLCRQIVERGATGPADASVVKLYYSELLQRLTDFAVEIGGPEAHT
VLAKPMSSGWESGSWVLDFVGSWEWTIPGGASEIQRTIIAERGLGLPREPGAA*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_4956 - - 100% (404) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4006 - 3e-62 38.39% (409) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4379 - 1e-61 40.15% (401) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 3e-61 38.38% (396) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_1794 - 0.0 87.99% (383) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 3e-61 38.38% (396) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 3e-24 26.17% (321) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 5e-57 35.43% (398) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_3737 fadE17_1 5e-60 39.60% (399) acyl-CoA dehydrogenase FadE17_1
M. avium 104 MAV_2619 - 3e-69 41.10% (399) acyl-CoA dehydrogenase domain-containing protein
M. smegmatis MC2 155 MSMEG_5619 - 0.0 78.73% (395) acyl-CoA dehydrogenase domain-containing protein
M. thermoresistible (build 8) TH_3515 - 0.0 81.44% (388) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_3681 fadE17_1 4e-60 39.60% (399) acyl-CoA dehydrogenase FadE17_1

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           --------------MQDV-------------EEFRAQVRGWLADNLAGEF
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV-------------EEFRAQVRGWLADNLAGEF
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSD-----------DQVRTEIREWLAENLVGEF
Mvan_4956|M.vanbaalenii_PYR-1       -------------MTAESEDQRDNPTDSQSQAQFRQQVRAWCRDHIP---
Mflv_1794|M.gilvum_PYR-GCK          --------------MSELET-------------FRAEVRDWCREHVP---
MSMEG_5619|M.smegmatis_MC2_155      --------------MTHPEN----------LDDFRATVRDWCAAHVP---
TH_3515|M.thermoresistible__bu      --------------MTG-------------LDEFRDEVRTWCAEHIP---
MAV_2619|M.avium_104                --------------MDLDFTP--------DQLEFRDQVRTWLDENKP---
MMAR_3737|M.marinum_M               --------------MKLALTP--------DEAAFRDELRTFYTTRIP---
MUL_3681|M.ulcerans_Agy99           --------------MKLALTP--------DEAAFRDELRTFYTTRIP---
MLBr_00737|M.leprae_Br4923          -------------MVGWSGNP--------LFDLFKLPEEHNELRATIRAL
                                                                     .:   .           

Mb3590c|M.bovis_AF2122/97           AALKGLGGPGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHR
Rv3560c|M.tuberculosis_H37Rv        AALKGLGGPGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHR
MAB_0597|M.abscessus_ATCC_1997      AELKGLGGPGSEHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQR
Mvan_4956|M.vanbaalenii_PYR-1       ADWRDTQTGVGDEEFVRFQKAWFAELHSAGYAVPHWPAEWGG-GLPVDRQ
Mflv_1794|M.gilvum_PYR-GCK          ADWRAAQSGVGEEEFVRFQKAWFAELHSAGYAVPHWPAQWGG-GLPVDKQ
MSMEG_5619|M.smegmatis_MC2_155      KDWRAAQTGVSDDEFAAFQKAWFAELHSAGYAVPHWPAEWGG-GMSVPQQ
TH_3515|M.thermoresistible__bu      KDWRAAQTNVSDDDFVAFQQAWFAELHRAGYAVPHWPAEWGG-GMPVDRQ
MAV_2619|M.avium_104                AEPRPRD----DAGIREYDLAWQRTQAEGGWAGIAWPTEYGGKGLTLLQQ
MMAR_3737|M.marinum_M               EDLRELVRQ-GQSPSRDEIVTCHKILNDHGLAVPNWPVEWGGKDWTPTQH
MUL_3681|M.ulcerans_Agy99           EDLRELVRQ-GQSPSRDEIVTCHKILNDHGLAVPNWPVEWGGKDWTPTQH
MLBr_00737|M.leprae_Br4923          AEKEIAPHAADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAA
                                       .                         *      * : ** .      

Mb3590c|M.bovis_AF2122/97           VAFYEEYARADAP-DKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTE
Rv3560c|M.tuberculosis_H37Rv        VAFYEEYARADAP-DKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTE
MAB_0597|M.abscessus_ATCC_1997      VIFYEEYARAEAP-HKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTE
Mvan_4956|M.vanbaalenii_PYR-1       VVLYQELAAHDAPRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGE-
Mflv_1794|M.gilvum_PYR-GCK          VVLYQELAAHDAPRLVLAFVGIHHAASTLLVAGTEEQRRRHLPAILDGE-
MSMEG_5619|M.smegmatis_MC2_155      IVLYSELAAHDAPRLVLAFVGIHHAASTLLAAGTDAQRNRHLPAILDGE-
TH_3515|M.thermoresistible__bu      IVLYSELAAHDAPRLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGE-
MAV_2619|M.avium_104                LIWYEEYAARGFPGIDACFVGNSHAGPTLITRATDEQKSFHLPKILGGEV
MMAR_3737|M.marinum_M               QIWADEMQLASVP--EPLNFNTKMVGPVIAEFGSQEIKQRFLPPTASLDI
MUL_3681|M.ulcerans_Agy99           QIWADEMQLASVP--EPLNFNTKMVGPVIAEFGSQEIKQRFLPPTASLDI
MLBr_00737|M.leprae_Br4923          CIVIEEVARVDAS-ASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGA
                                        .*      .               :   .:   :   **       

Mb3590c|M.bovis_AF2122/97           LWCQGYSEPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVL
Rv3560c|M.tuberculosis_H37Rv        LWCQGYSEPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVL
MAB_0597|M.abscessus_ATCC_1997      LWCQGYSEPGAGSDLANVSTSAVLDGGDWVINGQKVWTSLALQSQWCFVV
Mvan_4956|M.vanbaalenii_PYR-1       IWVQGFSEPEAGSDLAALRTTARRAGDEFVVNGQKLWASGGMHADWCLLL
Mflv_1794|M.gilvum_PYR-GCK          IWVQGFSEPEAGSDLAALRTSARRVGDEFIVNGQKLWASGGMHADWCLLL
MSMEG_5619|M.smegmatis_MC2_155      IWVQGFSEPEAGSDLASLRTTARAEGDTFVVNGQKLWASGAMYADWCLLL
TH_3515|M.thermoresistible__bu      IWVQGFSEPEAGSDLASLRTTARRDGDRFIVNGQKLWASGAKHADWCLLL
MAV_2619|M.avium_104                IWCQGFSEPDAGSDLAALRTKAVVDGEDLVVSGQKLWTSFATVADYQELL
MMAR_3737|M.marinum_M               WWCQGFSEPEAGSDLASLRTTAVRDGDSYVVNGQKTWTTLGQYADWIFCL
MUL_3681|M.ulcerans_Agy99           WWCQGFSEPEAGSDLASLRTTAVRDGDSYVVNGQKTWTTLGQYADWIFCL
MLBr_00737|M.leprae_Br4923          MASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVM
                                        . **  **** * : * *   *   ::.* * * : .  : :   :

Mb3590c|M.bovis_AF2122/97           ARTEKGSQRH------AGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEV
Rv3560c|M.tuberculosis_H37Rv        ARTEKGSQRH------AGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEV
MAB_0597|M.abscessus_ATCC_1997      ARTEPGSSRH------KGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEV
Mvan_4956|M.vanbaalenii_PYR-1       ARTDPDAPKRPGARKSAGISYFLMDMTTPGVDVRPIRNAIGD--SHFCEI
Mflv_1794|M.gilvum_PYR-GCK          ARTDPDAPKR------KGISYFLLDMTSPGVDVRPIRNAIGD--SHFCEI
MSMEG_5619|M.smegmatis_MC2_155      ARTDPNAPKR------HGISYFMMDMKTPGVDVRPIRNAVGD--SHFCEI
TH_3515|M.thermoresistible__bu      ARTDPDAPKR------HGISYFLLDMTTPGVEVRPIRNAIGD--SHFCEI
MAV_2619|M.avium_104                VRTDNTGSKH------KGITWVICDMSTPGIDVRPIETIEGG--SEFCEV
MMAR_3737|M.marinum_M               VRTDPQAPKR-----QAGISFLLIDMATPGITLRPIKTIDGG--HEVNEV
MUL_3681|M.ulcerans_Agy99           VRTDPQAPKR-----QAGISFLLIDMATPGITLRPIKTIDGG--HEVNEV
MLBr_00737|M.leprae_Br4923          AVTDPDKGAN-------GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTEL
                                    . *:     .       *:: .:      *. : *     *       *:

Mb3590c|M.bovis_AF2122/97           FFDDARTDADLVVGAPGDGWRVAMATLTFERGVSTLGQQIVYARELSNLV
Rv3560c|M.tuberculosis_H37Rv        FFDDARTDADLVVGAPGDGWRVAMATLTFERGVSTLGQQIVYARELSNLV
MAB_0597|M.abscessus_ATCC_1997      FFDNARTSADLVVGEPGDGWRVAMGTLTFERGVSTLGNQITYARELSRLA
Mvan_4956|M.vanbaalenii_PYR-1       FLDDVRIPAANLIGAENNGWQVAQATLGAERGLTMLELAERLGNAGFRWL
Mflv_1794|M.gilvum_PYR-GCK          FLDDVRIPATNLIGAENAGWQVAQETLGAERGMTMLELAERLGNAGFRWL
MSMEG_5619|M.smegmatis_MC2_155      FLNDVVIPSANLVGPVNKGWQVAQATLGAERGMTMLELAERLGNAGFRWL
TH_3515|M.thermoresistible__bu      FLNDVVIPETNLVGRENQGWQVAQATLGAERGLTMLELAERLGTAGFRWL
MAV_2619|M.avium_104                FYDDVRIPLSNVVGDVGEGWSVAMATLSFERGTAFTANQVRLAKIIEDLI
MMAR_3737|M.marinum_M               FFSDVRVPADQLVGQENQGWTYAKFLLGNER--TGIAGVGRTKVRLAEVK
MUL_3681|M.ulcerans_Agy99           FFSDVRVPADQLVGQENQGWTYAKFLLGNER--TGIAGVGRTKVRLAEVK
MLBr_00737|M.leprae_Br4923          YFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAI
                                    : ..       ::*  . *:  *   *   *                   

Mb3590c|M.bovis_AF2122/97           ELARRTAAAD-------DPLIRERLTRAWTGLRAMRSYALATMEGP--AV
Rv3560c|M.tuberculosis_H37Rv        ELARRTAAAD-------DPLIRERLTRAWTGLRAMRSYALATMEGP--AV
MAB_0597|M.abscessus_ATCC_1997      ELAKSNGAAD-------DPAIRERLAQAYVGMRTMRAYALATMD-----E
Mvan_4956|M.vanbaalenii_PYR-1       V-QSAPVD---------DPIVADRLAGFETEITGLRGLCRQIVER---GA
Mflv_1794|M.gilvum_PYR-GCK          V-ESAPVD---------DPIVADRLAGFETELAALRGMCRRMVEH---GP
MSMEG_5619|M.smegmatis_MC2_155      VDACSPVD---------DPVVADRLAQFEIELTGLRGLCRDLVERSETGE
TH_3515|M.thermoresistible__bu      V-AQSPVD---------DPVVADRLAQFEVELTALRGMCRDLVLDAEAGA
MAV_2619|M.avium_104                DYARDHVGPDGRRPAIADDDIARRLARARASVASLRALTYTNICEAMKTE
MMAR_3737|M.marinum_M               KHAANNGLLD-------DPLFAARLAEAENELLALELTQARVVTDSADGK
MUL_3681|M.ulcerans_Agy99           KHAANNGLLD-------DPLFAARLAEAENELLALELTQARVVTDSADGK
MLBr_00737|M.leprae_Br4923          VYTKDRKQFG-------ESISTFQSIQFMLADMAMKVEAARLIVYAAAAR
                                                     :     :          :.      :       

Mb3590c|M.bovis_AF2122/97           EQPGQDNVSKLLWANWHRNLGELAMDVIGK------PGMTMPDGEFDEWQ
Rv3560c|M.tuberculosis_H37Rv        EQPGQDNVSKLLWANWHRNLGELAMDVIGK------PGMTMPDGEFDEWQ
MAB_0597|M.abscessus_ATCC_1997      ERPGQDNVSKLLWANWHRDLGELAMEIIGT------STLLTNAGEMDEWQ
Mvan_4956|M.vanbaalenii_PYR-1       TGPADASVVKLYYSELLQRLTDFAVEIGGPEAHTVLAKPMSSGWESGSWV
Mflv_1794|M.gilvum_PYR-GCK          SGPADPSVVKLYYSELLQRLTDFGAEIGGLPAHTVLTKPMSSGWESGSWV
MSMEG_5619|M.smegmatis_MC2_155      AGPADASIVKLYYSELLQRMTDFGAQIAGLPAHTVLTKPASSGWESGAWM
TH_3515|M.thermoresistible__bu      VGPADASIVKLYYSELLQRMTDFGAEVAGLPAHTQLAKPVSSGWESGSWV
MAV_2619|M.avium_104                TPGPRGSIVKLMYAELAKEIGRLAMDVVGP-----ASVRYSSRWDVDGWV
MMAR_3737|M.marinum_M               PNPAS-SVLKLRGSQLQQVATELLVEVAGPDALP-VGGAQAAGIASPQWA
MUL_3681|M.ulcerans_Agy99           PNPAS-SVLKLRGSQLQQVATELLVEVAGPDALP-VGGAQAAGIASPQWA
MLBr_00737|M.leprae_Br4923          AERGEPDLGFIS-AASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFM
                                          .:  :  :        :  ::                     : 

Mb3590c|M.bovis_AF2122/97           R----LYLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG-
Rv3560c|M.tuberculosis_H37Rv        R----LYLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG-
MAB_0597|M.abscessus_ATCC_1997      R----LFLFSRADTIYGGSNEIQRNIISERVLGLPREAR--
Mvan_4956|M.vanbaalenii_PYR-1       L----DFVGSWEWTIPGGASEIQRTIIAERGLGLPREPGAA
Mflv_1794|M.gilvum_PYR-GCK          L----DFVGSWEWTIPGGASEIQRTIIGERGLGLPREPSAL
MSMEG_5619|M.smegmatis_MC2_155      L----DFIGSWEWTIPGGASEIQRTIIGERGLGLPREPSAV
TH_3515|M.thermoresistible__bu      L----DFIGSWEWTIPGGSSEIQRTIIAERGLGLPREPSVA
MAV_2619|M.avium_104                G----YYYYSFSQAIGGGTSEIQRNIVGERVLGLPR-----
MMAR_3737|M.marinum_M               QSSAPRYLNYRKTSIYGGSNEVQRNIIASTILGL-------
MUL_3681|M.ulcerans_Agy99           QSSAPRYLNYRKTSIYGGSNEVQRNIIASTILGL-------
MLBr_00737|M.leprae_Br4923          R-------DAKITQIYEGTNQIQRVVMSRALLR--------
                                                  *  *:.::** ::.   *

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_4956	-	-	100% (404)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4006	-	3e-62	38.39% (409)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4379	-	1e-61	40.15% (401)	acyl-CoA dehydrogenase domain-containing protein