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MDPQTYELGRQIRTTVLGADYVQRAASDADDFSQPLQDLVTEYCWGAVWGRDGLPLKTRSMLNLAMIAVL NRPQELATHIRGALNNGVTRDEIREIFLQVGIYAGIPAAVDSFRVAKTAFAELEAE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4821 | - | - | 100% (126) | carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_0563 | - | 8e-24 | 37.82% (119) | 4-carboxymuconolactone decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_4934 | - | 3e-11 | 33.05% (118) | carboxymuconolactone decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0794 | - | 1e-05 | 27.71% (83) | 4-carboxymuconolactone decarboxylase |
| M. gilvum PYR-GCK | Mflv_1912 | - | 2e-55 | 80.16% (126) | carboxymuconolactone decarboxylase |
| M. tuberculosis H37Rv | Rv0771 | - | 1e-05 | 27.71% (83) | 4-carboxymuconolactone decarboxylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3552 | pcaC | 5e-09 | 32.00% (100) | hypothetical protein MAV_3552 |
| M. smegmatis MC2 155 | MSMEG_2604 | pcaC | 7e-26 | 42.62% (122) | 4-carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_0621 | - | 3e-13 | 37.36% (91) | 4-carboxymuconolactone decarboxylase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0794|M.bovis_AF2122/97 ----MMDELRRTGLDKMNEVYAWDMPD---------MPGEFFALTVDHLF
Rv0771|M.tuberculosis_H37Rv ----MMDELRRTGLDKMNEVYAWDMPD---------MPGEFFALTVDHLF
TH_0621|M.thermoresistible__bu --------MREQGLQVFRELLPGVLPDGDVDFRDGSFGDELLEIGIDNVF
MAV_3552|M.avium_104 MSRSDSAARHQRGVRTFAEVMTFDPPD---------DASPCASGLIDFVF
Mvan_4821|M.vanbaalenii_PYR-1 ----MDPQTYELGRQIRTTVLGADYVQR-AASDADDFSQPLQDLVTEYCW
Mflv_1912|M.gilvum_PYR-GCK ----MDRETYERGRQIREAVLGSEYVER-ATAGADEFSAPLQDLVTEYCW
MSMEG_2604|M.smegmatis_MC2_155 -MTTMRDETHAAGSQVRRAVLGDDHVDR-AVAATTGFTADFQDLITRYAW
* : : :
Mb0794|M.bovis_AF2122/97 GRIWTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDELTIDELR
Rv0771|M.tuberculosis_H37Rv GRIWTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDELTIDELR
TH_0621|M.thermoresistible__bu GRLWTRDGLSRRDRSLVTLGILIALRATDELRFHV-QIARNNGLTEDEIA
MAV_3552|M.avium_104 GEVWSRPGLSRRDRRFVTLACVAAADAQAPLEQHVYAALNSGDLSITEMR
Mvan_4821|M.vanbaalenii_PYR-1 GAVWGRDGLPLKTRSMLNLAMIAVLNRPQELATHIRGALNNG-VTRDEIR
Mflv_1912|M.gilvum_PYR-GCK GAVWGRDGLSRKTRSMLNLAMIATLNRPHELATHIRGALGNG-VTREEIR
MSMEG_2604|M.smegmatis_MC2_155 GEIWTRPGLDRRSRSMITLTAMIARGHHDELAMHVRAARRNG-LSVDEIK
* :* * ** : * : : : . * :: .. :: *:
Mb0794|M.bovis_AF2122/97 ELAVFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPDTKANVAEVLA
Rv0771|M.tuberculosis_H37Rv ELAVFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPDTKANVAEVLA
TH_0621|M.thermoresistible__bu EVIYHATGYAGFPNASTAMKVAKEVLAEEHSRAAD---ADKQSRLGESNP
MAV_3552|M.avium_104 EAVLHFAVYAGWPKASRFNIVVDQQWAR-IAAERGEPTPDPEPLLPLVTA
Mvan_4821|M.vanbaalenii_PYR-1 EIFLQVGIYAGIPAAVDSFRVAKTAFAELEAE------------------
Mflv_1912|M.gilvum_PYR-GCK EIFLHVGVYAGIPAAVDSFRIAKATFAELEGE------------------
MSMEG_2604|M.smegmatis_MC2_155 EVLLQSAIYCGVPEANTAFRIAGAVLAEEAQEPGDER-------------
* * * * . *.
Mb0794|M.bovis_AF2122/97 KESGKSS-------------------------------------------
Rv0771|M.tuberculosis_H37Rv KESGKSS-------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
MAV_3552|M.avium_104 ADPEQRLRGGERSFKDINCLPFAPPRDNPYSGAGILNFVFGEMWLRPGLG
Mvan_4821|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1912|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
Mb0794|M.bovis_AF2122/97 --------------------------------------------------
Rv0771|M.tuberculosis_H37Rv --------------------------------------------------
TH_0621|M.thermoresistible__bu --------------------------------------------------
MAV_3552|M.avium_104 MKERRLITVACVAFQDAEIPIMSHVYAALKSGDVSFREMDEVALQFAAYY
Mvan_4821|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1912|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2604|M.smegmatis_MC2_155 --------------------------------------------------
Mb0794|M.bovis_AF2122/97 -------------------------------
Rv0771|M.tuberculosis_H37Rv -------------------------------
TH_0621|M.thermoresistible__bu -------------------------------
MAV_3552|M.avium_104 GCAKADHLNQALAEQKQRVIAENHSDATPVG
Mvan_4821|M.vanbaalenii_PYR-1 -------------------------------
Mflv_1912|M.gilvum_PYR-GCK -------------------------------
MSMEG_2604|M.smegmatis_MC2_155 -------------------------------