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VTASPVRRQRLCYRRATMARKRRGWGGDPPATDSEAAQRIVVAAVDLIARTGAAITIADVAESLEVTRQT VYRYFSTADELMRAAAIASVDGFLDQLAAHVRGIHDPADAMTEGVMFTLDAVAAIPHLAILLSAPSEAAR PSEVTSDLAQDFGMRMITRFDVDWQRYGYDDAALRDLVEFTLRTMLSFFVAPNVRPPEELRRFLTRWLGS AILAQSVKA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3496 | - | - | 100% (220) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0372 | - | 2e-44 | 45.92% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5152 | - | 5e-42 | 45.64% (195) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 6e-05 | 25.33% (150) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3011 | - | 9e-88 | 82.59% (201) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 6e-05 | 25.33% (150) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4765 | - | 1e-67 | 63.45% (197) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 2e-62 | 61.11% (198) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_2960 | - | 5e-46 | 46.15% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2106 | - | 3e-71 | 68.53% (197) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_1262 | - | 6e-44 | 46.15% (195) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 6e-52 | 60.23% (171) | hypothetical protein MUL_4888 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3496|M.vanbaalenii_PYR-1 MVTASPVRRQRLCYRRATMARKRRGWGGDPPATDSEAAQRIVVAAVD---
Mflv_3011|M.gilvum_PYR-GCK ------------------MARKRRGWGGNPPETDEEATRRIVAAAVD---
MMAR_0226|M.marinum_M ------------------MAR-RRGWNGAPPASDEEASRRIVDTAVR---
MUL_4888|M.ulcerans_Agy99 ------------------MVS-RPKRRGVSRIG------RGVRRHRR---
MAB_4765|M.abscessus_ATCC_1997 ------------------MAR-RRGWDGQPPSSDEEAAERIVAAAVK---
MSMEG_2106|M.smegmatis_MC2_155 ------------------MAR-RRGWDGRPPANDEEASARIVEAAVA---
MAV_2960|M.avium_104 ------------------MRS--HGWAGNTPASDAEAIERILDAADR---
TH_1262|M.thermoresistible__bu ------------------MRT--HGWGGSAPASDEEAIARILEAAKR---
Mb3277c|M.bovis_AF2122/97 ------------------MSTPSATVAPVKRIPYAEASRALLRDSVLDAM
Rv3249c|M.tuberculosis_H37Rv ------------------MSTPSATVAPVKRIPYAEASRALLRDSVLDAM
* :
Mvan_3496|M.vanbaalenii_PYR-1 ---LIARTGAAITIADVAESLEVTRQTVYRYFSTADELMRAAAIASVDGF
Mflv_3011|M.gilvum_PYR-GCK ---LIAETGSAITIADVAESLGVIRQTVYRYFPTAQDLMREAAIASVDGF
MMAR_0226|M.marinum_M ---LIAETGSDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGF
MUL_4888|M.ulcerans_Agy99 ---GIAETGSDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGF
MAB_4765|M.abscessus_ATCC_1997 ---LIGETGSAVSLADVAAELGVIRQTVYRYFPTADALMHAASLASVDGF
MSMEG_2106|M.smegmatis_MC2_155 ---LISETGSDVSIADVAASLGVIRQTVYRYFPTADALMRAAAIASVDGF
MAV_2960|M.avium_104 ---IIAERGSALRIADVARALGVTRQTVYRYFPGTQALLVASAMRSADGF
TH_1262|M.thermoresistible__bu ---TIEERGAEFSIADVARAVGVTRQTVYRYFPSTDALLVAAAMHAAGDF
Mb3277c|M.bovis_AF2122/97 RDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRL
Rv3249c|M.tuberculosis_H37Rv RDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRL
: . : . :::** : ***:*. : : * :: .. :
Mvan_3496|M.vanbaalenii_PYR-1 LDQLAAHVRG-IHDPADAMTEGVMFTLDAVAAIPHLAILLSAPSEAARPS
Mflv_3011|M.gilvum_PYR-GCK LDQLEARVRG-ITDPADAMTEGFLFTLDAVVAIPHLGILLSSPSSAATPG
MMAR_0226|M.marinum_M LDRLTEAVRG-MRDPAEAMAEAVMFTLRDVVRTPHLGILIAQPYAHTHPE
MUL_4888|M.ulcerans_Agy99 LDRLTEAVRG-MRDPAEAMAEAVMFTLRDVVRTPHLGILIAQPYAHTHPE
MAB_4765|M.abscessus_ATCC_1997 LDRLTHVVRG-ITDPAEALTEGVLYTLEEVTRTPHLGIMMSEPYAHSHTS
MSMEG_2106|M.smegmatis_MC2_155 LDRLTAHVRG-ITDPAEAMTDGVLYTLEEVSRTPHLGIVLSEPYLHANSG
MAV_2960|M.avium_104 LDRMAAHLDG-VTDPVVAITEGMAFAVEELASDHQVEFVLNQRHRGGQKV
TH_1262|M.thermoresistible__bu LDRLAVHLQG-ITDPVEAVAEAIATTLEWLPEDTHIGLLVAPGRPTAHTE
Mb3277c|M.bovis_AF2122/97 VDNVHASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQ
Rv3249c|M.tuberculosis_H37Rv VDNVHASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQ
:*.: : . : : *. :.. . : ::
Mvan_3496|M.vanbaalenii_PYR-1 EVTSDLAQDFGMRMITRFDVDWQRYGY-DDAALRDLVEFTLRTMLSFFVA
Mflv_3011|M.gilvum_PYR-GCK EVASALAQDVGMRMITRFDVDWQRYGY-DDAALRDLVEFTLRTMLSFFVA
MMAR_0226|M.marinum_M NLTSEEAQVFGVRMLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVA
MUL_4888|M.ulcerans_Agy99 NLTSEEAQVFGVRMLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVA
MAB_4765|M.abscessus_ATCC_1997 DMTSDEAQAFGLRMLDRFDVDWVQYGY-DDAAKRELVEFALRIMLSFFVS
MSMEG_2106|M.smegmatis_MC2_155 SLASDEAQDFGMRMLKRFDVDWAAYGY-DEAAQRELVEFTLRIMLSFFVA
MAV_2960|M.avium_104 SIISDTALAFGRSMLHRYDIDWESYGF-DEAGLEELNEFSLRVLHSFLTD
TH_1262|M.thermoresistible__bu SVTSDVAIDFANRMLRRFDVDWAAVGY-SDADLDELAEHLLRVIQSFVID
Mb3277c|M.bovis_AF2122/97 LITTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSM
Rv3249c|M.tuberculosis_H37Rv LITTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSM
: : * . : * . :* *:.
Mvan_3496|M.vanbaalenii_PYR-1 PN--VRPPE-ELRRFLTRWLGSAILAQSVKA-------------------
Mflv_3011|M.gilvum_PYR-GCK PNDPSRSRE-ELRRFLRRWLGSAILAQASPSRISPSISSTG---------
MMAR_0226|M.marinum_M PNVPSRSDD-ELKSFIKRWVGGAILAQKR---------------------
MUL_4888|M.ulcerans_Agy99 PNVPSRSDD-ELKSFIRRWVGGAIVAQKR---------------------
MAB_4765|M.abscessus_ATCC_1997 PNEATRSRD-ELRGFLKRWLGGAVLAQGR---------------------
MSMEG_2106|M.smegmatis_MC2_155 PNEATRSRE-ELRRFIRRWLGGALLAQPRATAAPSSST------------
MAV_2960|M.avium_104 PGRPPRTGA-DLRRYLTRWIGPAIAYPQLLRAMDALGAAEPQQRPRRRAS
TH_1262|M.thermoresistible__bu PGRPPRDGQ-SLRAYLRRWVGAAVTGAR----------------------
Mb3277c|M.bovis_AF2122/97 PPEADHDVAADLARLITPFAERHGVINVP---------------------
Rv3249c|M.tuberculosis_H37Rv PPEADHDVAADLARLITPFAERHGVINVP---------------------
* : .* : :
Mvan_3496|M.vanbaalenii_PYR-1 ---
Mflv_3011|M.gilvum_PYR-GCK ---
MMAR_0226|M.marinum_M ---
MUL_4888|M.ulcerans_Agy99 ---
MAB_4765|M.abscessus_ATCC_1997 ---
MSMEG_2106|M.smegmatis_MC2_155 ---
MAV_2960|M.avium_104 KAS
TH_1262|M.thermoresistible__bu ---
Mb3277c|M.bovis_AF2122/97 ---
Rv3249c|M.tuberculosis_H37Rv ---