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RYGMTLGCAVTTAVLMAGCTQPSEGIKPVAAPSTTTAEMPMTAGTSAPPSVPTTTKAPAPPPLVVTPDKI ESILGSRADVGKILGTTLEYDNNDSSPPTDQIGGAPDCAALDIPTASQLGSEWTTYRWNYYRETKDRTAY IVSQVAVLYPTREEAATAFVHAFPKSAAKTCVGAEITKQDQKWTISNIAEISDNTAKWTQLQALQRTPWR CFFDFRNKNNVLFGAYLCQYGDGVPGVTTITDRIAAWIPQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2422c | - | - | 100% (251) | hypothetical protein MAB_2422c |
| M. abscessus ATCC 19977 | MAB_2420c | - | 2e-44 | 41.27% (252) | hypothetical protein MAB_2420c |
| M. abscessus ATCC 19977 | MAB_2421c | - | 1e-33 | 31.36% (236) | hypothetical protein MAB_2421c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1297c | pknH | 7e-07 | 23.61% (233) | transmembrane serine/threonine-protein kinase H |
| M. gilvum PYR-GCK | Mflv_1314 | - | 1e-05 | 22.60% (208) | hypothetical protein Mflv_1314 |
| M. tuberculosis H37Rv | Rv1266c | pknH | 9e-07 | 23.61% (233) | transmembrane serine/threonine-protein kinase H |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4171 | - | 2e-06 | 23.68% (190) | transmembrane serine/threonine-protein kinase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4554 | - | 2e-06 | 25.36% (209) | serine/threonine-protein kinase PknH, putative |
| M. thermoresistible (build 8) | TH_3756 | - | 1e-05 | 22.22% (207) | PUTATIVE putative conserved lipoprotein LppH |
| M. ulcerans Agy99 | MUL_4150 | lppH | 9e-05 | 21.62% (148) | lipoprotein LppH |
| M. vanbaalenii PYR-1 | Mvan_4738 | - | 1e-08 | 27.78% (252) | putative lipoprotein LppH |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAE
Rv1266c|M.tuberculosis_H37Rv MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAE
MMAR_4171|M.marinum_M MSDAQGSRVGSTFGPYRLTRLLGRGGMGEVYEAEHTVKEWTVAVKLMSET
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 FSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTD
Rv1266c|M.tuberculosis_H37Rv FSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTD
MMAR_4171|M.marinum_M FSKDPVFRERMKREARITGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTD
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRD
Rv1266c|M.tuberculosis_H37Rv LDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRD
MMAR_4171|M.marinum_M LDNLLKRFGPLTPPRAVAIITQVASALDAAHAAGVMHRDVKPQNILVTRE
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
Rv1266c|M.tuberculosis_H37Rv DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
MMAR_4171|M.marinum_M DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVV
Rv1266c|M.tuberculosis_H37Rv LACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVV
MMAR_4171|M.marinum_M LACVLHECLTGSPPYRADSASMLVTAHMMDPIPQPSTVRAGIPKAFDTVI
