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MSVTTAGAAARKHAEPKSSNKIQGGLLDPNMLWKSLPSALRKLDPRTMWRNPVMFIVEIGAVWSTILAFL EPSWFAWLIVVWLWLTVLFANLAEAVAEGRGKAQAESLRKTKTATPARRLTGWAPGTPGREEAVAAALLQ PGDIVVVEAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTVLSDRIVVKITQKPGE SFIDRMIALVEGANRQKTPNEIALNILLASLTIIFVFAVTTLQPLAIYSKMNNPGVPDSLALNGNGITGI VMVSLLVCLIPTTIGALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITLGNRQASEFV PLTGVTPEALADAAQLSSLADETPEGRSIVVFAKQEYGLRARTPGELAHAAWIEFSATTRMSGVDVDGHR LRKGATSAVAEWVRSEGGTVPTELGDIVDGISAAGGTPLAVGEVREGKAAVLGVIHLKDVVKQGMRERFD EMRRMGIRTVMITGDNPMTAKAIADEAGVDDFLAEATPEDKMALIKKEQAGGRLVAMTGDGTNDAPALAQ ADVGVAMNSGTSAAKEAGNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPALFVGL FPGLDLLNVMRLHSPQSAILSAVIFNAVVIIALIPLSLRGVRYTPSSASKLLSRNLYIFGLGGIIAPFVG IKAIDLIIQLFPGM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4760 | - | - | 100% (714) | potassium-transporting ATPase subunit B |
| M. vanbaalenii PYR-1 | Mvan_4449 | - | 3e-51 | 29.01% (586) | heavy metal translocating P-type ATPase |
| M. vanbaalenii PYR-1 | Mvan_5853 | - | 2e-47 | 30.02% (473) | heavy metal translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1059 | kdpB | 0.0 | 69.18% (717) | potassium-transporting ATPase subunit B |
| M. gilvum PYR-GCK | Mflv_2849 | - | 6e-53 | 30.05% (589) | heavy metal translocating P-type ATPase |
| M. tuberculosis H37Rv | Rv1030 | kdpB | 0.0 | 69.18% (717) | potassium-transporting ATPase subunit B |
| M. leprae Br4923 | MLBr_00747 | ctpC | 9e-46 | 28.48% (597) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_3253c | - | 0.0 | 67.09% (705) | potassium-transporting ATPase B chain |
| M. marinum M | MMAR_0632 | kdpB | 0.0 | 86.21% (696) | high-affinity K+ transport system, ATPase chain B, KdpB |
| M. avium 104 | MAV_1172 | kdpB | 0.0 | 85.87% (715) | potassium-transporting ATPase subunit B |
| M. smegmatis MC2 155 | MSMEG_5393 | kdpB | 0.0 | 85.67% (719) | potassium-transporting ATPase subunit B |
| M. thermoresistible (build 8) | TH_4361 | - | 1e-49 | 29.93% (548) | PUTATIVE heavy metal translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_0423 | ctpV | 2e-51 | 28.65% (576) | metal cation transporter p-type ATPase, CtpV |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1059|M.bovis_AF2122/97 --------------------------------------------------
Rv1030|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1172|M.avium_104 --------------------------------------------------
MMAR_0632|M.marinum_M --------------------------------------------------
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2849|M.gilvum_PYR-GCK ----------------MTTSIPVSGPSIELRIGGMTCASCANRIERKLNK
TH_4361|M.thermoresistible__bu ----------------MNTGG---MNTVTLTVGGMTCASCAARVEKRLNR
MUL_0423|M.ulcerans_Agy99 --------------------------MRVHANGFAIDATRAAAIEESVGR
MLBr_00747|M.leprae_Br4923 MTLAMAEQIATADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAK
Mb1059|M.bovis_AF2122/97 --------------------------------------------------
Rv1030|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1172|M.avium_104 --------------------------------------------------
MMAR_0632|M.marinum_M --------------------------------------------------
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2849|M.gilvum_PYR-GCK IDGVAATVNYATEKATVTV--PDGYDPALLIAEVQNAGYS--AALPTPEK
TH_4361|M.thermoresistible__bu IDGVVATVNFATEQATVRY--PDHVDPADLIAAIEATGYT--ASLPAPQR
MUL_0423|M.ulcerans_Agy99 VGGVRAVRAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAA
MLBr_00747|M.leprae_Br4923 CNGVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAHVAAELIPTRAP
Mb1059|M.bovis_AF2122/97 --------------------------------------------------
Rv1030|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1172|M.avium_104 --------------------------------------------------
MMAR_0632|M.marinum_M --------------------------------------------------
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2849|M.gilvum_PYR-GCK -------PALTG----------------ETGETEDPDLVSLRHRLTGS--
TH_4361|M.thermoresistible__bu DTGGAPAGAATG----------------AAGDDHDAEAERWRRRLTIS--
MUL_0423|M.ulcerans_Agy99 RVAGIADGGVVGRVIGGLARALLGMRTDDNDDDPPPEIARLRAALDRIGY
MLBr_00747|M.leprae_Br4923 ------------------------------HSSDIRNIEVLRMAIGAA--
Mb1059|M.bovis_AF2122/97 -----------------------------MMIARMETSATAAAATSAPRL
Rv1030|M.tuberculosis_H37Rv -----------------------------MMIARMETSATAAAATSAPRL
Mvan_4760|M.vanbaalenii_PYR-1 ------------------------------MSVTTAGAAARKHAEPKS-S
MAV_1172|M.avium_104 ------------------------------MTVTAIDPAEQAHPAPSAGT
MMAR_0632|M.marinum_M ------------------------------MSTTVG--------------
MSMEG_5393|M.smegmatis_MC2_155 ------------------------------MPVHTAQQAVSNHANPKP-T
MAB_3253c|M.abscessus_ATCC_199 ------------------------------MSKSKN--------------
Mflv_2849|M.gilvum_PYR-GCK --------------------------VLLSVPVIAMAMIPVLQFTYWQWA
TH_4361|M.thermoresistible__bu --------------------------AALSIPVVVLSMIPALQFTHWQWL
MUL_0423|M.ulcerans_Agy99 SPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLLASGLTMFFGAYPWA
MLBr_00747|M.leprae_Br4923 --------------------------------ALTLLGVRRYVFARPLLL
Mb1059|M.bovis_AF2122/97 RLAKRSLFDPMIVRSALPQSLRKLAPRVQARNPVMLVVLVGAVITTLAFL
Rv1030|M.tuberculosis_H37Rv RLAKRSLFDPMIVRSALPQSLRKLAPRVQARNPVMLVVLVGAVITTLAFL
Mvan_4760|M.vanbaalenii_PYR-1 NKIQGGLLDPNMLWKSLPSALRKLDPRTMWRNPVMFIVEIGAVWSTILAF
MAV_1172|M.avium_104 KRVQGGLLDPKMLWRSTPDALRKLDPRTLWRNPVMFIVEIGAAWSTVLAI
MMAR_0632|M.marinum_M ----SGLLDPTMLWKSLPAAVRKLDPRTLWRNPVMFIVELGAVWSTLLAV
MSMEG_5393|M.smegmatis_MC2_155 SQVQGGLLDPKMLWRSLPDALRKLNPRTLWRNPVMFIVEVGAVWSTILAG
MAB_3253c|M.abscessus_ATCC_199 AVVTTGVFDPAQLIKALPLAVRKLDPRHMARNPVMFVVTVGSVATTVLAV
Mflv_2849|M.gilvum_PYR-GCK ---SLVLAAPVIVWAAWPFHRAAWANLRHATATMDTLISLGTLSAFLWSL
TH_4361|M.thermoresistible__bu ---ALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSL
MUL_0423|M.ulcerans_Agy99 GWLAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLGTLTAFIYST
MLBr_00747|M.leprae_Br4923 PTTSRLVASGVTIFTGYPFLRGALR---FGKTGTDALVSAATIASLILRE
. . * :: . : :
Mb1059|M.bovis_AF2122/97 RDLASSTAQ-----------------ENVFNGLVAAFLWFTVLFANFAEA
Rv1030|M.tuberculosis_H37Rv RDLASSTAQ-----------------ENVFNGLVAAFLWFTVLFANFAEA
Mvan_4760|M.vanbaalenii_PYR-1 LEPS------------------------WFAWLIVVWLWLTVLFANLAEA
MAV_1172|M.avium_104 VGPT------------------------WFAWLTVIWLWLTVLFANLAEA
MMAR_0632|M.marinum_M VDPS------------------------WFAGLIVAWLWLTVIFANLAEA
MSMEG_5393|M.smegmatis_MC2_155 VNPT------------------------WFGWLIVAWLWLTVVFANLAEA
MAB_3253c|M.abscessus_ATCC_199 LHPS------------------------IFAWAITAWLWFTVVFANLAEA
Mflv_2849|M.gilvum_PYR-GCK YALFFGTAGTPGMKHPFELTLAPSHGAANIYLEVAAGVTTFILAGRYFEK
TH_4361|M.thermoresistible__bu WALFFTAAGMPGMTMTFTL-LPADTGEPHIYLEVAAAVTTFIIAGRYFEA
MUL_0423|M.ulcerans_Agy99 YQLFAGGP---------------------LFFDTAALIIAFVVLGRYFEA
MLBr_00747|M.leprae_Br4923 N-------------------------------VVALAVLWLLNIGEYLQD
. : : .. :
Mb1059|M.bovis_AF2122/97 MAEGRGKAQAAALRKVRSETMANRRT-----AAGNIESVPSSRLDLDDVV
Rv1030|M.tuberculosis_H37Rv MAEGRGKAQAAALRKVRSETMANRRT-----AAGNIESVPSSRLDLDDVV
Mvan_4760|M.vanbaalenii_PYR-1 VAEGRGKAQAESLRKTKTATPARRLTGWAPGTPGREEAVAAALLQPGDIV
MAV_1172|M.avium_104 VAEGRGKAQAETLRRAKTQTMARRLRDWAPGSTGIEEAVAATALQQGDIV
MMAR_0632|M.marinum_M VAEGRGKAQADTLRKTKADTMARLLT-----ATGAEEQVTAALLQPGDIV
MSMEG_5393|M.smegmatis_MC2_155 VAEGRGKAQAESLRKTKADTMARRLT-----ESGAEEAVPAPQLRQGDIV
MAB_3253c|M.abscessus_ATCC_199 VAEGRGKAQAASLREVKRDTVARRLVG-DGNGNENEEEVPGSALRPGDRV
Mflv_2849|M.gilvum_PYR-GCK RSKRQAGAALRALLEMGAKEVSVLRD-------GVESKIAVEDLVVGDEF
TH_4361|M.thermoresistible__bu RAKRQSGAALRALLDMGANDVAVLRD-------GAEKRVPIGELHVGDVF
MUL_0423|M.ulcerans_Agy99 TAHGKTREAISKLLDMGAKETRLIVD-------GEEHLVPVDRVQVGDLV
MLBr_00747|M.leprae_Br4923 LTLRRTRRAISALLSGTQDTAWIRLTD--GPQAGTEIQVPIGTVQIGDEV
: : * :. : .* .
Mb1059|M.bovis_AF2122/97 EVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGGTVV
Rv1030|M.tuberculosis_H37Rv EVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGGTVV
Mvan_4760|M.vanbaalenii_PYR-1 VVEAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
MAV_1172|M.avium_104 VVEAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
MMAR_0632|M.marinum_M VVDAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
MSMEG_5393|M.smegmatis_MC2_155 VVEAGQTIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
MAB_3253c|M.abscessus_ATCC_199 VVEAGQVIPGDGDVVEGIATVDESAITGESAPVVRESGGDRCAVTGGTTV
Mflv_2849|M.gilvum_PYR-GCK VVRPGEKIATDGVVASGTSAVDASMLTGESVPVEVGPG---DTVVGATVN
TH_4361|M.thermoresistible__bu VVRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPG---DQVVGATVN
MUL_0423|M.ulcerans_Agy99 RVRPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVG---DWVAGATVN
MLBr_00747|M.leprae_Br4923 VVHEHVAIPVDGEVIDGEAVVNQSAITGENLPVSVMAG---SHVHAGSVV
* *. ** : * : *: * :***. ** * * ..:.
Mb1059|M.bovis_AF2122/97 LSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALN-ILLAGLTII
Rv1030|M.tuberculosis_H37Rv LSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALN-ILLAGLTII
Mvan_4760|M.vanbaalenii_PYR-1 LSDRIVVKITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLASLTII
MAV_1172|M.avium_104 LSDRIVVQITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLAALTII
MMAR_0632|M.marinum_M LSDRILVKITQKPGESFIDKMIALVEGADRQKTPNEIALN-ILLASLTII
MSMEG_5393|M.smegmatis_MC2_155 LSDRIVVRITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLAALTII
MAB_3253c|M.abscessus_ATCC_199 LSDRIVVQITAAPGESFVDRMIALVEGASRQKTPNEIALN-ILLASLTII
Mflv_2849|M.gilvum_PYR-GCK AGGRLVVRAARVGSDTQLAQMAQLVENAQTGKAQVQRLADRISGVFVPIV
TH_4361|M.thermoresistible__bu VGGHLQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIV
MUL_0423|M.ulcerans_Agy99 TDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFVPVV
MLBr_00747|M.leprae_Br4923 VRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTS
. : *: : .: : :: * * :: : : . :.
Mb1059|M.bovis_AF2122/97 FLLAVVTLQPFAIYS--------------GGGQRVVVLVALLVCLIPTTI
Rv1030|M.tuberculosis_H37Rv FLLAVVTLQPFAIYS--------------GGGQRVVVLVALLVCLIPTTI
Mvan_4760|M.vanbaalenii_PYR-1 FVFAVTTLQPLAIYSKMNNPGVPDSLALNGNGITGIVMVSLLVCLIPTTI
MAV_1172|M.avium_104 FVFAVATLQPLAIYSKVNNPGVPDTQALNTSGVTGIVMVSLLVCLIPTTI
MMAR_0632|M.marinum_M FVFTVVTLQPLAIYSKANNPGVADTVALNANGISGIVMVSLLVCLIPTTI
MSMEG_5393|M.smegmatis_MC2_155 FVFAVATLQPLAIYAKANNPGVPDSLALTGNGISGIVMVALLVCLIPTTI
MAB_3253c|M.abscessus_ATCC_199 FLLAVVALGPMGNYG--------------GEQQDPIKLIALLVCLIPTTI
Mflv_2849|M.gilvum_PYR-GCK LAIAVITLGAWLG-AG------------FPVAAAFTAAVAVLVIACPCAL
TH_4361|M.thermoresistible__bu IALSALTLAGWLLLTD------------APVSAAFTAAVAVLIIACPCAL
MUL_0423|M.ulcerans_Agy99 VRIAAATFAGWTLLAA------------NPVAG-MTAAVSVLIIACPYAL
MLBr_00747|M.leprae_Br4923 FVVSAITLA---------------------ITKDVRRTMTVLLIACPCAV
. .:. :: :::*: * ::
Mb1059|M.bovis_AF2122/97 GALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITLGNR
Rv1030|M.tuberculosis_H37Rv GALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITLGNR
Mvan_4760|M.vanbaalenii_PYR-1 GALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITLGNR
MAV_1172|M.avium_104 GALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITLGNR
MMAR_0632|M.marinum_M GALLSAIGIAGMDRLVQRNILAMSGRAVEAAGDVNTLLLDKTGTITLGNR
MSMEG_5393|M.smegmatis_MC2_155 GALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITLGNR
MAB_3253c|M.abscessus_ATCC_199 GALMSAIGIAGMDRLVQHNVLAKSGRAVEAAGDIDTLLMDKTGTITFGNR
Mflv_2849|M.gilvum_PYR-GCK GLATPTALLVGTGRGAQMGVLIKGPEVLESTRKVDTVVLDKTGTVTTGKM
TH_4361|M.thermoresistible__bu GLATPTALLVGTGRGAQLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQM
MUL_0423|M.ulcerans_Agy99 GLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTRAQM
MLBr_00747|M.leprae_Br4923 GLATPTAISAAIGNGARRGILIKGGSHLEQAGRVDAILFDKTGTLTVGRP
* .: .. .. . .:* . :* : ::::::*****:* ..
Mb1059|M.bovis_AF2122/97 QATEFVPI-NGVSAEAVADAAQLSSLADETPEGRSIVVLAKDEFGLRARD
Rv1030|M.tuberculosis_H37Rv QATEFVPI-NGVSAEAVADAAQLSSLADETPEGRSIVVLAKDEFGLRARD
Mvan_4760|M.vanbaalenii_PYR-1 QASEFVPL-TGVTPEALADAAQLSSLADETPEGRSIVVFAKQEYGLRART
MAV_1172|M.avium_104 QAAAFIPL-AGVPPEELADAAQLSSLADETPEGRSVVVFAKQHFGLRART
MMAR_0632|M.marinum_M QAGAFVHL-PGVSEAELADAAQLSSLADETPEGRSIVVYAKQQYGLRART
MSMEG_5393|M.smegmatis_MC2_155 QAAAFVPL-TGVTPESLADAAQLSSLADETPEGRSIVVFAKREFGLRART
MAB_3253c|M.abscessus_ATCC_199 QATEFLVA-PGIPHETLAAAARASSLADETPEGRSIVELA-------AGT
Mflv_2849|M.gilvum_PYR-GCK TLVDVVTA-PGTDRGNLLRLAGALENASEHPIAQAVATAATE--------
TH_4361|M.thermoresistible__bu SVTSVHVA-DGLSETELLRLAGAVEHASEHPIARAVATHAAQ--------
MUL_0423|M.ulcerans_Agy99 ELTDVIAG-KRRQPDVVLRIAAAVESGSEHPIGAAIVAGARE--------
MLBr_00747|M.leprae_Br4923 VVTNIVAMHKDWSPEQVLAYAASSEIHSRHPLAEAVIRSTEE--------
. : * . .. * . :: :
Mb1059|M.bovis_AF2122/97 EGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAAAAVMKWVRDHGGH
Rv1030|M.tuberculosis_H37Rv EGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAAAAVMKWVRDHGGH
Mvan_4760|M.vanbaalenii_PYR-1 PGELAHAAWIEFSATTRMSGVDVDGHR----LRKGATSAVAEWVRSEGGT
MAV_1172|M.avium_104 PGELSQAQWVAFSATTRMSGVDLDGHS----LRKGAASSVAEWVRSQRGS
MMAR_0632|M.marinum_M PGELAHAQWIEFSATTRMSGVNVDGHL----LRKGAANAVADWVRTQGGE
MSMEG_5393|M.smegmatis_MC2_155 PGELAEAHWIEFSATTRMSGVNLGEHR----LRKGAAAAVVDWVRGEGGT
MAB_3253c|M.abscessus_ATCC_199 IEESVAGEFVAFTASTRMSGLDTVEGR---QIRKGASDAVFTWVASLSGV
Mflv_2849|M.gilvum_PYR-GCK ----ELGTLPTPEDFANVEGKGVQGIVDGHAVVVGRESLLADWSQH----
TH_4361|M.thermoresistible__bu ----TVPPLPEVSDFENHGGNGVSGRVDGHDVRVGR---LAWLGLS----
MUL_0423|M.ulcerans_Agy99 ----RELEVPPATEFTNLAGHGVRGEVGGKSVLVGRRKLVDEQHLR----
MLBr_00747|M.leprae_Br4923 ----RHISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLCAEKVK----
* . : * :
Mb1059|M.bovis_AF2122/97 -----PTEEVGAIVDGISSGGGTPLVVAEWTDNS----SARAIGVVHLKD
Rv1030|M.tuberculosis_H37Rv -----PTEEVGAIVDGISSGGGTPLVVAEWTDNS----SARAIGVVHLKD
Mvan_4760|M.vanbaalenii_PYR-1 -----VPTELGDIVDGISAAGGTPLAVGEVREG-----KAAVLGVIHLKD
MAV_1172|M.avium_104 -----VPHQLGEIVDGISAGGGTPLVVGESVDG-----RARVLGVIHLKD
MMAR_0632|M.marinum_M -----VPPELKATVEAISAGGGTPLAVAQVLDG-----TASVLGVIHLKD
MSMEG_5393|M.smegmatis_MC2_155 -----VPVELFDVVDAISHAGGTPLVVGHVITDDTDPKRAEVLGVIHLKD
MAB_3253c|M.abscessus_ATCC_199 QEDDPVVVAVRKIADQVASEGGTPLVVADHDST-----ETRLLGVIRLSD
Mflv_2849|M.gilvum_PYR-GCK -----LSPELARAKASAEAQGKTAVAVGW---------DGEARGVLVVAD
TH_4361|M.thermoresistible__bu -----AGDRLRNAAAQAEAAGHTPVWVAV---------DGRIAGVIVVSD
MUL_0423|M.ulcerans_Agy99 -----LPEQLAAAAADLEERGRTAVYVGQ---------DGQVVGVLAVAD
MLBr_00747|M.leprae_Br4923 -----VSKTASEWVDKLRHQTETPLLFAV---------DGTLVGLISLRD
*.: .. *:: : *
Mb1059|M.bovis_AF2122/97 IVKVGIRERFDEMRRMSIR-TVMITGDNPATAKAIAQEAGVDDFLAEATP
Rv1030|M.tuberculosis_H37Rv IVKVGIRERFDEMRRMSIR-TVMITGDNPATAKAIAQEAGVDDFLAEATP
Mvan_4760|M.vanbaalenii_PYR-1 VVKQGMRERFDEMRRMGIR-TVMITGDNPMTAKAIADEAGVDDFLAEATP
MAV_1172|M.avium_104 VVKQGMRERFDEMRRMGIR-TVMITGDNPLTAKAIADEAGVDDFLAEATP
MMAR_0632|M.marinum_M VVKHGMRERFDEMRRMGIR-TVMITGDNPLTAKAIAEEAGVDDFLAEATP
MSMEG_5393|M.smegmatis_MC2_155 VVKQGMKQRFDEMRRMGIR-TVMITGDNPLTAKAIADEAGVDDFLAEATP
MAB_3253c|M.abscessus_ATCC_199 VVKPGMAERFAQMRAMGIR-TVMVTGDNPLTAKQIAAEAGVDDFVAEATP
Mflv_2849|M.gilvum_PYR-GCK TVKPTSAQAISQMREIGLT-PVLLTGDNEAVARQIAAEVGIDTVIAEVMP
TH_4361|M.thermoresistible__bu TVKDHAAEAIAELRALGAT-PVLLTGDNDRAARTVAAQVGIDDVIAGVLP
MUL_0423|M.ulcerans_Agy99 TVKDDAADVVSQLHAMGLQ-VALITGDNARTAAAIAAQVGIDRVLAEVLP
MLBr_00747|M.leprae_Br4923 EVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRAEVMP
*: : . ::: . .::***: * :* : *:* * . *
Mb1059|M.bovis_AF2122/97 EDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TQAAREA
Rv1030|M.tuberculosis_H37Rv EDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TQAAREA
Mvan_4760|M.vanbaalenii_PYR-1 EDKMALIKKEQAGGRLVAMTGDGTNDAPALAQADVGVAMNSG-TSAAKEA
MAV_1172|M.avium_104 EDKLQLIKREQAGGKLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
MMAR_0632|M.marinum_M EDKLALIKREQGGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
MSMEG_5393|M.smegmatis_MC2_155 EDKLALIKQEQAGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
MAB_3253c|M.abscessus_ATCC_199 EDKLELLRKEQQAGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
Mflv_2849|M.gilvum_PYR-GCK KDKVDVIVRLQAEGKTVAMVGDGVNDAPALAQADLGLAMGTG-TDVAIEA
TH_4361|M.thermoresistible__bu AEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTG-TDVAIEA
MUL_0423|M.ulcerans_Agy99 ADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGIAIGTG-TDVAIEA
MLBr_00747|M.leprae_Br4923 EDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDVAVET
:*: : * * *.* ***.***.**. **:*:*:. . *..* *:
Mb1059|M.bovis_AF2122/97 GNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAMF
Rv1030|M.tuberculosis_H37Rv GNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAMF
Mvan_4760|M.vanbaalenii_PYR-1 GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPALF
MAV_1172|M.avium_104 GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPAMF
MMAR_0632|M.marinum_M GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPALF
MSMEG_5393|M.smegmatis_MC2_155 GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSISNDIAKYFAIIPALF
MAB_3253c|M.abscessus_ATCC_199 GNMVDLDSDPTKLIDVVAIGKQLLITRGALTTFSLANDLAKYFAILPALF
Mflv_2849|M.gilvum_PYR-GCK SDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFVYNVAAIPVAALGML
TH_4361|M.thermoresistible__bu SDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLAAAGLL
MUL_0423|M.ulcerans_Agy99 SDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFGYNTAAIPLAALGVL
MLBr_00747|M.leprae_Br4923 ADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGAGGAL
.::. . . :. : . :: : * . :
Mb1059|M.bovis_AF2122/97 VGLYPVLDKLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFRAES
Rv1030|M.tuberculosis_H37Rv VGLYPVLDKLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFRAES
Mvan_4760|M.vanbaalenii_PYR-1 VGLFPGLDLLNVMRLHSPQSAILSAVIFNAVVIIALIPLSLRGVRYTPSS
MAV_1172|M.avium_104 VALFPGLDLINVMRLHSPQSAILSAVIFNAIIIVLLIPLSLRGVRYTPSS
MMAR_0632|M.marinum_M VGLFPGLDLLNIMRLHSPQSAILSAVIFNALVIVALIPLALRGVRYTPSS
MSMEG_5393|M.smegmatis_MC2_155 VGLFPGLDLLNIMRLHSPQSAILSAVIFNAIVIVALIPLALKGVRYTPSS
MAB_3253c|M.abscessus_ATCC_199 SGIYPQLGALNIMRLATPQSAILSAVVFNALVIIALVPLALKGVRYRPVG
Mflv_2849|M.gilvum_PYR-GCK N--------------------PMLAGAAMAFSSVFVVGNSLRLRGFTSTS
TH_4361|M.thermoresistible__bu N--------------------PLIAGAAMAFSSVFVVSNSLRLRRFTPSR
MUL_0423|M.ulcerans_Agy99 N--------------------PVVAGAAMGLSSVSVVTNSLRLRRFGRDV
MLBr_00747|M.leprae_Br4923 S--------------------PVLAAVLHNASSVAVVANSSRLIRYRLD-
: * : :: : : :
Mb1059|M.bovis_AF2122/97 ASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVAL-GVS
Rv1030|M.tuberculosis_H37Rv ASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVAL-GVS
Mvan_4760|M.vanbaalenii_PYR-1 ASKLLSRNLYIFGLGGIIAPFVGIKAIDLIIQLFPGM-
MAV_1172|M.avium_104 ASKLLSRNLYIYGLGGIVAPFIGIKAIDLIVQFVPGMS
MMAR_0632|M.marinum_M ASKLLSRNLSIYGLGGIVAPFIGIKLIDLIIQFLPGMS
MSMEG_5393|M.smegmatis_MC2_155 AAKLLSRNLYIYGLGGIIAPFLGIKLIDLVVQLLPGMS
MAB_3253c|M.abscessus_ATCC_199 AGELLRRNLLIYGLGGVIVPFVGIWLIDLVVRFIPGIG
Mflv_2849|M.gilvum_PYR-GCK TSSAPTH-------------------------------
TH_4361|M.thermoresistible__bu --------------------------------------
MUL_0423|M.ulcerans_Agy99 --------------------------------------
MLBr_00747|M.leprae_Br4923 --------------------------------------