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AETSLWMQKVAADPGHSRWYIERFRAMARAGDDLFGEARLIDAMVPRGARILDAGCGPGRLGGYLAAAGH HVVGVDVDPVLIDAAEKDHPGATWLVGDLAELDLPARGIAEPFDVIVSAGNVMTFLAPSTRGEVLRRLRT HLAAEGRAVIGFGADRDYDFAEFLDDAAGAGFVPDLLLSTWDLRPWREDSGFLVAVLRRM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4890 | - | - | 100% (201) | methyltransferase type 12 |
| M. gilvum PYR-GCK | Mflv_3090 | - | 9e-22 | 35.18% (199) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_4692 | - | 1e-07 | 36.43% (129) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0092 | - | 1e-07 | 39.02% (82) | methyltransferase/methylase |
| M. tuberculosis H37Rv | Rv0089 | - | 1e-07 | 39.02% (82) | methyltransferase/methylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2548c | - | 1e-91 | 80.00% (200) | hypothetical protein MAB_2548c |
| M. marinum M | MMAR_1164 | - | 3e-92 | 80.90% (199) | methyltransferase |
| M. avium 104 | MAV_4332 | - | 1e-93 | 82.41% (199) | SAM-dependent methyltransferases |
| M. smegmatis MC2 155 | MSMEG_3430 | - | 1e-92 | 80.50% (200) | SAM-dependent methyltransferase |
| M. thermoresistible (build 8) | TH_1247 | - | 8e-90 | 79.50% (200) | SAM-dependent methyltransferase |
| M. ulcerans Agy99 | MUL_2851 | - | 2e-92 | 80.90% (199) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1534 | - | 6e-94 | 81.41% (199) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3430|M.smegmatis_MC2_155 MVEQSLWMQKVAADPGHSQWYIERFRSLARAGEDLFGEARLVDAMAPRN-
TH_1247|M.thermoresistible__bu MVEKSLWMRKVEADPGHSQWYIERFRAMARAGEDLVGEARLVDAMAPRN-
MMAR_1164|M.marinum_M MVEQSIWMQKVAADPGHSRWYIERFRAMARAGEDLVGEARLVDSIAPRG-
MUL_2851|M.ulcerans_Agy99 MVEQSIWMQKVAADPGHSRWYIERFRAMARAGEDLVGEARLVDSIAPRG-
MAV_4332|M.avium_104 MVEQSIWMQKVAADPGHSHWYIERFRAMARAGDDLAGEARFVDAMAPRG-
Mvan_1534|M.vanbaalenii_PYR-1 MVETSIWMQKVAADPGHSRWYIERFRAMARAGDDLAGEARLVDAMAPRG-
MAB_2548c|M.abscessus_ATCC_199 MVEQSLWMQKVAADPNHSQWYIDRFRSMARDGADLAGEARLVDALVPRG-
Mflv_4890|M.gilvum_PYR-GCK MAETSLWMQKVAADPGHSRWYIERFRAMARAGDDLFGEARLIDAMVPRG-
Mb0092|M.bovis_AF2122/97 ---------------------------MDQPWNANIHYDALLDAMVPLGT
Rv0089|M.tuberculosis_H37Rv ---------------------------MDQPWNANIHYDALLDAMVPLGT
: : ::*::.* .
