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M. thermoresistible (build 8) TH_3515 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 1451819 - 1452982
length: 388

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3515--100% (388)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4120-4e-7141.60% (387) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3935-1e-6740.97% (393) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1969cfadE172e-6440.20% (398) acyl-CoA dehydrogenase FADE17
M. gilvum PYR-GCKMflv_1794-0.082.34% (385) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1934cfadE172e-6440.20% (398) acyl-CoA dehydrogenase FADE17
M. leprae Br4923MLBr_00737fadE255e-2225.56% (356) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0597-1e-5735.68% (398) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_2862fadE179e-6238.40% (401) acyl-CoA dehydrogenase FadE17
M. avium 104MAV_2619-2e-7041.62% (394) acyl-CoA dehydrogenase domain-containing protein
M. smegmatis MC2 155MSMEG_5619-0.085.38% (383) acyl-CoA dehydrogenase domain-containing protein
M. ulcerans Agy99MUL_3681fadE17_11e-6141.67% (396) acyl-CoA dehydrogenase FadE17_1
M. vanbaalenii PYR-1Mvan_4956-0.081.44% (388) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3515|M.thermoresistible__bu      ---MTG-------------LDEFRDEVRTWCAEHIPKDW-RAAQTNVSDD
MSMEG_5619|M.smegmatis_MC2_155      ---MTHPEN----------LDDFRATVRDWCAAHVPKDW-RAAQTGVSDD
Mflv_1794|M.gilvum_PYR-GCK          ---MSELET-------------FRAEVRDWCREHVPADW-RAAQSGVGEE
Mvan_4956|M.vanbaalenii_PYR-1       --MTAESEDQRDNPTDSQSQAQFRQQVRAWCRDHIPADW-RDTQTGVGDE
MAV_2619|M.avium_104                ---MDLDFTP--------DQLEFRDQVRTWLDENKPAEP-RPRD----DA
Mb1969c|M.bovis_AF2122/97           ---MDVSYPPEAEAFRDR--------IREFVAEHLPPGWPGPGAL--PPH
Rv1934c|M.tuberculosis_H37Rv        ---MDVSYPPEAEAFRDR--------IREFVAEHLPPGWPGPGAL--PPH
MMAR_2862|M.marinum_M               ---MDVAYPPEAEEFRER--------VRAFLDEHLPCGWSGPGAL--AVQ
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MUL_3681|M.ulcerans_Agy99           ---MKLALTP--------DEAAFRDELRTFYTTRIPEDLRELVRQGQSPS
MLBr_00737|M.leprae_Br4923          --MVGWSGNP------LFDLFKLPEEHNELRATIRALAEKEIAPHAADVD
                                                               .                      

TH_3515|M.thermoresistible__bu      DFVAFQQ--AWFAELHRAGYAVPHWPAEWGG-GMPVDRQIVLYSELAAHD
MSMEG_5619|M.smegmatis_MC2_155      EFAAFQK--AWFAELHSAGYAVPHWPAEWGG-GMSVPQQIVLYSELAAHD
Mflv_1794|M.gilvum_PYR-GCK          EFVRFQK--AWFAELHSAGYAVPHWPAQWGG-GLPVDKQVVLYQELAAHD
Mvan_4956|M.vanbaalenii_PYR-1       EFVRFQK--AWFAELHSAGYAVPHWPAEWGG-GLPVDRQVVLYQELAAHD
MAV_2619|M.avium_104                GIREYDL--AWQRTQAEGGWAGIAWPTEYGGKGLTLLQQLIWYEEYAARG
Mb1969c|M.bovis_AF2122/97           EREEFAR--HWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
Rv1934c|M.tuberculosis_H37Rv        EREEFAR--HWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
MMAR_2862|M.marinum_M               DRKAFAA--RWRQLLVAAGLIAVSWPKEYGGGGYSPVEQVVLAEEFARAG
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MUL_3681|M.ulcerans_Agy99           RDEIVTC----HKILNDHGLAVPNWPVEWGGKDWTPTQHQIWADEMQLAS
MLBr_00737|M.leprae_Br4923          QRARFPE--EALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                                      *      * : ** .       :  .*     

TH_3515|M.thermoresistible__bu      AP-RLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGE-IWVQGFSEPE
MSMEG_5619|M.smegmatis_MC2_155      AP-RLVLAFVGIHHAASTLLAAGTDAQRNRHLPAILDGE-IWVQGFSEPE
Mflv_1794|M.gilvum_PYR-GCK          AP-RLVLAFVGIHHAASTLLVAGTEEQRRRHLPAILDGE-IWVQGFSEPE
Mvan_4956|M.vanbaalenii_PYR-1       AP-RLVLAFVGIHHAASTLLVAGTDEQRRRHLPAILDGE-IWVQGFSEPE
MAV_2619|M.avium_104                FP-GIDACFVGNSHAGPTLITRATDEQKSFHLPKILGGEVIWCQGFSEPD
Mb1969c|M.bovis_AF2122/97           APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
Rv1934c|M.tuberculosis_H37Rv        APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
MMAR_2862|M.marinum_M               APEREENDLFGVDLLGNTLIALGTEAQKRHFLPRILTGDDRWCQGFSEPE
MAB_0597|M.abscessus_ATCC_1997      APHKVNH--LGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPG
MUL_3681|M.ulcerans_Agy99           VP---EPLNFNTKMVGPVIAEFGSQEIKQRFLPPTASLDIWWCQGFSEPE
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMG--LILRGSEELKKQVLPSLAAEGAMASYALSERE
                                     .             .  :   .:   :   **           . **  

TH_3515|M.thermoresistible__bu      AGSDLASLRTTARRDGDRFIVNGQKLWASGAKHADWCLLLARTDPDAPKR
MSMEG_5619|M.smegmatis_MC2_155      AGSDLASLRTTARAEGDTFVVNGQKLWASGAMYADWCLLLARTDPNAPKR
Mflv_1794|M.gilvum_PYR-GCK          AGSDLAALRTSARRVGDEFIVNGQKLWASGGMHADWCLLLARTDPDAPKR
Mvan_4956|M.vanbaalenii_PYR-1       AGSDLAALRTTARRAGDEFVVNGQKLWASGGMHADWCLLLARTDPDAPKR
MAV_2619|M.avium_104                AGSDLAALRTKAVVDGEDLVVSGQKLWTSFATVADYQELLVRTDNTGSKH
Mb1969c|M.bovis_AF2122/97           AGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAKH
Rv1934c|M.tuberculosis_H37Rv        AGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAKH
MMAR_2862|M.marinum_M               AGSDLASVRTRAVLDGDQWVINGQKIWTSAGSTANWIFVLARTDPVAPKH
MAB_0597|M.abscessus_ATCC_1997      AGSDLANVSTSAVLDGGDWVINGQKVWTSLALQSQWCFVVARTEPGSSRH
MUL_3681|M.ulcerans_Agy99           AGSDLASLRTTAVRDGDSYVVNGQKTWTTLGQYADWIFCLVRTDPQAPKR
MLBr_00737|M.leprae_Br4923          AGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGAN
                                    **** * : * .   *   ::.* * * : .  : :   :. *:     .

TH_3515|M.thermoresistible__bu      ------HGISYFLLDMTTPGVEVRPIRNAIGD--SHFCEIFLNDVVIPET
MSMEG_5619|M.smegmatis_MC2_155      ------HGISYFMMDMKTPGVDVRPIRNAVGD--SHFCEIFLNDVVIPSA
Mflv_1794|M.gilvum_PYR-GCK          ------KGISYFLLDMTSPGVDVRPIRNAIGD--SHFCEIFLDDVRIPAT
Mvan_4956|M.vanbaalenii_PYR-1       PGARKSAGISYFLMDMTTPGVDVRPIRNAIGD--SHFCEIFLDDVRIPAA
MAV_2619|M.avium_104                ------KGITWVICDMSTPGIDVRPIETIEGG--SEFCEVFYDDVRIPLS
Mb1969c|M.bovis_AF2122/97           ------RGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTSAG
Rv1934c|M.tuberculosis_H37Rv        ------RGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTSAG
MMAR_2862|M.marinum_M               ------QGLSLLLVPMDQPAVVVRPIVNAAGH--SLFNEVFFADARTGVA
MAB_0597|M.abscessus_ATCC_1997      ------KGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTSAD
MUL_3681|M.ulcerans_Agy99           -----QAGISFLLIDMATPGITLRPIKTIDGG--HEVNEVFFSDVRVPAD
MLBr_00737|M.leprae_Br4923          -------GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGD
                                           *:: .:      .. : *     *       *::  .      

TH_3515|M.thermoresistible__bu      NLVGRENQGWQVAQATLGAERGLTMLELAERLG------TAGFRWLV---
MSMEG_5619|M.smegmatis_MC2_155      NLVGPVNKGWQVAQATLGAERGMTMLELAERLG------NAGFRWLVD--
Mflv_1794|M.gilvum_PYR-GCK          NLIGAENAGWQVAQETLGAERGMTMLELAERLG------NAGFRWLV---
Mvan_4956|M.vanbaalenii_PYR-1       NLIGAENNGWQVAQATLGAERGLTMLELAERLG------NAGFRWLV---
MAV_2619|M.avium_104                NVVGDVGEGWSVAMATLSFERGTAFTANQVRLAKIIEDLIDYARDHVGPD
Mb1969c|M.bovis_AF2122/97           NVVGRVGDGWSTAMTLLGFERGSHIATAAIDFER----DLQRLCELAR--
Rv1934c|M.tuberculosis_H37Rv        NVVGRVGDGWSTAMTLLGFERGSHIATAAIDFER----DLQRLCELAR--
MMAR_2862|M.marinum_M               NVVGEVGSGWTAAMSLLGFERGAQATTGAIDFAR----DLSRLCDLAR--
MAB_0597|M.abscessus_ATCC_1997      LVVGEPGDGWRVAMGTLTFERGVSTLGNQITYAR----ELSRLAELAK--
MUL_3681|M.ulcerans_Agy99           QLVGQENQGWTYAKFLLGNERTGIAGVGRTKVR------LAEVKKHAAN-
MLBr_00737|M.leprae_Br4923          RIIGEPGTGFKTALATLDHTR-PTIGAQAVGIAQG---ALDAAIVYTK--
                                     ::*  . *:  *   *   *                         .   

TH_3515|M.thermoresistible__bu      -AQSPVDDPVVADRLAQFEVELTALRGMCRDLVLDAEAGAVGPADASIVK
MSMEG_5619|M.smegmatis_MC2_155      -ACSPVDDPVVADRLAQFEIELTGLRGLCRDLVERSETGEAGPADASIVK
Mflv_1794|M.gilvum_PYR-GCK          -ESAPVDDPIVADRLAGFETELAALRGMCRRMVEH---GPSGPADPSVVK
Mvan_4956|M.vanbaalenii_PYR-1       -QSAPVDDPIVADRLAGFETEITGLRGLCRQIVER---GATGPADASVVK
MAV_2619|M.avium_104                GRRPAIADDDIARRLARARASVASLRALTYTNICEAMKTETPGPRGSIVK
Mb1969c|M.bovis_AF2122/97           -DRGLHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITK
Rv1934c|M.tuberculosis_H37Rv        -DRGLHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITK
MMAR_2862|M.marinum_M               -ARGLDSDPRIRDRLAWCYSRTQIMRYRGYRSLTWALNGLLPGAEAAISK
MAB_0597|M.abscessus_ATCC_1997      -SNGAADDPAIRERLAQAYVGMRTMRAYALATMDEERPG-----QDNVSK
MUL_3681|M.ulcerans_Agy99           --NGLLDDPLFAARLAEAENELLALELTQARVVTDSADGK-PNPASSVLK
MLBr_00737|M.leprae_Br4923          -DRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLG-
                                           :                :.      :              :  

TH_3515|M.thermoresistible__bu      LYYSELLQRMTDFGAEVAGLPAHTQLAKP---------VSSGWESGSWVL
MSMEG_5619|M.smegmatis_MC2_155      LYYSELLQRMTDFGAQIAGLPAHTVLTKP---------ASSGWESGAWML
Mflv_1794|M.gilvum_PYR-GCK          LYYSELLQRLTDFGAEIGGLPAHTVLTKP---------MSSGWESGSWVL
Mvan_4956|M.vanbaalenii_PYR-1       LYYSELLQRLTDFAVEIGGPEAHTVLAKP---------MSSGWESGSWVL
MAV_2619|M.avium_104                LMYAELAKEIGRLAMDVVGP-----ASVR---------YSSRWDVDGWVG
Mb1969c|M.bovis_AF2122/97           VIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMD
Rv1934c|M.tuberculosis_H37Rv        VIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMD
MMAR_2862|M.marinum_M               VIWSEYFQRYTELAVEILGLDALCPSGPGNGEARVVPQAGTANSPACWMD
MAB_0597|M.abscessus_ATCC_1997      LLWANWHRDLGELAMEIIGTSTLLTN------------AGEMDE---WQR
MUL_3681|M.ulcerans_Agy99           LRGSQLQQVATELLVEVAGPDALPVGGAQAAG------IASPQWAQSSAP
MLBr_00737|M.leprae_Br4923          FISAASKCFASDIAMEVTTDAVQLFGGAG------------YTSDFPVER
                                    .  :        :  ::                                 

TH_3515|M.thermoresistible__bu      DFIGSWEWTIPGGSSEIQRTIIAERGLGLPREPSVA---
MSMEG_5619|M.smegmatis_MC2_155      DFIGSWEWTIPGGASEIQRTIIGERGLGLPREPSAV---
Mflv_1794|M.gilvum_PYR-GCK          DFVGSWEWTIPGGASEIQRTIIGERGLGLPREPSAL---
Mvan_4956|M.vanbaalenii_PYR-1       DFVGSWEWTIPGGASEIQRTIIAERGLGLPREPGAA---
MAV_2619|M.avium_104                YYYYSFSQAIGGGTSEIQRNIVGERVLGLPR--------
Mb1969c|M.bovis_AF2122/97           ELLYARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC
Rv1934c|M.tuberculosis_H37Rv        ELLYARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC
MMAR_2862|M.marinum_M               ELLYARAATIYAGSSQIQRNVIGEQLLGLPKEPRREAVH
MAB_0597|M.abscessus_ATCC_1997      LFLFSRADTIYGGSNEIQRNIISERVLGLPREAR-----
MUL_3681|M.ulcerans_Agy99           RYLNYRKTSIYGGSNEVQRNIIASTILGL----------
MLBr_00737|M.leprae_Br4923          FMRDAKITQIYEGTNQIQRVVMSRALLR-----------
                                             *  *:.::** ::.   *