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VMIARMETSATAAAATSAPRLRLAKRSLFDPMIVRSALPQSLRKLAPRVQARNPVMLVVLVGAVITTLAF LRDLASSTAQENVFNGLVAAFLWFTVLFANFAEAMAEGRGKAQAAALRKVRSETMANRRTAAGNIESVPS SRLDLDDVVEVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGGTVVLSDRIVVRITA KQGQTFIDRMIALVEGAARQQTPNEIALNILLAGLTIIFLLAVVTLQPFAIYSGGGQRVVVLVALLVCLI PTTIGALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITLGNRQATEFVPINGVSAEAV ADAAQLSSLADETPEGRSIVVLAKDEFGLRARDEGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAA AAVMKWVRDHGGHPTEEVGAIVDGISSGGGTPLVVAEWTDNSSARAIGVVHLKDIVKVGIRERFDEMRRM SIRTVMITGDNPATAKAIAQEAGVDDFLAEATPEDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGV AMNTGTQAAREAGNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAMFVGLYPVLD KLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFRAESASAMLRRNLLIYGLGGLVVPFIGIKLVD LVIVALGVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1030 | kdpB | - | 100% (709) | potassium-transporting ATPase subunit B |
| M. tuberculosis H37Rv | Rv0969 | ctpV | 1e-52 | 29.52% (542) | metal cation transporter P-type ATPase CtpV |
| M. tuberculosis H37Rv | Rv3270 | ctpC | 1e-44 | 28.57% (539) | metal cation-transporting P-type ATPase C CtpC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1059 | kdpB | 0.0 | 100.00% (709) | potassium-transporting ATPase subunit B |
| M. gilvum PYR-GCK | Mflv_2244 | - | 4e-54 | 29.55% (599) | heavy metal translocating P-type ATPase |
| M. leprae Br4923 | MLBr_00747 | ctpC | 1e-47 | 29.04% (606) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_3253c | - | 0.0 | 65.99% (685) | potassium-transporting ATPase B chain |
| M. marinum M | MMAR_0632 | kdpB | 0.0 | 71.01% (690) | high-affinity K+ transport system, ATPase chain B, KdpB |
| M. avium 104 | MAV_1172 | kdpB | 0.0 | 67.78% (720) | potassium-transporting ATPase subunit B |
| M. smegmatis MC2 155 | MSMEG_5393 | kdpB | 0.0 | 70.59% (697) | potassium-transporting ATPase subunit B |
| M. thermoresistible (build 8) | TH_4361 | - | 4e-48 | 28.60% (542) | PUTATIVE heavy metal translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_0423 | ctpV | 7e-55 | 29.93% (538) | metal cation transporter p-type ATPase, CtpV |
| M. vanbaalenii PYR-1 | Mvan_4760 | - | 0.0 | 69.18% (717) | potassium-transporting ATPase subunit B |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1030|M.tuberculosis_H37Rv ----------------------------------------------MMIA
Mb1059|M.bovis_AF2122/97 ----------------------------------------------MMIA
MAV_1172|M.avium_104 -----------------------------------------------MTV
Mvan_4760|M.vanbaalenii_PYR-1 -----------------------------------------------MSV
MMAR_0632|M.marinum_M -----------------------------------------------MST
MSMEG_5393|M.smegmatis_MC2_155 -----------------------------------------------MPV
MAB_3253c|M.abscessus_ATCC_199 -----------------------------------------------MSK
Mflv_2244|M.gilvum_PYR-GCK ------------------------MNTLELSIGGMTCASCAARVEKKLNK
TH_4361|M.thermoresistible__bu -------------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNR
MUL_0423|M.ulcerans_Agy99 --------------------------MRVHANGFAIDATRAAAIEESVGR
MLBr_00747|M.leprae_Br4923 MTLAMAEQIATADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAK
:
Rv1030|M.tuberculosis_H37Rv RMETSATAAAATSAPRLRLAKRSLFDPMIVRSALPQSLRKLAPRVQARN-
Mb1059|M.bovis_AF2122/97 RMETSATAAAATSAPRLRLAKRSLFDPMIVRSALPQSLRKLAPRVQARN-
MAV_1172|M.avium_104 TAIDPAEQAHPAPSAGTKRVQGGLLDPKMLWRSTPDALRKLDPRTLWRN-
Mvan_4760|M.vanbaalenii_PYR-1 TTAGAAARKHAEPKS-SNKIQGGLLDPNMLWKSLPSALRKLDPRTMWRN-
MMAR_0632|M.marinum_M TVG------------------SGLLDPTMLWKSLPAAVRKLDPRTLWRN-
MSMEG_5393|M.smegmatis_MC2_155 HTAQQAVSNHANPKP-TSQVQGGLLDPKMLWRSLPDALRKLNPRTLWRN-
MAB_3253c|M.abscessus_ATCC_199 SKN--------------AVVTTGVFDPAQLIKALPLAVRKLDPRHMARN-
Mflv_2244|M.gilvum_PYR-GCK LDGVTATVNYATEKARVEFG--DNVSTDQLVSAVESAGYQ--AALPEPPN
TH_4361|M.thermoresistible__bu IDGVVATVNFATEQATVRYP--DHVDPADLIAAIEATGYT--ASLPAPQR
MUL_0423|M.ulcerans_Agy99 VGGVRAVRAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAA
MLBr_00747|M.leprae_Br4923 CNGVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAHVAAELIPTRAP
. : : :
Rv1030|M.tuberculosis_H37Rv --------------------------------------------------
Mb1059|M.bovis_AF2122/97 --------------------------------------------------
MAV_1172|M.avium_104 --------------------------------------------------
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0632|M.marinum_M --------------------------------------------------
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2244|M.gilvum_PYR-GCK PPDVEPAD------------------------------------------
TH_4361|M.thermoresistible__bu DTGGAPAG------------------------------------------
MUL_0423|M.ulcerans_Agy99 RVAGIADGGVVGRVIGGLARALLGMRTDDNDDDPPPEIARLRAALDRIGY
MLBr_00747|M.leprae_Br4923 HSS-----------------------------------------------
Rv1030|M.tuberculosis_H37Rv -----------------------------------PVMLVVLVGAVITTL
Mb1059|M.bovis_AF2122/97 -----------------------------------PVMLVVLVGAVITTL
MAV_1172|M.avium_104 -----------------------------------PVMFIVEIGAAWSTV
Mvan_4760|M.vanbaalenii_PYR-1 -----------------------------------PVMFIVEIGAVWSTI
MMAR_0632|M.marinum_M -----------------------------------PVMFIVELGAVWSTL
MSMEG_5393|M.smegmatis_MC2_155 -----------------------------------PVMFIVEVGAVWSTI
MAB_3253c|M.abscessus_ATCC_199 -----------------------------------PVMFVVTVGSVATTV
Mflv_2244|M.gilvum_PYR-GCK ------PTA------------ALRRRLIICVALSVPVIAMAMAPPLQFTY
TH_4361|M.thermoresistible__bu ------AATGAAGDDHDAEAERWRRRLTISAALSIPVVVLSMIPALQFTH
MUL_0423|M.ulcerans_Agy99 SPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLLASGLTMFFG-AYPW
MLBr_00747|M.leprae_Br4923 -----------------------DIRNIEVLRMAIGAAALTLLGVRRYVF
. :
Rv1030|M.tuberculosis_H37Rv AFLRDLASSTAQENVFNGLVAAFLWFT-----------------------
Mb1059|M.bovis_AF2122/97 AFLRDLASSTAQENVFNGLVAAFLWFT-----------------------
MAV_1172|M.avium_104 LAIVGPT-------WFAWLTVIWLWLT-----------------------
Mvan_4760|M.vanbaalenii_PYR-1 LAFLEPS-------WFAWLIVVWLWLT-----------------------
MMAR_0632|M.marinum_M LAVVDPS-------WFAGLIVAWLWLT-----------------------
MSMEG_5393|M.smegmatis_MC2_155 LAGVNPT-------WFGWLIVAWLWLT-----------------------
MAB_3253c|M.abscessus_ATCC_199 LAVLHPS-------IFAWAITAWLWFT-----------------------
Mflv_2244|M.gilvum_PYR-GCK WQWLSLTLAAPVVVWGAWPFHRATWAN--LRHGTATMDTLISVGTLAAFG
TH_4361|M.thermoresistible__bu WQWLALTLTSPVVVWGAWPFHRAAVAN--LRHGTATMDTLISLGVTAAYL
MUL_0423|M.ulcerans_Agy99 AGWLAFAATIPVQFIAGWPFLVGAVQQ--ARARSANMNTLISLGTLTAFI
MLBr_00747|M.leprae_Br4923 ARPLLLPTTSRLVASGVTIFTGYPFLRGALRFGKTGTDALVSAATIASLI
.
Rv1030|M.tuberculosis_H37Rv --------------------------------------------VLFANF
Mb1059|M.bovis_AF2122/97 --------------------------------------------VLFANF
MAV_1172|M.avium_104 --------------------------------------------VLFANL
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------VLFANL
MMAR_0632|M.marinum_M --------------------------------------------VIFANL
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------VVFANL
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------VVFANL
Mflv_2244|M.gilvum_PYR-GCK WSIYALFWGTAGVPGMTHPFELTIARTDGSGNIYLEAAAGVTTFILAGRY
TH_4361|M.thermoresistible__bu WSLWALFFTAAGMPGMTMTFTLLPADT-GEPHIYLEVAAAVTTFIIAGRY
MUL_0423|M.ulcerans_Agy99 YSTYQLFAGGP---------------------LFFDTAALIIAFVVLGRY
MLBr_00747|M.leprae_Br4923 LREN-------------------------------VVALAVLWLLNIGEY
: ..
Rv1030|M.tuberculosis_H37Rv AEAMAEGRGKAQAAALRKVRSETMANRRT-----AAGNIESVPSSRLDLD
Mb1059|M.bovis_AF2122/97 AEAMAEGRGKAQAAALRKVRSETMANRRT-----AAGNIESVPSSRLDLD
MAV_1172|M.avium_104 AEAVAEGRGKAQAETLRRAKTQTMARRLRDWAPGSTGIEEAVAATALQQG
Mvan_4760|M.vanbaalenii_PYR-1 AEAVAEGRGKAQAESLRKTKTATPARRLTGWAPGTPGREEAVAAALLQPG
MMAR_0632|M.marinum_M AEAVAEGRGKAQADTLRKTKADTMARLLT-----ATGAEEQVTAALLQPG
MSMEG_5393|M.smegmatis_MC2_155 AEAVAEGRGKAQAESLRKTKADTMARRLT-----ESGAEEAVPAPQLRQG
MAB_3253c|M.abscessus_ATCC_199 AEAVAEGRGKAQAASLREVKRDTVARRLVG-DGNGNENEEEVPGSALRPG
Mflv_2244|M.gilvum_PYR-GCK FEARAKRRAGAALRALLELGVRDVTVRRG-------AAEHRIPIDQLRVD
TH_4361|M.thermoresistible__bu FEARAKRQSGAALRALLDMGANDVAVLRD-------GAEKRVPIGELHVG
MUL_0423|M.ulcerans_Agy99 FEATAHGKTREAISKLLDMGAKETRLIVD-------GEEHLVPVDRVQVG
MLBr_00747|M.leprae_Br4923 LQDLTLRRTRRAISALLSGTQDTAWIRLTD--GPQAGTEIQVPIGTVQIG
: : : * :. : .
Rv1030|M.tuberculosis_H37Rv DVVEVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGG
Mb1059|M.bovis_AF2122/97 DVVEVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGG
MAV_1172|M.avium_104 DIVVVEAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGG
Mvan_4760|M.vanbaalenii_PYR-1 DIVVVEAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGG
MMAR_0632|M.marinum_M DIVVVDAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGG
MSMEG_5393|M.smegmatis_MC2_155 DIVVVEAGQTIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGG
MAB_3253c|M.abscessus_ATCC_199 DRVVVEAGQVIPGDGDVVEGIATVDESAITGESAPVVRESGGDRCAVTGG
Mflv_2244|M.gilvum_PYR-GCK DEFVVRPGEKVAADGIIVEGASAVDASMLTGESVPLEVKPG---DRVVGA
TH_4361|M.thermoresistible__bu DVFVVRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPG---DQVVGA
MUL_0423|M.ulcerans_Agy99 DLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVG---DWVAGA
MLBr_00747|M.leprae_Br4923 DEVVVHEHVAIPVDGEVIDGEAVVNQSAITGENLPVSVMAG---SHVHAG
* . * :. ** :: * : *: * :***. *: * * ..
Rv1030|M.tuberculosis_H37Rv TVVLSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALN-ILLAGL
Mb1059|M.bovis_AF2122/97 TVVLSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALN-ILLAGL
MAV_1172|M.avium_104 TTVLSDRIVVQITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLAAL
Mvan_4760|M.vanbaalenii_PYR-1 TTVLSDRIVVKITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLASL
MMAR_0632|M.marinum_M TTVLSDRILVKITQKPGESFIDKMIALVEGADRQKTPNEIALN-ILLASL
MSMEG_5393|M.smegmatis_MC2_155 TTVLSDRIVVRITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLAAL
MAB_3253c|M.abscessus_ATCC_199 TTVLSDRIVVQITAAPGESFVDRMIALVEGASRQKTPNEIALN-ILLASL
Mflv_2244|M.gilvum_PYR-GCK TVNVDGRLVVRAERVGADTQLAQMARLVEDAQNGKAQAQRLADRISGVFV
TH_4361|M.thermoresistible__bu TVNVGGHLQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFV
MUL_0423|M.ulcerans_Agy99 TVNTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFV
MLBr_00747|M.leprae_Br4923 SVVVRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFV
:. . : *: .: : :: * * :: : : . :
Rv1030|M.tuberculosis_H37Rv TIIFLLAVVTLQPFAIYS--------------GGGQRVVVLVALLVCLIP
Mb1059|M.bovis_AF2122/97 TIIFLLAVVTLQPFAIYS--------------GGGQRVVVLVALLVCLIP
MAV_1172|M.avium_104 TIIFVFAVATLQPLAIYSKVNNPGVPDTQALNTSGVTGIVMVSLLVCLIP
Mvan_4760|M.vanbaalenii_PYR-1 TIIFVFAVTTLQPLAIYSKMNNPGVPDSLALNGNGITGIVMVSLLVCLIP
MMAR_0632|M.marinum_M TIIFVFTVVTLQPLAIYSKANNPGVADTVALNANGISGIVMVSLLVCLIP
MSMEG_5393|M.smegmatis_MC2_155 TIIFVFAVATLQPLAIYAKANNPGVPDSLALTGNGISGIVMVALLVCLIP
MAB_3253c|M.abscessus_ATCC_199 TIIFLLAVVALGPMGNYG--------------GEQQDPIKLIALLVCLIP
Mflv_2244|M.gilvum_PYR-GCK PVVLGLAVATLG-FWIGSG------------YPVAAAFTAAVAVLIIACP
TH_4361|M.thermoresistible__bu PIVIALSALTLAGWLLLTD------------APVSAAFTAAVAVLIIACP
MUL_0423|M.ulcerans_Agy99 PVVVRIAAATFAGWTLLAA------------NPVAG-MTAAVSVLIIACP
MLBr_00747|M.leprae_Br4923 PTSFVVSAITLA---------------------ITKDVRRTMTVLLIACP
. . .:. :: :::*: *
Rv1030|M.tuberculosis_H37Rv TTIGALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITL
Mb1059|M.bovis_AF2122/97 TTIGALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITL
MAV_1172|M.avium_104 TTIGALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITL
Mvan_4760|M.vanbaalenii_PYR-1 TTIGALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITL
MMAR_0632|M.marinum_M TTIGALLSAIGIAGMDRLVQRNILAMSGRAVEAAGDVNTLLLDKTGTITL
MSMEG_5393|M.smegmatis_MC2_155 TTIGALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITL
MAB_3253c|M.abscessus_ATCC_199 TTIGALMSAIGIAGMDRLVQHNVLAKSGRAVEAAGDIDTLLMDKTGTITF
Mflv_2244|M.gilvum_PYR-GCK CALGLATPMALMVGTGRGAQLGILIKGPEVLESTRRVDTVIVDKTGTVTT
TH_4361|M.thermoresistible__bu CALGLATPTALLVGTGRGAQLGILIKGPQVLESTRRIDTVVLDKTGTVTT
MUL_0423|M.ulcerans_Agy99 YALGLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTR
MLBr_00747|M.leprae_Br4923 CAVGLATPTAISAAIGNGARRGILIKGGSHLEQAGRVDAILFDKTGTLTV
::* . .. .. . .:* . :* : :::::.*****:*
Rv1030|M.tuberculosis_H37Rv GNRQATEFVPINGVS-AEAVADAAQLSSLADETPEGRSIVVLAKDEFGLR
Mb1059|M.bovis_AF2122/97 GNRQATEFVPINGVS-AEAVADAAQLSSLADETPEGRSIVVLAKDEFGLR
MAV_1172|M.avium_104 GNRQAAAFIPLAGVP-PEELADAAQLSSLADETPEGRSVVVFAKQHFGLR
Mvan_4760|M.vanbaalenii_PYR-1 GNRQASEFVPLTGVT-PEALADAAQLSSLADETPEGRSIVVFAKQEYGLR
MMAR_0632|M.marinum_M GNRQAGAFVHLPGVS-EAELADAAQLSSLADETPEGRSIVVYAKQQYGLR
MSMEG_5393|M.smegmatis_MC2_155 GNRQAAAFVPLTGVT-PESLADAAQLSSLADETPEGRSIVVFAKREFGLR
MAB_3253c|M.abscessus_ATCC_199 GNRQATEFLVAPGIP-HETLAAAARASSLADETPEGRSIVELA-------
Mflv_2244|M.gilvum_PYR-GCK GDMTLVDVFAADGEQ-PDEVLRMAGAVESPSEHPIAAAIAGGARD-----
TH_4361|M.thermoresistible__bu GQMSVTSVHVADGLS-ETELLRLAGAVEHASEHPIARAVATHAAQ-----
MUL_0423|M.ulcerans_Agy99 AQMELTDVIAGKRRQ-PDVVLRIAAAVESGSEHPIGAAIVAGARE-----
MLBr_00747|M.leprae_Br4923 GRPVVTNIVAMHKDWSPEQVLAYAASSEIHSRHPLAEAVIRSTEE-----
. . : * . .. * . :: :
Rv1030|M.tuberculosis_H37Rv ARDEGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAAAAVMKWVRDH
Mb1059|M.bovis_AF2122/97 ARDEGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAAAAVMKWVRDH
MAV_1172|M.avium_104 ARTPGELSQAQWVAFSATTRMSGVDLDGHS----LRKGAASSVAEWVRSQ
Mvan_4760|M.vanbaalenii_PYR-1 ARTPGELAHAAWIEFSATTRMSGVDVDGHR----LRKGATSAVAEWVRSE
MMAR_0632|M.marinum_M ARTPGELAHAQWIEFSATTRMSGVNVDGHL----LRKGAANAVADWVRTQ
MSMEG_5393|M.smegmatis_MC2_155 ARTPGELAEAHWIEFSATTRMSGVNLGEHR----LRKGAAAAVVDWVRGE
MAB_3253c|M.abscessus_ATCC_199 AGTIEESVAGEFVAFTASTRMSGLDTVEGR---QIRKGASDAVFTWVASL
Mflv_2244|M.gilvum_PYR-GCK -------KLGDLPAVDGFANLRGLGVEGDVEGRRLTLGRLRLLSDRSFEI
TH_4361|M.thermoresistible__bu -------TVPPLPEVSDFENHGGNGVSGRVDGHDVRVGRLAWLG---LSA
MUL_0423|M.ulcerans_Agy99 -------RELEVPPATEFTNLAGHGVRGEVGGKSVLVGRRKLVDEQHLRL
MLBr_00747|M.leprae_Br4923 -------RHISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLCAEKVKV
* . : * :
Rv1030|M.tuberculosis_H37Rv GGH-----PTEEVGAIVDGISSGGGTPLVVAEWTDNS----SARAIGVVH
Mb1059|M.bovis_AF2122/97 GGH-----PTEEVGAIVDGISSGGGTPLVVAEWTDNS----SARAIGVVH
MAV_1172|M.avium_104 RGS-----VPHQLGEIVDGISAGGGTPLVVGESVDG-----RARVLGVIH
Mvan_4760|M.vanbaalenii_PYR-1 GGT-----VPTELGDIVDGISAAGGTPLAVGEVREG-----KAAVLGVIH
MMAR_0632|M.marinum_M GGE-----VPPELKATVEAISAGGGTPLAVAQVLDG-----TASVLGVIH
MSMEG_5393|M.smegmatis_MC2_155 GGT-----VPVELFDVVDAISHAGGTPLVVGHVITDDTDPKRAEVLGVIH
MAB_3253c|M.abscessus_ATCC_199 SGVQEDDPVVVAVRKIADQVASEGGTPLVVADHDST-----ETRLLGVIR
Mflv_2244|M.gilvum_PYR-GCK PDD---------LASAVARAEAGGSTAVTVGW---------DGRARGVLM
TH_4361|M.thermoresistible__bu GDR---------LRNAAAQAEAAGHTPVWVAV---------DGRIAGVIV
MUL_0423|M.ulcerans_Agy99 PEQ---------LAAAAADLEERGRTAVYVGQ---------DGQVVGVLA
MLBr_00747|M.leprae_Br4923 SKT---------ASEWVDKLRHQTETPLLFAV---------DGTLVGLIS
. *.: .. *::
Rv1030|M.tuberculosis_H37Rv LKDIVKVGIRERFDEMRRMSIR-TVMITGDNPATAKAIAQEAGVDDFLAE
Mb1059|M.bovis_AF2122/97 LKDIVKVGIRERFDEMRRMSIR-TVMITGDNPATAKAIAQEAGVDDFLAE
MAV_1172|M.avium_104 LKDVVKQGMRERFDEMRRMGIR-TVMITGDNPLTAKAIADEAGVDDFLAE
Mvan_4760|M.vanbaalenii_PYR-1 LKDVVKQGMRERFDEMRRMGIR-TVMITGDNPMTAKAIADEAGVDDFLAE
MMAR_0632|M.marinum_M LKDVVKHGMRERFDEMRRMGIR-TVMITGDNPLTAKAIAEEAGVDDFLAE
MSMEG_5393|M.smegmatis_MC2_155 LKDVVKQGMKQRFDEMRRMGIR-TVMITGDNPLTAKAIADEAGVDDFLAE
MAB_3253c|M.abscessus_ATCC_199 LSDVVKPGMAERFAQMRAMGIR-TVMVTGDNPLTAKQIAAEAGVDDFVAE
Mflv_2244|M.gilvum_PYR-GCK VADAVKPTSAEAISLLKRAGLT-PIMVTGDNEAVARTVAAQVGIDEVVAG
TH_4361|M.thermoresistible__bu VSDTVKDHAAEAIAELRALGAT-PVLLTGDNDRAARTVAAQVGIDDVIAG
MUL_0423|M.ulcerans_Agy99 VADTVKDDAADVVSQLHAMGLQ-VALITGDNARTAAAIAAQVGIDRVLAE
MLBr_00747|M.leprae_Br4923 LRDEVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRAE
: * *: : . :: . ::***: * :* : *:* *
Rv1030|M.tuberculosis_H37Rv ATPEDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TQAA
Mb1059|M.bovis_AF2122/97 ATPEDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TQAA
MAV_1172|M.avium_104 ATPEDKLQLIKREQAGGKLVAMTGDGTNDAPALAQADVGVAMNTG-TSAA
Mvan_4760|M.vanbaalenii_PYR-1 ATPEDKMALIKKEQAGGRLVAMTGDGTNDAPALAQADVGVAMNSG-TSAA
MMAR_0632|M.marinum_M ATPEDKLALIKREQGGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAA
MSMEG_5393|M.smegmatis_MC2_155 ATPEDKLALIKQEQAGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAA
MAB_3253c|M.abscessus_ATCC_199 ATPEDKLELLRKEQQAGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAA
Mflv_2244|M.gilvum_PYR-GCK VLPQDKVDTVTRLQRDGRVVAMVGDGVNDAAALAQADLGMAMGSG-TDVA
TH_4361|M.thermoresistible__bu VLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTG-TDVA
MUL_0423|M.ulcerans_Agy99 VLPADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGIAIGTG-TDVA
MLBr_00747|M.leprae_Br4923 VMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDVA
. * :*: : * * :*.* ***.***.**. **:*:*:. . *..*
Rv1030|M.tuberculosis_H37Rv REAGNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIP
Mb1059|M.bovis_AF2122/97 REAGNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIP
MAV_1172|M.avium_104 KEAGNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIP
Mvan_4760|M.vanbaalenii_PYR-1 KEAGNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIP
MMAR_0632|M.marinum_M KEAGNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIP
MSMEG_5393|M.smegmatis_MC2_155 KEAGNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSISNDIAKYFAIIP
MAB_3253c|M.abscessus_ATCC_199 KEAGNMVDLDSDPTKLIDVVAIGKQLLITRGALTTFSLANDLAKYFAILP
Mflv_2244|M.gilvum_PYR-GCK IEASDLTLVSNDLRAVPDAIRLSRKTLSTIKSNLFWAFA-----------
TH_4361|M.thermoresistible__bu IEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFA-----------
MUL_0423|M.ulcerans_Agy99 IEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFG-----------
MLBr_00747|M.leprae_Br4923 VETADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIA-----------
*:.::. . . :. : . ::.
Rv1030|M.tuberculosis_H37Rv AMFVGLYPVLDKLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFR
Mb1059|M.bovis_AF2122/97 AMFVGLYPVLDKLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFR
MAV_1172|M.avium_104 AMFVALFPGLDLINVMRLHSPQSAILSAVIFNAIIIVLLIPLSLRGVRYT
Mvan_4760|M.vanbaalenii_PYR-1 ALFVGLFPGLDLLNVMRLHSPQSAILSAVIFNAVVIIALIPLSLRGVRYT
MMAR_0632|M.marinum_M ALFVGLFPGLDLLNIMRLHSPQSAILSAVIFNALVIVALIPLALRGVRYT
MSMEG_5393|M.smegmatis_MC2_155 ALFVGLFPGLDLLNIMRLHSPQSAILSAVIFNAIVIVALIPLALKGVRYT
MAB_3253c|M.abscessus_ATCC_199 ALFSGIYPQLGALNIMRLATPQSAILSAVVFNALVIIALVPLALKGVRYR
Mflv_2244|M.gilvum_PYR-GCK ------------YNVAALPLAAAGLLNPMIAGAAMAFSSVFVVTNSLRLR
TH_4361|M.thermoresistible__bu ------------YNVAALPLAAAGLLNPLIAGAAMAFSSVFVVSNSLRLR
MUL_0423|M.ulcerans_Agy99 ------------YNTAAIPLAALGVLNPVVAGAAMGLSSVSVVTNSLRLR
MLBr_00747|M.leprae_Br4923 ------------VNAAGLFIGAGGALSPVLAAVLHNASSVAVVANSSRLI
* : . *..:: . : : .. *
Rv1030|M.tuberculosis_H37Rv AESASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVAL-GVS
Mb1059|M.bovis_AF2122/97 AESASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVAL-GVS
MAV_1172|M.avium_104 PSSASKLLSRNLYIYGLGGIVAPFIGIKAIDLIVQFVPGMS
Mvan_4760|M.vanbaalenii_PYR-1 PSSASKLLSRNLYIFGLGGIIAPFVGIKAIDLIIQLFPGM-
MMAR_0632|M.marinum_M PSSASKLLSRNLSIYGLGGIVAPFIGIKLIDLIIQFLPGMS
MSMEG_5393|M.smegmatis_MC2_155 PSSAAKLLSRNLYIYGLGGIIAPFLGIKLIDLVVQLLPGMS
MAB_3253c|M.abscessus_ATCC_199 PVGAGELLRRNLLIYGLGGVIVPFVGIWLIDLVVRFIPGIG
Mflv_2244|M.gilvum_PYR-GCK AFTPSR-----------------------------------
TH_4361|M.thermoresistible__bu RFTPSR-----------------------------------
MUL_0423|M.ulcerans_Agy99 RFGRDV-----------------------------------
MLBr_00747|M.leprae_Br4923 RYRLD------------------------------------