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MAQYDPVLLSVDKHVALITVNDPDRRNAVTDEMSAQLRAAIQRAEGDPDVHAVVVTGAGKAFCAGADLSA LGAGVGDPAEPRLLRLYDGFMAVSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDARFQKLGLH PGGGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLALMVADDPVTAALELAAGPAAAPREVVLASKA TMRATASPGSLDLEQHELAKRLELGPQAKSVQSPEFAARLAAAQHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2511 | echA14 | - | 100% (256) | enoyl-CoA hydratase |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 1e-25 | 33.62% (232) | enoyl-CoA hydratase |
| M. bovis AF2122 / 97 | Mb0996c | echA7 | 7e-24 | 34.30% (207) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2557 | - | 1e-101 | 74.80% (250) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv2486 | echA14 | 1e-142 | 100.00% (256) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 6e-24 | 32.57% (218) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0834 | - | 9e-28 | 37.72% (228) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_3510 | echA8_5 | 4e-25 | 36.74% (215) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_1678 | - | 1e-113 | 81.64% (256) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_4709 | - | 1e-102 | 75.40% (248) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_0952 | echA14 | 1e-93 | 70.56% (248) | PROBABLE ENOYL-CoA HYDRATASE ECHA14 (ENOYL HYDRASE) |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 8e-25 | 33.19% (229) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4083 | - | 1e-103 | 75.60% (250) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2511|M.bovis_AF2122/97 MAQYDPVLLSVDKHVALITVNDPDRRNAVT-DEMSAQLRAAIQRAEGDPD
Rv2486|M.tuberculosis_H37Rv MAQYDPVLLSVDKHVALITVNDPDRRNAVT-DEMSAQLRAAIQRAEGDPD
MAV_1678|M.avium_104 MAQSNLVLLDIENHVALITVNDPDRRNAVT-AEMSGRLREAVERVEADSD
Mflv_2557|M.gilvum_PYR-GCK --MSELVLMQVTDRVALITINDPDRRNAVT-AEISAALRAAVSAAEADPD
Mvan_4083|M.vanbaalenii_PYR-1 --MSELVLTQVEDRVALITINDPDRRNAVT-AEISAALRAAVEAAEADTG
MSMEG_4709|M.smegmatis_MC2_155 --MADSVLVETSDRIAVITVNDPDRRNAVT-FEMSAALRSAVEAAEADPD
TH_0952|M.thermoresistible__bu --------MAVEERVAVITVNDPERRNAVT-FEMSEALRAAVARAEADEA
MMAR_3510|M.marinum_M --MNTALDITTNGPIRTWTINLPDVGNAITGKDFIAAFEAAVDDANIDTS
MLBr_02402|M.leprae_Br4923 -MKYDTILVDGYQRVGIITLNRPQALNALN-SQMMNEITNAAKELDIDPD
MUL_0210|M.ulcerans_Agy99 -MSYETILVERDQRVGIITLNRPQALNALN-SQVMNEVTSAAAELDNDPG
MAB_0834|M.abscessus_ATCC_1997 ----MIRVEPREHGILVVTIDRPERRNALD-PQTVAELHAVIESIDGDPK
: *:: *: **: : . . : *
Mb2511|M.bovis_AF2122/97 VHAVVVTGAGKAFCAGADLSALGAGVGDPA-----------EPRLLR---
Rv2486|M.tuberculosis_H37Rv VHAVVVTGAGKAFCAGADLSALGAGVGDPA-----------EPRLLR---
MAV_1678|M.avium_104 VHAVVITGAGKAFCAGADLSALGAAGGGSA-----------ETGLQQ---
Mflv_2557|M.gilvum_PYR-GCK VHAVIVTGAGKAFCAGADLTALGAAT---------------EDGLRV---
Mvan_4083|M.vanbaalenii_PYR-1 VHAVIVTGAGKAFCAGADLTALGAAT---------------EDGLRV---
MSMEG_4709|M.smegmatis_MC2_155 VHAVVVTGAGKAFCAGADLAALGTAT---------------EDGLRK---
TH_0952|M.thermoresistible__bu VHAVVVTGAGRAFCAGADLAALRTAT---------------EDDLRR---
MMAR_3510|M.marinum_M VRAVILTGAGKIFSGGGNVKEMANRDGMFG-----------LDALEQRQA
MLBr_02402|M.leprae_Br4923 VGAILITGSPKVFAAGADIKEMAS--------------------LTFTDA
MUL_0210|M.ulcerans_Agy99 IGAIIITGSAKAFAAGADIKEMAD--------------------LTFSEA
MAB_0834|M.abscessus_ATCC_1997 VRVVVLTAVGASFCAGADLKSLPSDFTSAGVTSTAALLAATDSELVRTLA
: .:::*. *..*.:: : *
Mb2511|M.bovis_AF2122/97 ----LYDGFMAVSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFD
Rv2486|M.tuberculosis_H37Rv ----LYDGFMAVSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFD
MAV_1678|M.avium_104 ----LYDGFMAIGSCRLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFD
Mflv_2557|M.gilvum_PYR-GCK ----IYDGFLAVAQCSLPTIAAVNGAAVGAGLNLALAADVRIAGPHAMFD
Mvan_4083|M.vanbaalenii_PYR-1 ----IYDGFLAVAECNLPTIAAVNGPAVGAGLNLALAADVRIAGPAALFD
MSMEG_4709|M.smegmatis_MC2_155 ----IYDGFLAVAHCTLPTIAAVNGAAVGAGLNLALAADVRIAGPHALFD
TH_0952|M.thermoresistible__bu ----LYDGFIAVARCTLPTVAAVNGPAVGAGLNLALAADVRIAGPTAVFD
MMAR_3510|M.marinum_M YTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRASFA
MLBr_02402|M.leprae_Br4923 FDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFG
MUL_0210|M.ulcerans_Agy99 FDADFFAAWGKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFG
MAB_0834|M.abscessus_ATCC_1997 AQELMASLFERIHRMRQPVIAAVNGHAIGGGFALALACDIRFASPAASFG
: : * :.*: * *:*.* :*: .*: :*. * *
Mb2511|M.bovis_AF2122/97 ARFQKLGLHPG-GGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLAL
Rv2486|M.tuberculosis_H37Rv ARFQKLGLHPG-GGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLAL
MAV_1678|M.avium_104 PRFQQLGLHPG-GGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGLAL
Mflv_2557|M.gilvum_PYR-GCK PRFQKLGIHPG-GGATWMLQRITGPQAARAALLFGMRFDADAAVRHGLAL
Mvan_4083|M.vanbaalenii_PYR-1 PRFQKLGIHPG-GGATWMLQRAIGPQAARAALLFGMRFDAESAVRHGLAL
MSMEG_4709|M.smegmatis_MC2_155 PRFQKLGIHPG-GGATWMLQRAAGPEVARAALLFGMRFDAEAAVRHGLAL
TH_0952|M.thermoresistible__bu PRFQKLGIHPG-GGATWMLQRAIGPQAARASLLFGLGFDAEAAVRSGLAL
MMAR_3510|M.marinum_M ESFVALGIIPG-DGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMVS
MLBr_02402|M.leprae_Br4923 QPEIKLGVLPG-MGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVS
MUL_0210|M.ulcerans_Agy99 QPEIKLGVLPG-MGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVS
MAB_0834|M.abscessus_ATCC_1997 AVFIRHGVSNCDMGTSYHLPRLVGAARAAELMLTGRVFDAQEAYRMGLVF
*: * : * * * * * * :** * . *:.
Mb2511|M.bovis_AF2122/97 MVA--DDPVTAALELAAGPAAAPREVVLASKATMRATASPGSLDLEQHEL
Rv2486|M.tuberculosis_H37Rv MVA--DDPVTAALELAAGPAAAPREVVLASKATMRATASPGSLDLEQHEL
MAV_1678|M.avium_104 SVA--DDPVAAALELAAGPAAAPREVVLATKATMRATISLGSLDNEQHQH
Mflv_2557|M.gilvum_PYR-GCK EVA--DDPVARARELAAGPAGAPRDVVVATKASMRATAHPGTDDLEQHRL
Mvan_4083|M.vanbaalenii_PYR-1 EVA--DDPVAAARELAAGPASAPRDVVVSTKASMRATYNPGISDLHQHHM
MSMEG_4709|M.smegmatis_MC2_155 TVA--DDPLAAARELASGPASAPREVVLATKASMRATANPGVIDTDQHRA
TH_0952|M.thermoresistible__bu KIA--EDPVAAARELAAGPAAAPRDVVVATKASMRATANPGVPDTEQHMR
MMAR_3510|M.marinum_M RVVPHDDLLPQAQELAERIVKNPAHALRMAKRLLQESR------VGSLES
MLBr_02402|M.leprae_Br4923 RVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFES------TLAE
MUL_0210|M.ulcerans_Agy99 RVVPADDLLTEAKAVATTISQMSRSAARMAKEAVNRTFEA------TLAE
MAB_0834|M.abscessus_ATCC_1997 DVVPAEELLDAALSKAREIAVHSPLAVWMTKETMWQTVDAP-----SLRH
:. :: : * * . . :* : :
Mb2511|M.bovis_AF2122/97 AKRLELGPQAKSVQSPEFAARLAAAQHR--------
Rv2486|M.tuberculosis_H37Rv AKRLELGPQAKSVQSPEFAARLAAAQHR--------
MAV_1678|M.avium_104 AMRTELGPQAHSIQSPEFAQRLAAAQRK--------
Mflv_2557|M.gilvum_PYR-GCK AVDIEIVPQATSIESPEFAARLAAAKRR--------
Mvan_4083|M.vanbaalenii_PYR-1 AVDIEIGPQARSIESPEFAARLAAAQRR--------
MSMEG_4709|M.smegmatis_MC2_155 AVDIELGPQARSIESPEFAARLAARRK---------
TH_0952|M.thermoresistible__bu AVDTELPPQAASIAAPAFAERIAAALRR--------
MMAR_3510|M.marinum_M TLGMAAAMQPLAHRDPEHQQRIAKWRTR--------
MLBr_02402|M.leprae_Br4923 GLLHERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR
MUL_0210|M.ulcerans_Agy99 GLLYERRLIHSAFATADQSEGMAAFIEKRPPNFTHR
MAB_0834|M.abscessus_ATCC_1997 ALDLENRTQVMCTATGELRRSFDAFREGRG------
: