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M. vanbaalenii PYR-1 Mvan_4379 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 4699166 - 4700323
length: 385

MQLALTAEEAAFRDELRTFYRTKIPAEIRERTRSGTEANRDDIVTANKILNDHGLMVPNWPVEWGGKDWT
PIQHQIWLDEMQLASVPEPLTFNAKMVGPVIAEFGSQELKERFLPPTAAVDIWWCQGFSEPEAGSDLASL
RTTALRDGDSYVVNGQKTWTTLGQYADWIFCLVRTDPDAPKKQAGISFLLIDMNTPGITLRPIKLIDGSY
EVNEVFFEDVRVPADQLVGEENQGWSYAKFLLGNERTGITQIGRTKLRLSEVKERAKASGLLDDPLFAAR
LAETENDVLALELTQMRVASGSKDGKPNPASSVLKLRASELQQAATELLVEVAGADALPFGSHGIASADW
AQDAAPRYLNYRKTSIYGGSNEVQRTIIASTILGL

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_4379 - - 100% (385) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_1965 - 1e-75 40.15% (411) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4956 - 1e-61 39.75% (400) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 2e-55 37.50% (344) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_2287 - 0.0 96.10% (385) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 2e-55 37.50% (344) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 7e-26 28.16% (348) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_2495 - 4e-76 41.22% (410) acyl-CoA dehydrogenase
M. marinum M MMAR_3737 fadE17_1 0.0 81.96% (388) acyl-CoA dehydrogenase FadE17_1
M. avium 104 MAV_1766 - 0.0 80.57% (386) acyl-CoA dehydrogenase domain-containing protein
M. smegmatis MC2 155 MSMEG_6511 - 0.0 83.38% (385) acyl-CoA dehydrogenase domain-containing protein
M. thermoresistible (build 8) TH_3063 - 1e-177 77.98% (386) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_3681 fadE17_1 0.0 81.96% (388) acyl-CoA dehydrogenase FadE17_1

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           ---------------MQDVEEFRAQVRGWLADNLAGEFAALKGLGGPGRE
Rv3560c|M.tuberculosis_H37Rv        ---------------MQDVEEFRAQVRGWLADNLAGEFAALKGLGGPGRE
Mvan_4379|M.vanbaalenii_PYR-1       ----------MQLALTAEEAAFRDELRTFYRTKIPAEIRERTRSG----T
Mflv_2287|M.gilvum_PYR-GCK          ----------MQLALTPEEAEFRDELRNFYRTKIPAEIRERTRTG----S
MMAR_3737|M.marinum_M               ----------MKLALTPDEAAFRDELRTFYTTRIPEDLRELVRQGQ---S
MUL_3681|M.ulcerans_Agy99           ----------MKLALTPDEAAFRDELRTFYTTRIPEDLRELVRQGQ---S
MAV_1766|M.avium_104                ----------MQLALTPEEAAFRDELRTIYTTKIPEELRERVRRGS---A
MSMEG_6511|M.smegmatis_MC2_155      ----------MQLALTPEEAAFRDELRTFYRTEIPEDIRARHAKG----G
TH_3063|M.thermoresistible__bu      ----------VKLALSDADAAFRAEMREFFTTEIPADIRDRMRAG----R
MAB_2495|M.abscessus_ATCC_1997      ----------MDLAFSAEEEQFRTEVREFLDANLTAELRAAGRLQTS--V
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRAR----
                                                         :*  :*     .:. .             

Mb3590c|M.bovis_AF2122/97           HEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARADA
Rv3560c|M.tuberculosis_H37Rv        HEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARADA
Mvan_4379|M.vanbaalenii_PYR-1       EANRDDIVTANKILNDHGLMVPNWPVEWGGKDWTPIQHQIWLDEMQLASV
Mflv_2287|M.gilvum_PYR-GCK          EANRDDIVTANKILNDHGLMVPNWPVEWGGKDWTPIQHQIWLDEMQLASV
MMAR_3737|M.marinum_M               PS-RDEIVTCHKILNDHGLAVPNWPVEWGGKDWTPTQHQIWADEMQLASV
MUL_3681|M.ulcerans_Agy99           PS-RDEIVTCHKILNDHGLAVPNWPVEWGGKDWTPTQHQIWADEMQLASV
MAV_1766|M.avium_104                EVNRDDIVTSHKILHEHGLAVPNWPVEWGGKDWTPTQHQIWADEMQLACV
MSMEG_6511|M.smegmatis_MC2_155      ELLKDDIVTTHKILHKHGLAVPNWPVEWGGKDWTPTQHQIWLDEMQLACV
TH_3063|M.thermoresistible__bu      PRYPDDIVTTQRILNAHGLAVPNWPVEWGGRDWSPLQRQIWSDEMQLAAV
MAB_2495|M.abscessus_ATCC_1997      YSDHEASMRWQAILHRKGWAAPAWPVKYGGQPWSLAQHYIFSVESMVAGA
MLBr_00737|M.leprae_Br4923          -----FPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDA
                                                 *   *      * : **:            *   . .

Mb3590c|M.bovis_AF2122/97           PDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAGS
Rv3560c|M.tuberculosis_H37Rv        PDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAGS
Mvan_4379|M.vanbaalenii_PYR-1       PEPLT-FNAKMVGPVIAEFGSQELKERFLPPTAAVDIWWCQGFSEPEAGS
Mflv_2287|M.gilvum_PYR-GCK          PEPLT-FNAKMVGPVIAEFGSQEIKERFLPPTAAVDIWWCQGFSEPEAGS
MMAR_3737|M.marinum_M               PEPLN-FNTKMVGPVIAEFGSQEIKQRFLPPTASLDIWWCQGFSEPEAGS
MUL_3681|M.ulcerans_Agy99           PEPLN-FNTKMVGPVIAEFGSQEIKQRFLPPTASLDIWWCQGFSEPEAGS
MAV_1766|M.avium_104                PEPLN-FNTKMVGPVIAEFGSEEVKQRFLPPTASLDIWWCQGFSEPDAGS
MSMEG_6511|M.smegmatis_MC2_155      PEPLT-FNAKMIGPVIAEFASQEMKERFLPATAALDIFWCQGFSEPEAGS
TH_3063|M.thermoresistible__bu      PEPLA-FNANMVGPVIARFGSQQLKERFLPPTANLDIWWCQGFSEPEAGS
MAB_2495|M.abscessus_ATCC_1997      PSLSP-MGIRMVAHAIIKFGSPEQKEFFLPRILTGEVFFCQGYSEPESGS
MLBr_00737|M.leprae_Br4923          SASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGS
                                    .        .:    :   .: : :. .**         . . **  :**

Mb3590c|M.bovis_AF2122/97           DLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTE-KGSQRHAG
Rv3560c|M.tuberculosis_H37Rv        DLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTE-KGSQRHAG
Mvan_4379|M.vanbaalenii_PYR-1       DLASLRTTALRDGDSYVVNGQKTWTTLGQYADWIFCLVRTDPDAPKKQAG
Mflv_2287|M.gilvum_PYR-GCK          DLASLRTTALRDGDSYVVNGQKTWTTLGQYADWIFCLVRTDPNAPKKQAG
MMAR_3737|M.marinum_M               DLASLRTTAVRDGDSYVVNGQKTWTTLGQYADWIFCLVRTDPQAPKRQAG
MUL_3681|M.ulcerans_Agy99           DLASLRTTAVRDGDSYVVNGQKTWTTLGQYADWIFCLVRTDPQAPKRQAG
MAV_1766|M.avium_104                DLASLRTTAVRDGDHYIVNGQKTWTTLGQYADWIFCLVRTDPQAPKRQAG
MSMEG_6511|M.smegmatis_MC2_155      DLASLRTTAVRDGDTYVVNGQKTWTTLGQYADWIFCLVRTDPQAPKRQAG
TH_3063|M.thermoresistible__bu      DLASLRTTAVRDGDSYVVNGQKTWTTLGQYADWIFLLARTDPDAPKRQAG
MAB_2495|M.abscessus_ATCC_1997      DLASLQMSAVADGDDFVLNGSKIWTTHAREANWMFALVRTT-KGPKKQLG
MLBr_00737|M.leprae_Br4923          DAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGAN--G
                                    * **:   *  *** :::** * * : .  : *   :. *  .   .  *

Mb3590c|M.bovis_AF2122/97           LSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVVGAPGD
Rv3560c|M.tuberculosis_H37Rv        LSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVVGAPGD
Mvan_4379|M.vanbaalenii_PYR-1       ISFLLIDMNTPGITLRPIKLIDGS--YEVNEVFFEDVRVPADQLVGEENQ
Mflv_2287|M.gilvum_PYR-GCK          ISFLLIDMNTPGITLRPIKLIDGS--YEVNEVFFEDVRVPADQLVGEENQ
MMAR_3737|M.marinum_M               ISFLLIDMATPGITLRPIKTIDGG--HEVNEVFFSDVRVPADQLVGQENQ
MUL_3681|M.ulcerans_Agy99           ISFLLIDMATPGITLRPIKTIDGG--HEVNEVFFSDVRVPADQLVGQENQ
MAV_1766|M.avium_104                ISFLLFDMKSPGITLRPIKTIDGG--HEINEVFFEDVRVPADQLVGEENQ
MSMEG_6511|M.smegmatis_MC2_155      ISMLLIDLDTPGITMRPIKLVDGS--VEVNEVFFEDVRVPADQLVGEENQ
TH_3063|M.thermoresistible__bu      ISFLLADMNTPGITLRPIKLIDGG--HEVNEVFFEDVRIPADQLVGEENH
MAB_2495|M.abscessus_ATCC_1997      ITFILIDFTSPGIDVKPLVMSSGE--EVQNVVFFDNVRVPRANVLGEVDQ
MLBr_00737|M.leprae_Br4923          ISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGT
                                    :: ::      *. : *     *      . ::*.. *     ::*  . 

Mb3590c|M.bovis_AF2122/97           GWRVAMATLTFERGVS---TLGQQIVYARELSNLVELARRTAAADDPLIR
Rv3560c|M.tuberculosis_H37Rv        GWRVAMATLTFERGVS---TLGQQIVYARELSNLVELARRTAAADDPLIR
Mvan_4379|M.vanbaalenii_PYR-1       GWSYAKFLLGNERTG-----ITQIGRTKLRLSEVKERAKASGLLDDPLFA
Mflv_2287|M.gilvum_PYR-GCK          GWSYAKFLLGNERTG-----ITQIGRTKLKLAEVKERAKANGLFDDPLFA
MMAR_3737|M.marinum_M               GWTYAKFLLGNERTG-----IAGVGRTKVRLAEVKKHAANNGLLDDPLFA
MUL_3681|M.ulcerans_Agy99           GWTYAKFLLGNERTG-----IAGVGRTKVRLAEVKKHAANNGLLDDPLFA
MAV_1766|M.avium_104                GWTYAKFLLGNERTG-----IAGVGRTKVRLAEVKKHAAATGVLDDPLFA
MSMEG_6511|M.smegmatis_MC2_155      GWTYAKFLLGNERTG-----ITGVARTKVRLAQAKERAAANGLLNDPLFA
TH_3063|M.thermoresistible__bu      GWAYAKFLLSNERTG-----IARIGATKLWLSQVKSRAAECSLLDDPLFA
MAB_2495|M.abscessus_ATCC_1997      GWTVAKYLLEFERGGGAVAPMLQVGLDQLSVDARSVPAENGTLADDPVFC
MLBr_00737|M.leprae_Br4923          GFKTALATLDHTRPTIG---AQAVGIAQGALDAAIVYTKDRKQFGESIST
                                    *:  *   *   *                 :      :      .:.:  

Mb3590c|M.bovis_AF2122/97           ERLTRAWTGLRAMRSYALATMEGPAVE--QPGQDNVSKLLWANWHRNLGE
Rv3560c|M.tuberculosis_H37Rv        ERLTRAWTGLRAMRSYALATMEGPAVE--QPGQDNVSKLLWANWHRNLGE
Mvan_4379|M.vanbaalenii_PYR-1       ARLAETENDVLALELTQMRVASGSKDG-KPNPASSVLKLRASELQQAATE
Mflv_2287|M.gilvum_PYR-GCK          ARLAETENDVLALELTQMRVATGSKDG-KPNPASSVLKLRASELQQAATE
MMAR_3737|M.marinum_M               ARLAEAENELLALELTQARVVTDSADG-KPNPASSVLKLRGSQLQQVATE
MUL_3681|M.ulcerans_Agy99           ARLAEAENELLALELTQARVVTDSADG-KPNPASSVLKLRGSQLQQVATE
MAV_1766|M.avium_104                ARLAEAENELLALELTQSRVTTDSANG-QPNPASSVLKLRGSQLQQVATE
MSMEG_6511|M.smegmatis_MC2_155      ARLAEAENDVLALELTQMRVTSDSSDG-KPNPASSVLKLRGTQLQQLATE
TH_3063|M.thermoresistible__bu      ARIAELENDLLALELTQLRVSGSEGEG-KPNPASSILKLRGSQLQQAVTE
MAB_2495|M.abscessus_ATCC_1997      AKLADLAIRVDVLEVLEHRVLAVVAGGGNPGAASSMLKILGTELSQALTT
MLBr_00737|M.leprae_Br4923          FQSIQFMLADMAMKVEAARLIVYAAAA-RAERGEPDLGFISAASKCFASD
                                     :         .:.                   .    :  :        

Mb3590c|M.bovis_AF2122/97           LAMDVIG-----------------------KPGMTMPDGEFDEWQRLYLF
Rv3560c|M.tuberculosis_H37Rv        LAMDVIG-----------------------KPGMTMPDGEFDEWQRLYLF
Mvan_4379|M.vanbaalenii_PYR-1       LLVEVAGADALP----------------FGSHGIASADWAQDAAP-RYLN
Mflv_2287|M.gilvum_PYR-GCK          LLVEVAGADALP----------------FGTDSIASADWAQDAAP-RYLN
MMAR_3737|M.marinum_M               LLVEVAGPDALPVG-------------GAQAAGIASPQWAQSSAP-RYLN
MUL_3681|M.ulcerans_Agy99           LLVEVAGPDALPVG-------------GAQAAGIASPQWAQSSAP-RYLN
MAV_1766|M.avium_104                LLVEVAGPDALP----------------AKADDIASPSWAQSSAP-HYLN
MSMEG_6511|M.smegmatis_MC2_155      LLVEVAGADALP----------------CEAEGIASPEWAQLTAP-QYLN
TH_3063|M.thermoresistible__bu      LAVEVAGTDALP---------------YAAGDDIASPEWAQLAAP-RYLN
MAB_2495|M.abscessus_ATCC_1997      LTLEAAGPRGRAYQPHVTKPGGPVVEYTPPADGYHSGELWQAVAPLHYFN
MLBr_00737|M.leprae_Br4923          IAMEVTTDAVQLFG----------------GAGYTSDFPVERFMR----D
                                    : ::.                           .                 

Mb3590c|M.bovis_AF2122/97           TRADTIYGGSNEIQRNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv        TRADTIYGGSNEIQRNIIAERVLGLPREAKG
Mvan_4379|M.vanbaalenii_PYR-1       YRKTSIYGGSNEVQRTIIASTILGL------
Mflv_2287|M.gilvum_PYR-GCK          YRKTSIYGGSNEVQRTIIASTILGL------
MMAR_3737|M.marinum_M               YRKTSIYGGSNEVQRNIIASTILGL------
MUL_3681|M.ulcerans_Agy99           YRKTSIYGGSNEVQRNIIASTILGL------
MAV_1766|M.avium_104                YRKTSIYGGSSEVQRNIIASTILGL------
MSMEG_6511|M.smegmatis_MC2_155      YRKTSIYGGSNEVQRTIISSTILGL------
TH_3063|M.thermoresistible__bu      YRKTSIYGGTNEVQRTIIASTILGL------
MAB_2495|M.abscessus_ATCC_1997      DRAGSIYAGSNEIQRNILAKAQLGL------
MLBr_00737|M.leprae_Br4923          AKITQIYEGTNQIQRVVMSRALLR-------
                                     :   ** *:.::** :::   *

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_4379	-	-	100% (385)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_1965	-	1e-75	40.15% (411)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4956	-	1e-61	39.75% (400)	acyl-CoA dehydrogenase domain-containing protein