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MSTTITVEGMSCAGCANSVRAELTHIPGVREVDVDISNGTVTIDSDNPVDPAAIREAVEEAGYTLAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4448 | - | - | 100% (67) | heavy metal transport/detoxification protein |
| M. vanbaalenii PYR-1 | Mvan_3669 | - | 1e-08 | 44.29% (70) | heavy metal transport/detoxification protein |
| M. vanbaalenii PYR-1 | Mvan_3670 | - | 1e-07 | 39.68% (63) | heavy metal translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0095 | ctpA | 1e-08 | 42.37% (59) | cation transporter P-type ATPase A |
| M. gilvum PYR-GCK | Mflv_2847 | - | 4e-11 | 47.69% (65) | heavy metal transport/detoxification protein |
| M. tuberculosis H37Rv | Rv0092 | ctpA | 1e-08 | 42.37% (59) | cation transporter P-type ATPase A |
| M. leprae Br4923 | MLBr_02000 | ctpB | 6e-07 | 43.33% (60) | cation-transporting ATPase |
| M. abscessus ATCC 19977 | MAB_0454c | - | 5e-12 | 44.78% (67) | putative metal-binding protein |
| M. marinum M | MMAR_0233 | - | 7e-09 | 38.60% (57) | hypothetical protein MMAR_0233 |
| M. avium 104 | MAV_5245 | - | 3e-08 | 42.11% (57) | hypothetical protein MAV_5245 |
| M. smegmatis MC2 155 | MSMEG_5016 | - | 1e-15 | 58.73% (63) | hypothetical protein MSMEG_5016 |
| M. thermoresistible (build 8) | TH_2912 | - | 4e-08 | 35.82% (67) | PUTATIVE Heavy metal transport/detoxification protein |
| M. ulcerans Agy99 | MUL_4881 | - | 4e-09 | 38.60% (57) | hypothetical protein MUL_4881 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0233|M.marinum_M ---------------------------------------------MNTSE
MUL_4881|M.ulcerans_Agy99 ---------------------------------------------MNTSE
MAV_5245|M.avium_104 ---------------------------------------------MPTSE
Mflv_2847|M.gilvum_PYR-GCK MPRPASTRHQQEPEEPTLAPYPRGVYLDVRIPGRGTTESEDGSSVMSTIT
TH_2912|M.thermoresistible__bu ---------------------------------------------MS-VE
MAB_0454c|M.abscessus_ATCC_199 ---------------------------------------------MSTTA
MSMEG_5016|M.smegmatis_MC2_155 ---------------------------------------------MTTQT
Mvan_4448|M.vanbaalenii_PYR-1 ---------------------------------------------MS-TT
Mb0095|M.bovis_AF2122/97 ------------------------------MTAAVTG---EHHASVQRIQ
Rv0092|M.tuberculosis_H37Rv ------------------------------MTTAVTG---EHHASVQRIQ
MLBr_02000|M.leprae_Br4923 ------------------------------MTASLVEDTNNNHESVRRIQ
:
MMAR_0233|M.marinum_M YQVAGMRCGHCESAIRSEVAQIPGVATVAVSARTGRLLVAGSAPIDPTTV
MUL_4881|M.ulcerans_Agy99 YQVAGMRCGHCESAIRSEVAQIPGVATVAVSARTGRLLVAGSAPIDPTTV
MAV_5245|M.avium_104 YQVSGMSCGHCEAAVHSEVARIPGVDGVSVSADTGRLVVTSAVPIDADAV
Mflv_2847|M.gilvum_PYR-GCK YAVTGMTCGHCELSVREEVSGVAGVQDVEVSATAGTLIVTSSGPVDDAQI
TH_2912|M.thermoresistible__bu IHVRGMSCGHCVSAITSAVRPLPGVEGVEVDLDAGVVRVTGTP--DEGAV
MAB_0454c|M.abscessus_ATCC_199 LKVSGMTCGHCVAAVREQVAAVPGVTGVQVDVATGTVTVTSSGPLPAEAV
MSMEG_5016|M.smegmatis_MC2_155 VTVTGMTCGHCVTSVREEVGSIPGVTTVDVDLATGQVTIGSDRQLDDEAI
Mvan_4448|M.vanbaalenii_PYR-1 ITVEGMSCAGCANSVRAELTHIPGVREVDVDISNGTVTIDSDNPVDPAAI
Mb0095|M.bovis_AF2122/97 LRISGMSCSACAHRVESTLNKLPGVR-AAVNFGTRVATIDTSEAVDAAAL
Rv0092|M.tuberculosis_H37Rv LRISGMSCSACAHRVESTLNKLPGVR-AAVNFGTRVATIDTSEAVDAAAL
MLBr_02000|M.leprae_Br4923 LDVAGMLCAACASRVETKLNKIPGVR-ASVNFATRVATIDAVD-VAVDEL
: ** *. * : : :.** . *. : :
MMAR_0233|M.marinum_M LGAIDEAGYQAVLVA-----------------------------------
MUL_4881|M.ulcerans_Agy99 LGAIDEAGYQAVLVA-----------------------------------
MAV_5245|M.avium_104 LGAVDEAGFQAVLVA-----------------------------------
Mflv_2847|M.gilvum_PYR-GCK LRAVDEAGYSAVRVV-----------------------------------
TH_2912|M.thermoresistible__bu TAAIEDCGYDVPGA------------------------------------
MAB_0454c|M.abscessus_ATCC_199 HAAIRAAGYALAS-------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 REAVAEAGYAVAS-------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 REAVEEAGYTLAG-------------------------------------
Mb0095|M.bovis_AF2122/97 CQAVRRAGYQADLCTDDGRSASDPDADHARQLLIRLAIAAVLFVPVADLS
Rv0092|M.tuberculosis_H37Rv CQAVRRAGYQADLCTDDGRSASDPDADHARQLLIRLAIAAVLFVPVADLS
MLBr_02000|M.leprae_Br4923 RQVIEQAGYRATAHAESAVEEIDPDADYARNLLRRLIVAALLFVPLADLS
.: .*:
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 VMFGVVPATRFTGWQWVLSALALPVVTWAAWPFHRVAMRNARHHAASMET
