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VNYDWEQLPGSVYRCRLPFCDVTVGLVIGRDDALLVDSGSTLREAAAIQADIRQLADRRVAHIALTHKHF DHVLGSSAFVGAEIYCAPEVAEYLSSASHQLREDALHHGADAGEIDTAIAALRPPRHPILDADVHLGDRR VRITHLGRGHTSADLVVVATPPAAQTGPVVVFTGDLVEESADPAIDADSDVAAWPATLERLLAIGGPDAI YVPGHGSVVDADFIRGQRDWLKQRAHPGLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2819 | - | - | 100% (240) | hypothetical protein MMAR_2819 |
| M. marinum M | MMAR_4572 | - | 7e-11 | 29.73% (222) | bifunctional enzyme: 2-hydroxyhepta-2,4-diene- 1,7-dioate |
| M. marinum M | MMAR_2442 | - | 6e-05 | 30.60% (183) | hypothetical protein MMAR_2442 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1948 | - | 8e-93 | 69.79% (235) | hypothetical protein Mb1948 |
| M. gilvum PYR-GCK | Mflv_3131 | - | 1e-59 | 50.87% (230) | beta-lactamase domain-containing protein |
| M. tuberculosis H37Rv | Rv1913 | - | 8e-93 | 69.79% (235) | hypothetical protein Rv1913 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2020c | - | 3e-10 | 28.89% (225) | bifunctional HHDD isomerase/cyclase/dehydrase |
| M. avium 104 | MAV_2782 | - | 1e-94 | 71.19% (236) | metallo-beta-lactamase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2173 | - | 6e-67 | 54.70% (234) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1621 | - | 1e-05 | 27.98% (243) | hypothetical protein MUL_1621 |
| M. vanbaalenii PYR-1 | Mvan_3402 | - | 1e-69 | 55.36% (233) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1948|M.bovis_AF2122/97 ----MHFDWER-------LTDSVHRCRLP---FCDVTVGLVRGRTGILLV
Rv1913|M.tuberculosis_H37Rv ----MHFDWER-------LTDSVHRCRLP---FCDVTVGLVRGRTGILLV
MAV_2782|M.avium_104 ----MHLAWER-------LTGSVHRCRLP---FCDVTVGLICGRSGTLLV
MMAR_2819|M.marinum_M ----MNYDWEQ-------LPGSVYRCRLP---FCDVTVGLVIGRDDALLV
Mflv_3131|M.gilvum_PYR-GCK ---MSELVWER-------LTRHVMRCRLP---FCDVTVGVVHSDGAAVVI
Mvan_3402|M.vanbaalenii_PYR-1 MVAGPSLEWER-------ITAQVMRCRLP---FCDVTVGVVHAGGEALVV
TH_2173|M.thermoresistible__bu ----VNFTWER-------LADKVFRTRLP---FLDVTVGVVCGSTGTLLV
MAB_2020c|M.abscessus_ATCC_199 --MAQDFAFQKGLVPLGGGAHVFLSGDEG---FGLANAGLVVSDDESLVV
MUL_1621|M.ulcerans_Agy99 -MTVVDDNYTG-----HVDPGTVARRTLPGATILKASVGPVDNNAYLVTC
: . . : ...* : :
Mb1948|M.bovis_AF2122/97 DT-GTTLGEATAIAADVK-QIAGCQVTHVVLTHKHFDHVLGSSVFDQ-AE
Rv1913|M.tuberculosis_H37Rv DT-GTTLGEATAIAADVK-QIAGCQVTHVVLTHKHFDHVLGSSVFDQ-AE
MAV_2782|M.avium_104 DT-GTTLTEAAAIDADVH-RLARRPVSHIALTHKHFDHVLGSSLFTG-AE
MMAR_2819|M.marinum_M DS-GSTLREAAAIQADIR-QLADRRVAHIALTHKHFDHVLGSSAFVG-AE
Mflv_3131|M.gilvum_PYR-GCK DC-GTTLTEARAVAADVS-ELTGCAVTHLVLTHHHFDHVLGHPVFDG-AQ
Mvan_3402|M.vanbaalenii_PYR-1 DT-GTTLAEARAVVRDVA-ALTDCVVRHVVVTHNHFDHVLGHSAFGG-AQ
TH_2173|M.thermoresistible__bu DT-GTTLGEAAAIVADVG-ELAATPITHILLTHNDFDHILGIGGHPG-AE
MAB_2020c|M.abscessus_ATCC_199 DT-LYDVRHAREMLDEFGRHTATAPVRYVFNTHTDGDHFFGNQVFADDVE
MUL_1621|M.ulcerans_Agy99 SATGQTLLIDAANDAEVLIDLIRRYAPKIALIVTSHQHFDHWQALQAVAE
. : :. : :*. .:
Mb1948|M.bovis_AF2122/97 VFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHG-----
Rv1913|M.tuberculosis_H37Rv VFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHG-----
MAV_2782|M.avium_104 VYCAPEVVEYLGAATDQIRDDALRHGADAAEVDAAIAALRPGQHG-----
MMAR_2819|M.marinum_M IYCAPEVAEYLSSASHQLREDALHHGADAGEIDTAIAALRPPRHP-----
