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VEQSIWMQKVAADPGHSHWYIERFRAMARAGDDLAGEARFVDAMAPRGARILDAGCGPGRLGSYLAAAGH QVVGVDVDPALIEAAEHDHPGPRWLVGDLAELDLPARGITDPFDVIVSAGNVMTFLAPSTRVLVLSRLRA HLAADGRAAIGFGAYREYEFTDFLNDAADAGFAPDLLLSSWDLRPFTEDSDFLVAVLRPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4332 | - | - | 100% (201) | SAM-dependent methyltransferases |
| M. avium 104 | MAV_4317 | - | 3e-05 | 35.00% (80) | putative methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0092 | - | 2e-07 | 34.51% (113) | methyltransferase/methylase |
| M. gilvum PYR-GCK | Mflv_4890 | - | 2e-93 | 82.41% (199) | methyltransferase type 12 |
| M. tuberculosis H37Rv | Rv0089 | - | 2e-07 | 34.51% (113) | methyltransferase/methylase |
| M. leprae Br4923 | MLBr_00130 | - | 2e-05 | 33.33% (129) | hypothetical protein MLBr_00130 |
| M. abscessus ATCC 19977 | MAB_2548c | - | 8e-92 | 80.40% (199) | hypothetical protein MAB_2548c |
| M. marinum M | MMAR_1164 | - | 4e-96 | 83.08% (201) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_3430 | - | 2e-92 | 80.10% (201) | SAM-dependent methyltransferase |
| M. thermoresistible (build 8) | TH_1247 | - | 6e-94 | 82.09% (201) | SAM-dependent methyltransferase |
| M. ulcerans Agy99 | MUL_2851 | - | 3e-96 | 83.08% (201) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1534 | - | 1e-100 | 87.06% (201) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4332|M.avium_104 -------------------MVEQSIWMQKVAADPG-----HSHWYIER--
Mvan_1534|M.vanbaalenii_PYR-1 -------------------MVETSIWMQKVAADPG-----HSRWYIER--
MSMEG_3430|M.smegmatis_MC2_155 -------------------MVEQSLWMQKVAADPG-----HSQWYIER--
TH_1247|M.thermoresistible__bu -------------------MVEKSLWMRKVEADPG-----HSQWYIER--
MMAR_1164|M.marinum_M -------------------MVEQSIWMQKVAADPG-----HSRWYIER--
MUL_2851|M.ulcerans_Agy99 -------------------MVEQSIWMQKVAADPG-----HSRWYIER--
MAB_2548c|M.abscessus_ATCC_199 -------------------MVEQSLWMQKVAADPN-----HSQWYIDR--
Mflv_4890|M.gilvum_PYR-GCK -------------------MAETSLWMQKVAADPG-----HSRWYIER--
Mb0092|M.bovis_AF2122/97 --------------------------------------------------
Rv0089|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00130|M.leprae_Br4923 MAFTRIHSFLASAGNTSMYKRVWRFWYPLMTHKLGTDEIMFINWAYEEDP
MAV_4332|M.avium_104 -----FRAMARAGDDLAGEARFVDAMAPRG-ARILDAGCGPGRLGSYLAA
Mvan_1534|M.vanbaalenii_PYR-1 -----FRAMARAGDDLAGEARLVDAMAPRG-ARILDAGCGPGRVGGYLAA
MSMEG_3430|M.smegmatis_MC2_155 -----FRSLARAGEDLFGEARLVDAMAPRN-AHILDAGCGPGRLGGYLAG
TH_1247|M.thermoresistible__bu -----FRAMARAGEDLVGEARLVDAMAPRN-AHILDAGCGPGRLGGYLSA
MMAR_1164|M.marinum_M -----FRAMARAGEDLVGEARLVDSIAPRG-AHILDAGCGPGRLGRHLAA
MUL_2851|M.ulcerans_Agy99 -----FRAMARAGEDLVGEARLVDSIAPRG-AHILDAGCGPGRLGRHLAA
MAB_2548c|M.abscessus_ATCC_199 -----FRSMARDGADLAGEARLVDALVPRG-ARILDAGCGAGRVGGFLAA
Mflv_4890|M.gilvum_PYR-GCK -----FRAMARAGDDLFGEARLIDAMVPRG-ARILDAGCGPGRLGGYLAA
Mb0092|M.bovis_AF2122/97 --------MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLAR
Rv0089|M.tuberculosis_H37Rv --------MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLAR
MLBr_00130|M.leprae_Br4923 PMALPLEASDEPNRAHINLYHRTATQVNLSGKRILEVSCGHGGGASYLTR
. : . . :*:..** * . *:
MAV_4332|M.avium_104 AGH--QVVGVDVDPALIEAAEHDHPGP--RWLVGDLAELDLP--------
Mvan_1534|M.vanbaalenii_PYR-1 AGH--QVVGVDVDPALIEAAEQDYPGP--RWLVGDLAELDLP--------
MSMEG_3430|M.smegmatis_MC2_155 VGH--RVVGVDVDPALIAAAEEDYPGP--RWLVGDLAELDLP--------
TH_1247|M.thermoresistible__bu AGH--RVVGVDVDPALIEAAEQDYPGP--QYLVGDLAELDLP--------
MMAR_1164|M.marinum_M AGH--RVVGVDVDPALIEAAEQDYPGP--QWLVGDLAELDLP--------
MUL_2851|M.ulcerans_Agy99 AGH--RVVGVDVDPALIEAAEQDYPGP--QWLVGDLAELDLP--------
MAB_2548c|M.abscessus_ATCC_199 AGH--HVVGVDVDPALIEAAEHDHPGP--RWLVGDLAELDLP--------
Mflv_4890|M.gilvum_PYR-GCK AGH--HVVGVDVDPVLIDAAEKDHPGA--TWLVGDLAELDLP--------
Mb0092|M.bovis_AF2122/97 RIP--YVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAELPNAGFDAVV
Rv0089|M.tuberculosis_H37Rv RIP--YVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAELPNAGFDAVV
MLBr_00130|M.leprae_Br4923 ALHPASYTGLDLNPAGIKLCQKRHQLPGLEFVRGDAENLPFDNESFDVVI
..:*::. : .: . . :: .* :
MAV_4332|M.avium_104 -----------ARGITDPFDVIVSAG---NVMTFLAPSTR---VLVLSRL
Mvan_1534|M.vanbaalenii_PYR-1 -----------ARGITEPFDLIVSAG---NVMTFLAPSTR---VQVLARL
MSMEG_3430|M.smegmatis_MC2_155 -----------ARGIAEPFDIIVSAG---NVMTFLAPSTR---AQVLSRL
TH_1247|M.thermoresistible__bu -----------ARGIPDPFDVIVMAG---NVMAFLAPSTR---TTVLSRL
MMAR_1164|M.marinum_M -----------ARGIAEPFDVIVSAG---NVMTFLAPSTR---ARVLGRL
MUL_2851|M.ulcerans_Agy99 -----------ARGIAEPFDVIVSAG---NVMTFLAPSTR---ARVLGRL
MAB_2548c|M.abscessus_ATCC_199 -----------SRGISEPFDVIVSAG---NVMAFLAPSTR---RQVLRRL
Mflv_4890|M.gilvum_PYR-GCK -----------ARGIAEPFDVIVSAG---NVMTFLAPSTR---GEVLRRL
Mb0092|M.bovis_AF2122/97 -SNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWV
Rv0089|M.tuberculosis_H37Rv -SNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWV
MLBr_00130|M.leprae_Br4923 NIEASHCYPHFPRFLAEVVRVLRPGG--HLAYADLRPSNKVG-EWEVDFA
.* . . : * . : : ** :
MAV_4332|M.avium_104 RAHLAADGRAAIGFGAYREYEFTDFLNDAADAGFAPDLLLSS--------
Mvan_1534|M.vanbaalenii_PYR-1 RAHLRDDGRAVIGFGAGREYEYPQFLDDAAAGGLTPDLLLST--------
MSMEG_3430|M.smegmatis_MC2_155 RAHLTDNGRAVIGFGAGRDYGFEEFLADAKGAGFTPDQLLST--------
TH_1247|M.thermoresistible__bu RAHLAEDGRAAIGFGAGRDYDFDEFLADAATAGLTPDLLLST--------
MMAR_1164|M.marinum_M RAHLCSDGRAVIGFGAGRDYAFADFLDDAQAAGLVPDLLLST--------
MUL_2851|M.ulcerans_Agy99 RAHLCSDGRAVIGFGAGRDYAFADFLDDAQAAGLVPDLLLST--------
MAB_2548c|M.abscessus_ATCC_199 RSHLADPGRAVIGFGAGRDYEFSEFLSDADAAGLVPDLLLST--------
Mflv_4890|M.gilvum_PYR-GCK RTHLAAEGRAVIGFGADRDYDFAEFLDDAAGAGFVPDLLLST--------
Mb0092|M.bovis_AF2122/97 ACGMANRVKGKWEHSAPIKWPPPQTLHELRSH--VRALLPGA--------
Rv0089|M.tuberculosis_H37Rv ACGMANRVKGKWEHSAPIKWPPPQTLHELRSH--VRALLPGA--------
MLBr_00130|M.leprae_Br4923 NSRLQQLSQREINAEVLRGIASNSQKSRDLVDRHLPAFLRFAGREFIGVQ
: : . . * :
MAV_4332|M.avium_104 -WDLRPFTEDSDFLVAVLRPA----
Mvan_1534|M.vanbaalenii_PYR-1 -WDVRPFTDDSDFLVAVLRPA----
MSMEG_3430|M.smegmatis_MC2_155 -WDVRPFSEDSDFLVAILRRA----
TH_1247|M.thermoresistible__bu -WDLRPFTEDSEFLVALLRRA----
MMAR_1164|M.marinum_M -WDLRPFTDDCDFLVALLRPA----
MUL_2851|M.ulcerans_Agy99 -WDLRPFTDDCDFLVALLRPA----
MAB_2548c|M.abscessus_ATCC_199 -WDLRPFTDKSDFLVALLRRDDAPS
Mflv_4890|M.gilvum_PYR-GCK -WDLRPWREDSGFLVAVLRRM----
Mb0092|M.bovis_AF2122/97 -CIRRLLYG--RVLVTWRAPV----
Rv0089|M.tuberculosis_H37Rv -CIRRLLYG--RVLVTWRAPV----
MLBr_00130|M.leprae_Br4923 GTQLSRYLEGGELSYRMYSFAKD--
.