MSMEG_3430|M.smegmatis_MC2_155 AHILDAGCGPGRLGGYLAGVGHRVVGVDVDPALIAAAEEDYPGP--RWLV
TH_1247|M.thermoresistible__bu AHILDAGCGPGRLGGYLSAAGHRVVGVDVDPALIEAAEQDYPGP--QYLV
MMAR_1164|M.marinum_M AHILDAGCGPGRLGRHLAAAGHRVVGVDVDPALIEAAEQDYPGP--QWLV
MUL_2851|M.ulcerans_Agy99 AHILDAGCGPGRLGRHLAAAGHRVVGVDVDPALIEAAEQDYPGP--QWLV
MAV_4332|M.avium_104 ARILDAGCGPGRLGSYLAAAGHQVVGVDVDPALIEAAEHDHPGP--RWLV
Mvan_1534|M.vanbaalenii_PYR-1 ARILDAGCGPGRVGGYLAAAGHQVVGVDVDPALIEAAEQDYPGP--RWLV
MAB_2548c|M.abscessus_ATCC_199 ARILDAGCGAGRVGGFLAAAGHHVVGVDVDPALIEAAEHDHPGP--RWLV
Mflv_4890|M.gilvum_PYR-GCK ARILDAGCGPGRLGGYLAAAGHHVVGVDVDPVLIDAAEKDHPGA--TWLV
Mb0092|M.bovis_AF2122/97 QCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRFANAPIRWLH
Rv0089|M.tuberculosis_H37Rv QCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRFANAPIRWLH
:**.*** * :. *: *..**:*. :: *: .... :*
MSMEG_3430|M.smegmatis_MC2_155 GDLAELDLP------------------ARGIAEPFDIIVSAG---NVMTF
TH_1247|M.thermoresistible__bu GDLAELDLP------------------ARGIPDPFDVIVMAG---NVMAF
MMAR_1164|M.marinum_M GDLAELDLP------------------ARGIAEPFDVIVSAG---NVMTF
MUL_2851|M.ulcerans_Agy99 GDLAELDLP------------------ARGIAEPFDVIVSAG---NVMTF
MAV_4332|M.avium_104 GDLAELDLP------------------ARGITDPFDVIVSAG---NVMTF
Mvan_1534|M.vanbaalenii_PYR-1 GDLAELDLP------------------ARGITEPFDLIVSAG---NVMTF
MAB_2548c|M.abscessus_ATCC_199 GDLAELDLP------------------SRGISEPFDVIVSAG---NVMAF
Mflv_4890|M.gilvum_PYR-GCK GDLAELDLP------------------ARGIAEPFDVIVSAG---NVMTF
Mb0092|M.bovis_AF2122/97 ADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTF
Rv0089|M.tuberculosis_H37Rv ADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTF
.*: :** :* . :. :* .* *::*
MSMEG_3430|M.smegmatis_MC2_155 LAPSTR---AQVLSRLRAHLTDNGRAVIGFGAGRDYGFEEFLADAKGAGF
TH_1247|M.thermoresistible__bu LAPSTR---TTVLSRLRAHLAEDGRAAIGFGAGRDYDFDEFLADAATAGL
MMAR_1164|M.marinum_M LAPSTR---ARVLGRLRAHLCSDGRAVIGFGAGRDYAFADFLDDAQAAGL
MUL_2851|M.ulcerans_Agy99 LAPSTR---ARVLGRLRAHLCSDGRAVIGFGAGRDYAFADFLDDAQAAGL
MAV_4332|M.avium_104 LAPSTR---VLVLSRLRAHLAADGRAAIGFGAYREYEFTDFLNDAADAGF
Mvan_1534|M.vanbaalenii_PYR-1 LAPSTR---VQVLARLRAHLRDDGRAVIGFGAGREYEYPQFLDDAAAGGL
MAB_2548c|M.abscessus_ATCC_199 LAPSTR---RQVLRRLRSHLADPGRAVIGFGAGRDYEFSEFLSDADAAGL
Mflv_4890|M.gilvum_PYR-GCK LAPSTR---GEVLRRLRTHLAAEGRAVIGFGADRDYDFAEFLDDAAGAGF
Mb0092|M.bovis_AF2122/97 VTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSH--
Rv0089|M.tuberculosis_H37Rv VTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSH--
::** * : : : :. ..* .: : * :
MSMEG_3430|M.smegmatis_MC2_155 TPDQLLSTWDVRPFSEDSDFLVAILRRA----
TH_1247|M.thermoresistible__bu TPDLLLSTWDLRPFTEDSEFLVALLRRA----
MMAR_1164|M.marinum_M VPDLLLSTWDLRPFTDDCDFLVALLRPA----
MUL_2851|M.ulcerans_Agy99 VPDLLLSTWDLRPFTDDCDFLVALLRPA----
MAV_4332|M.avium_104 APDLLLSSWDLRPFTEDSDFLVAVLRPA----
Mvan_1534|M.vanbaalenii_PYR-1 TPDLLLSTWDVRPFTDDSDFLVAVLRPA----
MAB_2548c|M.abscessus_ATCC_199 VPDLLLSTWDLRPFTDKSDFLVALLRRDDAPS
Mflv_4890|M.gilvum_PYR-GCK VPDLLLSTWDLRPWREDSGFLVAVLRRM----
Mb0092|M.bovis_AF2122/97 VRALLPGACIRRLLYG--RVLVTWRAPV----
Rv0089|M.tuberculosis_H37Rv VRALLPGACIRRLLYG--RVLVTWRAPV----
. * .: * .**: