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VVGARAALGGFRLRRPTVVGVYDQYDVIADDYAQHFPDDFASRPFDRALVHVFAGLVQQSGGGNVLDVGC GPGQATAELGAAGLRTHAIDGSPAMVSIARRRYPHARYQVADMASLPYQDAAFGGLCAWYSIIHTPADRL AGLFAEFSRVLADPGWLLLGFQTDAPPLVFDEAFGHKVDMTFLRHNVTAVHEALLAAGFTVYATSKRERL QHLSETAAQAFVIAHRGPLH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6572 | - | - | 100% (230) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_3286 | - | 8e-14 | 34.67% (150) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_3430 | - | 4e-07 | 30.84% (107) | SAM-dependent methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0575c | - | 4e-06 | 31.93% (119) | benzoquinone methyltransferase |
| M. gilvum PYR-GCK | Mflv_3090 | - | 1e-09 | 32.20% (118) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0560c | - | 4e-06 | 31.93% (119) | benzoquinone methyltransferase |
| M. leprae Br4923 | MLBr_01713 | - | 5e-07 | 30.56% (108) | hypothetical protein MLBr_01713 |
| M. abscessus ATCC 19977 | MAB_2548c | - | 8e-09 | 31.51% (146) | hypothetical protein MAB_2548c |
| M. marinum M | MMAR_1164 | - | 4e-08 | 41.82% (55) | methyltransferase |
| M. avium 104 | MAV_4332 | - | 2e-07 | 40.00% (55) | SAM-dependent methyltransferases |
| M. thermoresistible (build 8) | TH_1247 | - | 4e-08 | 43.40% (53) | SAM-dependent methyltransferase |
| M. ulcerans Agy99 | MUL_2851 | - | 3e-08 | 41.82% (55) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4619 | - | 9e-18 | 31.55% (206) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1164|M.marinum_M MVEQSIWMQKVAADPGHSRWYIERFRAMARAGEDLVGEAR----------
MUL_2851|M.ulcerans_Agy99 MVEQSIWMQKVAADPGHSRWYIERFRAMARAGEDLVGEAR----------
TH_1247|M.thermoresistible__bu MVEKSLWMRKVEADPGHSQWYIERFRAMARAGEDLVGEAR----------
MAV_4332|M.avium_104 MVEQSIWMQKVAADPGHSHWYIERFRAMARAGDDLAGEAR----------
MAB_2548c|M.abscessus_ATCC_199 MVEQSLWMQKVAADPNHSQWYIDRFRSMARDGADLAGEAR----------
Mflv_3090|M.gilvum_PYR-GCK --MSTRWQQ---SDRPRGEDYDARWKRLAASGASVHGEAD----------
Mb0575c|M.bovis_AF2122/97 MSTVLTYIRAVDIYEHMTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQ
Rv0560c|M.tuberculosis_H37Rv MSTVLTYIRAVDIYEHMTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQ
Mvan_4619|M.vanbaalenii_PYR-1 -------MPEVDVGQRYTEVADLYIRMFGAVDRVAPQDLS----------
MSMEG_6572|M.smegmatis_MC2_155 MVGARAALGGFRLRRPTVVGVYDQYDVIADDYAQHFPDDFASR-PFDRAL
MLBr_01713|M.leprae_Br4923 MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIEN-YWFRRH
:
MMAR_1164|M.marinum_M --LVDSIAPRG--AHILDAGCGPGRLGRHLAAAGHRVVGVDVDPALIEAA
MUL_2851|M.ulcerans_Agy99 --LVDSIAPRG--AHILDAGCGPGRLGRHLAAAGHRVVGVDVDPALIEAA
TH_1247|M.thermoresistible__bu --LVDAMAPRN--AHILDAGCGPGRLGGYLSAAGHRVVGVDVDPALIEAA
MAV_4332|M.avium_104 --FVDAMAPRG--ARILDAGCGPGRLGSYLAAAGHQVVGVDVDPALIEAA
MAB_2548c|M.abscessus_ATCC_199 --LVDALVPRG--ARILDAGCGAGRVGGFLAAAGHHVVGVDVDPALIEAA
Mflv_3090|M.gilvum_PYR-GCK --LIEALLREGGGTRVLDAGCGTGRVAIELAARGFDVVGLDADPTMLETA
Mb0575c|M.bovis_AF2122/97 PELAALIVQGKFRGDVLDVGCGEAAISLALAERGHTTVGLDLSPAAVELA
Rv0560c|M.tuberculosis_H37Rv PELAALIVQGKFRGDVLDVGCGEAAISLALAERGHTTVGLDLSPAAVELA
Mvan_4619|M.vanbaalenii_PYR-1 --FLERNLGDS-DGTVLDAGCGPGHLAAYLTGLGLTVQGVDLVPEFIGNA
MSMEG_6572|M.smegmatis_MC2_155 VHVFAGLVQQSGGGNVLDVGCGPGQATAELGAAGLRTHAIDGSPAMVSIA
MLBr_01713|M.leprae_Br4923 QVVYQWLAQRCTGCEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVAHV
. :*:.*** . : . . .:* : .
MMAR_1164|M.marinum_M EQDYPGPQWLVGDLAELDLP-------------------------ARGIA
MUL_2851|M.ulcerans_Agy99 EQDYPGPQWLVGDLAELDLP-------------------------ARGIA
TH_1247|M.thermoresistible__bu EQDYPGPQYLVGDLAELDLP-------------------------ARGIP
MAV_4332|M.avium_104 EHDHPGPRWLVGDLAELDLP-------------------------ARGIT
MAB_2548c|M.abscessus_ATCC_199 EHDHPGPRWLVGDLAELDLP-------------------------SRGIS
Mflv_3090|M.gilvum_PYR-GCK RAKAPRLRWIEADLVDTDD----------------------------HLD
Mb0575c|M.bovis_AF2122/97 RHEAAKRGLANASFEVADASS------------------------FTGYD
Rv0560c|M.tuberculosis_H37Rv RHEAAKRGLANASFEVADASS------------------------FTGYD
Mvan_4619|M.vanbaalenii_PYR-1 RANWPGVDFAVGSVHTLDMP------------------------------
MSMEG_6572|M.smegmatis_MC2_155 RRRYPHARYQVADMASLPYQ------------------------------
MLBr_01713|M.leprae_Br4923 RSRYPRVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECARVL
. . ...
MMAR_1164|M.marinum_M EPFDVIVSAGNVMTFLAPSTRARVLGRLRAHLCSDGR----AVIGFG---
MUL_2851|M.ulcerans_Agy99 EPFDVIVSAGNVMTFLAPSTRARVLGRLRAHLCSDGR----AVIGFG---
TH_1247|M.thermoresistible__bu DPFDVIVMAGNVMAFLAPSTRTTVLSRLRAHLAEDGR----AAIGFG---
MAV_4332|M.avium_104 DPFDVIVSAGNVMTFLAPSTRVLVLSRLRAHLAADGR----AAIGFG---
MAB_2548c|M.abscessus_ATCC_199 EPFDVIVSAGNVMAFLAPSTRRQVLRRLRSHLADPGR----AVIGFG---
Mflv_3090|M.gilvum_PYR-GCK ETFDVVALPGNVMIFLDRGTEAAVVAALARRLAPGGL----LVAGFQ---
Mb0575c|M.bovis_AF2122/97 GRFDTIVDSTLFHSMPVESREGYLQSIVRAAAPGASY----FVLVFDRAA
Rv0560c|M.tuberculosis_H37Rv GRFDTIVDSTLFHSMPVESREGYLQSIVRAAAPGASY----FVLVFDRAA
Mvan_4619|M.vanbaalenii_PYR-1 DRSLGAILAWFSLIHCEPAELTDVLTEFRRVVRRGGM----LVVGFFEGA
MSMEG_6572|M.smegmatis_MC2_155 DAAFGGLCAWYSIIHTPADRLAGLFAEFSRVLADPGW----LLLGFQTDA
MLBr_01713|M.leprae_Br4923 RPSGLLMVSTPNRITFSPGRDTSINPFHTRELNADELTQLLITADFSEVA
. : *
MMAR_1164|M.marinum_M ------AGR-DYAFADFLDD-AQAAGLVPDLLLSTWDLRPFTDDCDFLVA
MUL_2851|M.ulcerans_Agy99 ------AGR-DYAFADFLDD-AQAAGLVPDLLLSTWDLRPFTDDCDFLVA
TH_1247|M.thermoresistible__bu ------AGR-DYDFDEFLAD-AATAGLTPDLLLSTWDLRPFTEDSEFLVA
MAV_4332|M.avium_104 ------AYR-EYEFTDFLND-AADAGFAPDLLLSSWDLRPFTEDSDFLVA
MAB_2548c|M.abscessus_ATCC_199 ------AGR-DYEFSEFLSD-ADAAGLVPDLLLSTWDLRPFTDKSDFLVA
Mflv_3090|M.gilvum_PYR-GCK ------LGTGRLTLDRYDEI-TATAALELVDRWATWDRQPYD-GGDYAVS
Mb0575c|M.bovis_AF2122/97 ----IPEGPINAVTEDELRA-AVSKYWIIDEIKPARLYARFPAGFAGMPA
Rv0560c|M.tuberculosis_H37Rv ----IPEGPINAVTEDELRA-AVSKYWIIDEIKPARLYARFPAGFAGMPA
Mvan_4619|M.vanbaalenii_PYR-1 ----CVERFDHKVAPAYRWP-VDEMSRMLSAAGFAETERCRRSGTAQTRP
MSMEG_6572|M.smegmatis_MC2_155 PPLVFDEAFGHKVDMTFLRHNVTAVHEALLAAGFTVYATSKRERLQHLSE
MLBr_01713|M.leprae_Br4923 MYG-LFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVADVAAVTAA
.
MMAR_1164|M.marinum_M LLRPA---------------------------
MUL_2851|M.ulcerans_Agy99 LLRPA---------------------------
TH_1247|M.thermoresistible__bu LLRRA---------------------------
MAV_4332|M.avium_104 VLRPA---------------------------
MAB_2548c|M.abscessus_ATCC_199 LLRRDDAPS-----------------------
Mflv_3090|M.gilvum_PYR-GCK LHRLT---------------------------
Mb0575c|M.bovis_AF2122/97 LLDIREEPNGLQSIGGWLLSAHLG--------
Rv0560c|M.tuberculosis_H37Rv LLDIREEPNGLQSIGGWLLSAHLG--------
Mvan_4619|M.vanbaalenii_PYR-1 YAALAARAA-----------------------
MSMEG_6572|M.smegmatis_MC2_155 TAAQAFVIAHRGPLH-----------------
MLBr_01713|M.leprae_Br4923 DFDIIEASAGPEASDGRDVDESLDLIAIAVRR