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MSTTVGSGLLDPTMLWKSLPAAVRKLDPRTLWRNPVMFIVELGAVWSTLLAVVDPSWFAGLIVAWLWLTV IFANLAEAVAEGRGKAQADTLRKTKADTMARLLTATGAEEQVTAALLQPGDIVVVDAGQVIPGDGDVVEG IASVDESAITGESAPVIRESGGDRSAVTGGTTVLSDRILVKITQKPGESFIDKMIALVEGADRQKTPNEI ALNILLASLTIIFVFTVVTLQPLAIYSKANNPGVADTVALNANGISGIVMVSLLVCLIPTTIGALLSAIG IAGMDRLVQRNILAMSGRAVEAAGDVNTLLLDKTGTITLGNRQAGAFVHLPGVSEAELADAAQLSSLADE TPEGRSIVVYAKQQYGLRARTPGELAHAQWIEFSATTRMSGVNVDGHLLRKGAANAVADWVRTQGGEVPP ELKATVEAISAGGGTPLAVAQVLDGTASVLGVIHLKDVVKHGMRERFDEMRRMGIRTVMITGDNPLTAKA IAEEAGVDDFLAEATPEDKLALIKREQGGGRLVAMTGDGTNDAPALAQADVGVAMNTGTSAAKEAGNMVD LDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPALFVGLFPGLDLLNIMRLHSPQSAILSA VIFNALVIVALIPLALRGVRYTPSSASKLLSRNLSIYGLGGIVAPFIGIKLIDLIIQFLPGMS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0632 | kdpB | - | 100% (693) | high-affinity K+ transport system, ATPase chain B, KdpB |
| M. marinum M | MMAR_4876 | ctpV | 5e-56 | 32.29% (573) | metal cation transporter p-type ATPase, CtpV |
| M. marinum M | MMAR_2536 | - | 2e-53 | 31.71% (533) | metal cation transporter p-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1059 | kdpB | 0.0 | 71.01% (690) | potassium-transporting ATPase subunit B |
| M. gilvum PYR-GCK | Mflv_0912 | - | 3e-55 | 31.28% (537) | heavy metal translocating P-type ATPase |
| M. tuberculosis H37Rv | Rv1030 | kdpB | 0.0 | 71.01% (690) | potassium-transporting ATPase subunit B |
| M. leprae Br4923 | MLBr_00747 | ctpC | 1e-46 | 29.59% (615) | putative cation transport ATPase |
| M. abscessus ATCC 19977 | MAB_3253c | - | 0.0 | 66.33% (701) | potassium-transporting ATPase B chain |
| M. avium 104 | MAV_1172 | kdpB | 0.0 | 84.58% (694) | potassium-transporting ATPase subunit B |
| M. smegmatis MC2 155 | MSMEG_5393 | kdpB | 0.0 | 85.37% (697) | potassium-transporting ATPase subunit B |
| M. thermoresistible (build 8) | TH_4361 | - | 2e-53 | 28.49% (667) | PUTATIVE heavy metal translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_0423 | ctpV | 8e-55 | 32.23% (574) | metal cation transporter p-type ATPase, CtpV |
| M. vanbaalenii PYR-1 | Mvan_4760 | - | 0.0 | 86.21% (696) | potassium-transporting ATPase subunit B |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1059|M.bovis_AF2122/97 --------------------------------------------------
Rv1030|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1172|M.avium_104 --------------------------------------------------
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0632|M.marinum_M --------------------------------------------------
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0912|M.gilvum_PYR-GCK --------MALMTTSTSTPVSGANVELRIGGMTCAS---CANRIERKLNK
TH_4361|M.thermoresistible__bu -----------MNTGGMNTVT-----LTVGGMTCAS---CAARVEKRLNR
MUL_0423|M.ulcerans_Agy99 -----------MRVHAN------------GFAIDAT---RAAAIEESVGR
MLBr_00747|M.leprae_Br4923 MTLAMAEQIATADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAK
Mb1059|M.bovis_AF2122/97 --------------------------------------------------
Rv1030|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1172|M.avium_104 --------------------------------------------------
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0632|M.marinum_M --------------------------------------------------
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0912|M.gilvum_PYR-GCK LDGVAATVNYATEKATVT--VPDGYDPALLIAEVEKTGYT--ATLPTPRA
TH_4361|M.thermoresistible__bu IDGVVATVNFATEQATVR--YPDHVDPADLIAAIEATGYT--ASLPAPQR
MUL_0423|M.ulcerans_Agy99 VGGVRAVRAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAA
MLBr_00747|M.leprae_Br4923 CNGVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAHVAAELIPTRAP
Mb1059|M.bovis_AF2122/97 --------------------------------------------------
Rv1030|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1172|M.avium_104 --------------------------------------------------
Mvan_4760|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0632|M.marinum_M --------------------------------------------------
MSMEG_5393|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3253c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0912|M.gilvum_PYR-GCK PAPSDASGDTPN----------------ADGID-DPELASLRHRLR----
TH_4361|M.thermoresistible__bu DTGGAPAGAATG----------------AAGDDHDAEAERWRRRLT----
MUL_0423|M.ulcerans_Agy99 RVAGIADGGVVGRVIGGLARALLGMRTDDNDDDPPPEIARLRAALDRIGY
MLBr_00747|M.leprae_Br4923 HSSDIRN------------------------------IEVLRMAIG----
Mb1059|M.bovis_AF2122/97 -----------------------------MMIARMETSATAAAATSAPRL
Rv1030|M.tuberculosis_H37Rv -----------------------------MMIARMETSATAAAATSAPRL
MAV_1172|M.avium_104 ------------------------------MTVTAIDPAEQAHPAPSAGT
Mvan_4760|M.vanbaalenii_PYR-1 ------------------------------MSVTTAGAAARKHAEPKS-S
MMAR_0632|M.marinum_M ------------------------------MSTTVG--------------
MSMEG_5393|M.smegmatis_MC2_155 ------------------------------MPVHTAQQAVSNHANPKP-T
MAB_3253c|M.abscessus_ATCC_199 ------------------------------MSKSKN--------------
Mflv_0912|M.gilvum_PYR-GCK ------------------------ASTVLTVPVIAMAMIPALQFTYWQWA
TH_4361|M.thermoresistible__bu ------------------------ISAALSIPVVVLSMIPALQFTHWQWL
MUL_0423|M.ulcerans_Agy99 SPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLLASGLTMFFGAYPWA
MLBr_00747|M.leprae_Br4923 ------------------------------AAALTLLGVRRYVFARPLLL
Mb1059|M.bovis_AF2122/97 RLAKRSLFDPMIVRSALPQSLRKLAPRVQARNPVMLVVLVGAVITTLAFL
Rv1030|M.tuberculosis_H37Rv RLAKRSLFDPMIVRSALPQSLRKLAPRVQARNPVMLVVLVGAVITTLAFL
MAV_1172|M.avium_104 KRVQGGLLDPKMLWRSTPDALRKLDPRTLWRNPVMFIVEIGAAWSTVLAI
Mvan_4760|M.vanbaalenii_PYR-1 NKIQGGLLDPNMLWKSLPSALRKLDPRTMWRNPVMFIVEIGAVWSTILAF
MMAR_0632|M.marinum_M ----SGLLDPTMLWKSLPAAVRKLDPRTLWRNPVMFIVELGAVWSTLLAV
MSMEG_5393|M.smegmatis_MC2_155 SQVQGGLLDPKMLWRSLPDALRKLNPRTLWRNPVMFIVEVGAVWSTILAG
MAB_3253c|M.abscessus_ATCC_199 AVVTTGVFDPAQLIKALPLAVRKLDPRHMARNPVMFVVTVGSVATTVLAV
Mflv_0912|M.gilvum_PYR-GCK ---SLTLAAPVIVWAAWPFHRAAWANLRHGTATMDTLISLGTVSAFLWSL
