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TAELVLTADHDGVRVITLNRPAARNALSRDLIRASYAALTAADADESVRAVVLTGADPAFCAGVDLKEAA RDGLSYFAEFRSQSCIAAVARMRTPVVGAINGATFTGGLEMALGCDFLIASERAVFADTHARVGILPGGG MTAYLPQVVGAAMARRLSMTGEVVDAARAERIGLVTEVVVHDRLLDRAVELATQIAEVPRPTMRSLKEIY TTGAAAVTDPALAAEEEIAFAQHRDLDGLGDRFSAVAQRNKEQIRPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1871 | - | - | 100% (258) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_2320 | - | 1e-48 | 46.12% (258) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | 7e-35 | 37.02% (235) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2855 | echA16 | 7e-50 | 45.00% (260) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4495 | - | 1e-125 | 88.63% (255) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv2831 | echA16 | 3e-50 | 45.00% (260) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-34 | 38.39% (211) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3124 | - | 9e-52 | 46.69% (257) | enoyl-CoA hydratase |
| M. marinum M | MMAR_1903 | echA16_2 | 9e-49 | 43.85% (260) | enoyl-CoA hydratase, EchA16_2 |
| M. avium 104 | MAV_3689 | - | 8e-50 | 45.70% (256) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2047 | - | 1e-100 | 73.81% (252) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3880 | - | 1e-101 | 71.88% (256) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 2e-34 | 36.91% (233) | enoyl-CoA hydratase, EchA8_5 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1871|M.vanbaalenii_PYR-1 MTAE-LVLTADHDGVRVITLNRPAARNALS-RDLIRASYAALTAADADES
Mflv_4495|M.gilvum_PYR-GCK MTED-LVLTADHDGVRVITLNRPAARNALS-RDLIRATYTALTSADDDDA
MSMEG_2047|M.smegmatis_MC2_155 MS---IVLTADHGAVRVLTMNRPEARNALG-SELIEALFTALQDADDDES
TH_3880|M.thermoresistible__bu MTSDRVVSRTDHGPVRLLTMNRPESRNALS-RNLIRELYTAFEEADQDAS
Mb2855|M.bovis_AF2122/97 MTDD-ILLIDTDERVRTLTLNRPQSRNALS-AALRDRFFAALADAEADDD
Rv2831|M.tuberculosis_H37Rv MTDD-ILLIDTDERVRTLTLNRPQSRNALS-AALRDRFFAALADAEADDD
MMAR_1903|M.marinum_M MTNE-ILLIDTAERVLTLTLNRPQSRNALS-AALRDQFFAALAAAETDDD
MAV_3689|M.avium_104 MTDE-ILLSNTEERVRTLTLNRPQARNALS-AALRDRFFGALADAETDDD
MAB_3124|M.abscessus_ATCC_1997 MTEP-ILLTHTEDRICTITLNRPQARNALS-TALGEEIVKAVTAADADEN
MLBr_02402|M.leprae_Br4923 MKYD-TILVDGYQRVGIITLNRPQALNALN-SQMMNEITNAAKELDIDPD
MUL_2758|M.ulcerans_Agy99 --MNTALDITTNGPIRTWTINLPDVGNAITGRDFIAAFEAAVDDANIDTS
: : *:* * **: : * : *
Mvan_1871|M.vanbaalenii_PYR-1 VRAVVLTGADPAFCAGVDLKEAAR----DGLSYFAEFRSQSC-----IAA
Mflv_4495|M.gilvum_PYR-GCK VRAVVLTGADPAFCAGVDLKEAAR----DGLSYFAEFRTQSC-----IAA
MSMEG_2047|M.smegmatis_MC2_155 VRAVVLTGADPAFCAGVDLKQAQT----LGMDYFARFQTHNC-----IAK
TH_3880|M.thermoresistible__bu VRAMVLTGADPAFCAGVDLKEAQR----DGMTYFDEFRTHDC-----ITK
Mb2855|M.bovis_AF2122/97 IDVVILTGADPVFCAGLDLKELA------GQTALPDISP----------R
Rv2831|M.tuberculosis_H37Rv IDVVILTGADPVFCAGLDLKELA------GQTALPDISP----------R
MMAR_1903|M.marinum_M VDVIILTGADPVFCAGLDLKELG------GQSALPDISP----------R
MAV_3689|M.avium_104 VDVVIITGADPVFCAGLDLKELG------GSSALPDISP----------R
MAB_3124|M.abscessus_ATCC_1997 VDVMILTAADPVFCAGVDLKELG------SGDRAESLDP----------W
MLBr_02402|M.leprae_Br4923 VGAILITGSPKVFAAGADIKEMAS----LTFTDAFDADFFSA-----WGK
MUL_2758|M.ulcerans_Agy99 VRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQRQAYTDGIQRIPRA
: .:::*.: *..* ::*:
Mvan_1871|M.vanbaalenii_PYR-1 VARMRTPVVGAINGATFTGGLEMALGCDFLIASERAVFADTHARVGILPG
