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STTALKVSGMTCGHCVAAVREQVAAVPGVTGVQVDVATGTVTVTSSGPLPAEAVHAAIRAAGYALAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0454c | - | - | 100% (68) | putative metal-binding protein |
| M. abscessus ATCC 19977 | MAB_0667 | - | 1e-04 | 36.36% (66) | heavy metal transport/detoxification protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0095 | ctpA | 3e-05 | 35.59% (59) | cation transporter P-type ATPase A |
| M. gilvum PYR-GCK | Mflv_2847 | - | 3e-13 | 49.23% (65) | heavy metal transport/detoxification protein |
| M. tuberculosis H37Rv | Rv0092 | ctpA | 3e-05 | 35.59% (59) | cation transporter P-type ATPase A |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0233 | - | 1e-11 | 45.31% (64) | hypothetical protein MMAR_0233 |
| M. avium 104 | MAV_5245 | - | 4e-14 | 51.56% (64) | hypothetical protein MAV_5245 |
| M. smegmatis MC2 155 | MSMEG_5016 | - | 2e-17 | 55.88% (68) | hypothetical protein MSMEG_5016 |
| M. thermoresistible (build 8) | TH_2912 | - | 1e-09 | 49.15% (59) | PUTATIVE Heavy metal transport/detoxification protein |
| M. ulcerans Agy99 | MUL_4881 | - | 7e-12 | 45.31% (64) | hypothetical protein MUL_4881 |
| M. vanbaalenii PYR-1 | Mvan_4448 | - | 6e-12 | 44.78% (67) | heavy metal transport/detoxification protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0233|M.marinum_M ---------------------------------------------MNTSE
MUL_4881|M.ulcerans_Agy99 ---------------------------------------------MNTSE
MAV_5245|M.avium_104 ---------------------------------------------MPTSE
Mflv_2847|M.gilvum_PYR-GCK MPRPASTRHQQEPEEPTLAPYPRGVYLDVRIPGRGTTESEDGSSVMSTIT
TH_2912|M.thermoresistible__bu ---------------------------------------------MS-VE
MAB_0454c|M.abscessus_ATCC_199 ---------------------------------------------MSTTA
MSMEG_5016|M.smegmatis_MC2_155 ---------------------------------------------MTTQT
Mvan_4448|M.vanbaalenii_PYR-1 ---------------------------------------------MS-TT
Mb0095|M.bovis_AF2122/97 ---------------------------------MTAAVTGEHHASVQRIQ
Rv0092|M.tuberculosis_H37Rv ---------------------------------MTTAVTGEHHASVQRIQ
:
MMAR_0233|M.marinum_M YQVAGMRCGHCESAIRSEVAQIPGVATVAVSARTGRLLVAGSAPIDPTTV
MUL_4881|M.ulcerans_Agy99 YQVAGMRCGHCESAIRSEVAQIPGVATVAVSARTGRLLVAGSAPIDPTTV
MAV_5245|M.avium_104 YQVSGMSCGHCEAAVHSEVARIPGVDGVSVSADTGRLVVTSAVPIDADAV
Mflv_2847|M.gilvum_PYR-GCK YAVTGMTCGHCELSVREEVSGVAGVQDVEVSATAGTLIVTSSGPVDDAQI
TH_2912|M.thermoresistible__bu IHVRGMSCGHCVSAITSAVRPLPGVEGVEVDLDAGVVRVTGTP--DEGAV
MAB_0454c|M.abscessus_ATCC_199 LKVSGMTCGHCVAAVREQVAAVPGVTGVQVDVATGTVTVTSSGPLPAEAV
MSMEG_5016|M.smegmatis_MC2_155 VTVTGMTCGHCVTSVREEVGSIPGVTTVDVDLATGQVTIGSDRQLDDEAI
Mvan_4448|M.vanbaalenii_PYR-1 ITVEGMSCAGCANSVRAELTHIPGVREVDVDISNGTVTIDSDNPVDPAAI
Mb0095|M.bovis_AF2122/97 LRISGMSCSACAHRVESTLNKLPGVR-AAVNFGTRVATIDTSEAVDAAAL
Rv0092|M.tuberculosis_H37Rv LRISGMSCSACAHRVESTLNKLPGVR-AAVNFGTRVATIDTSEAVDAAAL
: ** *. * : : :.** . *. : :
MMAR_0233|M.marinum_M LGAIDEAGYQAVLVA-----------------------------------
MUL_4881|M.ulcerans_Agy99 LGAIDEAGYQAVLVA-----------------------------------
MAV_5245|M.avium_104 LGAVDEAGFQAVLVA-----------------------------------
Mflv_2847|M.gilvum_PYR-GCK LRAVDEAGYSAVRVV-----------------------------------
TH_2912|M.thermoresistible__bu TAAIEDCGYDVPGA------------------------------------
MAB_0454c|M.abscessus_ATCC_199 HAAIRAAGYALAS-------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 REAVAEAGYAVAS-------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 REAVEEAGYTLAG-------------------------------------
Mb0095|M.bovis_AF2122/97 CQAVRRAGYQADLCTDDGRSASDPDADHARQLLIRLAIAAVLFVPVADLS
