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GAEDPILTVVVDLLENEGYDAVQLREVARRSRTSLTTIYKRYSNRDELILAALEAWTDTHRYAAVAEQRR EPGETLHDALMRLFRVLFEPWERHPAMLAAYFRARTGPSGKRLLRRGLDVVVPAALDVLAGVDEEFIADM DTVIANVIYGLLGRFAAGEITITDILPAIDRTVYRLTAGYALEAAGDGVRRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3393 | - | - | 100% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0855 | - | 9e-07 | 37.50% (72) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0321 | - | 1e-06 | 27.66% (188) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 5e-06 | 30.61% (98) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_1903 | - | 6e-60 | 61.02% (177) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 5e-06 | 30.61% (98) | regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3372 | - | 4e-08 | 27.91% (172) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0929 | - | 1e-67 | 67.42% (178) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3548 | - | 3e-56 | 55.43% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5811 | - | 6e-65 | 62.70% (185) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2255 | - | 3e-08 | 28.75% (160) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_0681 | - | 3e-67 | 66.29% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0929|M.marinum_M --------MTARVGTQLASPETVTAPAVRRDDR--ILDIVVHLLQTEGYD
MUL_0681|M.ulcerans_Agy99 --------MTARVGTQLASPETVTAPAVRRDDR--ILDIVVHLLQTEGYD
Mvan_3393|M.vanbaalenii_PYR-1 ---------------------------MGAEDP--ILTVVVDLLENEGYD
Mflv_1903|M.gilvum_PYR-GCK ----------------------MDEGTAPHPDRDGLLDVVVDMLETDGYD
MSMEG_5811|M.smegmatis_MC2_155 ----------------------MGEDIEERDDR--LLDVVTEILETEGYE
MAV_3548|M.avium_104 ------------------MTAKGPDAPIVSGDP--ILGIVVDMLDTGGYE
Mb1581|M.bovis_AF2122/97 -----------MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYD
Rv1556|M.tuberculosis_H37Rv -----------MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYD
MAB_3372|M.abscessus_ATCC_1997 MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHVFADFGYA
TH_2255|M.thermoresistible__bu ------------------------MPERPDPARQAILDAAVVEFEQHGFR
:* . : *:
MMAR_0929|M.marinum_M AVQLREVARRARTSLATIYKRYANRDELILAALEFWMDEHHYAGL-AEQT
MUL_0681|M.ulcerans_Agy99 AVQLREVARRARTSLATIYKRYANRDELILAALEFWMDEHHYAGL-AEQT
Mvan_3393|M.vanbaalenii_PYR-1 AVQLREVARRSRTSLTTIYKRYSNRDELILAALEAWTDTHRYAAV-AEQR
Mflv_1903|M.gilvum_PYR-GCK AVQLRVVARRARSSLATIYKRYPTRDDLILAALEYWVARHRYAGI-AVPP
MSMEG_5811|M.smegmatis_MC2_155 AVQLREVARRARTSLATIYKRFATRDDLILAALEYWMQKNRYSGV-TPRR
MAV_3548|M.avium_104 AVQLREVARRARVSMATIYKRYRTRDELIVAALEGWMDANRYARLPSLID
Mb1581|M.bovis_AF2122/97 RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPN-----
Rv1556|M.tuberculosis_H37Rv RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPN-----
MAB_3372|M.abscessus_ATCC_1997 AGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRG-FALIHQHLA
TH_2255|M.thermoresistible__bu KVALEDVARRAGVSRTTIYRRFTNRDELVAAVVDRENAALFADIAAELKH
:* : * ::*: : .: :: .
MMAR_0929|M.marinum_M PAPGESLYAGMMRVLRTIFQPWETHPDIVKAYFRARA-APGGQRLVHRGL
MUL_0681|M.ulcerans_Agy99 PAPGECLYAGMMRVLRMIFQPWETHPDIVKAYFRARA-APGGQRLVHRGL
Mvan_3393|M.vanbaalenii_PYR-1 REPGETLHDALMRLFRVLFEPWERHPAMLAAYFRART-GPSGKRLLRRGL
Mflv_1903|M.gilvum_PYR-GCK -AAGLSLRQGLMSLFRTIFEPWERHPEMLKTYFRVRS-SPNGGKLFRFGF
MSMEG_5811|M.smegmatis_MC2_155 RTPGVSLYAALTGLLRTIFEPWERHPAMLEAYFRVRS-SRSGQKLFRFGF
MAV_3548|M.avium_104 ELPGKSMYSDLMHVMRTIFEPWERHPLMLRSYFQARS-GPGGKRLIQRGV
Mb1581|M.bovis_AF2122/97 ---TGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQF
Rv1556|M.tuberculosis_H37Rv ---TGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQF
MAB_3372|M.abscessus_ATCC_1997 AGLPDTIEDTVRVFVGSAIANHRDSPRLHRVLFEEAPRPPEFLAMLHRSE
TH_2255|M.thermoresistible__bu SGPQGDYYVEAFTLAILKFR---RHRVLHRMITDEPG--FILHLAQQHWG
. :
MMAR_0929|M.marinum_M DMVVPAAMEVLAGVDENFIHDLD---TVISSLVYGLLGRFTAGEIAITEI
MUL_0681|M.ulcerans_Agy99 DMVVPAAMEVLAGVEEDFIHDLD---TVISSLVYGLVGRFTAGEIAITEI
Mvan_3393|M.vanbaalenii_PYR-1 DVVVPAALDVLAGVDEEFIADMD---TVIANVIYGLLGRFAAGEITITDI
Mflv_1903|M.gilvum_PYR-GCK DIVAPAGMELLKGVDEEFVVSLE---AILANVIYGLLGRFSSGEIAVTEI
MSMEG_5811|M.smegmatis_MC2_155 DIVAPAGLELLADVDDEFVADLD---TIVSTVVYGLLGRFAAGEIAVTDI
MAV_3548|M.avium_104 EAVVPVAKSVLAQADPGFVNDLE---LILTGVVFGFLTRFAQGEIEVTEI
Mb1581|M.bovis_AF2122/97 VDHRKALIQYILQQAVDRGEISS---AAISDELWDLLPGYLIFRSIIPNR
Rv1556|M.tuberculosis_H37Rv VDHRKALIQYILQQAVDRGEISS---AAISDELWDLLPGYLIFRSIIPNR
MAB_3372|M.abscessus_ATCC_1997 DAVIAAAEAVLAAHPEVRVTETDTAARMVVATIESLVHRLIAGPRPIDP-
TH_2255|M.thermoresistible__bu AAVERMAEALRVIFPAGFAERIG---EAAVIEFADTILRYAAMALLLPSV
. . : :
MMAR_0929|M.marinum_M LPSIDRTVFWLIRGY---EAS---RRAG------------------
MUL_0681|M.ulcerans_Agy99 LPSIDRTVFWLIRGY---EAS---RRAG------------------
Mvan_3393|M.vanbaalenii_PYR-1 LPAIDRTVYRLTAGYA-LEAAGDGVRRG------------------
Mflv_1903|M.gilvum_PYR-GCK LPVLDRTVYWLTRGY---EAP-DSDSAEHFPTTPCAPTGR------
MSMEG_5811|M.smegmatis_MC2_155 VPILDRTVYWLTTGY---EAAGNARPGERRRRSPARRHRN------
MAV_3548|M.avium_104 VPGIERTVYWLTQAYQNADAGRQPHISGGGISQPSEGSTSSLYCGQ
Mb1581|M.bovis_AF2122/97 PPTQDTVQALVDDVI----LPSLTRSTG------------------
Rv1556|M.tuberculosis_H37Rv PPTQDTVQALVDDVI----LPSLTRSTG------------------
MAB_3372|M.abscessus_ATCC_1997 -QLFEDQLVDMLTRY----------LTG------------------
TH_2255|M.thermoresistible__bu QPLDTADDIRAFATRHFLPSLPAALHTGSA----------------