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TAKGPDAPIVSGDPILGIVVDMLDTGGYEAVQLREVARRARVSMATIYKRYRTRDELIVAALEGWMDANR YARLPSLIDELPGKSMYSDLMHVMRTIFEPWERHPLMLRSYFQARSGPGGKRLIQRGVEAVVPVAKSVLA QADPGFVNDLELILTGVVFGFLTRFAQGEIEVTEIVPGIERTVYWLTQAYQNADAGRQPHISGGGISQPS EGSTSSLYCGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3548 | - | - | 100% (222) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0584 | - | 7e-07 | 29.41% (102) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3803 | - | 6e-06 | 24.65% (142) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 1e-06 | 28.43% (102) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1903 | - | 4e-52 | 52.58% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 1e-06 | 28.43% (102) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_00316 | - | 4e-05 | 23.50% (200) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0579c | - | 7e-07 | 24.86% (181) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0929 | - | 3e-56 | 56.42% (179) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5811 | - | 2e-52 | 54.59% (185) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1745 | - | 2e-07 | 30.39% (102) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. ulcerans Agy99 | MUL_0681 | - | 3e-54 | 54.19% (179) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3393 | - | 5e-56 | 55.43% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1903|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5811|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0929|M.marinum_M --------------------------------------MTARVGTQLASP
MUL_0681|M.ulcerans_Agy99 --------------------------------------MTARVGTQLASP
Mvan_3393|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3548|M.avium_104 ------------------------------------------------MT
Mb3605|M.bovis_AF2122/97 ---------------------------------------------MAVLA
Rv3574|M.tuberculosis_H37Rv ---------------------------------------------MAVLA
TH_1745|M.thermoresistible__bu MSSSTGTNPGRGSDSTGSETNGAAATGAGSGSTGTSRTRGRQVTNVAVLT
MAB_0579c|M.abscessus_ATCC_199 -------------MATPRTSSASEAAQSGDGDTDATS----QPAAVSALS
MLBr_00316|M.leprae_Br4923 ------------------------------------MSVPRSGLSVQMAQ
Mflv_1903|M.gilvum_PYR-GCK --MDEGTAPHPDRDGLLDVVVDMLETDGYDAVQLRVVARRARSSLATIYK
MSMEG_5811|M.smegmatis_MC2_155 --MGEDIEERDDR--LLDVVTEILETEGYEAVQLREVARRARTSLATIYK
MMAR_0929|M.marinum_M ETVTAPAVRRDDR--ILDIVVHLLQTEGYDAVQLREVARRARTSLATIYK
MUL_0681|M.ulcerans_Agy99 ETVTAPAVRRDDR--ILDIVVHLLQTEGYDAVQLREVARRARTSLATIYK
Mvan_3393|M.vanbaalenii_PYR-1 -------MGAEDP--ILTVVVDLLENEGYDAVQLREVARRSRTSLTTIYK
MAV_3548|M.avium_104 AKGPDAPIVSGDP--ILGIVVDMLDTGGYEAVQLREVARRARVSMATIYK
Mb3605|M.bovis_AF2122/97 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
Rv3574|M.tuberculosis_H37Rv ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
TH_1745|M.thermoresistible__bu DSELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MAB_0579c|M.abscessus_ATCC_199 DDDLGSSAQRERRKRILDATLAIASKGGYEAVQMRTVAERADVAVGTLYR
MLBr_00316|M.leprae_Br4923 PARPLRADAARNRARILGVAYEAFATEG-LSVPIDEIARRAGVGAGTVYR
:* . . * :* : :* *: . *:*:
Mflv_1903|M.gilvum_PYR-GCK RYPTRDDLILAALEYWVARHRYAGI--AVPP-AAGLSLRQGLMSLFRTIF
MSMEG_5811|M.smegmatis_MC2_155 RFATRDDLILAALEYWMQKNRYSGV--TPRRRTPGVSLYAALTGLLRTIF
MMAR_0929|M.marinum_M RYANRDELILAALEFWMDEHHYAGL--AEQTPAPGESLYAGMMRVLRTIF
MUL_0681|M.ulcerans_Agy99 RYANRDELILAALEFWMDEHHYAGL--AEQTPAPGECLYAGMMRVLRMIF
Mvan_3393|M.vanbaalenii_PYR-1 RYSNRDELILAALEAWTDTHRYAAV--AEQRREPGETLHDALMRLFRVLF
MAV_3548|M.avium_104 RYRTRDELIVAALEGWMDANRYARLP-SLIDELPGKSMYSDLMHVMRTIF
Mb3605|M.bovis_AF2122/97 YFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQ
Rv3574|M.tuberculosis_H37Rv YFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQ
TH_1745|M.thermoresistible__bu YFPSKVHLLVSALGREFERIDAKTDRSTLVGDTPYERLNFMVSRLNRAMQ
MAB_0579c|M.abscessus_ATCC_199 YFPSKVHLLVSALEREFEQIDAKSDRNAVSGGTPYERLHAAITRLNRNMQ
MLBr_00316|M.leprae_Br4923 HFPTKEALCAAVIGDRMPHLVDDGY-VLLKSAGPGE----ALFTYLRSLV
: .: * :.: . : * :
Mflv_1903|M.gilvum_PYR-GCK EPWERHPEMLKTYFRVRSSPNGGKLFRFGFDIVAPAGMELLKGVDEEFVV
MSMEG_5811|M.smegmatis_MC2_155 EPWERHPAMLEAYFRVRSSRSGQKLFRFGFDIVAPAGLELLADVDDEFVA
MMAR_0929|M.marinum_M QPWETHPDIVKAYFRARAAPGGQRLVHRGLDMVVPAAMEVLAGVDENFIH
MUL_0681|M.ulcerans_Agy99 QPWETHPDIVKAYFRARAAPGGQRLVHRGLDMVVPAAMEVLAGVEEDFIH
Mvan_3393|M.vanbaalenii_PYR-1 EPWERHPAMLAAYFRARTGPSGKRLLRRGLDVVVPAALDVLAGVDEEFIA
MAV_3548|M.avium_104 EPWERHPLMLRSYFQARSGPGGKRLIQRGVEAVVPVAKSVLAQADPGFVN
Mb3605|M.bovis_AF2122/97 RNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAN-GEPTEDQY
Rv3574|M.tuberculosis_H37Rv RNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAN-GEPTEDQY
TH_1745|M.thermoresistible__bu RNPLLTEAMTRAFVFADASAAGEVDHVGRLMDSMFARAMAD-GEPTEDQY
MAB_0579c|M.abscessus_ATCC_199 RNPLLTEAMTRALVFADASAAGEVDHVGRLMDGIFARAMAGEDDPTDAQF
MLBr_00316|M.leprae_Br4923 LHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLTILSDLLYAAQYAGTA
. .
Mflv_1903|M.gilvum_PYR-GCK SLEAILANVIYGLLGRFSSGEIAVTEILPVLDRTVYWLTRGY---EAP-D
MSMEG_5811|M.smegmatis_MC2_155 DLDTIVSTVVYGLLGRFAAGEIAVTDIVPILDRTVYWLTTGY---EAAGN
MMAR_0929|M.marinum_M DLDTVISSLVYGLLGRFTAGEIAITEILPSIDRTVFWLIRGY---EAS--
MUL_0681|M.ulcerans_Agy99 DLDTVISSLVYGLVGRFTAGEIAITEILPSIDRTVFWLIRGY---EAS--
Mvan_3393|M.vanbaalenii_PYR-1 DMDTVIANVIYGLLGRFAAGEITITDILPAIDRTVYRLTAGYA-LEAAGD
MAV_3548|M.avium_104 DLELILTGVVFGFLTRFAQGEIEVTEIVPGIERTVYWLTQAYQNADAGRQ
Mb3605|M.bovis_AF2122/97 HIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQ---DSA--
Rv3574|M.tuberculosis_H37Rv HIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQ---DSA--
TH_1745|M.thermoresistible__bu HIARVISDVWLSNLLAWLTRRASATDVSKRLELAVRLLVGDG---KNPKV
MAB_0579c|M.abscessus_ATCC_199 HIARVISDVWTSNMIAWLTRRASATDVSHRLDRTVRLLLGIT--------
MLBr_00316|M.leprae_Br4923 RTDVGVREVKSILVGCQAMEAYNSALAERVTDVVVDGLRAAR--------
: : : : : .* *
Mflv_1903|M.gilvum_PYR-GCK SDSAEHFPTTPCAPTGR------
MSMEG_5811|M.smegmatis_MC2_155 ARPGERRRRSPARRHRN------
MMAR_0929|M.marinum_M -RRAG------------------
MUL_0681|M.ulcerans_Agy99 -RRAG------------------
Mvan_3393|M.vanbaalenii_PYR-1 GVRRG------------------
MAV_3548|M.avium_104 PHISGGGISQPSEGSTSSLYCGQ
Mb3605|M.bovis_AF2122/97 -----------------------
Rv3574|M.tuberculosis_H37Rv -----------------------
TH_1745|M.thermoresistible__bu -----------------------
MAB_0579c|M.abscessus_ATCC_199 -----------------------
MLBr_00316|M.leprae_Br4923 -----------------------