Mflv_4495|M.gilvum_PYR-GCK VAAMRTPVVGAINGATFTGGLEMALGCDFMIASERAVFADTHARVGILPG
MSMEG_2047|M.smegmatis_MC2_155 TGQMATPIIGAINGATFTGGLEMALGCDFLIASERAVFADTHARVGILPG
TH_3880|M.thermoresistible__bu PAELRTPIIAAVNGPTFTGGLEMALGCDFLIASDRAVFADTHARVGILPG
Mb2855|M.bovis_AF2122/97 WPAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHARVGLLPT
Rv2831|M.tuberculosis_H37Rv WPAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHARVGLLPT
MMAR_1903|M.marinum_M WPALTKPVIGAINGAAVTGGLELALYCDILIASEQARFADTHARVGLLPT
MAV_3689|M.avium_104 WPALTKPVIGAINGAAVTGGLELALYCDILIASENARFADTHARVGLLPT
MAB_3124|M.abscessus_ATCC_1997 WPELSKPVIGAINGAAVTGGLELALACDILIASEKARFADTHARVGILPT
MLBr_02402|M.leprae_Br4923 LAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPG
MUL_2758|M.ulcerans_Agy99 LARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRASFAESFVALGIIPG
: *::.*: * :. .* ::*: **: **:: * *.:. :*::*
Mvan_1871|M.vanbaalenii_PYR-1 GGMTAYLPQVVGAAMARRLSMTGEVVDAARAERIGLVTEVVVHDRLLDRA
Mflv_4495|M.gilvum_PYR-GCK GGMTARLPQLVGAAMARRLSMTGEVVDAARAERIGLVTEVVAHQHLLQRA
MSMEG_2047|M.smegmatis_MC2_155 GGMTARLPQVVGAAMARRLSMTGEVVDASRAERLGLVTEVVAHEQLLVRA
TH_3880|M.thermoresistible__bu GGMTARLPQVVGAAMARRMSMTGEVIDAARAERLGLVTEVVEHDRLLDRA
Mb2855|M.bovis_AF2122/97 WGLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAHDQLLPTA
Rv2831|M.tuberculosis_H37Rv WGLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAHDQLLPTA
MMAR_1903|M.marinum_M WGLSVRLPQKVGVGLARRMSLTGDYLSATDALRAGLVTEVVEHQQLLPAA
MAV_3689|M.avium_104 WGLSVRLPQKVGIGLARRMSLTGDYLSAADALRAGLVTEVVPHDQLLGAA
MAB_3124|M.abscessus_ATCC_1997 WGLTTLLPLSVGRGLARRMSLTGDYLSAEDALRAGLVTEVVAHNELLPAA
MLBr_02402|M.leprae_Br4923 MGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEA
MUL_2758|M.ulcerans_Agy99 DGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMVSRVVPHGDLLPQA
* : * :* * : :** :.* * . *:*:.** ** *
Mvan_1871|M.vanbaalenii_PYR-1 VELATQIAEVPRPTMRSLKEIYTTGAAAVTDPALAAEEEIAFAQHRD---
Mflv_4495|M.gilvum_PYR-GCK IDLAHQIAEVPRPTMRGLKEIYTAGASAVVDPALAAEERIAFAQHRD---
MSMEG_2047|M.smegmatis_MC2_155 LELAQQIAEVPGPIMSGLKEIYTLGADPVITPALDAEQQIAGTQQRD---
TH_3880|M.thermoresistible__bu LELAGQIAEVPADTMAGLKEIYARGIGPVIAPALAAEQDIAAAQLRD---
Mb2855|M.bovis_AF2122/97 RRVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQFCTS---
Rv2831|M.tuberculosis_H37Rv RRVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQFRTS---
MMAR_1903|M.marinum_M RQVAASIVGNNQNAVRALLASYHRIDESSTAQGLWLEATAAREFRTS---
MAV_3689|M.avium_104 RAVAASIVGNNQNAVRALLTSYHRIDDAQTSAGLWQEAMAARQFRTS---
MAB_3124|M.abscessus_ATCC_1997 KRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHRWIDQNSI
MLBr_02402|M.leprae_Br4923 KAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVT---
MUL_2758|M.ulcerans_Agy99 QELAERIVKNPAHALRMAKRLLQESRVGSLESTLGMAAAMQPLAHRDPEH
:* * *
Mvan_1871|M.vanbaalenii_PYR-1 LDGLGDRFSAVAQRNKEQIRPS
Mflv_4495|M.gilvum_PYR-GCK LEGLGDRFSAVSQRNRDQIGGA
MSMEG_2047|M.smegmatis_MC2_155 FAGLGDRYRAVAERNHAQIQR-
TH_3880|M.thermoresistible__bu FGGLGERFMAVSQRNRQQLG--
Mb2855|M.bovis_AF2122/97 GDTIAANREAVLQRGRAQVR--
Rv2831|M.tuberculosis_H37Rv GDTIAANREAVLQRGRAQVR--
MMAR_1903|M.marinum_M GDDIAANREAVLNRGRSQVR--
MAV_3689|M.avium_104 GDDIAANREAVLARGRSQVR--
MAB_3124|M.abscessus_ATCC_1997 AEGVEARRTAIMERGRSQNA--
MLBr_02402|M.leprae_Br4923 -DDQSEGMAAFIEKRAPQFTHR
MUL_2758|M.ulcerans_Agy99 QQRIAKWRTRIAKWRTR-----
.