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VIVGFPGDPVDTVILPGGAGVDAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLGRTPSDDALG LCRTFRPRISGRSGRCRPDLHAQFAEGVDRGWSHRRHRPRAGTGRRRPRHRDCPDGCPLARPVSAPTRWA DPVRGSGVDATRQTDLDPPGAGGHRGRAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTE AARRQLEETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1931c | - | - | 100% (259) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv3833 | - | 2e-05 | 30.12% (83) | AraC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0052 | - | 9e-05 | 38.00% (50) | hypothetical protein Rv0052 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1966c | - | 1e-153 | 100.00% (259) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5267 | - | 1e-53 | 46.67% (270) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0942 | - | 3e-48 | 43.64% (275) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 1e-59 | 52.71% (277) | transcriptional regulatory protein |
| M. avium 104 | MAV_4981 | - | 1e-20 | 29.74% (269) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_1106 | - | 1e-52 | 46.52% (273) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3120 | - | 2e-20 | 31.18% (263) | PUTATIVE transcriptional regulator, AraC family with |
| M. ulcerans Agy99 | MUL_2902 | - | 4e-61 | 53.43% (277) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0972 | - | 3e-53 | 44.69% (273) | AraC family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1931c|M.tuberculosis_H37Rv -------------------MVIVGFPG-----------------------
Mb1966c|M.bovis_AF2122/97 -------------------MVIVGFPG-----------------------
Mflv_5267|M.gilvum_PYR-GCK ---------------MTRTVLIVGFAGVQALDIVGPFDVFTGASLAVTAR
Mvan_0972|M.vanbaalenii_PYR-1 MHGLDAIAALANTEPMVRTVVIVGFAGVQALDVVGPFDVFTGASLSVGAR
MAB_0942|M.abscessus_ATCC_1997 ---------------MRRSVVILGFPGVQALDLVGPYEVFATASRHMTGT
MSMEG_1106|M.smegmatis_MC2_155 ------MSRVFDTEVVTRSVVILGYSGVQALDLVGPFDVFTGAALWLAGQ
MMAR_2855|M.marinum_M ---------------MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEG-
MUL_2902|M.ulcerans_Agy99 ---------------MARKVVTVGFPGVQPLDVVGPFEVFAGASLLSEG-
MAV_4981|M.avium_104 ---------MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEANRFGAD-
TH_3120|M.thermoresistible__bu -------------------VAALVLDGLAIFEFGVICEVFGVDRTDDGVP
: : .
Rv1931c|M.tuberculosis_H37Rv ---------------------------------DP---VDTVILPGGAGV
Mb1966c|M.bovis_AF2122/97 ---------------------------------DP---VDTVILPGGAGV
Mflv_5267|M.gilvum_PYR-GCK G--GDGYAVTVVSVGGDPVSTGTGLTLTAVPLPDPGHPIDTLVLPGGFGA
Mvan_0972|M.vanbaalenii_PYR-1 GL-GDGYDVRVVAVDGAPVSTGTGLTLAADPLPGPDEAVDTVVLPGGWGA
MAB_0942|M.abscessus_ATCC_1997 T---PGYDVKLVSADGAPVSTGSGMELVTQPLPDPEPGCDTLLLPGGIGV
MSMEG_1106|M.smegmatis_MC2_155 GREQQAYTVTLASADGAPVTTLTGLEFVAAPPPDPCGDIDTVVIPGGIGA
MMAR_2855|M.marinum_M -----GYDVALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGV
MUL_2902|M.ulcerans_Agy99 -----GYDVALASIDERPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGV
MAV_4981|M.avium_104 ------YLLKIASVDGRDVTTSIGTRLGVTDAVSSIESADTVLVAGSDNL
TH_3120|M.thermoresistible__bu P----VDFTVCGPRAGQPVRTSFGATLTPDSGLDGLAGADLVAIP---AI
. * : :.
Rv1931c|M.tuberculosis_H37Rv DAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLGRTPSDDALGL
Mb1966c|M.bovis_AF2122/97 DAARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEAGLLGRTPSDDALGL
Mflv_5267|M.gilvum_PYR-GCK DAARRDDVLIDWITAIAPHARRVVSVCSGAVLAAQAGLLDGCVATTHWAY
Mvan_0972|M.vanbaalenii_PYR-1 DTARRDQVLIDWITAAAARARRVVSVCNGAVLAAQAGLLDGCVATTHWAY
MAB_0942|M.abscessus_ATCC_1997 SAVQRDAALMSWVRAAARGARRVVSVCNGAFLAAEAGLLDGCRATTHWAI
MSMEG_1106|M.smegmatis_MC2_155 DEARRNREVVNWIKTAADHARRVVTVCTGAFLAAEAGLLDGCPATTHWAS
MMAR_2855|M.marinum_M DAARDNVALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAF
MUL_2902|M.ulcerans_Agy99 DAARDNVALMDWVKAAAGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAF
MAV_4981|M.avium_104 PRRPIDPELVEAVKSVADRTRRLASICTGSFILGQAGLLDGRRATTHWHD
TH_3120|M.thermoresistible__bu RQDDYLPEALDAVRAAADAGAIILTVCSGAFLAGAAGLLDGRPCTTHWGL
:. : : : : ::*.*:.: . ****. .
Rv1931c|M.tuberculosis_H37Rv CRTFRPRISGRSGR-----CRPDLHAQFAEGVDRGWSHRRHRPRAGTGRR
Mb1966c|M.bovis_AF2122/97 CRTFRPRISGRSGR-----CRPDLHAQFAEGVDRGWSHRRHRPRAGTGRR
Mflv_5267|M.gilvum_PYR-GCK APHMAVEFPSVTVDPDPIFVRSSEKVWTAAGVTAGIDLALSLVEDDHGTE
Mvan_0972|M.vanbaalenii_PYR-1 APQLAAEFPSVTVDPDPIFVRSSEKVWTAAGVTAGIDLALALVEDDHGTE
MAB_0942|M.abscessus_ATCC_1997 AGQLASEFPSVTVDPDPIFIRSSDKTWTAAGVTAGIDLALALVEEDHGAE
MSMEG_1106|M.smegmatis_MC2_155 ARRLADEFPSVTVDPEPIFMRSSERVWTAAGVTAGIDLALSLVEDDHGTD
MMAR_2855|M.marinum_M ADRLAREFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTE
MUL_2902|M.ulcerans_Agy99 ADRLAREFPAVDVDPDPIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTE
MAV_4981|M.avium_104 VRLFARAFPEITVEPDALFVCDG-DVFTSAGISSGIDLALALVEMDYGTE
TH_3120|M.thermoresistible__bu TEELARRYPTARVDRNVLYVDDG-DLITSAGTAAGIDACLHLVRRELGSE
: . . : * * . . *
Rv1931c|M.tuberculosis_H37Rv RPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRG
Mb1966c|M.bovis_AF2122/97 RPRHRDCPDGCPLARPVSAPTRWADPVRGSGVDATRQTDLDPPGAGGHRG
Mflv_5267|M.gilvum_PYR-GCK LAQTVARHLVMYLRRPGGQ-TQFAAPVWMPRARRSPIRDVQEVIES----
Mvan_0972|M.vanbaalenii_PYR-1 TAQIVARHLVMYLRRPGGQ-TQFAAPVWMPRARRTPIRDVQEAVEA----
MAB_0942|M.abscessus_ATCC_1997 VAQAVARWLVLYLRRPGGQ-SQFAAPVWMPRAKRMPIRDVQEAIEA----
MSMEG_1106|M.smegmatis_MC2_155 VAQNVARWLVLYLRRPGGQ-TQFAAPVWMPRAKRAPIRAVQEAIEA----
MMAR_2855|M.marinum_M IAQTVARWLVLYLRRPGGQ-TQFAAPVWMPRAKRPSIRDVQEAIEA----
MUL_2902|M.ulcerans_Agy99 IAQTVARWLVLYLRRPCGQ-TQFAAPVWMPRAKRPSIRDVQEAIEA----
MAV_4981|M.avium_104 LVRAVARWLVVYLKRAGGQ-SQFSALVEAEPPPRSPLRKVTAAISA----
TH_3120|M.thermoresistible__bu VTNTIARHMVVPPQRDGGQ-RQFIDQPIPVRHSEGFAPHLDWILSN----
. * . :: :
Rv1931c|M.tuberculosis_H37Rv RAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQL
Mb1966c|M.bovis_AF2122/97 RAGGAHRIGELAQRAAMSPRHFTRVFSDEVGEAPGRYVERIRTEAARRQL
Mflv_5267|M.gilvum_PYR-GCK EPGAVHSISELARRAAMSTRHFTRAFTDEVGEAPGAYVERVRTEAARRQL
Mvan_0972|M.vanbaalenii_PYR-1 EPGGAHSIAELARLAAMSPRHFTRVFTEEVGEAPGAYVERVRTEAARRQL
MAB_0942|M.abscessus_ATCC_1997 EPSGSHRVPELARLAAMSPRHFTRVFTAEVGEAPSAYVERIRSEAARRQL
MSMEG_1106|M.smegmatis_MC2_155 DPGGAHSISDLAQRAAMSPRHFTRVFTEEVGQSPGVYVERIRIDAARRQL
MMAR_2855|M.marinum_M QPGGPHSIEELAHRAAMSPRHFTRVFTGEVGEAPRQYVERVRTEAARRQL
MUL_2902|M.ulcerans_Agy99 QPGGPHSIEELAHRAAMSPRHFTRVFTGEVGEAPGRYVERVRTEAARRQL
MAV_4981|M.avium_104 DPAADHSVKSLSARASLSTRQLTRLFQSELGTTPARYVEMVRIDAARAAL
TH_3120|M.thermoresistible__bu -LDKTHTVASLARRANMSPRTFARRFVEETGRTPMQWVTDQRVLYARRLL
* : .*: * :*.* ::* * * * :* :* * ** *
Rv1931c|M.tuberculosis_H37Rv EETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA--------
Mb1966c|M.bovis_AF2122/97 EETHDTVVAIAARCGFGTAETMRRSFIRRVGISPDQYRKAFA--------
Mflv_5267|M.gilvum_PYR-GCK EETDDTVTVIAARCGFGSAETLRRSFVRRLGVSPDQYRKTFA--------
Mvan_0972|M.vanbaalenii_PYR-1 EETDDTVTVIAARCGFGSAETLRRNFVRRLGVSPDQYRRTFA--------
MAB_0942|M.abscessus_ATCC_1997 EETDDTMVVIAGRCGFGSAESLRRNFVRRMGVSPDQYRKTFQRTDRSSV-
MSMEG_1106|M.smegmatis_MC2_155 EESDDTVTAIAARCGFGTAETMRRNFIRRLGVSPDQYRKTSALTGR----
MMAR_2855|M.marinum_M EETEDTVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA--------
MUL_2902|M.ulcerans_Agy99 EETEDTVVAIAARCGFGTAETMRRNFIRRVGISPDQYRKAFA--------
MAV_4981|M.avium_104 DAG-RSVAESARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRTAARG---
TH_3120|M.thermoresistible__bu EETDLDIHRIAARCGFGSTTLLRHHFRRVIGVTPSDYRRRFACGSTTSGS
: : * .***:: :*: * . :*::*. **
Rv1931c|M.tuberculosis_H37Rv ---------
Mb1966c|M.bovis_AF2122/97 ---------
Mflv_5267|M.gilvum_PYR-GCK ---------
Mvan_0972|M.vanbaalenii_PYR-1 ---------
MAB_0942|M.abscessus_ATCC_1997 ---------
MSMEG_1106|M.smegmatis_MC2_155 ---------
MMAR_2855|M.marinum_M ---------
MUL_2902|M.ulcerans_Agy99 ---------
MAV_4981|M.avium_104 ---------
TH_3120|M.thermoresistible__bu TESGAEVTD