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MTARVGTQLASPETVTAPAVRRDDRILDIVVHLLQTEGYDAVQLREVARRARTSLATIYKRYANRDELIL AALEFWMDEHHYAGLAEQTPAPGECLYAGMMRVLRMIFQPWETHPDIVKAYFRARAAPGGQRLVHRGLDM VVPAAMEVLAGVEEDFIHDLDTVISSLVYGLVGRFTAGEIAITEILPSIDRTVFWLIRGYEASRRAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0681 | - | - | 100% (207) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4956 | - | 3e-09 | 33.33% (96) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_1934 | - | 4e-08 | 39.39% (66) | regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 1e-08 | 40.91% (66) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_1903 | - | 1e-61 | 58.82% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 1e-08 | 40.91% (66) | regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 5e-05 | 21.89% (201) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0579c | - | 2e-07 | 28.73% (181) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0929 | - | 1e-113 | 97.58% (207) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3548 | - | 3e-54 | 54.19% (179) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5811 | - | 5e-65 | 59.46% (185) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2255 | - | 9e-07 | 46.94% (49) | TetR-family protein transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3393 | - | 5e-67 | 66.29% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1581|M.bovis_AF2122/97 ------------------------MVGAVTQIADRPTDPSPWSPRETELL
Rv1556|M.tuberculosis_H37Rv ------------------------MVGAVTQIADRPTDPSPWSPRETELL
MUL_0681|M.ulcerans_Agy99 ---------------------MTARVGTQLASPETVTAPAVRRDDR--IL
MMAR_0929|M.marinum_M ---------------------MTARVGTQLASPETVTAPAVRRDDR--IL
Mvan_3393|M.vanbaalenii_PYR-1 ----------------------------------------MGAEDP--IL
Mflv_1903|M.gilvum_PYR-GCK -----------------------------------MDEGTAPHPDRDGLL
MSMEG_5811|M.smegmatis_MC2_155 -----------------------------------MGEDIEERDDR--LL
MAV_3548|M.avium_104 -------------------------------MTAKGPDAPIVSGDP--IL
MAB_0579c|M.abscessus_ATCC_199 MATPRTSSASEAAQSGDGDTDATSQPAAVSALSDDDLGSSAQRERRKRIL
TH_2255|M.thermoresistible__bu -------------------------------------MPERPDPARQAIL
MLBr_02568|M.leprae_Br4923 --------------------------------MAGGAKRIPRAVREQQML
:*
Mb1581|M.bovis_AF2122/97 AVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGI
Rv1556|M.tuberculosis_H37Rv AVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGI
MUL_0681|M.ulcerans_Agy99 DIVVHLLQTEGYDAVQLREVARRARTSLATIYKRYANRDELILAALEFWM
MMAR_0929|M.marinum_M DIVVHLLQTEGYDAVQLREVARRARTSLATIYKRYANRDELILAALEFWM
Mvan_3393|M.vanbaalenii_PYR-1 TVVVDLLENEGYDAVQLREVARRSRTSLTTIYKRYSNRDELILAALEAWT
Mflv_1903|M.gilvum_PYR-GCK DVVVDMLETDGYDAVQLRVVARRARSSLATIYKRYPTRDDLILAALEYWV
MSMEG_5811|M.smegmatis_MC2_155 DVVTEILETEGYEAVQLREVARRARTSLATIYKRFATRDDLILAALEYWM
MAV_3548|M.avium_104 GIVVDMLDTGGYEAVQLREVARRARVSMATIYKRYRTRDELIVAALEGWM
MAB_0579c|M.abscessus_ATCC_199 DATLAIASKGGYEAVQMRTVAERADVAVGTLYRYFPSKVHLLVSALEREF
TH_2255|M.thermoresistible__bu DAAVVEFEQHGFRKVALEDVARRAGVSRTTIYRRFTNRDELVAAVVDREN
MLBr_02568|M.leprae_Br4923 DAAVQMFSVNGYHKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREM
. . *: : :* : : :* : .: .*. : .
Mb1581|M.bovis_AF2122/97 RQVAVPPN---------TGNLRDDLLRLGELICREVGQHASTIRAVLVEV
Rv1556|M.tuberculosis_H37Rv RQVAVPPN---------TGNLRDDLLRLGELICREVGQHASTIRAVLVEV
MUL_0681|M.ulcerans_Agy99 DEHHYAGL--AEQTPAPGECLYAGMMRVLRMIFQPWETHPDIVKAYFRAR
MMAR_0929|M.marinum_M DEHHYAGL--AEQTPAPGESLYAGMMRVLRTIFQPWETHPDIVKAYFRAR
Mvan_3393|M.vanbaalenii_PYR-1 DTHRYAAV--AEQRREPGETLHDALMRLFRVLFEPWERHPAMLAAYFRAR
Mflv_1903|M.gilvum_PYR-GCK ARHRYAGI--AVPP-AAGLSLRQGLMSLFRTIFEPWERHPEMLKTYFRVR
MSMEG_5811|M.smegmatis_MC2_155 QKNRYSGV--TPRRRTPGVSLYAALTGLLRTIFEPWERHPAMLEAYFRVR
MAV_3548|M.avium_104 DANRYARLP-SLIDELPGKSMYSDLMHVMRTIFEPWERHPLMLRSYFQAR
MAB_0579c|M.abscessus_ATCC_199 EQIDAKSDRNAVSGGTPYERLHAAITRLNRNMQRNPLLTEAMTRALVFAD
TH_2255|M.thermoresistible__bu -AALFADIAAELKHSGPQGDYYVEAFTLAILKFR---RHRVLHRMITDEP
MLBr_02568|M.leprae_Br4923 SRFIAMVRADIDFTQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLP
.
Mb1581|M.bovis_AF2122/97 SRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISSA-AISDELWDLLP
Rv1556|M.tuberculosis_H37Rv SRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISSA-AISDELWDLLP
MUL_0681|M.ulcerans_Agy99 A-APGGQRLVHRGLDMVVPAAMEVLAGVEEDFIHDLDT-VISSLVYGLVG
MMAR_0929|M.marinum_M A-APGGQRLVHRGLDMVVPAAMEVLAGVDENFIHDLDT-VISSLVYGLLG
Mvan_3393|M.vanbaalenii_PYR-1 T-GPSGKRLLRRGLDVVVPAALDVLAGVDEEFIADMDT-VIANVIYGLLG
Mflv_1903|M.gilvum_PYR-GCK S-SPNGGKLFRFGFDIVAPAGMELLKGVDEEFVVSLEA-ILANVIYGLLG
MSMEG_5811|M.smegmatis_MC2_155 S-SRSGQKLFRFGFDIVAPAGLELLADVDDEFVADLDT-IVSTVVYGLLG
MAV_3548|M.avium_104 S-GPGGKRLIQRGVEAVVPVAKSVLAQADPGFVNDLEL-ILTGVVFGFLT
MAB_0579c|M.abscessus_ATCC_199 ASAAGEVDHVGRLMDGIFARAMAG-EDDPTDAQFHIAR-VISDVWTSNMI
TH_2255|M.thermoresistible__bu G--FILHLAQQHWGAAVERMAEALRVIFPAGFAERIGE-AAVIEFADTIL
MLBr_02568|M.leprae_Br4923 AFAQTVREARDQITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMAT
Mb1581|M.bovis_AF2122/97 GYLIFRSIIPNRPP--TQDTVQALVDDVI----LPSLTRSTG--------
Rv1556|M.tuberculosis_H37Rv GYLIFRSIIPNRPP--TQDTVQALVDDVI----LPSLTRSTG--------
MUL_0681|M.ulcerans_Agy99 RFTAGEIAITEILP--SIDRTVFWLIRGY---EAS---RRAG--------
MMAR_0929|M.marinum_M RFTAGEIAITEILP--SIDRTVFWLIRGY---EAS---RRAG--------
Mvan_3393|M.vanbaalenii_PYR-1 RFAAGEITITDILP--AIDRTVYRLTAGYA-LEAAGDGVRRG--------
Mflv_1903|M.gilvum_PYR-GCK RFSSGEIAVTEILP--VLDRTVYWLTRGY---EAP-DSDSAEHFPTTPCA
MSMEG_5811|M.smegmatis_MC2_155 RFAAGEIAVTDIVP--ILDRTVYWLTTGY---EAAGNARPGERRRRSPAR
MAV_3548|M.avium_104 RFAQGEIEVTEIVP--GIERTVYWLTQAYQNADAGRQPHISGGGISQPSE
MAB_0579c|M.abscessus_ATCC_199 AWLTRRASATDVSH--RLDRTVRLLLGIT---------------------
TH_2255|M.thermoresistible__bu RYAAMALLLPSVQPLDTADDIRAFATRHFLPSLPAALHTGSA--------
MLBr_02568|M.leprae_Br4923 RLTTGDIAVDEAAE--LMINLFWHGLKGAPADRDFGPSIVAG--------
.
Mb1581|M.bovis_AF2122/97 ----------
Rv1556|M.tuberculosis_H37Rv ----------
MUL_0681|M.ulcerans_Agy99 ----------
MMAR_0929|M.marinum_M ----------
Mvan_3393|M.vanbaalenii_PYR-1 ----------
Mflv_1903|M.gilvum_PYR-GCK PTGR------
MSMEG_5811|M.smegmatis_MC2_155 RHRN------
MAV_3548|M.avium_104 GSTSSLYCGQ
MAB_0579c|M.abscessus_ATCC_199 ----------
TH_2255|M.thermoresistible__bu ----------
MLBr_02568|M.leprae_Br4923 ----------