For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TPTSPHRSERQPLDTASPLAVHTVDAVTTWTINLPHVGNAITGTDFIAAFESAVDTANSDVAVRAVILTG AGKIFSAGGNVKEMADRQGMFGLDAIAQRHAYVDGIQRIPRALARLEVPLIAAVNGPAIGAGCDLAAMCD IRVASERASFAESFVQIGLVPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGLVSRVVAHDELLT AAGELAARIAKNPPHTLRMAKRLLQESRTGVLESTLGMAAAMQPLAHRDPEHAARISRWRSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2877 | - | - | 100% (273) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1871 | - | 8e-35 | 37.02% (235) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4083 | - | 3e-30 | 37.30% (252) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 4e-31 | 37.68% (207) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4495 | - | 5e-33 | 36.71% (237) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 4e-31 | 37.68% (207) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 3e-31 | 38.43% (216) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1185c | - | 9e-31 | 36.57% (216) | enoyl-CoA hydratase |
| M. marinum M | MMAR_3510 | echA8_5 | 1e-115 | 80.63% (253) | enoyl-CoA hydratase, EchA8_5 |
| M. avium 104 | MAV_1939 | - | 6e-35 | 36.51% (241) | enoyl-CoA hydratase/isomerase |
| M. smegmatis MC2 155 | MSMEG_2880 | - | 1e-116 | 80.69% (259) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3045 | - | 8e-34 | 41.35% (208) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2758 | echA8_5 | 1e-114 | 80.24% (253) | enoyl-CoA hydratase, EchA8_5 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2877|M.vanbaalenii_PYR-1 MTPTSPHRSERQPLDTASPLAVHTVDAVTTWTINLPHVGNAITGTDFIAA
MSMEG_2880|M.smegmatis_MC2_155 -------------MTASEPLLIGASGAAQMWTINLPQVGNAITGSDFIRA
MMAR_3510|M.marinum_M ---------------MNTALDITTNGPIRTWTINLPDVGNAITGKDFIAA
MUL_2758|M.ulcerans_Agy99 ---------------MNTALDITTNGPIRTWTINLPDVGNAITGRDFIAA
TH_3045|M.thermoresistible__bu -----------VKYDLPDVMTVRADGPIRTVTLDRAADLNSVD-ADLHWA
MAV_1939|M.avium_104 -------------------MLSDLTDGIMTITLNRPDAANAVR-PDDRDT
Mb1099c|M.bovis_AF2122/97 --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
Rv1070c|M.tuberculosis_H37Rv --------------MTYETILVERDQRVGIITLNRPQALNALN-SQVMNE
MLBr_02402|M.leprae_Br4923 --------------MKYDTILVDGYQRVGIITLNRPQALNALN-SQMMNE
MAB_1185c|M.abscessus_ATCC_199 -----------MTSHNFETILTERIDRVAVITLNRPKALNALN-SQVMNE
Mflv_4495|M.gilvum_PYR-GCK --------------MTEDLVLTADHDGVRVITLNRPAARNALS-RDLIRA
: *:: . *:: :
Mvan_2877|M.vanbaalenii_PYR-1 FESAVDTANSDVAVRAVILTGAGKIFSAGGNVKEMADRQGMFGLDAIAQR
MSMEG_2880|M.smegmatis_MC2_155 FEDAVDAANRDPTVGAVILTGSGKIFSAGGNVKEMADREGMFGLDAIDQR
MMAR_3510|M.marinum_M FEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQR
MUL_2758|M.ulcerans_Agy99 FEAAVDDANIDTSVRAVILTGAGKIFSGGGNVKEMANRDGMFGLDALEQR
TH_3045|M.thermoresistible__bu LANVWRQLAADTDARVVILTGAGRAFSAGGDLDWITS----FLTDQVARD
MAV_1939|M.avium_104 LIALLEAADADEKVRVVVLRANGKHFCSGADVTALADRRGRGEKRVLEPT
Mb1099c|M.bovis_AF2122/97 VTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMAD---------LTFA
Rv1070c|M.tuberculosis_H37Rv VTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMAD---------LTFA
MLBr_02402|M.leprae_Br4923 ITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMAS---------LTFT
MAB_1185c|M.abscessus_ATCC_199 VTTAAAEFDADHGIGAIIITGSEKAFAAGADIKEMSE---------QSFS
Mflv_4495|M.gilvum_PYR-GCK TYTALTSADDDDAVRAVVLTGADPAFCAGVDLKEAAR---------DGLS
* .::: . *..* :: :
Mvan_2877|M.vanbaalenii_PYR-1 HAYVDGIQRIPRALARLEVPLIAAVNGPAIGAGCDLAAMCDIRVASERAS
MSMEG_2880|M.smegmatis_MC2_155 FAYVDGIQRIPRALARLEVPIIAAVNGAAVGAGFDLAMMCDIRVASERAS
MMAR_3510|M.marinum_M QAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRAS
MUL_2758|M.ulcerans_Agy99 QAYTDGIQRIPRALARLEVPLIGAINGAAIGAGCDLAMMCDIRIASQRAS
TH_3045|M.thermoresistible__bu ESIREGAQIIEEMLR-FPLPVIAAVNGPAVGLGCSVAVLCDIVLIAENAY
MAV_1939|M.avium_104 RRIMNGAQKLVASVLDCNKPVIAAVHGAATGLGAHIVYASDLVIATENAY
Mb1099c|M.bovis_AF2122/97 DAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAK
Rv1070c|M.tuberculosis_H37Rv DAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAK
MLBr_02402|M.leprae_Br4923 DAFDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAK
MAB_1185c|M.abscessus_ATCC_199 DMFGSDFFSAWGKLGAVRTPTIAAVSGYALGGGCELAMMCDVIIAAENAT
Mflv_4495|M.gilvum_PYR-GCK YFAEFRTQSCIAAVAAMRTPVVGAINGATFTGGLEMALGCDFMIASERAV
: * :.*: * : * :. .*. : :: *
Mvan_2877|M.vanbaalenii_PYR-1 FAESFVQIGLVPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGLV
MSMEG_2880|M.smegmatis_MC2_155 FAESFVQLGLVPGDGGTWFLQRAIGYERAAEMTFTGDRVDAATALDWGLV
MMAR_3510|M.marinum_M FAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMV
MUL_2758|M.ulcerans_Agy99 FAESFVALGIIPGDGGTWFLQRAIGYERAAEMTLTGDRIDAATALEWGMV
TH_3045|M.thermoresistible__bu LADPHVAVGLVAGDGGAAMWPLLTLVLRSREYLFTGDRIPAATAVELGLA
MAV_1939|M.avium_104 FAESFVKRGLVVDGGGCYLLPRRIGMQKAKEMAFFGERLSAAEALALGLV
Mb1099c|M.bovis_AF2122/97 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLV
Rv1070c|M.tuberculosis_H37Rv FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLV
MLBr_02402|M.leprae_Br4923 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLV
MAB_1185c|M.abscessus_ATCC_199 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLV
Mflv_4495|M.gilvum_PYR-GCK FADTHARVGILPGGGMTARLPQLVGAAMARRLSMTGEVVDAARAERIGLV
:.:. *:: . * : : * : ** * *:.
Mvan_2877|M.vanbaalenii_PYR-1 SRVVAHDELLTAAGELAARIAKNPPHTLRMAKRLLQESRTGVLESTLGMA
MSMEG_2880|M.smegmatis_MC2_155 SRVVPHDELLSAAQDLAARIVRNPARALRMAKRLLQESRTGVLESTLGMA
MMAR_3510|M.marinum_M SRVVPHDDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGMA
MUL_2758|M.ulcerans_Agy99 SRVVPHGDLLPQAQELAERIVKNPAHALRMAKRLLQESRVGSLESTLGMA
TH_3045|M.thermoresistible__bu SRTVPADDLLPEAIRLAERLAAQPAEALRGTKRIVNMYLSQALAGPLQAG
MAV_1939|M.avium_104 NRVVGADEFDAAVADFAGRLAQAPTSAIAFTKRLLNDSPDTDRSGAFVAE
Mb1099c|M.bovis_AF2122/97 SRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYE
Rv1070c|M.tuberculosis_H37Rv SRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYE
MLBr_02402|M.leprae_Br4923 SRVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHE
MAB_1185c|M.abscessus_ATCC_199 SRVVATESLLDEAKAVAKTISEMSLSASMMAKEAVNRAFESSLAEGLLFE
Mflv_4495|M.gilvum_PYR-GCK TEVVAHQHLLQRAIDLAHQIAEVPRPTMRGLKEIYTAGASAVVDPALAAE
...* : . * : . : *. :
Mvan_2877|M.vanbaalenii_PYR-1 AAMQPLAHRDPEHAARISRWRSS---------
MSMEG_2880|M.smegmatis_MC2_155 AAMQPLAHHDGEHARRIEKWRSV---------
MMAR_3510|M.marinum_M AAMQPLAHRDPEHQQRIAKWRTR---------
MUL_2758|M.ulcerans_Agy99 AAMQPLAHRDPEHQQRIAKWRTRIAKWRTR--
TH_3045|M.thermoresistible__bu FAAEVATMRTAEHRDRLLALRERTR-------
MAV_1939|M.avium_104 AMAQEIQSYAHDSKEGVQAFVEKRPTEFTGW-
Mb1099c|M.bovis_AF2122/97 RRLFHSAFATEDQSEGMAAFIEKRAPQFTHR-
Rv1070c|M.tuberculosis_H37Rv RRLFHSAFATEDQSEGMAAFIEKRAPQFTHR-
MLBr_02402|M.leprae_Br4923 RRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR-
MAB_1185c|M.abscessus_ATCC_199 RRIFHSAFGTADQSEGMAAFVEKRPANFIHR-
Mflv_4495|M.gilvum_PYR-GCK ERIAFAQHRDLEGLGDRFSAVSQRNRDQIGGA
: