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HLVDGQRDPAASFPLAQAVDDQAERRRANRAVAVSAAGLGLTGLIELAIALVSGSVALLGDALHNLSDVS TSLVVFVGFRSSRKSASERYPYGLERAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAA AVGIVGNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLGLCGVAKGWGWADGVAGLAVTGFIC HVGWEVSSEIGHRLLDGVDPGVVDTAEAVAAAIPGVVHAHARARWTGRTLRVEVEGWVDPAMSVADADDI GRRVADQLGARLPQMRSFSWAARGVPLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3313 | - | - | 100% (309) | hypothetical protein MMAR_3313 |
| M. marinum M | MMAR_2136 | - | 2e-12 | 28.71% (202) | metal transport protein |
| M. marinum M | MMAR_2137 | - | 2e-11 | 26.14% (241) | metal transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2050c | - | 9e-53 | 40.56% (286) | hypothetical protein Mb2050c |
| M. gilvum PYR-GCK | Mflv_1902 | - | 9e-58 | 42.71% (288) | cation diffusion facilitator family transporter |
| M. tuberculosis H37Rv | Rv2025c | - | 9e-53 | 40.56% (286) | hypothetical protein Rv2025c |
| M. leprae Br4923 | MLBr_00283 | - | 1e-05 | 27.57% (185) | putative cation-efflux transporter component |
| M. abscessus ATCC 19977 | MAB_0183c | - | 2e-13 | 25.93% (216) | putative cation transporter |
| M. avium 104 | MAV_3555 | - | 1e-137 | 78.62% (304) | cation efflux family protein |
| M. smegmatis MC2 155 | MSMEG_5604 | - | 5e-12 | 28.27% (191) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1241 | - | 5e-11 | 27.14% (199) | integral membrane protein |
| M. ulcerans Agy99 | MUL_1315 | - | 1e-150 | 98.88% (268) | hypothetical protein MUL_1315 |
| M. vanbaalenii PYR-1 | Mvan_3225 | - | 1e-56 | 42.31% (286) | cation diffusion facilitator family transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3313|M.marinum_M -----------------------------------MHLVDGQRDPAASFP
MUL_1315|M.ulcerans_Agy99 --------------------------------------------------
MAV_3555|M.avium_104 -----------------------------------MHVINGVRDPAASFP
Mb2050c|M.bovis_AF2122/97 MTHD---------------------HAHSR----GVPAMIKEIFAPHSHD
Rv2025c|M.tuberculosis_H37Rv MTHD---------------------HAHSR----GVPAMIKEIFAPHSHD
Mflv_1902|M.gilvum_PYR-GCK MTHD--AHAH---HDHGSGHDH-HPHSHSG-RGGKIGAALREVFAPHSHD
Mvan_3225|M.vanbaalenii_PYR-1 MSHATGAAAHPQNHDHPHHHDHDHPHDHGHPHGGKLRTVIREVFAPHSHD
MSMEG_5604|M.smegmatis_MC2_155 -------------------------------MRRPRWRRVRMRMMADTSK
TH_1241|M.thermoresistible__bu ---------------------------------------VTPSGAIGWRP
MAB_0183c|M.abscessus_ATCC_199 ------------------------------------------MAADAHEH
MLBr_00283|M.leprae_Br4923 ------------------------------------MQCMRKHAYIAHMG
MMAR_3313|M.marinum_M LAQAVDDQAERRRA-NRAVAVSAAGLGLTGLIELAIALVSGSVALLGDAL
MUL_1315|M.ulcerans_Agy99 ---------------------------MTGLIELAIALVSGSVALLGDAL
MAV_3555|M.avium_104 LDTATDDAGERRQA-NRAVAVSAAGLALTGLVELVIAVVSGSVALLGDAL
Mb2050c|M.bovis_AF2122/97 AADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTI
Rv2025c|M.tuberculosis_H37Rv AADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTI
Mflv_1902|M.gilvum_PYR-GCK ASDSIDSALESSAAGIRAVKISLLVLGVTAIAQIAIVAISGSVALLADTI
Mvan_3225|M.vanbaalenii_PYR-1 ASDSIDDALESSAAGIRAVKISLLVLGATTVGQLAIVAVSGSVALLADTI
MSMEG_5604|M.smegmatis_MC2_155 LTPTRRAVLARRIRMFVAATITYN--VIEAVVALTEGARVSSTALIGFGL
TH_1241|M.thermoresistible__bu LSESRRQQLARRIRVLVAATISYN--IIEAVVAIGEGARVSSTALIGFGL
MAB_0183c|M.abscessus_ATCC_199 GSGHSHGHGVNADADRKWLTIALILIGGFMAIEVVIGIIAQSLALISDAG
MLBr_00283|M.leprae_Br4923 SGGSYTPAEAAIYRMIRRMIVAAAILMVFFGVELTIALLINSITLLADAG
: * :* .
