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MREHTAALTVAATCVLVAACGGGGNEGATSTTPSTLLSPTTSAPAPPTTSTPPPPVAESALDGLLLSPAE IDTVVGATGMAVAGTSTSLAEDITVPPDAPEEKKACVGIAGTAEAQAYAGSGSTAVRDQALRAPNDSGAT LSAGQAVVLFPTADEAATFFAESAQKWPLCRGYNAGGSPVTVGDVSSDNGMLVTSITIQSEDEPTLCERA LTMKNNIVIDVSTCGGSSDSAVRIADQIAARVPGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4738 | - | - | 100% (245) | putative lipoprotein LppH |
| M. vanbaalenii PYR-1 | Mvan_4460 | - | 1e-30 | 35.46% (251) | putative lipoprotein LppH |
| M. vanbaalenii PYR-1 | Mvan_3878 | - | 7e-18 | 32.00% (200) | hypothetical protein Mvan_3878 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3607 | lppH | 2e-26 | 36.48% (244) | lipoprotein LppH |
| M. gilvum PYR-GCK | Mflv_2235 | - | 3e-28 | 35.10% (245) | putative lipoprotein LppH |
| M. tuberculosis H37Rv | Rv3576 | lppH | 1e-26 | 35.66% (244) | lipoprotein LppH |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2422c | - | 9e-09 | 27.78% (252) | hypothetical protein MAB_2422c |
| M. marinum M | MMAR_5074 | lppH | 1e-25 | 35.15% (239) | lipoprotein LppH |
| M. avium 104 | MAV_2123 | - | 2e-29 | 36.86% (255) | PknM protein |
| M. smegmatis MC2 155 | MSMEG_4554 | - | 7e-17 | 31.25% (208) | serine/threonine-protein kinase PknH, putative |
| M. thermoresistible (build 8) | TH_3756 | - | 1e-32 | 40.68% (236) | PUTATIVE putative conserved lipoprotein LppH |
| M. ulcerans Agy99 | MUL_4150 | lppH | 4e-26 | 35.15% (239) | lipoprotein LppH |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3607|M.bovis_AF2122/97 ----MGKQLAALAALVG-ACMLAAGCTNVVDGTAVA--------------
Rv3576|M.tuberculosis_H37Rv ----MGKQLAALAALVG-ACMLAAGCTNVVDGTAVA--------------
MMAR_5074|M.marinum_M ----MRQRVAALAALVGGAGMLVTGCTNIVDGNAVA--------------
MUL_4150|M.ulcerans_Agy99 ----MRQRVAALAALVGGAGMLVTGCTNIVDGNAVA--------------
Mvan_4738|M.vanbaalenii_PYR-1 ------MREHTAALTVAATCVLVAACGGGGNEGATSTTPSTLLSPTTSAP
MAV_2123|M.avium_104 ------MRRLAATLAAAG--MLVAGCG-AGNHGAAS-----------SST
Mflv_2235|M.gilvum_PYR-GCK ---------MRRAVAIAGIAIMVTGCA--STSSAES-----------AEP
TH_3756|M.thermoresistible__bu ------------------MGVLVAGCG--STGHAES-----------TTA
MSMEG_4554|M.smegmatis_MC2_155 MTPGRRWTRLCTAGAAAAVMCLLSGCVTVVGGTATR--------------
MAB_2422c|M.abscessus_ATCC_199 ------MRYGMTLGCAVTTAVLMAGCTQPSEGIKPVAAPSTTTAEMPMTA
: :.*
Mb3607|M.bovis_AF2122/97 ADKSGPLHQDPIPVSALEGLLLDLSQINAALGA---TSMKVWFNAKAMWD
Rv3576|M.tuberculosis_H37Rv ADKSGPLHQDPIPVSALEGLLLDLSQINAALGA---TSMKVWFNAKAMWD
MMAR_5074|M.marinum_M ADMSGPLNQTPIAVSALDDLLLDVNQIDSALGA---TSMKVWFNAKAMWD
MUL_4150|M.ulcerans_Agy99 ADMSGPLNQTPIAVSALDDLLLDVSQIDSALGA---TSMKVWFNAKAMWD
Mvan_4738|M.vanbaalenii_PYR-1 APPTTSTPPPPVAESALDGLLLSPAEIDTVVGA---TGMAVAGTSTSLAE
MAV_2123|M.avium_104 ATGSTASPKTPLARGALPDLMLSPNDIDTALGV---TGTTSDPPFTALGE
Mflv_2235|M.gilvum_PYR-GCK P--TRTMIPRPLVEREIGEVLLSPEEIAALMGV---PAMTVIEAQTSLSD
TH_3756|M.thermoresistible__bu PSTTKTLIPRPLVERELPGLLLSPEQVNAAMGT---TDMAIISSQTSLSD
MSMEG_4554|M.smegmatis_MC2_155 -DPAAPPPGAAVTEVDLDNLLLPVTELGDIVGS---DDLTVTVELDQFND
