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VPEVDVGQRYTEVADLYIRMFGAVDRVAPQDLSFLERNLGDSDGTVLDAGCGPGHLAAYLTGLGLTVQGV DLVPEFIGNARANWPGVDFAVGSVHTLDMPDRSLGAILAWFSLIHCEPAELTDVLTEFRRVVRRGGMLVV GFFEGACVERFDHKVAPAYRWPVDEMSRMLSAAGFAETERCRRSGTAQTRPYAALAARAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4619 | - | - | 100% (200) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_1534 | - | 8e-12 | 33.58% (137) | methyltransferase type 12 |
| M. vanbaalenii PYR-1 | Mvan_4620 | - | 8e-09 | 29.20% (137) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3374 | - | 4e-07 | 34.41% (93) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_4890 | - | 2e-11 | 35.56% (135) | methyltransferase type 12 |
| M. tuberculosis H37Rv | Rv3342 | - | 4e-07 | 34.41% (93) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_01713 | - | 4e-05 | 25.00% (140) | hypothetical protein MLBr_01713 |
| M. abscessus ATCC 19977 | MAB_2548c | - | 6e-09 | 32.38% (105) | hypothetical protein MAB_2548c |
| M. marinum M | MMAR_1164 | - | 5e-11 | 32.85% (137) | methyltransferase |
| M. avium 104 | MAV_4332 | - | 3e-10 | 32.84% (134) | SAM-dependent methyltransferases |
| M. smegmatis MC2 155 | MSMEG_6572 | - | 8e-18 | 31.55% (206) | methyltransferase |
| M. thermoresistible (build 8) | TH_1247 | - | 2e-13 | 33.33% (150) | SAM-dependent methyltransferase |
| M. ulcerans Agy99 | MUL_2851 | - | 4e-11 | 32.85% (137) | methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1164|M.marinum_M -----------MVEQSIWMQKVAADPGHSRWYIERFRAMARAGEDLVGEA
MUL_2851|M.ulcerans_Agy99 -----------MVEQSIWMQKVAADPGHSRWYIERFRAMARAGEDLVGEA
TH_1247|M.thermoresistible__bu -----------MVEKSLWMRKVEADPGHSQWYIERFRAMARAGEDLVGEA
MAV_4332|M.avium_104 -----------MVEQSIWMQKVAADPGHSHWYIERFRAMARAGDDLAGEA
Mflv_4890|M.gilvum_PYR-GCK -----------MAETSLWMQKVAADPGHSRWYIERFRAMARAGDDLFGEA
MAB_2548c|M.abscessus_ATCC_199 -----------MVEQSLWMQKVAADPNHSQWYIDRFRSMARDGADLAGEA
Mb3374|M.bovis_AF2122/97 --------------------MTCSRRDMSLSFGSAVGAYERGRPSYPPEA
Rv3342|M.tuberculosis_H37Rv --------------------MTCSRRDMSLSFGSAVGAYERGRPSYPPEA
Mvan_4619|M.vanbaalenii_PYR-1 ------------------MPEVDVGQRYTEVADLYIRMFGAVDRVAPQDL
MSMEG_6572|M.smegmatis_MC2_155 ---MVGARAALGGFRLRRPTVVGVYDQYDVIADDYAQHFPDDFASRPFDR
MLBr_01713|M.leprae_Br4923 MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQ
. .
MMAR_1164|M.marinum_M RLVDSIAP----RGAH-ILDAGCGPGRLGRHLAAAGHRVVGVDVDPALIE
MUL_2851|M.ulcerans_Agy99 RLVDSIAP----RGAH-ILDAGCGPGRLGRHLAAAGHRVVGVDVDPALIE
TH_1247|M.thermoresistible__bu RLVDAMAP----RNAH-ILDAGCGPGRLGGYLSAAGHRVVGVDVDPALIE
MAV_4332|M.avium_104 RFVDAMAP----RGAR-ILDAGCGPGRLGSYLAAAGHQVVGVDVDPALIE
Mflv_4890|M.gilvum_PYR-GCK RLIDAMVP----RGAR-ILDAGCGPGRLGGYLAAAGHHVVGVDVDPVLID
MAB_2548c|M.abscessus_ATCC_199 RLVDALVP----RGAR-ILDAGCGAGRVGGFLAAAGHHVVGVDVDPALIE
Mb3374|M.bovis_AF2122/97 --IDWLLP----AAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLD
Rv3342|M.tuberculosis_H37Rv --IDWLLP----AAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLD
Mvan_4619|M.vanbaalenii_PYR-1 SFLERNLG----DSDGTVLDAGCGPGHLAAYLTGLGLTVQGVDLVPEFIG
MSMEG_6572|M.smegmatis_MC2_155 ALVHVFAGLVQQSGGGNVLDVGCGPGQATAELGAAGLRTHAIDGSPAMVS
MLBr_01713|M.leprae_Br4923 VVYQWLAQR---CTGCEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVA
. :*: *.* * : . . .:* :
MMAR_1164|M.marinum_M AAEQDYPGPQWLVGDLAELDL------------------PARGIAEPFDV
MUL_2851|M.ulcerans_Agy99 AAEQDYPGPQWLVGDLAELDL------------------PARGIAEPFDV
TH_1247|M.thermoresistible__bu AAEQDYPGPQYLVGDLAELDL------------------PARGIPDPFDV
MAV_4332|M.avium_104 AAEHDHPGPRWLVGDLAELDL------------------PARGITDPFDV
Mflv_4890|M.gilvum_PYR-GCK AAEKDHPGATWLVGDLAELDL------------------PARGIAEPFDV
MAB_2548c|M.abscessus_ATCC_199 AAEHDHPGPRWLVGDLAELDL------------------PSRGISEPFDV
Mb3374|M.bovis_AF2122/97 VLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARV
Rv3342|M.tuberculosis_H37Rv VLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARV
Mvan_4619|M.vanbaalenii_PYR-1 NARANWPGVDFAVGSVHTLDM------------------PDRSLGAILAW
MSMEG_6572|M.smegmatis_MC2_155 IARRRYPHARYQVADMASLPY------------------QDAAFGGLCAW
MLBr_01713|M.leprae_Br4923 HVRSRYPRVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECAR
. * . : :
MMAR_1164|M.marinum_M IVSAGNV-MTFLAP---------------STRARVLGRLRAHLCSDGRAV
MUL_2851|M.ulcerans_Agy99 IVSAGNV-MTFLAP---------------STRARVLGRLRAHLCSDGRAV
TH_1247|M.thermoresistible__bu IVMAGNV-MAFLAP---------------STRTTVLSRLRAHLAEDGRAA
MAV_4332|M.avium_104 IVSAGNV-MTFLAP---------------STRVLVLSRLRAHLAADGRAA
Mflv_4890|M.gilvum_PYR-GCK IVSAGNV-MTFLAP---------------STRGEVLRRLRTHLAAEGRAV
MAB_2548c|M.abscessus_ATCC_199 IVSAGNV-MAFLAP---------------STRRQVLRRLRSHLADPGRAV
Mb3374|M.bovis_AF2122/97 LRPGGRLGLVWNTR---------------DERLGWVRELGEIIGRDGDPV
Rv3342|M.tuberculosis_H37Rv LRPGGRLGLVWNTR---------------DERLGWVRELGEIIGRDGDPV
Mvan_4619|M.vanbaalenii_PYR-1 FS------LIHCEP---------------AELTDVLTEFRRVVRRGGMLV
MSMEG_6572|M.smegmatis_MC2_155 YS------IIHTPA---------------DRLAGLFAEFSRVLADPGWLL
MLBr_01713|M.leprae_Br4923 VLRPSGLLMVSTPNRITFSPGRDTSINPFHTRELNADELTQLLITADFSE
: .: : .
MMAR_1164|M.marinum_M IG-------FGAGR--DYAFAD---FLDDAQAAGLVP-------------
MUL_2851|M.ulcerans_Agy99 IG-------FGAGR--DYAFAD---FLDDAQAAGLVP-------------
TH_1247|M.thermoresistible__bu IG-------FGAGR--DYDFDE---FLADAATAGLTP-------------
MAV_4332|M.avium_104 IG-------FGAYR--EYEFTD---FLNDAADAGFAP-------------
Mflv_4890|M.gilvum_PYR-GCK IG-------FGADR--DYDFAE---FLDDAAGAGFVP-------------
MAB_2548c|M.abscessus_ATCC_199 IG-------FGAGR--DYEFSE---FLSDADAAGLVP-------------
Mb3374|M.bovis_AF2122/97 RDRVTLPEPFTTVQRHQVEWTN---YLTPQALIDLVASRSYCITSPAQVR
Rv3342|M.tuberculosis_H37Rv RDRVTLPEPFTTVQRHQVEWTN---YLTPQALIDLVASRSYCITSPAQVR
Mvan_4619|M.vanbaalenii_PYR-1 VG------FFEGACVERFDHKV---APAYRWPVDEMSR-----------M
MSMEG_6572|M.smegmatis_MC2_155 LG-------FQTDAP-PLVFDE---AFGHKVDMTFLRHN----VTAVHEA
MLBr_01713|M.leprae_Br4923 VAMYG---LFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVADVAA
*
MMAR_1164|M.marinum_M ----DLLLSTWDLRPFTDDCD-----FLVALLRPA----
MUL_2851|M.ulcerans_Agy99 ----DLLLSTWDLRPFTDDCD-----FLVALLRPA----
TH_1247|M.thermoresistible__bu ----DLLLSTWDLRPFTEDSE-----FLVALLRRA----
MAV_4332|M.avium_104 ----DLLLSSWDLRPFTEDSD-----FLVAVLRPA----
Mflv_4890|M.gilvum_PYR-GCK ----DLLLSTWDLRPWREDSG-----FLVAVLRRM----
MAB_2548c|M.abscessus_ATCC_199 ----DLLLSTWDLRPFTDKSD-----FLVALLRRDDAPS
Mb3374|M.bovis_AF2122/97 TKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA--
Rv3342|M.tuberculosis_H37Rv TKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA--
Mvan_4619|M.vanbaalenii_PYR-1 LSAAGFAETERCRRSGTAQTR----PYAALAARAA----
MSMEG_6572|M.smegmatis_MC2_155 LLAAGFTVYATSKRERLQHLSETAAQAFVIAHRGPLH--
MLBr_01713|M.leprae_Br4923 VTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR---
. .