TH_4361|M.thermoresistible__bu ---ALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSL
MUL_0423|M.ulcerans_Agy99 GWLAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLGTLTAFIYST
MLBr_00747|M.leprae_Br4923 PTTSRLVASGVTIFTGYPFLRGALR---FGKTGTDALVSAATIASLILRE
. . * :: . : :
Mb1059|M.bovis_AF2122/97 RDLASSTAQ-----------------ENVFNGLVAAFLWFTVLFANFAEA
Rv1030|M.tuberculosis_H37Rv RDLASSTAQ-----------------ENVFNGLVAAFLWFTVLFANFAEA
MAV_1172|M.avium_104 VGPT------------------------WFAWLTVIWLWLTVLFANLAEA
Mvan_4760|M.vanbaalenii_PYR-1 LEPS------------------------WFAWLIVVWLWLTVLFANLAEA
MMAR_0632|M.marinum_M VDPS------------------------WFAGLIVAWLWLTVIFANLAEA
MSMEG_5393|M.smegmatis_MC2_155 VNPT------------------------WFGWLIVAWLWLTVVFANLAEA
MAB_3253c|M.abscessus_ATCC_199 LHPS------------------------IFAWAITAWLWFTVVFANLAEA
Mflv_0912|M.gilvum_PYR-GCK YALFFGTAGTPGMKHPFELTLAPSHGAANIYLEVAAGVTTFILAGRYFEK
TH_4361|M.thermoresistible__bu WALFFTAAGMPGMTMTFTL-LPADTGEPHIYLEVAAAVTTFIIAGRYFEA
MUL_0423|M.ulcerans_Agy99 YQLFAGGP---------------------LFFDTAALIIAFVVLGRYFEA
MLBr_00747|M.leprae_Br4923 N-------------------------------VVALAVLWLLNIGEYLQD
. : : .. :
Mb1059|M.bovis_AF2122/97 MAEGRGKAQAAALRKVRSETMANRRT-----AAGNIESVPSSRLDLDDVV
Rv1030|M.tuberculosis_H37Rv MAEGRGKAQAAALRKVRSETMANRRT-----AAGNIESVPSSRLDLDDVV
MAV_1172|M.avium_104 VAEGRGKAQAETLRRAKTQTMARRLRDWAPGSTGIEEAVAATALQQGDIV
Mvan_4760|M.vanbaalenii_PYR-1 VAEGRGKAQAESLRKTKTATPARRLTGWAPGTPGREEAVAAALLQPGDIV
MMAR_0632|M.marinum_M VAEGRGKAQADTLRKTKADTMARLLT-----ATGAEEQVTAALLQPGDIV
MSMEG_5393|M.smegmatis_MC2_155 VAEGRGKAQAESLRKTKADTMARRLT-----ESGAEEAVPAPQLRQGDIV
MAB_3253c|M.abscessus_ATCC_199 VAEGRGKAQAASLREVKRDTVARRLVG-DGNGNENEEEVPGSALRPGDRV
Mflv_0912|M.gilvum_PYR-GCK RSKRQAGAALRALLNLGAKDVSVLRD-------GVETKIAIEELMVGDEF
TH_4361|M.thermoresistible__bu RAKRQSGAALRALLDMGANDVAVLRD-------GAEKRVPIGELHVGDVF
MUL_0423|M.ulcerans_Agy99 TAHGKTREAISKLLDMGAKETRLIVD-------GEEHLVPVDRVQVGDLV
MLBr_00747|M.leprae_Br4923 LTLRRTRRAISALLSGTQDTAWIRLTD--GPQAGTEIQVPIGTVQIGDEV
: : * :. : .* .
Mb1059|M.bovis_AF2122/97 EVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGGTVV
Rv1030|M.tuberculosis_H37Rv EVSAGETIPSDGEIIEGIASVDESAITGESAPVIRESGGDRSAVTGGTVV
MAV_1172|M.avium_104 VVEAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
Mvan_4760|M.vanbaalenii_PYR-1 VVEAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
MMAR_0632|M.marinum_M VVDAGQVIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
MSMEG_5393|M.smegmatis_MC2_155 VVEAGQTIPGDGDVVEGIASVDESAITGESAPVIRESGGDRSAVTGGTTV
MAB_3253c|M.abscessus_ATCC_199 VVEAGQVIPGDGDVVEGIATVDESAITGESAPVVRESGGDRCAVTGGTTV
Mflv_0912|M.gilvum_PYR-GCK VVRPGEKIATDGVVTSGSSAVDASMLTGESVPVEVAAG---DTVVGATVN
TH_4361|M.thermoresistible__bu VVRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPG---DQVVGATVN
MUL_0423|M.ulcerans_Agy99 RVRPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVG---DWVAGATVN
MLBr_00747|M.leprae_Br4923 VVHEHVAIPVDGEVIDGEAVVNQSAITGENLPVSVMAG---SHVHAGSVV
* *. ** : * : *: * :***. ** * * ..:.
Mb1059|M.bovis_AF2122/97 LSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALN-ILLAGLTII
Rv1030|M.tuberculosis_H37Rv LSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALN-ILLAGLTII
MAV_1172|M.avium_104 LSDRIVVQITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLAALTII
Mvan_4760|M.vanbaalenii_PYR-1 LSDRIVVKITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLASLTII
MMAR_0632|M.marinum_M LSDRILVKITQKPGESFIDKMIALVEGADRQKTPNEIALN-ILLASLTII
MSMEG_5393|M.smegmatis_MC2_155 LSDRIVVRITQKPGESFIDRMIALVEGANRQKTPNEIALN-ILLAALTII
MAB_3253c|M.abscessus_ATCC_199 LSDRIVVQITAAPGESFVDRMIALVEGASRQKTPNEIALN-ILLASLTII
Mflv_0912|M.gilvum_PYR-GCK AGGRLVVRASRVGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVPIV
TH_4361|M.thermoresistible__bu VGGHLQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIV
MUL_0423|M.ulcerans_Agy99 TDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFVPVV
MLBr_00747|M.leprae_Br4923 VRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTS
. : *: : .: : :: * * :: : : . :.
Mb1059|M.bovis_AF2122/97 FLLAVVTLQPFAIYS--------------GGGQRVVVLVALLVCLIPTTI
Rv1030|M.tuberculosis_H37Rv FLLAVVTLQPFAIYS--------------GGGQRVVVLVALLVCLIPTTI
MAV_1172|M.avium_104 FVFAVATLQPLAIYSKVNNPGVPDTQALNTSGVTGIVMVSLLVCLIPTTI
Mvan_4760|M.vanbaalenii_PYR-1 FVFAVTTLQPLAIYSKMNNPGVPDSLALNGNGITGIVMVSLLVCLIPTTI
MMAR_0632|M.marinum_M FVFTVVTLQPLAIYSKANNPGVADTVALNANGISGIVMVSLLVCLIPTTI
MSMEG_5393|M.smegmatis_MC2_155 FVFAVATLQPLAIYAKANNPGVPDSLALTGNGISGIVMVALLVCLIPTTI
MAB_3253c|M.abscessus_ATCC_199 FLLAVVALGPMGNYG--------------GEQQDPIKLIALLVCLIPTTI
Mflv_0912|M.gilvum_PYR-GCK IAIAVITLGAWLG-AG------------FSVTAAFTAAVAVLVIACPCAL
TH_4361|M.thermoresistible__bu IALSALTLAGWLLLTD------------APVSAAFTAAVAVLIIACPCAL
MUL_0423|M.ulcerans_Agy99 VRIAAATFAGWTLLAA------------NPV-AGMTAAVSVLIIACPYAL
MLBr_00747|M.leprae_Br4923 FVVSAITLA---------------------ITKDVRRTMTVLLIACPCAV
. .:. :: :::*: * ::
Mb1059|M.bovis_AF2122/97 GALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITLGNR
Rv1030|M.tuberculosis_H37Rv GALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNTLLLDKTGTITLGNR
MAV_1172|M.avium_104 GALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITLGNR
Mvan_4760|M.vanbaalenii_PYR-1 GALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITLGNR
MMAR_0632|M.marinum_M GALLSAIGIAGMDRLVQRNILAMSGRAVEAAGDVNTLLLDKTGTITLGNR
MSMEG_5393|M.smegmatis_MC2_155 GALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVNTLLLDKTGTITLGNR
MAB_3253c|M.abscessus_ATCC_199 GALMSAIGIAGMDRLVQHNVLAKSGRAVEAAGDIDTLLMDKTGTITFGNR
Mflv_0912|M.gilvum_PYR-GCK GLATPTALLVGTGRGAQMGVLIKGPEVLESTRKVDTVVLDKTGTVTTGKM
TH_4361|M.thermoresistible__bu GLATPTALLVGTGRGAQLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQM
MUL_0423|M.ulcerans_Agy99 GLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTRAQM
MLBr_00747|M.leprae_Br4923 GLATPTAISAAIGNGARRGILIKGGSHLEQAGRVDAILFDKTGTLTVGRP
* .: .. .. . .:* . :* : ::::::*****:* ..
Mb1059|M.bovis_AF2122/97 QATEFVPI-NGVSAEAVADAAQLSSLADETPEGRSIVVLAKDEFGLRARD
Rv1030|M.tuberculosis_H37Rv QATEFVPI-NGVSAEAVADAAQLSSLADETPEGRSIVVLAKDEFGLRARD
MAV_1172|M.avium_104 QAAAFIPL-AGVPPEELADAAQLSSLADETPEGRSVVVFAKQHFGLRART
Mvan_4760|M.vanbaalenii_PYR-1 QASEFVPL-TGVTPEALADAAQLSSLADETPEGRSIVVFAKQEYGLRART
MMAR_0632|M.marinum_M QAGAFVHL-PGVSEAELADAAQLSSLADETPEGRSIVVYAKQQYGLRART
MSMEG_5393|M.smegmatis_MC2_155 QAAAFVPL-TGVTPESLADAAQLSSLADETPEGRSIVVFAKREFGLRART
MAB_3253c|M.abscessus_ATCC_199 QATEFLVA-PGIPHETLAAAARASSLADETPEGRSIVELA-------AGT
Mflv_0912|M.gilvum_PYR-GCK ALVDVIAA-PGTERAELLRLAGALENASEHPIAHAIATAAAE--------
TH_4361|M.thermoresistible__bu SVTSVHVA-DGLSETELLRLAGAVEHASEHPIARAVATHAAQ--------
MUL_0423|M.ulcerans_Agy99 ELTDVIAG-KRRQPDVVLRIAAAVESGSEHPIGAAIVAGARE--------
MLBr_00747|M.leprae_Br4923 VVTNIVAMHKDWSPEQVLAYAASSEIHSRHPLAEAVIRSTEE--------
. : * . .. * . :: :
Mb1059|M.bovis_AF2122/97 EGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAAAAVMKWVRDHGGH
Rv1030|M.tuberculosis_H37Rv EGVMSHARFVPFTAETRMSGVDLAEVSGIRRIRKGAAAAVMKWVRDHGGH
MAV_1172|M.avium_104 PGELSQAQWVAFSATTRMSGVDLDGHS----LRKGAASSVAEWVRSQRGS
Mvan_4760|M.vanbaalenii_PYR-1 PGELAHAAWIEFSATTRMSGVDVDGHR----LRKGATSAVAEWVRSEGGT
MMAR_0632|M.marinum_M PGELAHAQWIEFSATTRMSGVNVDGHL----LRKGAANAVADWVRTQGGE
MSMEG_5393|M.smegmatis_MC2_155 PGELAEAHWIEFSATTRMSGVNLGEHR----LRKGAAAAVVDWVRGEGGT
MAB_3253c|M.abscessus_ATCC_199 IEESVAGEFVAFTASTRMSGLDTVEGR---QIRKGASDAVFTWVASLSGV
Mflv_0912|M.gilvum_PYR-GCK ----EVGTLPTPEGFANVEGKGVQGVVDGHAVVVGRESLLADWAQHLSPD
TH_4361|M.thermoresistible__bu ----TVPPLPEVSDFENHGGNGVSGRVDGHDVRVGR---LAWLGLSAGDR
MUL_0423|M.ulcerans_Agy99 ----RELEVPPATEFTNLAGHGVRGEVGGKSVLVGRRKLVDEQHLRLPEQ
MLBr_00747|M.leprae_Br4923 ----RHISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLCAEKVKVSKT
* . : * :
Mb1059|M.bovis_AF2122/97 -----PTEEVGAIVDGISSGGGTPLVVAEWTDNS----SARAIGVVHLKD
Rv1030|M.tuberculosis_H37Rv -----PTEEVGAIVDGISSGGGTPLVVAEWTDNS----SARAIGVVHLKD
MAV_1172|M.avium_104 -----VPHQLGEIVDGISAGGGTPLVVGESVDG-----RARVLGVIHLKD
Mvan_4760|M.vanbaalenii_PYR-1 -----VPTELGDIVDGISAAGGTPLAVGEVREG-----KAAVLGVIHLKD
MMAR_0632|M.marinum_M -----VPPELKATVEAISAGGGTPLAVAQVLDG-----TASVLGVIHLKD
MSMEG_5393|M.smegmatis_MC2_155 -----VPVELFDVVDAISHAGGTPLVVGHVITDDTDPKRAEVLGVIHLKD
MAB_3253c|M.abscessus_ATCC_199 QEDDPVVVAVRKIADQVASEGGTPLVVADHDST-----ETRLLGVIRLSD
Mflv_0912|M.gilvum_PYR-GCK ---------LSRAKAGAEAQGKTVVAVGW---------DGQARGVLVVAD
TH_4361|M.thermoresistible__bu ---------LRNAAAQAEAAGHTPVWVAV---------DGRIAGVIVVSD
MUL_0423|M.ulcerans_Agy99 ---------LAAAAADLEERGRTAVYVGQ---------DGQVVGVLAVAD
MLBr_00747|M.leprae_Br4923 ---------ASEWVDKLRHQTETPLLFAV---------DGTLVGLISLRD
* : .. *:: : *
Mb1059|M.bovis_AF2122/97 IVKVGIRERFDEMRRMSIR-TVMITGDNPATAKAIAQEAGVDDFLAEATP
Rv1030|M.tuberculosis_H37Rv IVKVGIRERFDEMRRMSIR-TVMITGDNPATAKAIAQEAGVDDFLAEATP
MAV_1172|M.avium_104 VVKQGMRERFDEMRRMGIR-TVMITGDNPLTAKAIADEAGVDDFLAEATP
Mvan_4760|M.vanbaalenii_PYR-1 VVKQGMRERFDEMRRMGIR-TVMITGDNPMTAKAIADEAGVDDFLAEATP
MMAR_0632|M.marinum_M VVKHGMRERFDEMRRMGIR-TVMITGDNPLTAKAIAEEAGVDDFLAEATP
MSMEG_5393|M.smegmatis_MC2_155 VVKQGMKQRFDEMRRMGIR-TVMITGDNPLTAKAIADEAGVDDFLAEATP
MAB_3253c|M.abscessus_ATCC_199 VVKPGMAERFAQMRAMGIR-TVMVTGDNPLTAKQIAAEAGVDDFVAEATP
Mflv_0912|M.gilvum_PYR-GCK TVKPTSAQAISQMRDLGLT-PVLLTGDNEAVARQIAAEVGIDTVIAEVMP
TH_4361|M.thermoresistible__bu TVKDHAAEAIAELRALGAT-PVLLTGDNDRAARTVAAQVGIDDVIAGVLP
MUL_0423|M.ulcerans_Agy99 TVKDDAADVVSQLHAMGLQ-VALITGDNARTAAAIAAQVGIDRVLAEVLP
MLBr_00747|M.leprae_Br4923 EVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRAEVMP
*: : . ::: . .::***: * :* : *:* * . *
Mb1059|M.bovis_AF2122/97 EDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TQAAREA
Rv1030|M.tuberculosis_H37Rv EDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TQAAREA
MAV_1172|M.avium_104 EDKLQLIKREQAGGKLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
Mvan_4760|M.vanbaalenii_PYR-1 EDKMALIKKEQAGGRLVAMTGDGTNDAPALAQADVGVAMNSG-TSAAKEA
MMAR_0632|M.marinum_M EDKLALIKREQGGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
MSMEG_5393|M.smegmatis_MC2_155 EDKLALIKQEQAGGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
MAB_3253c|M.abscessus_ATCC_199 EDKLELLRKEQQAGRLVAMTGDGTNDAPALAQADVGVAMNTG-TSAAKEA
Mflv_0912|M.gilvum_PYR-GCK KDKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGTG-TDVAIEA
TH_4361|M.thermoresistible__bu AEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTG-TDVAIEA
MUL_0423|M.ulcerans_Agy99 ADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGIAIGTG-TDVAIEA
MLBr_00747|M.leprae_Br4923 EDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDVAVET
:*: : * * *.* ***.***.**. **:*:*:. . *..* *:
Mb1059|M.bovis_AF2122/97 GNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAMF
Rv1030|M.tuberculosis_H37Rv GNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAMF
MAV_1172|M.avium_104 GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPAMF
Mvan_4760|M.vanbaalenii_PYR-1 GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPALF
MMAR_0632|M.marinum_M GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSIANDIAKYFAIIPALF
MSMEG_5393|M.smegmatis_MC2_155 GNMVDLDSDPTKLIEIVEIGKQLLITRGALTTFSISNDIAKYFAIIPALF
MAB_3253c|M.abscessus_ATCC_199 GNMVDLDSDPTKLIDVVAIGKQLLITRGALTTFSLANDLAKYFAILPALF
Mflv_0912|M.gilvum_PYR-GCK SDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFA--------------
TH_4361|M.thermoresistible__bu SDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFA--------------
MUL_0423|M.ulcerans_Agy99 SDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFG--------------
MLBr_00747|M.leprae_Br4923 ADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIA--------------
.::. . . :. : . ::.
Mb1059|M.bovis_AF2122/97 VGLYPVLDKLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFRAES
Rv1030|M.tuberculosis_H37Rv VGLYPVLDKLNVMALHSPRSAILSAVIFNALVIVALIPLALRGVRFRAES
MAV_1172|M.avium_104 VALFPGLDLINVMRLHSPQSAILSAVIFNAIIIVLLIPLSLRGVRYTPSS
Mvan_4760|M.vanbaalenii_PYR-1 VGLFPGLDLLNVMRLHSPQSAILSAVIFNAVVIIALIPLSLRGVRYTPSS
MMAR_0632|M.marinum_M VGLFPGLDLLNIMRLHSPQSAILSAVIFNALVIVALIPLALRGVRYTPSS
MSMEG_5393|M.smegmatis_MC2_155 VGLFPGLDLLNIMRLHSPQSAILSAVIFNAIVIVALIPLALKGVRYTPSS
MAB_3253c|M.abscessus_ATCC_199 SGIYPQLGALNIMRLATPQSAILSAVVFNALVIIALVPLALKGVRYRPVG
Mflv_0912|M.gilvum_PYR-GCK ---------YNVAAIPVAALGMLNPMLAGAAMAFSSVFVVGNSLRLRGFT
TH_4361|M.thermoresistible__bu ---------YNVAALPLAAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFT
MUL_0423|M.ulcerans_Agy99 ---------YNTAAIPLAALGVLNPVVAGAAMGLSSVSVVTNSLRLRRFG
MLBr_00747|M.leprae_Br4923 ---------VNAAGLFIGAGGALSPVLAAVLHNASSVAVVANSSRLIRYR
* : . *..:: . : : .. *
Mb1059|M.bovis_AF2122/97 ASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVAL-GVS
Rv1030|M.tuberculosis_H37Rv ASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVAL-GVS
MAV_1172|M.avium_104 ASKLLSRNLYIYGLGGIVAPFIGIKAIDLIVQFVPGMS
Mvan_4760|M.vanbaalenii_PYR-1 ASKLLSRNLYIFGLGGIIAPFVGIKAIDLIIQLFPGM-
MMAR_0632|M.marinum_M ASKLLSRNLSIYGLGGIVAPFIGIKLIDLIIQFLPGMS
MSMEG_5393|M.smegmatis_MC2_155 AAKLLSRNLYIYGLGGIIAPFLGIKLIDLVVQLLPGMS
MAB_3253c|M.abscessus_ATCC_199 AGELLRRNLLIYGLGGVIVPFVGIWLIDLVVRFIPGIG
Mflv_0912|M.gilvum_PYR-GCK STSSAPTH------------------------------
TH_4361|M.thermoresistible__bu PSR-----------------------------------
MUL_0423|M.ulcerans_Agy99 RDV-----------------------------------
MLBr_00747|M.leprae_Br4923 LD------------------------------------