Rv0092|M.tuberculosis_H37Rv CQAVRRAGYQADLCTDDGRSASDPDADHARQLLIRLAIAAVLFVPVADLS
*: .*:
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 VMFGVVPATRFTGWQWVLSALALPVVTWAAWPFHRVAMRNARHHAASMET
Rv0092|M.tuberculosis_H37Rv VMFGVVPATRFTGWQWVLSALALPVVTWAAWPFHRVAMRNARHHAASMET
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 LISVGITAATIWSLYTVFGNHSPIERSGIWQALLGSDAIYFEVAAGVTVF
Rv0092|M.tuberculosis_H37Rv LISVGITAATIWSLYTVFGNHSPIERSGIWQALLGSDAIYFEVAAGVTVF
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 VLVGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQ
Rv0092|M.tuberculosis_H37Rv VLVGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQ
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 QRFVVRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTV
Rv0092|M.tuberculosis_H37Rv QRFVVRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTV
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 LDGRLIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAV
Rv0092|M.tuberculosis_H37Rv LDGRLIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAV
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 LVIAALTAAGWLIAGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASG
Rv0092|M.tuberculosis_H37Rv LVIAALTAAGWLIAGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASG
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 RGAQLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGWEA
Rv0092|M.tuberculosis_H37Rv RGAQLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGWEA
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 DQVLALAATVEAASEHSVALAIAAATTRRDAVTDFRAIPGRGVSGTVSGR
Rv0092|M.tuberculosis_H37Rv DQVLALAATVEAASEHSVALAIAAATTRRDAVTDFRAIPGRGVSGTVSGR
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 AVRVGKPSWIGSSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAVAD
Rv0092|M.tuberculosis_H37Rv AVRVGKPSWIGSSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAVAD
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 AVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGIDEVIADILPE
Rv0092|M.tuberculosis_H37Rv AVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGIDEVIADILPE
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 GKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAAD
Rv0092|M.tuberculosis_H37Rv GKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAAD
MMAR_0233|M.marinum_M --------------------------------------------------
MUL_4881|M.ulcerans_Agy99 --------------------------------------------------
MAV_5245|M.avium_104 --------------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK --------------------------------------------------
TH_2912|M.thermoresistible__bu --------------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0095|M.bovis_AF2122/97 IILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAGLLNP
Rv0092|M.tuberculosis_H37Rv IILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAGLLNP
MMAR_0233|M.marinum_M ---------------------------------------------
MUL_4881|M.ulcerans_Agy99 ---------------------------------------------
MAV_5245|M.avium_104 ---------------------------------------------
Mflv_2847|M.gilvum_PYR-GCK ---------------------------------------------
TH_2912|M.thermoresistible__bu ---------------------------------------------
MAB_0454c|M.abscessus_ATCC_199 ---------------------------------------------
MSMEG_5016|M.smegmatis_MC2_155 ---------------------------------------------
Mvan_4448|M.vanbaalenii_PYR-1 ---------------------------------------------
Mb0095|M.bovis_AF2122/97 LVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA
Rv0092|M.tuberculosis_H37Rv LVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA