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M. tuberculosis H37Rv Rv0771 (-)

annotation: POSSIBLE 4-CARBOXYMUCONOLACTONE DECARBOXYLASE (CMD)
coordinates: 864140 - 864574
length: 144

MMDELRRTGLDKMNEVYAWDMPDMPGEFFALTVDHLFGRIWTRPGLSMRDRRMAVIAVLTAQGQSDLLEV
QVNAVLHNDELTIDELRELAVFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPDTKANVAEVLAKES
GKSS

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv0771 - - 100% (144) POSSIBLE 4-CARBOXYMUCONOLACTONE DECARBOXYLASE (CMD)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0794 - 8e-79 100.00% (144) 4-carboxymuconolactone decarboxylase
M. gilvum PYR-GCK Mflv_1603 - 1e-47 60.14% (143) carboxymuconolactone decarboxylase
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_1221 - 5e-41 60.50% (119) 4-carboxymuconolactone decarboxylase
M. marinum M MMAR_4925 - 2e-46 61.70% (141) 4-carboxymuconolactone decarboxylase
M. avium 104 MAV_0716 pcaC 2e-45 59.86% (142) hypothetical protein MAV_0716
M. smegmatis MC2 155 MSMEG_5856 pcaC 1e-46 60.00% (145) hypothetical protein MSMEG_5856
M. thermoresistible (build 8) TH_1260 - 1e-45 58.74% (143) POSSIBLE 4-CARBOXYMUCONOLACTONE DECARBOXYLASE (CMD)
M. ulcerans Agy99 MUL_0480 - 1e-45 60.99% (141) 4-carboxymuconolactone decarboxylase
M. vanbaalenii PYR-1 Mvan_5154 - 3e-47 61.43% (140) carboxymuconolactone decarboxylase

CLUSTAL 2.0.9 multiple sequence alignment


Rv0771|M.tuberculosis_H37Rv         ---------MMDELRRTGLDKMNEVYAWDMPDMPG-EFFALTVDHLFGRI
Mb0794|M.bovis_AF2122/97            ---------MMDELRRTGLDKMNEVYAWDMPDMPG-EFFALTVDHLFGRI
Mflv_1603|M.gilvum_PYR-GCK          --------MTMDELRRKGLEKMNEVYGWEMPNIEGDPYFDLTVDHLFGTI
MSMEG_5856|M.smegmatis_MC2_155      ----------MDELRRKGLEKMNEVYGWEMPNIEGDPYFDLTVDHLFGTI
TH_1260|M.thermoresistible__bu      ----------MDELRRRGLEKMNEVYGWEMPNIEGDPYFDLTVDHLFGTI
Mvan_5154|M.vanbaalenii_PYR-1       --------MSTDELRRKGLEKMNEVYGWEMPDVQGDPYYDLTVEHLFGSI
MMAR_4925|M.marinum_M               ----------MDELRRKGLDKMNEVYGWEMPNIEGDAYFDLTVDHLFGTI
MUL_0480|M.ulcerans_Agy99           ----------MDELRRKGLDKMNEVYGWEMPNIEGDAYFDLTVDHLFGTI
MAV_0716|M.avium_104                ---------MMDERRRKGLEKMNEVYGWEMPNVEGDAYFDLTVDHLFGSI
MAB_1221|M.abscessus_ATCC_1997      MVCHTRKGQVMDELRRQGLDKMKEVYGWDMPDIPG-DYFKYTIDHLFGTI
                                               ** ** **:**:***.*:**:: *  ::  *::**** *

Rv0771|M.tuberculosis_H37Rv         WTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDELTIDELRELA
Mb0794|M.bovis_AF2122/97            WTRPGLSMRDRRMAVIAVLTAQGQSDLLEVQVNAVLHNDELTIDELRELA
Mflv_1603|M.gilvum_PYR-GCK          WTREGLSMRDKRLLTLAAVTAVGNSDLAEIQVNAALHNEEFTAEELKEVA
MSMEG_5856|M.smegmatis_MC2_155      WTREGLSMREKRLLTLASVTAVGNSDLAEIQVNAALHNEEFTVDELKEVA
TH_1260|M.thermoresistible__bu      WTRPGLSMRDKRIMTLTAVTAVGNSDLAEIQANAALANGELTEDELKEMA
Mvan_5154|M.vanbaalenii_PYR-1       WTRPGLSMRDKRMMTLTVVTALGNSDLAEIQVNAALHNEELTEHELKEMA
MMAR_4925|M.marinum_M               WTRPGLSMRDRRLMTLTAVTAIGNRDLAEIQINAALLNGELTEAELKEMA
MUL_0480|M.ulcerans_Agy99           WTRPGLSMRDRRLMTLTAVTAIGNRDLAEIQINAAPLNGELTEAELKEMA
MAV_0716|M.avium_104                WTRPGLSMRDKRIMTLTAVTAIGNRDLAEIQINAALLNGELTETELKEMA
MAB_1221|M.abscessus_ATCC_1997      WTRPELSMRDRRLLLLGAVSALGLDEILEIQTSAALKNGELTEAELREVA
                                    ***  ****::*:  :  ::* *  :: *:* .*.  * *:*  **:*:*

Rv0771|M.tuberculosis_H37Rv         VFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPD----TKANVAEVL
Mb0794|M.bovis_AF2122/97            VFITHYVGFPLGSRLNSAIERVAAKRKQAAENGSLPD----TKANVAEVL
Mflv_1603|M.gilvum_PYR-GCK          LFLTHYLGFPLGSKLDGAVSKVIRNRKKAADKGSGED----RKANVNAAV
MSMEG_5856|M.smegmatis_MC2_155      VFLTHYLGFPLGSKLDGAVSKVARNRKKAAEKGEREDTAEKRRANVNAAV
TH_1260|M.thermoresistible__bu      VFLTHYLGFPLGSKLDGAVSKVIKNRRKAAAEGKGED----RKANVDAAV
Mvan_5154|M.vanbaalenii_PYR-1       VFLTHYLGFPLGSKLDGVVSKVAKQRKKAAERGEGEN----KKANVNAAV
MMAR_4925|M.marinum_M               VFLTHYLGFPLGSGLNGAVDTVVARRKKAAAKGAGED----KKGNVDDAL
MUL_0480|M.ulcerans_Agy99           VFLTHYLGFPLGSGLNGAVDTVVARRKKAAAKGAGED----KKGNVDDAL
MAV_0716|M.avium_104                VFLTHYLGFPLGSALNGAVDAVVAKRRKAAAKGAGED----KKANVDAAL
MAB_1221|M.abscessus_ATCC_1997      IFITHYVGWPLGQRVNKHVEMAVAKQNEARRTKESSD---------D---
                                    :*:***:*:***. ::  :. .  .:.:*       :             

Rv0771|M.tuberculosis_H37Rv         AKESGKSS------
Mb0794|M.bovis_AF2122/97            AKESGKSS------
Mflv_1603|M.gilvum_PYR-GCK          KMHSGKTLDDE---
MSMEG_5856|M.smegmatis_MC2_155      KMHSGSKLDDK---
TH_1260|M.thermoresistible__bu      RMHSGETIHDQHDQ
Mvan_5154|M.vanbaalenii_PYR-1       QMHSGGKVHDDHDQ
MMAR_4925|M.marinum_M               KMHSGGKPD-----
MUL_0480|M.ulcerans_Agy99           KMHSGSKPD-----
MAV_0716|M.avium_104                KMHSGGERG-----
MAB_1221|M.abscessus_ATCC_1997      --------------

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv0771	-	-	100% (144)	POSSIBLE 4-CARBOXYMUCONOLACTONE DECARBOXYLASE (CMD)