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NDAPATGSTPETMLTEEVERARYERGAEMLARVDGEGGQRVVEALADIAPALAHHIVAYGFGDVYARPGL APAQRQLVTLGMLTALGGCEPQLDVHINASLNVGLTTSEIVEAIIHAAVYCGFPKALNAIFVAKRVFAER DLLPVASGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4934 | - | - | 100% (150) | carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_0563 | - | 2e-14 | 35.25% (139) | 4-carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_4821 | - | 4e-11 | 33.05% (118) | carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0794 | - | 1e-06 | 35.80% (81) | 4-carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_0527 | - | 2e-14 | 35.25% (139) | 4-carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv0771 | - | 1e-06 | 35.80% (81) | 4-carboxymuconolactone decarboxylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1221 | - | 3e-05 | 32.10% (81) | 4-carboxymuconolactone decarboxylase |
| M. marinum M | MMAR_4925 | - | 1e-06 | 40.00% (65) | 4-carboxymuconolactone decarboxylase |
| M. avium 104 | MAV_3552 | pcaC | 7e-12 | 36.00% (125) | hypothetical protein MAV_3552 |
| M. smegmatis MC2 155 | MSMEG_2604 | pcaC | 1e-11 | 34.00% (100) | 4-carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_0621 | - | 4e-13 | 48.10% (79) | 4-carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_0480 | - | 9e-07 | 40.00% (65) | 4-carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0527|M.gilvum_PYR-GCK MSNPPLTAIHLGGPDDGPLLLLGPSLGTTTATLWTGVAQRLVDHVRVVGW
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3552|M.avium_104 --------------------------------------------------
Mvan_4934|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK DLPGHGRGRRAHPFTIADLAAAVLVIADDLNVETFHYAGDSVGGCVGLQL
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3552|M.avium_104 --------------------------------------------------
Mvan_4934|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK LLDAPQRVSSATLLCTGAAIGTPDGWLARAATVRAGGVDTMLTGAAERWF
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3552|M.avium_104 --------------------------------------------------
Mvan_4934|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK APGFVDREPGTASALLDALSHTDAESYAQVCEALAVFDVTDRLSEIVTPV
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3552|M.avium_104 --------------------------------------------------
Mvan_4934|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK LAVAGSADSPTPPESLRRIASDVKDGDVVVLEGVGHLAPAEAPERVAGLI
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3552|M.avium_104 --------------------------------------------------
Mvan_4934|M.vanbaalenii_PYR-1 ------------------------------------------------MN
Mflv_0527|M.gilvum_PYR-GCK AEIVGVPQPPSKTLEDVHRAGMAVRREVLGHAHVD--RAVAGTTD-LTAD
MSMEG_2604|M.smegmatis_MC2_155 ---------MTTMRDETHAAGSQVRRAVLGDDHVD--RAVAATTG-FTAD
TH_0621|M.thermoresistible__bu ----------------MREQGLQVFRELLPGVLPD--GDVDFRDGSFGDE
Mb0794|M.bovis_AF2122/97 ------------MMDELRRTGLDKMNEVYAWDMPD--MPG---------E
Rv0771|M.tuberculosis_H37Rv ------------MMDELRRTGLDKMNEVYAWDMPD--MPG---------E
MMAR_4925|M.marinum_M -------------MDELRRKGLDKMNEVYGWEMPN--IEGD--------A
MUL_0480|M.ulcerans_Agy99 -------------MDELRRKGLDKMNEVYGWEMPN--IEGD--------A
MAB_1221|M.abscessus_ATCC_1997 ---MVCHTRKGQVMDELRRQGLDKMKEVYGWDMPD--IPG---------D
MAV_3552|M.avium_104 --------MSRSDSAARHQRGVRTFAEVMTFDPPD--DAS---------P
Mvan_4934|M.vanbaalenii_PYR-1 DAPATGSTPETMLTEEVERARYERGAEMLARVDGEGGQRVVEALADIAPA
. : :
Mflv_0527|M.gilvum_PYR-GCK FQHMITQYAWGSIWTRPGLDFRSRSMITLTALVARG-HHEELAMHLRAAR
MSMEG_2604|M.smegmatis_MC2_155 FQDLITRYAWGEIWTRPGLDRRSRSMITLTAMIARG-HHDELAMHVRAAR
TH_0621|M.thermoresistible__bu LLEIGIDNVFGRLWTRDGLSRRDRSLVTLGILIALR-ATDELRFHVQIAR
Mb0794|M.bovis_AF2122/97 FFALTVDHLFGRIWTRPGLSMRDRRMAVIAVLTAQG-QSDLLEVQVNAVL
Rv0771|M.tuberculosis_H37Rv FFALTVDHLFGRIWTRPGLSMRDRRMAVIAVLTAQG-QSDLLEVQVNAVL
MMAR_4925|M.marinum_M YFDLTVDHLFGTIWTRPGLSMRDRRLMTLTAVTAIG-NRDLAEIQINAAL
MUL_0480|M.ulcerans_Agy99 YFDLTVDHLFGTIWTRPGLSMRDRRLMTLTAVTAIG-NRDLAEIQINAAP
MAB_1221|M.abscessus_ATCC_1997 YFKYTIDHLFGTIWTRPELSMRDRRLLLLGAVSALG-LDEILEIQTSAAL
MAV_3552|M.avium_104 CASGLIDFVFGEVWSRPGLSRRDRRFVTLACVAAAD-AQAPLEQHVYAAL
Mvan_4934|M.vanbaalenii_PYR-1 LAHHIVAYGFGDVYARPGLAPAQRQLVTLGMLTALGGCEPQLDVHINASL
:* :::* * .* : : : * :
Mflv_0527|M.gilvum_PYR-GCK RNG-LSNDEIKELLLQTAIYCGVPDANSAFRIAAE----VLPEFDEHPGA
MSMEG_2604|M.smegmatis_MC2_155 RNG-LSVDEIKEVLLQSAIYCGVPEANTAFRIAGA----VLAEEAQEPGD
TH_0621|M.thermoresistible__bu NNG-LTEDEIAEVIYHATGYAGFPNASTAMKVAKE----VLAEEHSRAAD
Mb0794|M.bovis_AF2122/97 HNDELTIDELRELAVFITHYVGFPLGSRLNSAIER----VAAKRKQAAEN
Rv0771|M.tuberculosis_H37Rv HNDELTIDELRELAVFITHYVGFPLGSRLNSAIER----VAAKRKQAAEN
MMAR_4925|M.marinum_M LNGELTEAELKEMAVFLTHYLGFPLGSGLNGAVDT----VVARRKKAAAK
MUL_0480|M.ulcerans_Agy99 LNGELTEAELKEMAVFLTHYLGFPLGSGLNGAVDT----VVARRKKAAAK
MAB_1221|M.abscessus_ATCC_1997 KNGELTEAELREVAIFITHYVGWPLGQRVNKHVEM----AVAKQNEARR-
MAV_3552|M.avium_104 NSGDLSITEMREAVLHFAVYAGWPKASRFNIVVDQQWARIAAERGEPTPD
Mvan_4934|M.vanbaalenii_PYR-1 NVG-LTTSEIVEAIIHAAVYCGFPKALNAIFVAKR----VFAERDLLPVA
. *: *: * : * * * . ..
Mflv_0527|M.gilvum_PYR-GCK PS------------------------------------------------
MSMEG_2604|M.smegmatis_MC2_155 ER------------------------------------------------
TH_0621|M.thermoresistible__bu ADKQSRLGESNP--------------------------------------
Mb0794|M.bovis_AF2122/97 GSLPDTKANVAEVLAKESGKSS----------------------------
Rv0771|M.tuberculosis_H37Rv GSLPDTKANVAEVLAKESGKSS----------------------------
MMAR_4925|M.marinum_M GAGEDKKGNVDDALKMHSGGKPD---------------------------
MUL_0480|M.ulcerans_Agy99 GAGEDKKGNVDDALKMHSGSKPD---------------------------
MAB_1221|M.abscessus_ATCC_1997 -----TKESSDD--------------------------------------
MAV_3552|M.avium_104 PEPLLPLVTAADPEQRLRGGERSFKDINCLPFAPPRDNPYSGAGILNFVF
Mvan_4934|M.vanbaalenii_PYR-1 SGQ-----------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3552|M.avium_104 GEMWLRPGLGMKERRLITVACVAFQDAEIPIMSHVYAALKSGDVSFREMD
Mvan_4934|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK -----------------------------------------
MSMEG_2604|M.smegmatis_MC2_155 -----------------------------------------
TH_0621|M.thermoresistible__bu -----------------------------------------
Mb0794|M.bovis_AF2122/97 -----------------------------------------
Rv0771|M.tuberculosis_H37Rv -----------------------------------------
MMAR_4925|M.marinum_M -----------------------------------------
MUL_0480|M.ulcerans_Agy99 -----------------------------------------
MAB_1221|M.abscessus_ATCC_1997 -----------------------------------------
MAV_3552|M.avium_104 EVALQFAAYYGCAKADHLNQALAEQKQRVIAENHSDATPVG
Mvan_4934|M.vanbaalenii_PYR-1 -----------------------------------------