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VAGPSLEWERITAQVMRCRLPFCDVTVGVVHAGGEALVVDTGTTLAEARAVVRDVAALTDCVVRHVVVTH NHFDHVLGHSAFGGAQTFCSAEVVATMADAGESLRADAIRHGADPCEVDDALAALRPPVGAVCDGVVELG DVVVTIAHPGRGHTAHDLIVVVEGGPRTVVFCGDLVEESGDPCIDAQSDLDAWPGTLRRVLAAGGESAVY VPGHGALVDASFLRRQADWLATAASGRGQVGC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3402 | - | - | 100% (243) | beta-lactamase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1948 | - | 1e-73 | 59.40% (234) | hypothetical protein Mb1948 |
| M. gilvum PYR-GCK | Mflv_3131 | - | 6e-88 | 68.58% (226) | beta-lactamase domain-containing protein |
| M. tuberculosis H37Rv | Rv1913 | - | 1e-73 | 59.40% (234) | hypothetical protein Rv1913 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2020c | - | 3e-09 | 27.60% (221) | bifunctional HHDD isomerase/cyclase/dehydrase |
| M. marinum M | MMAR_2819 | - | 1e-69 | 55.36% (233) | hypothetical protein MMAR_2819 |
| M. avium 104 | MAV_2782 | - | 4e-72 | 57.45% (235) | metallo-beta-lactamase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2173 | - | 9e-68 | 56.25% (224) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2742 | - | 7e-07 | 31.65% (139) | hypothetical protein MUL_2742 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3402|M.vanbaalenii_PYR-1 MVAGPSLEWER-------ITAQVMRCRLPFCDVTVGVVHAGGEALVVDTG
Mflv_3131|M.gilvum_PYR-GCK ---MSELVWER-------LTRHVMRCRLPFCDVTVGVVHSDGAAVVIDCG
MMAR_2819|M.marinum_M ----MNYDWEQ-------LPGSVYRCRLPFCDVTVGLVIGRDDALLVDSG
MAV_2782|M.avium_104 ----MHLAWER-------LTGSVHRCRLPFCDVTVGLICGRSGTLLVDTG
Mb1948|M.bovis_AF2122/97 ----MHFDWER-------LTDSVHRCRLPFCDVTVGLVRGRTGILLVDTG
Rv1913|M.tuberculosis_H37Rv ----MHFDWER-------LTDSVHRCRLPFCDVTVGLVRGRTGILLVDTG
TH_2173|M.thermoresistible__bu ----VNFTWER-------LADKVFRTRLPFLDVTVGVVCGSTGTLLVDTG
MAB_2020c|M.abscessus_ATCC_199 --MAQDFAFQKGLVPLGGGAHVFLSGDEGFGLANAGLVVSDDESLVVDTL
MUL_2742|M.ulcerans_Agy99 ----MKVHHHNCG--TMNSPGAALLCHVLLVEAGNGLVLVDTGFGVQDCL
.. . : . *:: : *
Mvan_3402|M.vanbaalenii_PYR-1 --------------TTLAEARAVVRDVA-ALTDCVVRHVVVTHNHFDHVL
Mflv_3131|M.gilvum_PYR-GCK --------------TTLTEARAVAADVS-ELTGCAVTHLVLTHHHFDHVL
MMAR_2819|M.marinum_M --------------STLREAAAIQADIR-QLADRRVAHIALTHKHFDHVL
MAV_2782|M.avium_104 --------------TTLTEAAAIDADVH-RLARRPVSHIALTHKHFDHVL
Mb1948|M.bovis_AF2122/97 --------------TTLGEATAIAADVK-QIAGCQVTHVVLTHKHFDHVL
Rv1913|M.tuberculosis_H37Rv --------------TTLGEATAIAADVK-QIAGCQVTHVVLTHKHFDHVL
TH_2173|M.thermoresistible__bu --------------TTLGEAAAIVADVG-ELAATPITHILLTHNDFDHIL
MAB_2020c|M.abscessus_ATCC_199 --------------YDVRHAREMLDEFGRHTATAPVRYVFNTHTDGDHFF
MUL_2742|M.ulcerans_Agy99 DQRRLGAFRHFLRPALLQNETAVHQIERLGYRPSDVRHIVLTHFDSDHIG
: . : : :: ** . **.
Mvan_3402|M.vanbaalenii_PYR-1 GHSAFGG-AQTFCSAEVVATMADAG--ESLRADAIRHGADPCEVDDALAA
Mflv_3131|M.gilvum_PYR-GCK GHPVFDG-AQTFCSPEVTAALHER---EWLRSDALRYGADPQEVDDALTA
MMAR_2819|M.marinum_M GSSAFVG-AEIYCAPEVAEYLSSAS--HQLREDALHHGADAGEIDTAIAA
MAV_2782|M.avium_104 GSSLFTG-AEVYCAPEVVEYLGAAT--DQIRDDALRHGADAAEVDAAIAA
Mb1948|M.bovis_AF2122/97 GSSVFDQ-AEVFCAPEVVEYLRSAT--DRLREDALSYGADTAEVDRAIAA
Rv1913|M.tuberculosis_H37Rv GSSVFDQ-AEVFCAPEVVEYLRSAT--DRLREDALSYGADTAEVDRAIAA
TH_2173|M.thermoresistible__bu GIGGHPG-AEVFSTDRVVATLLHES--AQLRDEALSYDADPQEIDAAIAA
MAB_2020c|M.abscessus_ATCC_199 GNQVFADDVEIITTEAARALMVQEH--ADLTAELLGGSSDPASNMHVLAP
MUL_2742|M.ulcerans_Agy99 GLADFPDAQVHVTSAEARGAIHAPSFRERVRYRSVQWAHGPKLVEHGHDG
* . : . : : : ..
Mvan_3402|M.vanbaalenii_PYR-1 LRPPVGA------------VCDGVVELGDVVVTIAHPGRGHTAHDLIVVV
Mflv_3131|M.gilvum_PYR-GCK AVPPAVA------------VPYGTVELAGVVVRISHPGRGHTGHDLIAVV
MMAR_2819|M.marinum_M LRPPRHP------------ILDADVHLGDRRVRITHLGRGHTSADLVVVA
MAV_2782|M.avium_104 LRPGQHG------------IRDARIDLGDRTVTITHLGAGHTASDLAVIV
Mb1948|M.bovis_AF2122/97 LKPPQHG------------IYDAAVDLGDRTVTITHPGSGHTTADLVVVA
Rv1913|M.tuberculosis_H37Rv LKPPQHG------------IYDAAVDLGDRTVTITHPGSGHTTADLVVVA
TH_2173|M.thermoresistible__bu RRIPDHA------------VRQAVVGLGDRTVSIVHPGRGHTDHDLIAVV
MAB_2020c|M.abscessus_ATCC_199 LAKPFHFNEVRVRPADTTFSGERALRVGKLDVELHELGPAHTVGDAVAFL
MUL_2742|M.ulcerans_Agy99 ESSPGFA------------AAKTLDAIADGVVLVPMPG--HTRGHAAVAV
:. * : * ** . .
Mvan_3402|M.vanbaalenii_PYR-1 E-----GGPRTVVFCGDLVEESGDPCIDAQSDLDAWPGTLRRVLAAGGES
Mflv_3131|M.gilvum_PYR-GCK T-----DGQDTVVFCGDLVEESGEPCVDDQSDPAAWPATLQRVVDAGGES
MMAR_2819|M.marinum_M TPPAAQTG-PVVVFTGDLVEESADPAIDADSDVAAWPATLERLLAIGGPD
MAV_2782|M.avium_104 --PAARDGEPTVVFTGDLVEESGDPAIDADSDVTAWPATLDRLLALGGPG
Mb1948|M.bovis_AF2122/97 PATGHADG-PTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPD
Rv1913|M.tuberculosis_H37Rv PATGHADG-PTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPD
TH_2173|M.thermoresistible__bu R--GAERP---VVFCGDLVEESGEPSVEADSDPGSWPATLDRLLRIGGPD
MAB_2020c|M.abscessus_ATCC_199 P-------EHRVLFSGDLLTR-GIVKVVWSGSIPNWIVALERIRAFG--A
MUL_2742|M.ulcerans_Agy99 D-----AGDRWILHCGDAFYHVGTLDGQSK-----VPFVLRSQEELFSFD
::. ** . . . . .*
Mvan_3402|M.vanbaalenii_PYR-1 AVYVPGHG-----ALVDASFLRRQADWLATAASGRGQVGC----------
Mflv_3131|M.gilvum_PYR-GCK GIYVPGHG-----AVVEAAFVRRQAQWLA----GR---------------
MMAR_2819|M.marinum_M AIYVPGHG-----SVVDADFIRGQRDWLKQRAHPGLR-------------
MAV_2782|M.avium_104 ARYVPGHG-----RVVDAAFVRRQRDWLRARAATR---------------
Mb1948|M.bovis_AF2122/97 ASYVPGHG-----KVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR---
Rv1913|M.tuberculosis_H37Rv ASYVPGHG-----KVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR---
TH_2173|M.thermoresistible__bu AVYVPGHG-----ATVDAAFVQRQRQWLAERV------------------
MAB_2020c|M.abscessus_ATCC_199 KIVVPGHGPLLVDAEVDAAIDRGIAFWSDLHEQANRLYDQGVPAQDATAL
MUL_2742|M.ulcerans_Agy99 RRQLRDNQ-----ARLAELQRRQDPGLLIICAHDPSLYAVAKDLS-----
: .: : :
Mvan_3402|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3131|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2819|M.marinum_M --------------------------------------------------
MAV_2782|M.avium_104 --------------------------------------------------
Mb1948|M.bovis_AF2122/97 --------------------------------------------------
Rv1913|M.tuberculosis_H37Rv --------------------------------------------------
TH_2173|M.thermoresistible__bu --------------------------------------------------
MAB_2020c|M.abscessus_ATCC_199 IDIAKYPEAMVTLPIIVTAIYHERNPEIPFQSLTQALESISGQLAKAAAG
MUL_2742|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3402|M.vanbaalenii_PYR-1 --
Mflv_3131|M.gilvum_PYR-GCK --
MMAR_2819|M.marinum_M --
MAV_2782|M.avium_104 --
Mb1948|M.bovis_AF2122/97 --
Rv1913|M.tuberculosis_H37Rv --
TH_2173|M.thermoresistible__bu --
MAB_2020c|M.abscessus_ATCC_199 PK
MUL_2742|M.ulcerans_Agy99 --