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VHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHF DHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRT VTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDAS YVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1913 | - | - | 100% (250) | hypothetical protein Rv1913 |
| M. tuberculosis H37Rv | Rv0939 | - | 5e-13 | 28.63% (227) | bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1948 | - | 1e-146 | 100.00% (250) | hypothetical protein Mb1948 |
| M. gilvum PYR-GCK | Mflv_3131 | - | 6e-67 | 56.71% (231) | beta-lactamase domain-containing protein |
| M. leprae Br4923 | MLBr_00270 | - | 2e-05 | 31.58% (95) | hypothetical protein MLBr_00270 |
| M. abscessus ATCC 19977 | MAB_2020c | - | 2e-06 | 26.29% (213) | bifunctional HHDD isomerase/cyclase/dehydrase |
| M. marinum M | MMAR_2819 | - | 1e-92 | 69.79% (235) | hypothetical protein MMAR_2819 |
| M. avium 104 | MAV_2782 | - | 2e-98 | 73.31% (236) | metallo-beta-lactamase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2173 | - | 3e-73 | 59.40% (234) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3402 | - | 2e-73 | 59.40% (234) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3131|M.gilvum_PYR-GCK ---MSELVWER-------LTRHVMRCRLPFCDVTVGVVHSDGAAVVIDCG
Mvan_3402|M.vanbaalenii_PYR-1 MVAGPSLEWER-------ITAQVMRCRLPFCDVTVGVVHAGGEALVVDTG
Rv1913|M.tuberculosis_H37Rv ----MHFDWER-------LTDSVHRCRLPFCDVTVGLVRGRTGILLVDTG
Mb1948|M.bovis_AF2122/97 ----MHFDWER-------LTDSVHRCRLPFCDVTVGLVRGRTGILLVDTG
MAV_2782|M.avium_104 ----MHLAWER-------LTGSVHRCRLPFCDVTVGLICGRSGTLLVDTG
MMAR_2819|M.marinum_M ----MNYDWEQ-------LPGSVYRCRLPFCDVTVGLVIGRDDALLVDSG
TH_2173|M.thermoresistible__bu ----VNFTWER-------LADKVFRTRLPFLDVTVGVVCGSTGTLLVDTG
MAB_2020c|M.abscessus_ATCC_199 --MAQDFAFQKGLVPLGGGAHVFLSGDEGFGLANAGLVVSDDESLVVDTL
MLBr_00270|M.leprae_Br4923 ---MAAATLFQ-------VTDSVHFARG--DAVNWALVADDTGVMLIDTG
: . . .. .:: :::*
Mflv_3131|M.gilvum_PYR-GCK TTLTEARAVAADVS-ELTGCAVTHLVLTHHHFDHVLGHPVFDG-AQTFCS
Mvan_3402|M.vanbaalenii_PYR-1 TTLAEARAVVRDVA-ALTDCVVRHVVVTHNHFDHVLGHSAFGG-AQTFCS
Rv1913|M.tuberculosis_H37Rv TTLGEATAIAADVK-QIAGCQVTHVVLTHKHFDHVLGSSVFDQ-AEVFCA
Mb1948|M.bovis_AF2122/97 TTLGEATAIAADVK-QIAGCQVTHVVLTHKHFDHVLGSSVFDQ-AEVFCA
MAV_2782|M.avium_104 TTLTEAAAIDADVH-RLARRPVSHIALTHKHFDHVLGSSLFTG-AEVYCA
MMAR_2819|M.marinum_M STLREAAAIQADIR-QLADRRVAHIALTHKHFDHVLGSSAFVG-AEIYCA
TH_2173|M.thermoresistible__bu TTLGEAAAIVADVG-ELAATPITHILLTHNDFDHILGIGGHPG-AEVFST
MAB_2020c|M.abscessus_ATCC_199 YDVRHAREMLDEFGRHTATAPVRYVFNTHTDGDHFFGNQVFADDVEIITT
MLBr_00270|M.leprae_Br4923 YPGDRDDVVASLRQLGYEAGDVRAILLTHAHIDHMGSAIWFASKHRTPVY
. : : : ** . **. . . .
Mflv_3131|M.gilvum_PYR-GCK PEVTAALHER-EWLRSDALR-------------YGADPQEVDDALTAAVP
Mvan_3402|M.vanbaalenii_PYR-1 AEVVATMADAGESLRADAIR-------------HGADPCEVDDALAALRP
Rv1913|M.tuberculosis_H37Rv PEVVEYLRSATDRLREDALS-------------YGADTAEVDRAIAALKP
Mb1948|M.bovis_AF2122/97 PEVVEYLRSATDRLREDALS-------------YGADTAEVDRAIAALKP
MAV_2782|M.avium_104 PEVVEYLGAATDQIRDDALR-------------HGADAAEVDAAIAALRP
MMAR_2819|M.marinum_M PEVAEYLSSASHQLREDALH-------------HGADAGEIDTAIAALRP
TH_2173|M.thermoresistible__bu DRVVATLLHESAQLRDEALS-------------YDADPQEIDAAIAARRI
MAB_2020c|M.abscessus_ATCC_199 EAARALMVQEHADLTAELLG-------------GSSDPASNMHVLAPLAK
MLBr_00270|M.leprae_Br4923 CHADEVGHTKREYLEQVSLLNIAMRVWQPRWAIWSGHVLRSGGLIRGGIP
. : : ... :
Mflv_3131|M.gilvum_PYR-GCK PAVA------------VPYGTVELAGVVVRISHPGRGHTGHDLIAVVT--
Mvan_3402|M.vanbaalenii_PYR-1 PVGA------------VCDGVVELGDVVVTIAHPGRGHTAHDLIVVVE--
Rv1913|M.tuberculosis_H37Rv PQHG------------IYDAAVDLGDRTVTITHPGSGHTTADLVVVAPAT
Mb1948|M.bovis_AF2122/97 PQHG------------IYDAAVDLGDRTVTITHPGSGHTTADLVVVAPAT
MAV_2782|M.avium_104 GQHG------------IRDARIDLGDRTVTITHLGAGHTASDLAVIVPAA
MMAR_2819|M.marinum_M PRHP------------ILDADVHLGDRRVRITHLGRGHTSADLVVVATPP
TH_2173|M.thermoresistible__bu PDHA------------VRQAVVGLGDRTVSIVHPGRGHTDHDLIAVVR--
MAB_2020c|M.abscessus_ATCC_199 PFHFNEVRVRPADTTFSGERALRVGKLDVELHELGPAHTVGDAVAFLP--
MLBr_00270|M.leprae_Br4923 TAQP-----------LTAETAAGLPGHPMAIFTPG--HTGGHCSYVVDG-
: : : * ** . .
Mflv_3131|M.gilvum_PYR-GCK --DGQDTVVFCGDLVEESGEPCVDDQSDPAAWPATLQRVVDAGG-ESGIY
Mvan_3402|M.vanbaalenii_PYR-1 --GGPRTVVFCGDLVEESGDPCIDAQSDLDAWPGTLRRVLAAGG-ESAVY
Rv1913|M.tuberculosis_H37Rv GHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGG-PDASY
Mb1948|M.bovis_AF2122/97 GHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGG-PDASY
MAV_2782|M.avium_104 RDGE-PTVVFTGDLVEESGDPAIDADSDVTAWPATLDRLLALGG-PGARY
MMAR_2819|M.marinum_M AAQTGPVVVFTGDLVEESADPAIDADSDVAAWPATLERLLAIGG-PDAIY
TH_2173|M.thermoresistible__bu --GAERPVVFCGDLVEESGEPSVEADSDPGSWPATLDRLLRIGG-PDAVY
MAB_2020c|M.abscessus_ATCC_199 ----EHRVLFSGDLLTR-GIVKVVWSGSIPNWIVALERIRAFG---AKIV
MLBr_00270|M.leprae_Br4923 -VLISGDALITGHPLLRHRGPQLLTAVFSHSQKQCLRSLDALGLLETRIL
.:: *. : . : * : *
Mflv_3131|M.gilvum_PYR-GCK VPGHG-----AVVEAAFVRRQAQWLA----GR------------------
Mvan_3402|M.vanbaalenii_PYR-1 VPGHG-----ALVDASFLRRQADWLATAASGRGQVGC-------------
Rv1913|M.tuberculosis_H37Rv VPGHG-----KVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR------
Mb1948|M.bovis_AF2122/97 VPGHG-----KVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR------
MAV_2782|M.avium_104 VPGHG-----RVVDAAFVRRQRDWLRARAATR------------------
MMAR_2819|M.marinum_M VPGHG-----SVVDADFIRGQRDWLKQRAHPGLR----------------
TH_2173|M.thermoresistible__bu VPGHG-----ATVDAAFVQRQRQWLAERV---------------------
MAB_2020c|M.abscessus_ATCC_199 VPGHGPLLVDAEVDAAIDRGIAFWSDLHEQANRLYDQGVPAQDATALIDI
MLBr_00270|M.leprae_Br4923 APGHG-----ELWHGPIREATEAALKQAGALTR-----------------
.**** .. : .
Mflv_3131|M.gilvum_PYR-GCK -------------------------------------------------
Mvan_3402|M.vanbaalenii_PYR-1 -------------------------------------------------
Rv1913|M.tuberculosis_H37Rv -------------------------------------------------
Mb1948|M.bovis_AF2122/97 -------------------------------------------------
MAV_2782|M.avium_104 -------------------------------------------------
MMAR_2819|M.marinum_M -------------------------------------------------
TH_2173|M.thermoresistible__bu -------------------------------------------------
MAB_2020c|M.abscessus_ATCC_199 AKYPEAMVTLPIIVTAIYHERNPEIPFQSLTQALESISGQLAKAAAGPK
MLBr_00270|M.leprae_Br4923 -------------------------------------------------