Rv0092|M.tuberculosis_H37Rv VMFGVVPATRFTGWQWVLSALALPVVTWAAWPFHRVAMRNARHHAASMET
MLBr_02000|M.leprae_Br4923 TMFAIVPTNRFPGWGYLLTALAAPIVTWAAWPFHRVALRNARYRAASMET
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 LISVGITAATIWSLYTVFGNHSPIERSGIWQALLGSDAIYFEVAAGVTVF
Rv0092|M.tuberculosis_H37Rv LISVGITAATIWSLYTVFGNHSPIERSGIWQALLGSDAIYFEVAAGVTVF
MLBr_02000|M.leprae_Br4923 LISAGILAATGWSLSTIFVDKEPRQTHGIWQAILHSDSIYFEVAAGVTVF
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 VLVGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQ
Rv0092|M.tuberculosis_H37Rv VLVGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQ
MLBr_02000|M.leprae_Br4923 VLAGRFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQ
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 QRFVVRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTV
Rv0092|M.tuberculosis_H37Rv QRFVVRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTV
MLBr_02000|M.leprae_Br4923 QHFLVRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTV
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 LDGRLIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAV
Rv0092|M.tuberculosis_H37Rv LDGRLIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAV
MLBr_02000|M.leprae_Br4923 LDGRLVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMV
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 LVIAALTAAGWLIAGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASG
Rv0092|M.tuberculosis_H37Rv LVIAALTAAGWLIAGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASG
MLBr_02000|M.leprae_Br4923 FVIAGLAGASWLLAGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASG
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 RGAQLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGWEA
Rv0092|M.tuberculosis_H37Rv RGAQLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGWEA
MLBr_02000|M.leprae_Br4923 RGAQLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGWCS
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 DQVLALAATVEAASEHSVALAIAAATTRRDAVTDFRAIPGRGVSGTVSGR
Rv0092|M.tuberculosis_H37Rv DQVLALAATVEAASEHSVALAIAAATTRRDAVTDFRAIPGRGVSGTVSGR
MLBr_02000|M.leprae_Br4923 GEVLALASAVEAASEHSVATAIVAAYADPRPVADFVAFAGCGVSGVVAEH
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 AVRVGKPSWIG-SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAVA
Rv0092|M.tuberculosis_H37Rv AVRVGKPSWIG-SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAVA
MLBr_02000|M.leprae_Br4923 HVKIGKPSWVTRNAPCDVVLESARREGESRGETVVFVSVDGVACGAVAIA
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 DAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGIDEVIADILP
Rv0092|M.tuberculosis_H37Rv DAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGIDEVIADILP
MLBr_02000|M.leprae_Br4923 DTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGIDTVIADMLP
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 EGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAA
Rv0092|M.tuberculosis_H37Rv EGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAA
MLBr_02000|M.leprae_Br4923 EAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGRGTDVAIGAA
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 DIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAGLLN
Rv0092|M.tuberculosis_H37Rv DIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAGLLN
MLBr_02000|M.leprae_Br4923 DLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPIASSGLLN
MMAR_0233|M.marinum_M ----------------------------------------------
MUL_4881|M.ulcerans_Agy99 ----------------------------------------------
MAV_5245|M.avium_104 ----------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK ----------------------------------------------
TH_2912|M.thermoresistible__bu ----------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 ----------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 ----------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 ----------------------------------------------
Mb0095|M.bovis_AF2122/97 PLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA
Rv0092|M.tuberculosis_H37Rv PLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA
MLBr_02000|M.leprae_Br4923 PLIAGAAMAFSSFFVVSNSLRLSNFG-------------LSQTSD-