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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0621 | - | - | 100% (139) | 4-carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_1260 | - | 9e-14 | 30.83% (133) | POSSIBLE 4-CARBOXYMUCONOLACTONE DECARBOXYLASE (CMD) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0794 | - | 1e-12 | 32.00% (125) | 4-carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_0527 | - | 3e-15 | 44.71% (85) | 4-carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv0771 | - | 1e-12 | 32.00% (125) | 4-carboxymuconolactone decarboxylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1221 | - | 2e-12 | 34.85% (132) | 4-carboxymuconolactone decarboxylase |
| M. marinum M | MMAR_4925 | - | 8e-13 | 31.85% (135) | 4-carboxymuconolactone decarboxylase |
| M. avium 104 | MAV_0716 | pcaC | 1e-12 | 32.00% (125) | hypothetical protein MAV_0716 |
| M. smegmatis MC2 155 | MSMEG_6150 | - | 1e-46 | 78.63% (117) | 4-carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | MUL_0480 | - | 6e-13 | 31.85% (135) | 4-carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_0563 | - | 3e-15 | 44.71% (85) | 4-carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0621|M.thermoresistible__bu --------------------------------------------------
MSMEG_6150|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAV_0716|M.avium_104 --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK MSNPPLTAIHLGGPDDGPLLLLGPSLGTTTATLWTGVAQRLVDHVRVVGW
Mvan_0563|M.vanbaalenii_PYR-1 MSNPPLTAIHLGGPDDGPLLLLGPSLGTTTATLWTGVAQRLVDHVRVVGW
TH_0621|M.thermoresistible__bu --------------------------------------------------
MSMEG_6150|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAV_0716|M.avium_104 --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK DLPGHGRGRRAHPFTIADLAAAVLVIADDLNVETFHYAGDSVGGCVGLQL
Mvan_0563|M.vanbaalenii_PYR-1 DLPGHGRGRRAHPFTIADLAAAVLVIADDLNVETFHYAGDSVGGCVGLQL
TH_0621|M.thermoresistible__bu --------------------------------------------------
MSMEG_6150|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAV_0716|M.avium_104 --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK LLDAPQRVSSATLLCTGAAIGTPDGWLARAATVRAGGVDTMLTGAAERWF
Mvan_0563|M.vanbaalenii_PYR-1 LLDAPQRVSSATLLCTGAAIGTPDGWLARAATVRAGGVDTMLAGAAERWF
TH_0621|M.thermoresistible__bu --------------------------------------------------
MSMEG_6150|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAV_0716|M.avium_104 --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK APGFVDREPGTASALLDALSHTDAESYAQVCEALAVFDVTDRLSEIVTPV
Mvan_0563|M.vanbaalenii_PYR-1 APGFVDREPGTASALLDALSHTDAESYAQVCEALAVFDVTNQLSEIVTPV
TH_0621|M.thermoresistible__bu --------------------------------------------------
MSMEG_6150|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4925|M.marinum_M --------------------------------------------------
MUL_0480|M.ulcerans_Agy99 --------------------------------------------------
MAV_0716|M.avium_104 --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1221|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0527|M.gilvum_PYR-GCK LAVAGSADSPTPPESLRRIASDVKDGDVVVLEGVGHLAPAEAPERVAGLI
Mvan_0563|M.vanbaalenii_PYR-1 LAVAGSVDVPTPPESLRRIASDVKDGDLVVLEGVGHLAPAEAPQRVAGLI
TH_0621|M.thermoresistible__bu --------MREQGLQVFRELLPGVLPDGDVDFRDG-------SFGDELLE
MSMEG_6150|M.smegmatis_MC2_155 --------MREKGFQVLRELLPDLPLDG--FQRDG-------SFGDELLE
MMAR_4925|M.marinum_M -------------MDELRRKGLDKMNEVYGWEMPN-------IEGDAYFD
MUL_0480|M.ulcerans_Agy99 -------------MDELRRKGLDKMNEVYGWEMPN-------IEGDAYFD
MAV_0716|M.avium_104 ------------MMDERRRKGLEKMNEVYGWEMPN-------VEGDAYFD
Mb0794|M.bovis_AF2122/97 ------------MMDELRRTGLDKMNEVYAWDMPD-------MPG-EFFA
Rv0771|M.tuberculosis_H37Rv ------------MMDELRRTGLDKMNEVYAWDMPD-------MPG-EFFA
MAB_1221|M.abscessus_ATCC_1997 ---MVCHTRKGQVMDELRRQGLDKMKEVYGWDMPD-------IPG-DYFK
Mflv_0527|M.gilvum_PYR-GCK AEIVGVPQPPSKTLEDVHRAGMAVRREVLGHAHVDRAVAGTTDLTADFQH
Mvan_0563|M.vanbaalenii_PYR-1 AEIVGVPQPPSKTLEDVHRAGMAVRREVLGEAHVDRAVAGTTDLTADFQH
:: :. : .
