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M. thermoresistible (build 8) TH_0952 (echA14)

annotation: PROBABLE ENOYL-CoA HYDRATASE ECHA14 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
coordinates: 1887667 - 1888401
length: 245

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0952 echA14 - 100% (245) PROBABLE ENOYL-CoA HYDRATASE ECHA14 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
M. thermoresistible (build 8) TH_0715 - 1e-26 74.03% (77) enoyl-CoA hydratase
M. thermoresistible (build 8) TH_3065 - 4e-26 32.40% (250) PUTATIVE enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2511 echA14 1e-93 70.56% (248) enoyl-CoA hydratase
M. gilvum PYR-GCK Mflv_2557 - 1e-103 77.05% (244) enoyl-CoA hydratase
M. tuberculosis H37Rv Rv2486 echA14 1e-93 70.56% (248) enoyl-CoA hydratase
M. leprae Br4923 MLBr_02402 - 4e-23 30.89% (246) enoyl-CoA hydratase
M. abscessus ATCC 19977 MAB_1185c - 5e-25 35.50% (200) enoyl-CoA hydratase
M. marinum M MMAR_2974 - 2e-25 33.47% (236) enoyl-CoA hydratase
M. avium 104 MAV_1678 - 3e-95 71.54% (246) enoyl-CoA hydratase
M. smegmatis MC2 155 MSMEG_4709 - 1e-105 80.08% (236) enoyl-CoA hydratase
M. ulcerans Agy99 MUL_2758 echA8_5 2e-24 37.57% (189) enoyl-CoA hydratase, EchA8_5
M. vanbaalenii PYR-1 Mvan_4083 - 1e-105 78.51% (242) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2557|M.gilvum_PYR-GCK          ----MSELVLMQVTDRVALITINDPDRRNAVT-AEISAALRAAVSAAEAD
Mvan_4083|M.vanbaalenii_PYR-1       ----MSELVLTQVEDRVALITINDPDRRNAVT-AEISAALRAAVEAAEAD
MSMEG_4709|M.smegmatis_MC2_155      ----MADSVLVETSDRIAVITVNDPDRRNAVT-FEMSAALRSAVEAAEAD
TH_0952|M.thermoresistible__bu      ----------MAVEERVAVITVNDPERRNAVT-FEMSEALRAAVARAEAD
Mb2511|M.bovis_AF2122/97            --MAQYDPVLLSVDKHVALITVNDPDRRNAVT-DEMSAQLRAAIQRAEGD
Rv2486|M.tuberculosis_H37Rv         --MAQYDPVLLSVDKHVALITVNDPDRRNAVT-DEMSAQLRAAIQRAEGD
MAV_1678|M.avium_104                --MAQSNLVLLDIENHVALITVNDPDRRNAVT-AEMSGRLREAVERVEAD
MUL_2758|M.ulcerans_Agy99           ----MNTALDITTNGPIRTWTINLPDVGNAITGRDFIAAFEAAVDDANID
MLBr_02402|M.leprae_Br4923          ---MKYDTILVDGYQRVGIITLNRPQALNALN-SQMMNEITNAAKELDID
MAB_1185c|M.abscessus_ATCC_199      MTSHNFETILTERIDRVAVITLNRPKALNALN-SQVMNEVTTAAAEFDAD
MMAR_2974|M.marinum_M               -----MTDLTVSVTDGIAILTLNRPQRRNAYT-AEMGLSLSSAYRQCDDD
                                                    :   *:* *.  ** .  :.   .  *    : *

Mflv_2557|M.gilvum_PYR-GCK          PDVHAVIVTGAGKAFCAGADLTALGAAT----EDGLRV-------IYDGF
Mvan_4083|M.vanbaalenii_PYR-1       TGVHAVIVTGAGKAFCAGADLTALGAAT----EDGLRV-------IYDGF
MSMEG_4709|M.smegmatis_MC2_155      PDVHAVVVTGAGKAFCAGADLAALGTAT----EDGLRK-------IYDGF
TH_0952|M.thermoresistible__bu      EAVHAVVVTGAGRAFCAGADLAALRTAT----EDDLRR-------LYDGF
Mb2511|M.bovis_AF2122/97            PDVHAVVVTGAGKAFCAGADLSALGAGVGDPAEPRLLR-------LYDGF
Rv2486|M.tuberculosis_H37Rv         PDVHAVVVTGAGKAFCAGADLSALGAGVGDPAEPRLLR-------LYDGF
MAV_1678|M.avium_104                SDVHAVVITGAGKAFCAGADLSALGAAGGGSAETGLQQ-------LYDGF
MUL_2758|M.ulcerans_Agy99           TSVRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQRQAYTDGIQRIP
MLBr_02402|M.leprae_Br4923          PDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFF-------SAWGK
MAB_1185c|M.abscessus_ATCC_199      HGIGAIIITGSEKAFAAGADIKEMSEQSFSDMFGSDFF-------SAWGK
MMAR_2974|M.marinum_M               DAVRAIVVTGAGDAFCAGADFSGDTNPFDAPDGGGGFT-------AAPID
                                      : *:::**:   *..*.:.                             

Mflv_2557|M.gilvum_PYR-GCK          LAVAQCSLPTIAAVNGAAVGAGLNLALAADVRIAGPHAMFDPRFQKLGIH
Mvan_4083|M.vanbaalenii_PYR-1       LAVAECNLPTIAAVNGPAVGAGLNLALAADVRIAGPAALFDPRFQKLGIH
MSMEG_4709|M.smegmatis_MC2_155      LAVAHCTLPTIAAVNGAAVGAGLNLALAADVRIAGPHALFDPRFQKLGIH
TH_0952|M.thermoresistible__bu      IAVARCTLPTVAAVNGPAVGAGLNLALAADVRIAGPTAVFDPRFQKLGIH
Mb2511|M.bovis_AF2122/97            MAVSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDARFQKLGLH
Rv2486|M.tuberculosis_H37Rv         MAVSSCNLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDARFQKLGLH
MAV_1678|M.avium_104                MAIGSCRLPTIAAVNGAAVGAGLNLALAADVRIAGPAALFDPRFQQLGLH
MUL_2758|M.ulcerans_Agy99           RALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRASFAESFVALGII
MLBr_02402|M.leprae_Br4923          LA--AVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVL
MAB_1185c|M.abscessus_ATCC_199      LG--AVRTPTIAAVSGYALGGGCELAMMCDVIIAAENATFGQPEIKLGVL
MMAR_2974|M.marinum_M               PAAFELRTPVIAAVNGHAIGIGLTIALQADIRIMAEFAKYAVAQVRRGVI
                                     .      * :.*: * *:* *  :*: .*: * .  * :       *: 

Mflv_2557|M.gilvum_PYR-GCK          PGGGATWMLQRITGPQAARAALLFGMRFDADAAVRHGLALEVA--DDPVA
Mvan_4083|M.vanbaalenii_PYR-1       PGGGATWMLQRAIGPQAARAALLFGMRFDAESAVRHGLALEVA--DDPVA
MSMEG_4709|M.smegmatis_MC2_155      PGGGATWMLQRAAGPEVARAALLFGMRFDAEAAVRHGLALTVA--DDPLA
TH_0952|M.thermoresistible__bu      PGGGATWMLQRAIGPQAARASLLFGLGFDAEAAVRSGLALKIA--EDPVA
Mb2511|M.bovis_AF2122/97            PGGGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLALMVA--DDPVT
Rv2486|M.tuberculosis_H37Rv         PGGGATWMLQRAVGPQVARAALLFGMCFDAESAVRHGLALMVA--DDPVT
MAV_1678|M.avium_104                PGGGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGLALSVA--DDPVA
MUL_2758|M.ulcerans_Agy99           PGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMVSRVVPHGDLLP
MLBr_02402|M.leprae_Br4923          PGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLP
MAB_1185c|M.abscessus_ATCC_199      PGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLVSRVVATESLLD
MMAR_2974|M.marinum_M               ADCMSHWTLPHLVGSAAAADIHLTGRTFDGAEALAMGIATRTLPGPHVLG
                                    ..  .   * :  *   *    * *  :*.  *   *:.         : 

Mflv_2557|M.gilvum_PYR-GCK          RARELAAGPAGAPRDVVVATKASMRATAHPGTDDLEQHRLAVDIEIVPQA
Mvan_4083|M.vanbaalenii_PYR-1       AARELAAGPASAPRDVVVSTKASMRATYNPGISDLHQHHMAVDIEIGPQA
MSMEG_4709|M.smegmatis_MC2_155      AARELASGPASAPREVVLATKASMRATANPGVIDTDQHRAAVDIELGPQA
TH_0952|M.thermoresistible__bu      AARELAAGPAAAPRDVVVATKASMRATANPGVPDTEQHMRAVDTELPPQA
Mb2511|M.bovis_AF2122/97            AALELAAGPAAAPREVVLASKATMRATASPGSLDLEQHELAKRLELGPQA
Rv2486|M.tuberculosis_H37Rv         AALELAAGPAAAPREVVLASKATMRATASPGSLDLEQHELAKRLELGPQA
MAV_1678|M.avium_104                AALELAAGPAAAPREVVLATKATMRATISLGSLDNEQHQHAMRTELGPQA
MUL_2758|M.ulcerans_Agy99           QAQELAERIVKNPAHALRMAKRLLQESR-VGSLESTLGMAAAMQPLAHRD
MLBr_02402|M.leprae_Br4923          EAKAVATTISQMSRSATRMAKEAVNRSFES---TLAEGLLHERRLFHSTF
MAB_1185c|M.abscessus_ATCC_199      EAKAVAKTISEMSLSASMMAKEAVNRAFES---SLAEGLLFERRIFHSAF
MMAR_2974|M.marinum_M               HAMAVARDIAANTAPMSVALSKRLLWDTLINGYTPRQVAELETQLHRRVM
                                     *  :*      .       .  :                          

Mflv_2557|M.gilvum_PYR-GCK          TSIES----PEFAARLAAAKRR------------------
Mvan_4083|M.vanbaalenii_PYR-1       RSIES----PEFAARLAAAQRR------------------
MSMEG_4709|M.smegmatis_MC2_155      RSIES----PEFAARLAARRK-------------------
TH_0952|M.thermoresistible__bu      ASIAA----PAFAERIAAALRR------------------
Mb2511|M.bovis_AF2122/97            KSVQS----PEFAARLAAAQHR------------------
Rv2486|M.tuberculosis_H37Rv         KSVQS----PEFAARLAAAQHR------------------
MAV_1678|M.avium_104                HSIQS----PEFAQRLAAAQRK------------------
MUL_2758|M.ulcerans_Agy99           PEHQQR--IAKWRTRIAKWRTR------------------
MLBr_02402|M.leprae_Br4923          VTDDQSEGMAAFIEKRAPQFTHR-----------------
MAB_1185c|M.abscessus_ATCC_199      GTADQSEGMAAFVEKRPANFIHR-----------------
MMAR_2974|M.marinum_M               GSADAREGVEAFLQHRAPRWSASVSSAWKPLPAPDHREQP
                                               :  : .

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0952	echA14	-	100% (245)	PROBABLE ENOYL-CoA HYDRATASE ECHA14 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
M. thermoresistible (build 8)	TH_0715	-	1e-26	74.03% (77)	enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_3065	-	4e-26	32.40% (250)	PUTATIVE enoyl-CoA hydratase