MAB_2422c|M.abscessus_ATCC_199 GTSAPPSVPTTTKAPAPPPLVVTPDKIESILGSRADVGKILGTTLEYDNN
: . . ::: .: :* :
Mb3607|M.bovis_AF2122/97 WS-----KSVADKNCLAIDGPAQEKVYAGTGWTAMRGQRLDDSINDSKKR
Rv3576|M.tuberculosis_H37Rv WS-----KSVADKNCLAIDGPAQEKVYAGTGWTAMRGQRLDDSIDDSKKR
MMAR_5074|M.marinum_M WS-----KNISDKNCLAVDGPAQDEVYAGTGWTAMRGQRMDDSVDDSKRR
MUL_4150|M.ulcerans_Agy99 WS-----KNISDKNCLAVDGPAQDEVYAGTGWTAMRGQRMDDSVDDSKRR
Mvan_4738|M.vanbaalenii_PYR-1 DITVPPDAPEEKKACVGIAGTAEAQAYAGSGSTAVRDQALRAPNDSGATL
MAV_2123|M.avium_104 DPVRRTDYTFP-AECKYTTHAGLASEYAGSGSTAVYGYHDLAPTPAGANQ
Mflv_2235|M.gilvum_PYR-GCK H----SDIMAP-IECLAIDGAGELQVYANSDYRASRDQSLND--GEGWKT
TH_3756|M.thermoresistible__bu H----SNTMAP-PECLALDGAGEADVYADSGYRAARDHSLNN--GDNFTH
MSMEG_4554|M.smegmatis_MC2_155 SS-----AAMDDPDCLAAAFGAQERVYAGTGWTAVRDQIVREPGSFSPHW
MAB_2422c|M.abscessus_ATCC_199 DSSPPTDQIGGAPDCAALDIPTASQL--GSEWTTYRWNYYRETKDRTAYI
* .: :
Mb3607|M.bovis_AF2122/97 DHY--AIQAVVGFPTAHDAEEFYSSSVQSWSSCSNRRFVEVTPGQ-DDAA
Rv3576|M.tuberculosis_H37Rv DHY--AIQAVVGFPTAHDAEEFYSSSVQSWSSCSNRRFVEVTPGQ-DDAA
MMAR_5074|M.marinum_M KHY--AIQAVVAFPSAHDASAFYNSSVRSWGNCSNRRFTDVSTDQ-PDTI
MUL_4150|M.ulcerans_Agy99 KHY--AIQAVVAFPSAHDASAFYNSSVRSWGNCSNRRFTDVSTDQ-PDTI
Mvan_4738|M.vanbaalenii_PYR-1 SAG----QAVVLFPTADEAATFFAESAQKWPLCRGYN----AGGS----P
MAV_2123|M.avium_104 LESPEVYQFVVLFPSPEQASAFLSASSARWPACANRQDTVPADGTNPELR
Mflv_2235|M.gilvum_PYR-GCK YVK----QAVVLFPYLEKAGEFFDASVAQWPACREYTHT--QSGS----V
TH_3756|M.thermoresistible__bu YAK----QAVVLFPLAETARAFFEASAEQWPACHEYRHT--QSGT----K
MSMEG_4554|M.smegmatis_MC2_155 IEQ-----VVVLFTSDLHARDFFDQSRETWRGCVGTLTTYDIDQM--PLE
MAB_2422c|M.abscessus_ATCC_199 VSQ-----VAVLYPTREEAATAFVHAFPKSAAKTCVGAEITKQDQ----K
.* :. * :
Mb3607|M.bovis_AF2122/97 WTVADVVNDNGMLSSSQVQEGGDG-----WTCQRALTARNNVTIDIVTCA
Rv3576|M.tuberculosis_H37Rv WTVADVVNDNGMLSSSQVQEGGDG-----WTCQRALTARNNVTIDIVTCA
MMAR_5074|M.marinum_M WTVSDVVNDNGMLSTSQVQEAGDG-----WTCQRALTVRNNVAIDVVTCA
MUL_4150|M.ulcerans_Agy99 WTVSDVVNDNGMLSTSQVQEAGDG-----WTCQRALTVRNNVAIDVVTCA
Mvan_4738|M.vanbaalenii_PYR-1 VTVGDVSSDNGMLVTSITIQSE----DEPTLCERALTMKNNIVIDVSTCG
MAV_2123|M.avium_104 WKVGPVTNANGMLSSQVTVTVNGNGVNVTMPCQRALTARNNIVIDVDACR
Mflv_2235|M.gilvum_PYR-GCK WNPGEITSADRTLS-TVAMQRDAA--APGWGCGRALVHRNNVIVDVNTCS
TH_3756|M.thermoresistible__bu WYVAELTRDGDILK-AITVQRDAG--HPGWGCGRALVLRNNIIGDVNTCS
MSMEG_4554|M.smegmatis_MC2_155 WVVGEVTAEESTISQLSVPETAVR-----GGCHHALSVAANLVAEAWACG
MAB_2422c|M.abscessus_ATCC_199 WTISNIAEISDNTAKWTQLQALQR---TPWRCFFDFRNKNNVLFGAYLCQ
. : * : *: *
Mb3607|M.bovis_AF2122/97 YSQPDLVAIGIANQIAAKVAKQ-
Rv3576|M.tuberculosis_H37Rv YSQPDLVAIGIANQIAAKVAKQ-
MMAR_5074|M.marinum_M YSQSGSVAADVAQQIAAKAAKQ-
MUL_4150|M.ulcerans_Agy99 YSQSGSVAADVAQQIAAKAAKQ-
Mvan_4738|M.vanbaalenii_PYR-1 -GSS-DSAVRIADQIAARVPGE-
MAV_2123|M.avium_104 -KDVGDLGIDIAKQIAGKVDKQ-
Mflv_2235|M.gilvum_PYR-GCK -AAPGDSAVRIAHQIADKVDAQW
TH_3756|M.thermoresistible__bu -ADPGDSAVRIAQQIGENVDAVW
MSMEG_4554|M.smegmatis_MC2_155 -EGVEDQASEIVDQIVANIE---
MAB_2422c|M.abscessus_ATCC_199 YGDGVPGVTTITDRIAAWIPQ--
:..:*