MMAR_3313|M.marinum_M HNLSDVSTSLVVFVGFRSSRKSASE-RYPYGLERAEDLAGIGVALVIWAS
MUL_1315|M.ulcerans_Agy99 HNLYDVSTSLVVFVGFRSSRKSASE-RYPYGLERAEDLAGIGVALVIWAS
MAV_3555|M.avium_104 HNLSDVSTSALVFVGFRASRKLPTE-RYPYGYERAEDLAGIGVALVIWGS
Mb2050c|M.bovis_AF2122/97 HNFADALTAVPLWIAFALGAKPATR-RYTYGFGRVEDLAGSFVVAMITMS
Rv2025c|M.tuberculosis_H37Rv HNFADALTAVPLWIAFALGAKPATR-RYTYGFGRVEDLAGSFVVAMITMS
Mflv_1902|M.gilvum_PYR-GCK HNFSDALTAIPLWIAFALSTKAATR-RYTYGFGRAEDLAGLFVVAMIALS
Mvan_3225|M.vanbaalenii_PYR-1 HNFSDAMTAIPLWIAFALGTRAATR-RYTYGFGRAEDIAGLFVVAMIALS
MSMEG_5604|M.smegmatis_MC2_155 DSVIEVSSAAAVAWQFAGRDP-----------EAREKVALRIVAFSFFGL
TH_1241|M.thermoresistible__bu DSAIEVSSAAAVAWQFAGRDP-----------EARERIALRVIAFSFFGL
MAB_0183c|M.abscessus_ATCC_199 HMLTDAASIVLALIAIRLSSRPARG-SYTFGLKRAEILSAQANGVTLFLL
MLBr_00283|M.leprae_Br4923 HMLTDVVAVFMGLAALVLAKHGHSAPNRPYSWHRAEVFTAMANAALLIGV
. :. : : * .: :
MMAR_3313|M.marinum_M AAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIVGNQLVARYKLVVGRRIQ
MUL_1315|M.ulcerans_Agy99 AAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIVGNQLVARYKLVVGRRIQ
MAV_3555|M.avium_104 AVVAGFESVTKLLRHGGTGHVGWGIAAAVVGVVGNQLVARYKLVVGRRIR
Mb2050c|M.bovis_AF2122/97 AIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIG
Rv2025c|M.tuberculosis_H37Rv AIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIG
Mflv_1902|M.gilvum_PYR-GCK AIIAGVESVRRLINPVPIEHVGWVALAGLVGFIGNELVALYRIRVGRRIS
Mvan_3225|M.vanbaalenii_PYR-1 AVVAGVESIRRLINPVAIEHVGWVAAAGLVGFLGNEIVAVYRIRVGRRIG
MSMEG_5604|M.smegmatis_MC2_155 ATYVAVDAIRSLLGIGEAQHSTIGIALAALSLVIMPVLSYAQRRAGRELG
TH_1241|M.thermoresistible__bu ATFVTVDAVRALLGMGESRPSTVGIVVAALSLLIMPVLSYAQRRAGRELG
MAB_0183c|M.abscessus_ATCC_199 AAFFIYEGIRRLITPPEVS--GLLVFITALAGIAVNVAATWCISKANRS-
MLBr_00283|M.leprae_Br4923 ATFILYEAIRRFKEAPYIP--GMPIVVAALAGLVTNFVVAPLLRP-HAED
* :.: : :. : .
MMAR_3313|M.marinum_M SSTMIADAKHSWLDALSSAGALLGLCG-VAKGWGWADGVAGLAVTGFICH
MUL_1315|M.ulcerans_Agy99 SSTMIADAKHSWLDALSSAGALLGLCG-VAMGWGWADGVAGLAVTGFICH
MAV_3555|M.avium_104 SATMVADAKHSWLDALSSAGAVLGLIG-VALGWGWADAVAGIVVTGFICH
Mb2050c|M.bovis_AF2122/97 SAALIADGLHARTDGFTSLAVLCSAGG-VALGFPLADPIVGLLITAAILA
Rv2025c|M.tuberculosis_H37Rv SAALIADGLHARTDGFTSLAVLCSAGG-VALGFPLADPIVGLLITAAILA
Mflv_1902|M.gilvum_PYR-GCK SAALVADGLHARTDGFTSLAVLLGAGG-VALGFPLADPVIGLVITVAILA
Mvan_3225|M.vanbaalenii_PYR-1 SAALVADGLHARTDGFTSLAVVLGAAG-AALGFPLADPIVGLLITVAILA
MSMEG_5604|M.smegmatis_MC2_155 SLSAVADSKQTLLCTYLSAVLLVGLLLNSIFGWSWADPIAGLVIAAVAVR
TH_1241|M.thermoresistible__bu SLSAVADSKQTLLCTYLSAVLLIGLLLNSLFGWSWADPVAGLAIAAMAVR
MAB_0183c|M.abscessus_ATCC_199 SLNVEGAFQHILNDLYAFIATAVAGAVVWLTGFTRADAIAALVVAALMLK
MLBr_00283|M.leprae_Br4923 SLAIKGAYMEAVADTVGNIGVLIAGVVTLTTHWPYADVVVAVLVALWVLP
* . . . : ** : .: ::
MMAR_3313|M.marinum_M VGWEVSSEIGHRLLDGVDPGVVDTAEAVAAAIPGVVHAH-ARARWTGRTL
MUL_1315|M.ulcerans_Agy99 VGWEVSSEIGHRLLDGVDPGVVDTAEAVAAAIPGVVHAH-ARARWTGRTL
MAV_3555|M.avium_104 VGWEVTADIAHRLLDGVDPDIVTTAEAVAVSVPGVTHAH-ARARWTGRTL
Mb2050c|M.bovis_AF2122/97 VLRTAARDVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRL
Rv2025c|M.tuberculosis_H37Rv VLRTAARDVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRL
Mflv_1902|M.gilvum_PYR-GCK ILRTAARDIFRRLMDGVDPGFVASAESALAAEPGVLAVRSVRMRWVGHRL
Mvan_3225|M.vanbaalenii_PYR-1 VLRTAVRDVFRRLMDGVDPAFVDSAEAALAAEPGVSQVRTVRMRWIGHRL
MSMEG_5604|M.smegmatis_MC2_155 EG---------------------------------------LEAWKGDTC
TH_1241|M.thermoresistible__bu EG---------------------------------------IEAWRGDTC
MAB_0183c|M.abscessus_ATCC_199 AGWGLVRESGRIFLEAAPVGLDPGTIGTQLAAVHAVAEVHDLHIWQITSG
MLBr_00283|M.leprae_Br4923 RAISLAR-----------------------------------AACGSFPN
MMAR_3313|M.marinum_M RVEVEGWVDPAMSVADADDIGRRVADQLGARLPQMRSFSWAARGVPLG--
MUL_1315|M.ulcerans_Agy99 RVEVEGWADPAMSVADADDIGRRVADQLGARLPQMRSFSWAARGVPLG--
MAV_3555|M.avium_104 RVEVEGFLDAATSLSDSDRIGRSVAAALAPRLPQMQSFTWTARAA-----
Mb2050c|M.bovis_AF2122/97 HADAELDVDPALDLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSS
Rv2025c|M.tuberculosis_H37Rv HADAELDVDPALDLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSS
Mflv_1902|M.gilvum_PYR-GCK HADAELDIDPAVSLADAHRIAHEAEHTLTHAVPKLASALVHAYPDS----
Mvan_3225|M.vanbaalenii_PYR-1 HAEAELDIDPAVTLADAHRIAHRAEHTLTHAVPKLSTALVHAYPGSSDRG
MSMEG_5604|M.smegmatis_MC2_155 CSAG----------------------------------------------
TH_1241|M.thermoresistible__bu CAVPVGTSRTATESGCGCGDDRE---------------------------
MAB_0183c|M.abscessus_ATCC_199 QPALSAHILVAPN-ADCHGIRREIEELLHTQYDIDHTTLQVDHEGTEAST
MLBr_00283|M.leprae_Br4923 CRRPTIDVEALRSALGRRRRHRSARPARVNTFARRRYVPPRT--------
MMAR_3313|M.marinum_M ---------------------
MUL_1315|M.ulcerans_Agy99 ---------------------
MAV_3555|M.avium_104 ---------------------
Mb2050c|M.bovis_AF2122/97 IPDRGRTVE------------
Rv2025c|M.tuberculosis_H37Rv IPDRGRTVE------------
Mflv_1902|M.gilvum_PYR-GCK ---GGSSH-------------
Mvan_3225|M.vanbaalenii_PYR-1 A-RGGSSVG------------
MSMEG_5604|M.smegmatis_MC2_155 ---------------------
TH_1241|M.thermoresistible__bu ---------------------
MAB_0183c|M.abscessus_ATCC_199 HCFDPHGEPYRADGSALPGKG
MLBr_00283|M.leprae_Br4923 ---------------------