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VRQRVAALAALVGGAGMLVTGCTNIVDGNAVAADMSGPLNQTPIAVSALDDLLLDVSQIDSALGATSMKV WFNAKAMWDWSKNISDKNCLAVDGPAQDEVYAGTGWTAMRGQRMDDSVDDSKRRKHYAIQAVVAFPSAHD ASAFYNSSVRSWGNCSNRRFTDVSTDQPDTIWTVSDVVNDNGMLSTSQVQEAGDGWTCQRALTVRNNVAI DVVTCAYSQSGSVAADVAQQIAAKAAKQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4150 | lppH | - | 100% (238) | lipoprotein LppH |
| M. ulcerans Agy99 | MUL_4151 | - | 2e-19 | 26.01% (223) | lipoprotein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3607 | lppH | 1e-104 | 74.79% (238) | lipoprotein LppH |
| M. gilvum PYR-GCK | Mflv_2675 | - | 3e-28 | 33.03% (218) | hypothetical protein Mflv_2675 |
| M. tuberculosis H37Rv | Rv3576 | lppH | 1e-104 | 75.21% (238) | lipoprotein LppH |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0358 | - | 1e-09 | 26.48% (219) | membrane protein PknM or lipoprotein LppH |
| M. marinum M | MMAR_5074 | lppH | 1e-136 | 99.58% (238) | lipoprotein LppH |
| M. avium 104 | MAV_2123 | - | 1e-25 | 36.14% (249) | PknM protein |
| M. smegmatis MC2 155 | MSMEG_4554 | - | 7e-21 | 30.56% (216) | serine/threonine-protein kinase PknH, putative |
| M. thermoresistible (build 8) | TH_3756 | - | 3e-29 | 36.07% (219) | PUTATIVE putative conserved lipoprotein LppH |
| M. vanbaalenii PYR-1 | Mvan_4460 | - | 7e-32 | 37.34% (233) | putative lipoprotein LppH |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2675|M.gilvum_PYR-GCK MT---------------ALMLPMTACVETVDGTALRGHGAGLTDVAPLDE
MSMEG_4554|M.smegmatis_MC2_155 MTPGRRWTRLCTAGAAAAVMCLLSGCVTVVGGTATRDP-AAPPPGAAVTE
MUL_4150|M.ulcerans_Agy99 --MRQRVAALAALVGGAGMLVTGCTNIVDGNAVAADMSG--PLNQTPIAV
MMAR_5074|M.marinum_M --MRQRVAALAALVGGAGMLVTGCTNIVDGNAVAADMSG--PLNQTPIAV
Mb3607|M.bovis_AF2122/97 --MGKQLAALAALVG-ACMLAAGCTNVVDGTAVAADKSG--PLHQDPIPV
Rv3576|M.tuberculosis_H37Rv --MGKQLAALAALVG-ACMLAAGCTNVVDGTAVAADKSG--PLHQDPIPV
TH_3756|M.thermoresistible__bu ----------------MGVLVAGCGSTG-HAESTTAPSTTKTLIPRPLVE
Mvan_4460|M.vanbaalenii_PYR-1 ------MRRKTVAILGICILVTGCADTISSADAAGSARPTRTMIPRPLVE
MAV_2123|M.avium_104 ------MRRLAATLAAAGMLVAGCGAGNHGAASSSTATGSTASPKTPLAR
MAB_0358|M.abscessus_ATCC_1997 ----------------MGVASYLCVLAMTVASAGTASAN---PDELPVQT
: .:
Mflv_2675|M.gilvum_PYR-GCK SRLDSVLVGIDEINSIMGATGMEVTGELDEMSD----HSADVSDPDCLGA
MSMEG_4554|M.smegmatis_MC2_155 VDLDNLLLPVTELGDIVGSDDLTVTVELDQFND----SSAAMDDPDCLAA
MUL_4150|M.ulcerans_Agy99 SALDDLLLDVSQIDSALGATSMKVWFNAKAMWD----WSKNISDKNCLAV
MMAR_5074|M.marinum_M SALDDLLLDVNQIDSALGATSMKVWFNAKAMWD----WSKNISDKNCLAV
Mb3607|M.bovis_AF2122/97 SALEGLLLDLSQINAALGATSMKVWFNAKAMWD----WSKSVADKNCLAI
Rv3576|M.tuberculosis_H37Rv SALEGLLLDLSQINAALGATSMKVWFNAKAMWD----WSKSVADKNCLAI
TH_3756|M.thermoresistible__bu RELPGLLLSPEQVNAAMGTTDMAIISSQTSLSD----HSNTMAPPECLAL
Mvan_4460|M.vanbaalenii_PYR-1 RELSELLLSPERAAAEMGVPAMTVIESQTTMSD----HSAIMEPPECLAI
MAV_2123|M.avium_104 GALPDLMLSPNDIDTALGVTGTTSDPPFTALGEDPVRRTDYTFPAECKYT
MAB_0358|M.abscessus_ATCC_1997 EALSSLMLEPGDVAPVMG-AGMYVAGDWAALVS------DRTDRPECGSV
* ::: :* : . :*
Mflv_2675|M.gilvum_PYR-GCK VYGAEAPVYEGTDWTAVR-----DQVAREPGAGNDHWVEQAVVLYPEERN
MSMEG_4554|M.smegmatis_MC2_155 AFGAQERVYAGTGWTAVR-----DQIVREPGSFSPHWIEQVVVLFTSDLH
MUL_4150|M.ulcerans_Agy99 DGPAQDEVYAGTGWTAMR--GQRMDDSVDDSKRRKHYAIQAVVAFPSAHD
MMAR_5074|M.marinum_M DGPAQDEVYAGTGWTAMR--GQRMDDSVDDSKRRKHYAIQAVVAFPSAHD
Mb3607|M.bovis_AF2122/97 DGPAQEKVYAGTGWTAMR--GQRLDDSINDSKKRDHYAIQAVVGFPTAHD
Rv3576|M.tuberculosis_H37Rv DGPAQEKVYAGTGWTAMR--GQRLDDSIDDSKKRDHYAIQAVVGFPTAHD
TH_3756|M.thermoresistible__bu DGAGEADVYADSG------YRAARDHSLNNGDNFTHYAKQAVVLFPLAET
Mvan_4460|M.vanbaalenii_PYR-1 DGAAELSVYADTG------YRAERDQSLNDGEGWKHYLKQSVVLFPYQEK
MAV_2123|M.avium_104 THAGLASEYAGSGSTAVYGYHDLAPTPAGANQLESPEVYQFVVLFPSPEQ
MAB_0358|M.abscessus_ATCC_1997 VLASGAS-YESSNYLSGR------YRSLIDSPNWTRLVDQSMVIFPEWSD
. * .:. . * :* :.
Mflv_2675|M.gilvum_PYR-GCK ARDFLESSQAVWRDCAN----NALGV--GDYLWELGAVEAADLMLT----
MSMEG_4554|M.smegmatis_MC2_155 ARDFFDQSRETWRGCVGTLTTYDIDQ--MPLEWVVGEVTAEESTIS----
MUL_4150|M.ulcerans_Agy99 ASAFYNSSVRSWGNCSNRRFTDVSTD-QPDTIWTVSDVVNDNGMLS----
MMAR_5074|M.marinum_M ASAFYNSSVRSWGNCSNRRFTDVSTD-QPDTIWTVSDVVNDNGMLS----
Mb3607|M.bovis_AF2122/97 AEEFYSSSVQSWSSCSNRRFVEVTPG-QDDAAWTVADVVNDNGMLS----
Rv3576|M.tuberculosis_H37Rv AEEFYSSSVQSWSSCSNRRFVEVTPG-QDDAAWTVADVVNDNGMLS----
TH_3756|M.thermoresistible__bu ARAFFEASAEQWPACHEYRHTQSGT------KWYVAELTRDGDILK---A
Mvan_4460|M.vanbaalenii_PYR-1 AGEFFDASVRQWPACHRYTHTQSGS------QWTVGEITVDGGMLS---T
MAV_2123|M.avium_104 ASAFLSASSARWPACANRQDTVPADGTNPELRWKVGPVTNANGMLSSQVT
MAB_0358|M.abscessus_ATCC_1997 ATDFALAEADRWRACENQRVTSLLPQPDGSTRREWVQLRKIVQVQEVLVV
* * . * * :
Mflv_2675|M.gilvum_PYR-GCK -QVTTQEGADGWSCQHALSLVSNVTVEAWACGYD-ITDEAARIADAMIRN
MSMEG_4554|M.smegmatis_MC2_155 -QLSVPETAVRGGCHHALSVAANLVAEAWACGEG-VEDQASEIVDQIVAN
MUL_4150|M.ulcerans_Agy99 -TSQVQEAGDGWTCQRALTVRNNVAIDVVTCAYSQSGSVAADVAQQIAAK
MMAR_5074|M.marinum_M -TSQVQEAGDGWTCQRALTVRNNVAIDVVTCAYSQSGSVAADVAQQIAAK
Mb3607|M.bovis_AF2122/97 -SSQVQEGGDGWTCQRALTARNNVTIDIVTCAYSQPDLVAIGIANQIAAK
Rv3576|M.tuberculosis_H37Rv -SSQVQEGGDGWTCQRALTARNNVTIDIVTCAYSQPDLVAIGIANQIAAK
TH_3756|M.thermoresistible__bu ITVQRDAGHPGWGCGRALVLRNNIIGDVNTCSAD-PGDSAVRIAQQIGEN
Mvan_4460|M.vanbaalenii_PYR-1 VAMQQDAAAPGWGCGRALARRNNVIVDVNTCSAE-PGDSAVRIARQITAN
MAV_2123|M.avium_104 VTVNGNGVNVTMPCQRALTARNNIVIDVDACRKD-VGDLGIDIAKQIAGK
MAB_0358|M.abscessus_ATCC_1997 GYTWPTDFGGVIYCQHALAPLRNVAIDVRACAER-DGSRALDLILGLLPR
* :** *: : :* . : : .
Mflv_2675|M.gilvum_PYR-GCK AAG--
MSMEG_4554|M.smegmatis_MC2_155 IE---
MUL_4150|M.ulcerans_Agy99 AAKQ-
MMAR_5074|M.marinum_M AAKQ-
Mb3607|M.bovis_AF2122/97 VAKQ-
Rv3576|M.tuberculosis_H37Rv VAKQ-
TH_3756|M.thermoresistible__bu VDAVW
Mvan_4460|M.vanbaalenii_PYR-1 VDAQW
MAV_2123|M.avium_104 VDKQ-
MAB_0358|M.abscessus_ATCC_1997 VARA-