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RRAVAIAGIAIMVTGCASTSSAESAEPPTRTMIPRPLVEREIGEVLLSPEEIAALMGVPAMTVIEAQTSL SDHSDIMAPIECLAIDGAGELQVYANSDYRASRDQSLNDGEGWKTYVKQAVVLFPYLEKAGEFFDASVAQ WPACREYTHTQSGSVWNPGEITSADRTLSTVAMQRDAAAPGWGCGRALVHRNNVIVDVNTCSAAPGDSAV RIAHQIADKVDAQW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2235 | - | - | 100% (225) | putative lipoprotein LppH |
| M. gilvum PYR-GCK | Mflv_2675 | - | 4e-21 | 34.64% (179) | hypothetical protein Mflv_2675 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3607 | lppH | 4e-25 | 33.33% (234) | lipoprotein LppH |
| M. tuberculosis H37Rv | Rv3576 | lppH | 1e-24 | 32.91% (234) | lipoprotein LppH |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0358 | - | 5e-10 | 24.53% (212) | membrane protein PknM or lipoprotein LppH |
| M. marinum M | MMAR_5074 | lppH | 1e-25 | 32.20% (236) | lipoprotein LppH |
| M. avium 104 | MAV_2123 | - | 3e-23 | 33.46% (254) | PknM protein |
| M. smegmatis MC2 155 | MSMEG_4554 | - | 1e-16 | 26.34% (224) | serine/threonine-protein kinase PknH, putative |
| M. thermoresistible (build 8) | TH_3756 | - | 2e-74 | 61.47% (218) | PUTATIVE putative conserved lipoprotein LppH |
| M. ulcerans Agy99 | MUL_4150 | lppH | 8e-26 | 32.20% (236) | lipoprotein LppH |
| M. vanbaalenii PYR-1 | Mvan_4460 | - | 1e-94 | 76.21% (227) | putative lipoprotein LppH |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3607|M.bovis_AF2122/97 ----MGKQLAALAALVG-ACMLAAGCTNVVDG----TAVAADKSGPLHQD
Rv3576|M.tuberculosis_H37Rv ----MGKQLAALAALVG-ACMLAAGCTNVVDG----TAVAADKSGPLHQD
MMAR_5074|M.marinum_M ----MRQRVAALAALVGGAGMLVTGCTNIVDG----NAVAADMSGPLNQT
MUL_4150|M.ulcerans_Agy99 ----MRQRVAALAALVGGAGMLVTGCTNIVDG----NAVAADMSGPLNQT
Mflv_2235|M.gilvum_PYR-GCK --------MRR-AVAIAGIAIMVTGCASTSS---AESAEPP--TRTMIPR
Mvan_4460|M.vanbaalenii_PYR-1 --------MRRKTVAILGICILVTGCADTISSADAAGSARP--TRTMIPR
TH_3756|M.thermoresistible__bu ------------------MGVLVAGCGSTGH---AESTTAPSTTKTLIPR
MAV_2123|M.avium_104 --------MRRLAATLAAAGMLVAGCGAGNHG--AASSSTATGSTASPKT
MSMEG_4554|M.smegmatis_MC2_155 MTPGRRWTRLCTAGAAAAVMCLLSGCVTVVGG-----TATRDPAAPPPGA
MAB_0358|M.abscessus_ATCC_1997 ---------MGVASYLCVLAMTVASAGTASAN--------------PDEL
:..
Mb3607|M.bovis_AF2122/97 PIPVSALEGLLLDLSQINAALGATSMKVWFNAKAMWD----WSKSVADKN
Rv3576|M.tuberculosis_H37Rv PIPVSALEGLLLDLSQINAALGATSMKVWFNAKAMWD----WSKSVADKN
MMAR_5074|M.marinum_M PIAVSALDDLLLDVNQIDSALGATSMKVWFNAKAMWD----WSKNISDKN
MUL_4150|M.ulcerans_Agy99 PIAVSALDDLLLDVSQIDSALGATSMKVWFNAKAMWD----WSKNISDKN
Mflv_2235|M.gilvum_PYR-GCK PLVEREIGEVLLSPEEIAALMGVPAMTVIEAQTSLSD----HSDIMAPIE
Mvan_4460|M.vanbaalenii_PYR-1 PLVERELSELLLSPERAAAEMGVPAMTVIESQTTMSD----HSAIMEPPE
TH_3756|M.thermoresistible__bu PLVERELPGLLLSPEQVNAAMGTTDMAIISSQTSLSD----HSNTMAPPE
MAV_2123|M.avium_104 PLARGALPDLMLSPNDIDTALGVTGTTSDPPFTALGEDPVRRTDYTFPAE
MSMEG_4554|M.smegmatis_MC2_155 AVTEVDLDNLLLPVTELGDIVGSDDLTVTVELDQFND----SSAAMDDPD
MAB_0358|M.abscessus_ATCC_1997 PVQTEALSSLMLEPGDVAPVMG-AGMYVAGDWAALVS------DRTDRPE
.: : ::* :* : . :
Mb3607|M.bovis_AF2122/97 CLAIDGPAQEKVYAGTGWTAMR--GQRLDDSIND-SKKRDHYAIQAVVGF
Rv3576|M.tuberculosis_H37Rv CLAIDGPAQEKVYAGTGWTAMR--GQRLDDSIDD-SKKRDHYAIQAVVGF
MMAR_5074|M.marinum_M CLAVDGPAQDEVYAGTGWTAMR--GQRMDDSVDD-SKRRKHYAIQAVVAF
MUL_4150|M.ulcerans_Agy99 CLAVDGPAQDEVYAGTGWTAMR--GQRMDDSVDD-SKRRKHYAIQAVVAF
Mflv_2235|M.gilvum_PYR-GCK CLAIDGAGELQVYANSD------YRASRDQSLND-GEGWKTYVKQAVVLF
Mvan_4460|M.vanbaalenii_PYR-1 CLAIDGAAELSVYADTG------YRAERDQSLND-GEGWKHYLKQSVVLF
TH_3756|M.thermoresistible__bu CLALDGAGEADVYADSG------YRAARDHSLNN-GDNFTHYAKQAVVLF
MAV_2123|M.avium_104 CKYTTHAGLASEYAGSGSTAVYGYHDLAPTPAGA-NQLESPEVYQFVVLF
MSMEG_4554|M.smegmatis_MC2_155 CLAAAFGAQERVYAGTG------WTAVRDQIVREPGSFSPHWIEQVVVLF
MAB_0358|M.abscessus_ATCC_1997 CGSVVLASGAS-YESSN------YLSGRYRSLID-SPNWTRLVDQSMVIF
* . * .:. . * :* *
Mb3607|M.bovis_AF2122/97 PTAHDAEEFYSSSVQSWSSCSNRRFVEVTPG-QDDAAWTVADVVNDNGML
Rv3576|M.tuberculosis_H37Rv PTAHDAEEFYSSSVQSWSSCSNRRFVEVTPG-QDDAAWTVADVVNDNGML
MMAR_5074|M.marinum_M PSAHDASAFYNSSVRSWGNCSNRRFTDVSTD-QPDTIWTVSDVVNDNGML
MUL_4150|M.ulcerans_Agy99 PSAHDASAFYNSSVRSWGNCSNRRFTDVSTD-QPDTIWTVSDVVNDNGML
Mflv_2235|M.gilvum_PYR-GCK PYLEKAGEFFDASVAQWPACREYTHTQSGS------VWNPGEITSADRTL
Mvan_4460|M.vanbaalenii_PYR-1 PYQEKAGEFFDASVRQWPACHRYTHTQSGS------QWTVGEITVDGGML
TH_3756|M.thermoresistible__bu PLAETARAFFEASAEQWPACHEYRHTQSGT------KWYVAELTRDGDIL
MAV_2123|M.avium_104 PSPEQASAFLSASSARWPACANRQDTVPADGTNPELRWKVGPVTNANGML
MSMEG_4554|M.smegmatis_MC2_155 TSDLHARDFFDQSRETWRGCVGTLTTYDIDQ--MPLEWVVGEVTAEESTI
MAB_0358|M.abscessus_ATCC_1997 PEWSDATDFALAEADRWRACENQRVTSLLPQPDGSTRREWVQLRKIVQVQ
. * * . * * . :
Mb3607|M.bovis_AF2122/97 S-----SSQVQEGGDGWTCQRALTARNNVTIDIVTCAYSQPDLVAIGIAN
Rv3576|M.tuberculosis_H37Rv S-----SSQVQEGGDGWTCQRALTARNNVTIDIVTCAYSQPDLVAIGIAN
MMAR_5074|M.marinum_M S-----TSQVQEAGDGWTCQRALTVRNNVAIDVVTCAYSQSGSVAADVAQ
MUL_4150|M.ulcerans_Agy99 S-----TSQVQEAGDGWTCQRALTVRNNVAIDVVTCAYSQSGSVAADVAQ
Mflv_2235|M.gilvum_PYR-GCK S---TVAMQRDAAAPGWGCGRALVHRNNVIVDVNTCSAA-PGDSAVRIAH
Mvan_4460|M.vanbaalenii_PYR-1 S---TVAMQQDAAAPGWGCGRALARRNNVIVDVNTCSAE-PGDSAVRIAR
TH_3756|M.thermoresistible__bu K---AITVQRDAGHPGWGCGRALVLRNNIIGDVNTCSAD-PGDSAVRIAQ
MAV_2123|M.avium_104 SSQVTVTVNGNGVNVTMPCQRALTARNNIVIDVDACRKD-VGDLGIDIAK
MSMEG_4554|M.smegmatis_MC2_155 S-----QLSVPETAVRGGCHHALSVAANLVAEAWACGEG-VEDQASEIVD
MAB_0358|M.abscessus_ATCC_1997 EVLVVGYTWPTDFGGVIYCQHALAPLRNVAIDVRACAER-DGSRALDLIL
. * :** *: : :* . :
Mb3607|M.bovis_AF2122/97 QIAAKVAKQ-
Rv3576|M.tuberculosis_H37Rv QIAAKVAKQ-
MMAR_5074|M.marinum_M QIAAKAAKQ-
MUL_4150|M.ulcerans_Agy99 QIAAKAAKQ-
Mflv_2235|M.gilvum_PYR-GCK QIADKVDAQW
Mvan_4460|M.vanbaalenii_PYR-1 QITANVDAQW
TH_3756|M.thermoresistible__bu QIGENVDAVW
MAV_2123|M.avium_104 QIAGKVDKQ-
MSMEG_4554|M.smegmatis_MC2_155 QIVANIE---
MAB_0358|M.abscessus_ATCC_1997 GLLPRVARA-
: .