Mflv_3131|M.gilvum_PYR-GCK TFCSPEVTAALHER-EWLRSDALRYGADPQEVDDALTAAVPPAVA-----
Mvan_3402|M.vanbaalenii_PYR-1 TFCSAEVVATMADAGESLRADAIRHGADPCEVDDALAALRPPVGA-----
TH_2173|M.thermoresistible__bu VFSTDRVVATLLHESAQLRDEALSYDADPQEIDAAIAARRIPDHA-----
MAB_2020c|M.abscessus_ATCC_199 IITTEAARALMVQEHADLTAELLGGSSDPASNMHVLAPLAKPFHFNEVRV
MUL_1621|M.ulcerans_Agy99 ATGAPTAAHEIDAEPLPVKPDRLLANGD----------------------
: . : : : : ..*
Mb1948|M.bovis_AF2122/97 -------IYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVV
Rv1913|M.tuberculosis_H37Rv -------IYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVV
MAV_2782|M.avium_104 -------IRDARIDLGDRTVTITHLGAGHTASDLAVIVPAARDGE-PTVV
MMAR_2819|M.marinum_M -------ILDADVHLGDRRVRITHLGRGHTSADLVVVATPPAAQTGPVVV
Mflv_3131|M.gilvum_PYR-GCK -------VPYGTVELAGVVVRISHPGRGHTGHDLIAVVTDG----QDTVV
Mvan_3402|M.vanbaalenii_PYR-1 -------VCDGVVELGDVVVTIAHPGRGHTAHDLIVVVEGG----PRTVV
TH_2173|M.thermoresistible__bu -------VRQAVVGLGDRTVSIVHPGRGHTDHDLIAVVRGA----ERPVV
MAB_2020c|M.abscessus_ATCC_199 RPADTTFSGERALRVGKLDVELHELGPAHTVGDAVAFLPEHR------VL
MUL_1621|M.ulcerans_Agy99 -----------RVQIGELSFDVIHLR-GHTPGSIALALDGAATG-GVTQL
: :. . : . .** . :
Mb1948|M.bovis_AF2122/97 FTGDLVEESADPDIDADSDLAAWPATLD-RVLAIGGPDASYVPGHG----
Rv1913|M.tuberculosis_H37Rv FTGDLVEESADPDIDADSDLAAWPATLD-RVLAIGGPDASYVPGHG----
MAV_2782|M.avium_104 FTGDLVEESGDPAIDADSDVTAWPATLD-RLLALGGPGARYVPGHG----
MMAR_2819|M.marinum_M FTGDLVEESADPAIDADSDVAAWPATLE-RLLAIGGPDAIYVPGHG----
Mflv_3131|M.gilvum_PYR-GCK FCGDLVEESGEPCVDDQSDPAAWPATLQ-RVVDAGGESGIYVPGHG----
Mvan_3402|M.vanbaalenii_PYR-1 FCGDLVEESGDPCIDAQSDLDAWPGTLR-RVLAAGGESAVYVPGHG----
TH_2173|M.thermoresistible__bu FCGDLVEESGEPSVEADSDPGSWPATLD-RLLRIGGPDAVYVPGHG----
MAB_2020c|M.abscessus_ATCC_199 FSGDLLTR-GIVKVVWSGSIPNWIVALE-RIRAFG--AKIVVPGHGPLLV
MUL_1621|M.ulcerans_Agy99 FTGDCLFPGGVGKTWQPGDFTQLVEDVSSRVFNVYPDSTVVYPGHG----
* ** : . .. : *: ****
Mb1948|M.bovis_AF2122/97 -KVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR---------------
Rv1913|M.tuberculosis_H37Rv -KVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR---------------
MAV_2782|M.avium_104 -RVVDAAFVRRQRDWLRARAATR---------------------------
MMAR_2819|M.marinum_M -SVVDADFIRGQRDWLKQRAHPGLR-------------------------
Mflv_3131|M.gilvum_PYR-GCK -AVVEAAFVRRQAQWLA----GR---------------------------
Mvan_3402|M.vanbaalenii_PYR-1 -ALVDASFLRRQADWLATAASGRGQVGC----------------------
TH_2173|M.thermoresistible__bu -ATVDAAFVQRQRQWLA----ERV--------------------------
MAB_2020c|M.abscessus_ATCC_199 DAEVDAAIDRGIAFWSDLHEQANRLYDQGVPAQDATALIDIAKYPEAMVT
MUL_1621|M.ulcerans_Agy99 -DDTALGFERPHLDEWRERGW-----------------------------
. : :
Mb1948|M.bovis_AF2122/97 ----------------------------------------
Rv1913|M.tuberculosis_H37Rv ----------------------------------------
MAV_2782|M.avium_104 ----------------------------------------
MMAR_2819|M.marinum_M ----------------------------------------
Mflv_3131|M.gilvum_PYR-GCK ----------------------------------------
Mvan_3402|M.vanbaalenii_PYR-1 ----------------------------------------
TH_2173|M.thermoresistible__bu ----------------------------------------
MAB_2020c|M.abscessus_ATCC_199 LPIIVTAIYHERNPEIPFQSLTQALESISGQLAKAAAGPK
MUL_1621|M.ulcerans_Agy99 ----------------------------------------