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MSELVLTQVEDRVALITINDPDRRNAVTAEISAALRAAVEAAEADTGVHAVIVTGAGKAFCAGADLTALG AATEDGLRVIYDGFLAVAECNLPTIAAVNGPAVGAGLNLALAADVRIAGPAALFDPRFQKLGIHPGGGAT WMLQRAIGPQAARAALLFGMRFDAESAVRHGLALEVADDPVAAARELAAGPASAPRDVVVSTKASMRATY NPGISDLHQHHMAVDIEIGPQARSIESPEFAARLAAAQRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4083 | - | - | 100% (250) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | 3e-30 | 37.30% (252) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1871 | - | 7e-30 | 38.03% (234) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2511 | echA14 | 1e-103 | 75.60% (250) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2557 | - | 1e-120 | 88.80% (250) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv2486 | echA14 | 1e-103 | 75.60% (250) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-23 | 30.97% (226) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3124 | - | 5e-27 | 38.16% (207) | enoyl-CoA hydratase |
| M. marinum M | MMAR_3510 | echA8_5 | 4e-29 | 43.09% (188) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_1678 | - | 1e-105 | 75.49% (253) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_4709 | - | 1e-114 | 81.93% (249) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_0952 | echA14 | 1e-105 | 78.51% (242) | PROBABLE ENOYL-CoA HYDRATASE ECHA14 (ENOYL HYDRASE) |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 2e-28 | 42.55% (188) | enoyl-CoA hydratase, EchA8_5 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2511|M.bovis_AF2122/97 MAQYDPVLLSVDKHVALITVNDPDRRNAVT-DEMSAQLRAAIQRAEGDPD
Rv2486|M.tuberculosis_H37Rv MAQYDPVLLSVDKHVALITVNDPDRRNAVT-DEMSAQLRAAIQRAEGDPD
MAV_1678|M.avium_104 MAQSNLVLLDIENHVALITVNDPDRRNAVT-AEMSGRLREAVERVEADSD
Mvan_4083|M.vanbaalenii_PYR-1 --MSELVLTQVEDRVALITINDPDRRNAVT-AEISAALRAAVEAAEADTG
Mflv_2557|M.gilvum_PYR-GCK --MSELVLMQVTDRVALITINDPDRRNAVT-AEISAALRAAVSAAEADPD
MSMEG_4709|M.smegmatis_MC2_155 --MADSVLVETSDRIAVITVNDPDRRNAVT-FEMSAALRSAVEAAEADPD
TH_0952|M.thermoresistible__bu --------MAVEERVAVITVNDPERRNAVT-FEMSEALRAAVARAEADEA
MLBr_02402|M.leprae_Br4923 -MKYDTILVDGYQRVGIITLNRPQALNALN-SQMMNEITNAAKELDIDPD
MAB_3124|M.abscessus_ATCC_1997 -MTEPILLTHTEDRICTITLNRPQARNALS-TALGEEIVKAVTAADADEN
MMAR_3510|M.marinum_M --MNTALDITTNGPIRTWTINLPDVGNAITGKDFIAAFEAAVDDANIDTS
MUL_2758|M.ulcerans_Agy99 --MNTALDITTNGPIRTWTINLPDVGNAITGRDFIAAFEAAVDDANIDTS
: *:* *: **:. : : * : *
Mb2511|M.bovis_AF2122/97 VHAVVVTGAGKAFCAGADLSALG-------AGVGDPAEPRLLRLYDGFMA
Rv2486|M.tuberculosis_H37Rv VHAVVVTGAGKAFCAGADLSALG-------AGVGDPAEPRLLRLYDGFMA
MAV_1678|M.avium_104 VHAVVITGAGKAFCAGADLSALG-------AAGGGSAETGLQQLYDGFMA
Mvan_4083|M.vanbaalenii_PYR-1 VHAVIVTGAGKAFCAGADLTALG-------AAT----EDGLRVIYDGFLA
Mflv_2557|M.gilvum_PYR-GCK VHAVIVTGAGKAFCAGADLTALG-------AAT----EDGLRVIYDGFLA
MSMEG_4709|M.smegmatis_MC2_155 VHAVVVTGAGKAFCAGADLAALG-------TAT----EDGLRKIYDGFLA
TH_0952|M.thermoresistible__bu VHAVVVTGAGRAFCAGADLAALR-------TAT----EDDLRRLYDGFIA
MLBr_02402|M.leprae_Br4923 VGAILITGSPKVFAAGADIKEMA---------SLTFTDAFDADFFSAWGK
MAB_3124|M.abscessus_ATCC_1997 VDVMILTAADPVFCAGVDLKELG---------SGDRAESLDPWWP-----
MMAR_3510|M.marinum_M VRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQRQAYTDGIQRIPRA
MUL_2758|M.ulcerans_Agy99 VRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQRQAYTDGIQRIPRA
* .:::*.: *..* :: : :
Mb2511|M.bovis_AF2122/97 VSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDARFQKLGLHPG
Rv2486|M.tuberculosis_H37Rv VSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDARFQKLGLHPG
MAV_1678|M.avium_104 IGSCRLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDPRFQQLGLHPG
Mvan_4083|M.vanbaalenii_PYR-1 VAECNLPTIAAVNGPAVGAGLNLALAADVRIAGPAALFDPRFQKLGIHPG
Mflv_2557|M.gilvum_PYR-GCK VAQCSLPTIAAVNGAAVGAGLNLALAADVRIAGPHAMFDPRFQKLGIHPG
MSMEG_4709|M.smegmatis_MC2_155 VAHCTLPTIAAVNGAAVGAGLNLALAADVRIAGPHALFDPRFQKLGIHPG
TH_0952|M.thermoresistible__bu VARCTLPTVAAVNGPAVGAGLNLALAADVRIAGPTAVFDPRFQKLGIHPG
MLBr_02402|M.leprae_Br4923 LAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPG
MAB_3124|M.abscessus_ATCC_1997 --ELSKPVIGAINGAAVTGGLELALACDILIASEKARFADTHARVGILPT
MMAR_3510|M.marinum_M LARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRASFAESFVALGIIPG
MUL_2758|M.ulcerans_Agy99 LARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRASFAESFVALGIIPG
* :.*: * *: .* :**: .*: **. * * :*: *
Mb2511|M.bovis_AF2122/97 GGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLALMVA--DDPVTAA
Rv2486|M.tuberculosis_H37Rv GGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLALMVA--DDPVTAA
MAV_1678|M.avium_104 GGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGLALSVA--DDPVAAA
Mvan_4083|M.vanbaalenii_PYR-1 GGATWMLQRAIGPQAARAALLFGMRFDAESAVRHGLALEVA--DDPVAAA
Mflv_2557|M.gilvum_PYR-GCK GGATWMLQRITGPQAARAALLFGMRFDADAAVRHGLALEVA--DDPVARA
MSMEG_4709|M.smegmatis_MC2_155 GGATWMLQRAAGPEVARAALLFGMRFDAEAAVRHGLALTVA--DDPLAAA
TH_0952|M.thermoresistible__bu GGATWMLQRAIGPQAARASLLFGLGFDAEAAVRSGLALKIA--EDPVAAA
MLBr_02402|M.leprae_Br4923 MGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEA
MAB_3124|M.abscessus_ATCC_1997 WGLTTLLPLSVGRGLARRMSLTGDYLSAEDALRAGLVTEVVAHNELLPAA
MMAR_3510|M.marinum_M DGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMVSRVVPHDDLLPQA
MUL_2758|M.ulcerans_Agy99 DGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMVSRVVPHGDLLPQA
* : * * * * * :.* * . *:. :. : :. *
Mb2511|M.bovis_AF2122/97 LELAAGPAAAPREVVLASKATMRATASPGSLDLEQHELAKRLELGPQAKS
Rv2486|M.tuberculosis_H37Rv LELAAGPAAAPREVVLASKATMRATASPGSLDLEQHELAKRLELGPQAKS
MAV_1678|M.avium_104 LELAAGPAAAPREVVLATKATMRATISLGSLDNEQHQHAMRTELGPQAHS
Mvan_4083|M.vanbaalenii_PYR-1 RELAAGPASAPRDVVVSTKASMRATYNPGISDLHQHHMAVDIEIGPQARS
Mflv_2557|M.gilvum_PYR-GCK RELAAGPAGAPRDVVVATKASMRATAHPGTDDLEQHRLAVDIEIVPQATS
MSMEG_4709|M.smegmatis_MC2_155 RELASGPASAPREVVLATKASMRATANPGVIDTDQHRAAVDIELGPQARS
TH_0952|M.thermoresistible__bu RELAAGPAAAPRDVVVATKASMRATANPGVPDTEQHMRAVDTELPPQAAS
MLBr_02402|M.leprae_Br4923 KAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQ
MAB_3124|M.abscessus_ATCC_1997 KRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHRWIDQNSI
MMAR_3510|M.marinum_M QELAERIVKNPAHALRMAKRLLQESRVGSLESTLGMAAAMQPLAHRDPEH
MUL_2758|M.ulcerans_Agy99 QELAERIVKNPAHALRMAKRLLQESRVGSLESTLGMAAAMQPLAHRDPEH
:* . . .
Mb2511|M.bovis_AF2122/97 VQSPEFAARLAAAQHR----
Rv2486|M.tuberculosis_H37Rv VQSPEFAARLAAAQHR----
MAV_1678|M.avium_104 IQSPEFAQRLAAAQRK----
Mvan_4083|M.vanbaalenii_PYR-1 IESPEFAARLAAAQRR----
Mflv_2557|M.gilvum_PYR-GCK IESPEFAARLAAAKRR----
MSMEG_4709|M.smegmatis_MC2_155 IESPEFAARLAARRK-----
TH_0952|M.thermoresistible__bu IAAPAFAERIAAALRR----
MLBr_02402|M.leprae_Br4923 SEGMAAFIEKRAPQFTHR--
MAB_3124|M.abscessus_ATCC_1997 AEGVEARRTAIMERGRSQNA
MMAR_3510|M.marinum_M QQRIAKWRTR----------
MUL_2758|M.ulcerans_Agy99 QQRIAKWRTRIAKWRTR---