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MARKRRGWGGNPPETDEEATRRIVAAAVDLIAETGSAITIADVAESLGVIRQTVYRYFPTAQDLMREAAI ASVDGFLDQLEARVRGITDPADAMTEGFLFTLDAVVAIPHLGILLSSPSSAATPGEVASALAQDVGMRMI TRFDVDWQRYGYDDAALRDLVEFTLRTMLSFFVAPNDPSRSREELRRFLRRWLGSAILAQASPSRISPSI SSTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3011 | - | - | 100% (214) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4281 | - | 6e-43 | 45.13% (195) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0364 | - | 8e-40 | 40.09% (212) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 2e-05 | 33.33% (105) | transcriptional regulatory protein TetR-family |
| M. tuberculosis H37Rv | Rv3830c | - | 2e-05 | 33.33% (105) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4765 | - | 1e-71 | 65.48% (197) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 5e-66 | 63.13% (198) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_2960 | - | 4e-45 | 44.85% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2106 | - | 6e-77 | 70.73% (205) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_1262 | - | 3e-43 | 44.33% (194) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 3e-55 | 62.57% (171) | hypothetical protein MUL_4888 |
| M. vanbaalenii PYR-1 | Mvan_3496 | - | 9e-88 | 82.59% (201) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3011|M.gilvum_PYR-GCK ------------------MARKRRGWGGNPPETDEEATRRIVAAAVDLIA
Mvan_3496|M.vanbaalenii_PYR-1 MVTASPVRRQRLCYRRATMARKRRGWGGDPPATDSEAAQRIVVAAVDLIA
MMAR_0226|M.marinum_M ------------------MAR-RRGWNGAPPASDEEASRRIVDTAVRLIA
MUL_4888|M.ulcerans_Agy99 ------------------MVS-RPKRRGVSRIG------RGVRRHRRGIA
MAB_4765|M.abscessus_ATCC_1997 ------------------MAR-RRGWDGQPPSSDEEAAERIVAAAVKLIG
MSMEG_2106|M.smegmatis_MC2_155 ------------------MAR-RRGWDGRPPANDEEASARIVEAAVALIS
MAV_2960|M.avium_104 ------------------MRS--HGWAGNTPASDAEAIERILDAADRIIA
TH_1262|M.thermoresistible__bu ------------------MRT--HGWGGSAPASDEEAIARILEAAKRTIE
Mb3860c|M.bovis_AF2122/97 ------------------MVR-----PPQTARSERTREALRQAALVRFLA
Rv3830c|M.tuberculosis_H37Rv ------------------MVR-----PPQTARSERTREALRQAALVRFLA
* . :
Mflv_3011|M.gilvum_PYR-GCK ETGSAITIADVAESLGVIRQTVYRYFPTAQDLMREAAIASVDGFLDQLEA
Mvan_3496|M.vanbaalenii_PYR-1 RTGAAITIADVAESLEVTRQTVYRYFSTADELMRAAAIASVDGFLDQLAA
MMAR_0226|M.marinum_M ETGSDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTE
MUL_4888|M.ulcerans_Agy99 ETGSDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTE
MAB_4765|M.abscessus_ATCC_1997 ETGSAVSLADVAAELGVIRQTVYRYFPTADALMHAASLASVDGFLDRLTH
MSMEG_2106|M.smegmatis_MC2_155 ETGSDVSIADVAASLGVIRQTVYRYFPTADALMRAAAIASVDGFLDRLTA
MAV_2960|M.avium_104 ERGSALRIADVARALGVTRQTVYRYFPGTQALLVASAMRSADGFLDRMAA
TH_1262|M.thermoresistible__bu ERGAEFSIADVARAVGVTRQTVYRYFPSTDALLVAAAMHAAGDFLDRLAV
Mb3860c|M.bovis_AF2122/97 QGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDA
Rv3830c|M.tuberculosis_H37Rv QGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDA
. ::* * :*.**:: . *: . * :
Mflv_3011|M.gilvum_PYR-GCK RVR--GITDPADAMTEGFLFTLDAVVAIPHLG-ILLSSPSSAATPGEVAS
Mvan_3496|M.vanbaalenii_PYR-1 HVR--GIHDPADAMTEGVMFTLDAVAAIPHLA-ILLSAPSEAARPSEVTS
MMAR_0226|M.marinum_M AVR--GMRDPAEAMAEAVMFTLRDVVRTPHLG-ILIAQPYAHTHPENLTS
MUL_4888|M.ulcerans_Agy99 AVR--GMRDPAEAMAEAVMFTLRDVVRTPHLG-ILIAQPYAHTHPENLTS
MAB_4765|M.abscessus_ATCC_1997 VVR--GITDPAEALTEGVLYTLEEVTRTPHLG-IMMSEPYAHSHTSDMTS
MSMEG_2106|M.smegmatis_MC2_155 HVR--GITDPAEAMTDGVLYTLEEVSRTPHLG-IVLSEPYLHANSGSLAS
MAV_2960|M.avium_104 HLD--GVTDPVVAITEGMAFAVEELASDHQVE-FVLNQRHRGGQKVSIIS
TH_1262|M.thermoresistible__bu HLQ--GITDPVEAVAEAIATTLEWLPEDTHIG-LLVAPGRPTAHTESVTS
Mb3860c|M.bovis_AF2122/97 RPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEA
Rv3830c|M.tuberculosis_H37Rv RPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEA
.: *.. * .. : : : : .: :
Mflv_3011|M.gilvum_PYR-GCK ALAQDVGMRMITR-FDVDWQRYGY--DDAALRDLVEFTLRTMLSFFVAPN
Mvan_3496|M.vanbaalenii_PYR-1 DLAQDFGMRMITR-FDVDWQRYGY--DDAALRDLVEFTLRTMLSFFVAPN
MMAR_0226|M.marinum_M EEAQVFGVRMLER-FDVDWAEYGFA-DESARHDLVEFLLRVLLSFFVAPN
MUL_4888|M.ulcerans_Agy99 EEAQVFGVRMLER-FDVDWAEYGFA-DESARHDLVEFLLRVLLSFFVAPN
MAB_4765|M.abscessus_ATCC_1997 DEAQAFGLRMLDR-FDVDWVQYGY--DDAAKRELVEFALRIMLSFFVSPN
MSMEG_2106|M.smegmatis_MC2_155 DEAQDFGMRMLKR-FDVDWAAYGY--DEAAQRELVEFTLRIMLSFFVAPN
MAV_2960|M.avium_104 DTALAFGRSMLHR-YDIDWESYGF--DEAGLEELNEFSLRVLHSFLTDPG
TH_1262|M.thermoresistible__bu DVAIDFANRMLRR-FDVDWAAVGY--SDADLDELAEHLLRVIQSFVIDPG
Mb3860c|M.bovis_AF2122/97 DFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSD
Rv3830c|M.tuberculosis_H37Rv DFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSD
* . : * *: . : : : ::. ..
Mflv_3011|M.gilvum_PYR-GCK DPSRSREELRRFLRRWLGSAILAQASPSRISPSISSTG------------
Mvan_3496|M.vanbaalenii_PYR-1 --VRPPEELRRFLTRWLGSAILAQSVKA----------------------
MMAR_0226|M.marinum_M VPSRSDDELKSFIKRWVGGAILAQKR------------------------
MUL_4888|M.ulcerans_Agy99 VPSRSDDELKSFIRRWVGGAIVAQKR------------------------
MAB_4765|M.abscessus_ATCC_1997 EATRSRDELRGFLKRWLGGAVLAQGR------------------------
MSMEG_2106|M.smegmatis_MC2_155 EATRSREELRRFIRRWLGGALLAQPRATAAPSSST---------------
MAV_2960|M.avium_104 RPPRTGADLRRYLTRWIGPAIAYPQLLRAMDALGAAEPQQRPRRRASKAS
TH_1262|M.thermoresistible__bu RPPRDGQSLRAYLRRWVGAAVTGAR-------------------------
Mb3860c|M.bovis_AF2122/97 RSLGELARVCHVALESLRVGISDTWTTLTVSS------------------
Rv3830c|M.tuberculosis_H37Rv RSLGELARVCHVALESLRVGISDTWTTLTVSS------------------
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