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG--
Rv1266c|M.tuberculosis_H37Rv ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP
MMAR_4171|M.marinum_M ARGMAKQPGDRYASAGDLALAAHEALSNPDQDHAADILRRSQEATLPGPP
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ---------TAAVTAQPPTMPTVTPPPIQAAP------------------
Rv1266c|M.tuberculosis_H37Rv KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAG----
MMAR_4171|M.marinum_M DPAAPPTMPATAAAPPARPGPAATPPRPAPTPQQPPYYPAAAAPAAGSPP
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
Mvan_4738|M.vanbaalenii_PYR-1 ----------------------------------------------MREH
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ------------------------------TGQPSWAPNSGPMPASGPTP
Rv1266c|M.tuberculosis_H37Rv -------------------------QRPGPTGQPSWAPNSGPMPASGPTP
MMAR_4171|M.marinum_M SGPSAVAGPPRGVAPSGPAGPSGPIPRPPAAGQPGWQQASGPIPASQPTP
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2422c|M.abscessus_ATCC_199 ------------------------------------------------MR
Mflv_1314|M.gilvum_PYR-GCK --------------------------------------------------
TH_3756|M.thermoresistible__bu --------MGVLVAGCG-------------------------STGH--AE
Mvan_4738|M.vanbaalenii_PYR-1 TAALTVAATCVLVAACG-------------------------GGGNEGAT
MUL_4150|M.ulcerans_Agy99 ----MRQRVAALAALVG-------------------------GAGMLVTG
Mb1297c|M.bovis_AF2122/97 TPQYYQGGGWG-APPSG---GPSPWAQTP-----RKTNPWPLVAGAAAVV
Rv1266c|M.tuberculosis_H37Rv TPQYYQGGGWG-APPSG---GPSPWAQTP-----RKTNPWPLVAGAAAVV
MMAR_4171|M.marinum_M SPPYYQGAGWGGAPPPGQPAGPSTWNQGPQGPGPRGRNPWPIVA-AVAIV
MSMEG_4554|M.smegmatis_MC2_155 ---MTPGRRWTRLCTAG----------------------------AAAAV
MAB_2422c|M.abscessus_ATCC_199 YGMTLGCAVTTAVLMAG------------------------CTQPSEGIK
Mflv_1314|M.gilvum_PYR-GCK ------------MSIGG-----------------------------DPRP
*
TH_3756|M.thermoresistible__bu STT------------APSTTKTLIPRPLVERELPGLLLSPEQVNAAMGT-
Mvan_4738|M.vanbaalenii_PYR-1 STTPSTLLSPTTSAPAPPTTSTPPP-PVAESALDGLLLSPAEIDTVVGA-
MUL_4150|M.ulcerans_Agy99 CTN-----IVDGNAVAADMSGPLNQTPIAVSALDDLLLDVSQIDSALGA-
Mb1297c|M.bovis_AF2122/97 LVLVLGAIGIWIANRP-KPVQPP--QPVAEERLSALLLNSSEVNAVMGS-
Rv1266c|M.tuberculosis_H37Rv LVLVLGAIGIWIAIRP-KPVQPP--QPVAEERLSALLLNSSEVNAVMGS-
MMAR_4171|M.marinum_M LVLIVGGIGVWMITQPPKPSPPP--KPIAEDRLSSLLLSPAEVNSVMGA-
MSMEG_4554|M.smegmatis_MC2_155 MCLLSGCVTVVGGTATRDPAAPPPGAAVTEVDLDNLLLPVTELGDIVGS-
MAB_2422c|M.abscessus_ATCC_199 PVAAPSTTTAEMPMTAGTSAPPSVPTTTKAPAPPPLVVTPDKIESILGSR
Mflv_1314|M.gilvum_PYR-GCK GRCRVLLVALVAAAAALTSAAPATARPSDPGVVNYAVLNKGSVGNIVGAR
. . . :: .: :*:
TH_3756|M.thermoresistible__bu TDMAIISSQTSLSDHSNT--MAPPE---CLALDGAGEADVYADSGYRAAR
Mvan_4738|M.vanbaalenii_PYR-1 TGMAVAGTSTSLAEDITVPPDAPEEKKACVGIAGTAEAQAYAGSGSTAVR
MUL_4150|M.ulcerans_Agy99 TSMKVWFNAKAMWDWSKN--ISDKN---CLAVDGPAQDEVYAGTGWTAMR
Mb1297c|M.bovis_AF2122/97 SSMQPGKPITSMDSSPVT--VSLPD---CQGALYTSQDPVYAGTGYTAIN
Rv1266c|M.tuberculosis_H37Rv SSMQPGKPITSMDSSPVT--VSLPD---CQGALYTSQDPVYAGTGYTAIN
MMAR_4171|M.marinum_M SNIQPGKPITSMDASPVT--LSLPE---CQGALYTSQDPVYSGTGYTAIS
MSMEG_4554|M.smegmatis_MC2_155 DDLTVTVELDQFNDSSAA--MDDPD---CLAAAFGAQERVYAGTGWTAVR
MAB_2422c|M.abscessus_ATCC_199 ADVGKILGTTLEYDNNDSSPPTDQIGGAPDCAALDIPTASQLGSEWTTYR
Mflv_1314|M.gilvum_PYR-GCK MGFESTFAAPFQAFYVDN--------PACNNWADIGLPEVYNDPDLAAFS
.. .. :
TH_3756|M.thermoresistible__bu DHSLN--NGDNFT--HYAKQAVVLFPLAETARAFFEASAEQWPACHEYRH
Mvan_4738|M.vanbaalenii_PYR-1 DQALRAPNDSGAT--LSAGQAVVLFPTADEAATFFAESAQKWPLCRGY--
MUL_4150|M.ulcerans_Agy99 GQRMDDSVDDSKRRKHYAIQAVVAFPSAHDASAFYNSSVRSWGNCSNRRF
Mb1297c|M.bovis_AF2122/97 GLISSEPGDNYEH---WVNQAVVAFPTADKARAFVQTSADKWKNCAGKTV
Rv1266c|M.tuberculosis_H37Rv GLISSEPGDNYEH---WVNQAVVAFPTADKARAFVQTSADKWKNCAGKTV
MMAR_4171|M.marinum_M GLVASEPGDNNDH---WVNQAVVSFPSAAKASSFVETMAGKWKNCAGKTV
MSMEG_4554|M.smegmatis_MC2_155 DQIVREPGSFSPH---WIEQVVVLFTSDLHARDFFDQSRETWRGCVGTLT
MAB_2422c|M.abscessus_ATCC_199 WNYYRETKDRTAY---IVSQVAVLYPTREEAATAFVHAFPKSAAKTCVGA
Mflv_1314|M.gilvum_PYR-GCK GAATQESPTDATH---LVKQAVGVFATNDAARRAMYRVVDRTVACNGQTT
*.. :. *
TH_3756|M.thermoresistible__bu TQSGTK-----WYVAELTRD-GDILKAITVQRDAGHPGWGCGRALVLRNN
Mvan_4738|M.vanbaalenii_PYR-1 NAGGSP-----VTVGDVSSDNGMLVTSITIQSED-EPTL-CERALTMKNN
MUL_4150|M.ulcerans_Agy99 TDVSTDQPDTIWTVSDVVNDNGMLSTSQVQEAGD---GWTCQRALTVRNN
Mb1297c|M.bovis_AF2122/97 TVTNKAK-TYRWTFADVKGSPPTITVIDTQEGAEG---WECQRAMSVANN
Rv1266c|M.tuberculosis_H37Rv TVTNKAK-TYRWTFADVKGSPPTITVIDTQEGAEG---WECQRAMSVANN
MMAR_4171|M.marinum_M TVTNKSK-TYRWTFAQVVGSPPRITMLETQEGAEG---WECQRAMSVANN
MSMEG_4554|M.smegmatis_MC2_155 TYDIDQM-PLEWVVGEVTAEESTISQLSVPETAVR---GGCHHALSVAAN
MAB_2422c|M.abscessus_ATCC_199 EITKQDQKWTISNIAEISDNTAKWTQLQALQRTP----WRCFFDFRNKNN
Mflv_1314|M.gilvum_PYR-GCK AMHLSNFTTQVWTFTAGPTSAADANWVKQEAGTDR----RCFVTTRLREN
. . * *
TH_3756|M.thermoresistible__bu IIGDVNTCS-ADPGDSAVRIAQQIGENVDAVW--
Mvan_4738|M.vanbaalenii_PYR-1 IVIDVSTCG-GSS-DSAVRIADQIAARVPGE---
MUL_4150|M.ulcerans_Agy99 VAIDVVTCAYSQSGSVAADVAQQIAAKAAKQ---
Mb1297c|M.bovis_AF2122/97 VVVDVNACG-YQITNQAGQIAAKIVDKVNKE---
Rv1266c|M.tuberculosis_H37Rv VVVDVNACG-YRITNQAGQIAAKIVDKVNKE---
MMAR_4171|M.marinum_M VIVDINSCG-YHITDQGGALADKIVDKIHKETKY
MSMEG_4554|M.smegmatis_MC2_155 LVAEAWACG-EGVEDQASEIVDQIVANIE-----
MAB_2422c|M.abscessus_ATCC_199 VLFGAYLCQYGDGVPGVTTITDRIAAWIPQ----
Mflv_1314|M.gilvum_PYR-GCK VLLQAKVCQSGNGGPAVNVLAGAMQNTLGQ----
: * :. :