TH_0621|M.thermoresistible__bu IGIDNVFGRLWTRDGLSRRDRSLVTLGILIALRATDELRFHVQIARNNG-
MSMEG_6150|M.smegmatis_MC2_155 IGLDNVFGRLWSREGLSRRDRSLVTMGILIALRATDEFASHVKIARNNG-
MMAR_4925|M.marinum_M LTVDHLFGTIWTRPGLSMRDRRLMTLTAVTAIGNRDLAEIQINAALLNGE
MUL_0480|M.ulcerans_Agy99 LTVDHLFGTIWTRPGLSMRDRRLMTLTAVTAIGNRDLAEIQINAAPLNGE
MAV_0716|M.avium_104 LTVDHLFGSIWTRPGLSMRDKRIMTLTAVTAIGNRDLAEIQINAALLNGE
Mb0794|M.bovis_AF2122/97 LTVDHLFGRIWTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDE
Rv0771|M.tuberculosis_H37Rv LTVDHLFGRIWTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDE
MAB_1221|M.abscessus_ATCC_1997 YTIDHLFGTIWTRPELSMRDRRLLLLGAVSALGLDEILEIQTSAALKNGE
Mflv_0527|M.gilvum_PYR-GCK MITQYAWGSIWTRPGLDFRSRSMITLTALVARGHHEELAMHLRAARRNG-
Mvan_0563|M.vanbaalenii_PYR-1 MITQYAWGTIWTRPGLDLRSRSMITLTALVARGHHEELAMHLRAARRNG-
: :* :*:* *. *.: : : : * : : . *.
TH_0621|M.thermoresistible__bu LTEDEIAEVIYHATGYAGFPNASTAMKVAKEVLAEEHSRAADADKQSRLG
MSMEG_6150|M.smegmatis_MC2_155 LTEQEIAEVIYHSSGYAGFPNANTAMKVAKGVLEGP--------------
MMAR_4925|M.marinum_M LTEAELKEMAVFLTHYLGFPLGSGLNGAVDTVVARRKKAAAKGAGEDKKG
MUL_0480|M.ulcerans_Agy99 LTEAELKEMAVFLTHYLGFPLGSGLNGAVDTVVARRKKAAAKGAGEDKKG
MAV_0716|M.avium_104 LTETELKEMAVFLTHYLGFPLGSALNGAVDAVVAKRRKAAAKGAGEDKKA
Mb0794|M.bovis_AF2122/97 LTIDELRELAVFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPDTKA
Rv0771|M.tuberculosis_H37Rv LTIDELRELAVFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPDTKA
MAB_1221|M.abscessus_ATCC_1997 LTEAELREVAIFITHYVGWPLGQRVNKHVEMAVAKQNEARR------TKE
Mflv_0527|M.gilvum_PYR-GCK LSNDEIKELLLQTAIYCGVPDANSAFRIAAEVLPEFDEHPGAPS------
Mvan_0563|M.vanbaalenii_PYR-1 LSNDEIKELLMQTAIYCGVPDANSAFRIAAEVLPEFDEHPGAPS------
*: *: *: : * * * .. .
TH_0621|M.thermoresistible__bu ESNP-----------
MSMEG_6150|M.smegmatis_MC2_155 ---------------
MMAR_4925|M.marinum_M NVDDALKMHSGGKPD
MUL_0480|M.ulcerans_Agy99 NVDDALKMHSGSKPD
MAV_0716|M.avium_104 NVDAALKMHSGGERG
Mb0794|M.bovis_AF2122/97 NVAEVLAKESGKSS-
Rv0771|M.tuberculosis_H37Rv NVAEVLAKESGKSS-
MAB_1221|M.abscessus_ATCC_1997 SSDD-----------
Mflv_0527|M.gilvum_PYR-GCK ---------------
Mvan_0563|M.vanbaalenii_PYR-1 ---------------