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GEDIEERDDRLLDVVTEILETEGYEAVQLREVARRARTSLATIYKRFATRDDLILAALEYWMQKNRYSGV TPRRRTPGVSLYAALTGLLRTIFEPWERHPAMLEAYFRVRSSRSGQKLFRFGFDIVAPAGLELLADVDDE FVADLDTIVSTVVYGLLGRFAAGEIAVTDIVPILDRTVYWLTTGYEAAGNARPGERRRRSPARRHRN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5811 | - | - | 100% (208) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6042 | - | 7e-09 | 33.01% (103) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 2e-06 | 48.98% (49) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 6e-09 | 32.04% (103) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1903 | - | 8e-69 | 69.83% (179) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 6e-09 | 32.04% (103) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_00815 | - | 2e-05 | 24.31% (181) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0579c | - | 9e-11 | 31.91% (188) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0929 | - | 7e-67 | 61.62% (185) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3548 | - | 2e-52 | 54.59% (185) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1745 | - | 4e-09 | 33.01% (103) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. ulcerans Agy99 | MUL_0681 | - | 3e-65 | 59.46% (185) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3393 | - | 6e-65 | 62.70% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5811|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1903|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_0929|M.marinum_M --------------------------------------MTARVGTQLASP
MUL_0681|M.ulcerans_Agy99 --------------------------------------MTARVGTQLASP
Mvan_3393|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3548|M.avium_104 ------------------------------------------------MT
Mb3605|M.bovis_AF2122/97 ---------------------------------------------MAVLA
Rv3574|M.tuberculosis_H37Rv ---------------------------------------------MAVLA
TH_1745|M.thermoresistible__bu MSSSTGTNPGRGSDSTGSETNGAAATGAGSGSTGTSRTRGRQVTNVAVLT
MAB_0579c|M.abscessus_ATCC_199 -------------MATPRTSSASEAAQSGDGDTDATS----QPAAVSALS
MLBr_00815|M.leprae_Br4923 ----------------------MNNLAKAAQRRTVRPIDRGRLSDDIATP
MSMEG_5811|M.smegmatis_MC2_155 --MGEDIEERDDR--LLDVVTEILETEGYEAVQLREVARRARTSLATIYK
Mflv_1903|M.gilvum_PYR-GCK --MDEGTAPHPDRDGLLDVVVDMLETDGYDAVQLRVVARRARSSLATIYK
MMAR_0929|M.marinum_M ETVTAPAVRRDDR--ILDIVVHLLQTEGYDAVQLREVARRARTSLATIYK
MUL_0681|M.ulcerans_Agy99 ETVTAPAVRRDDR--ILDIVVHLLQTEGYDAVQLREVARRARTSLATIYK
Mvan_3393|M.vanbaalenii_PYR-1 -------MGAEDP--ILTVVVDLLENEGYDAVQLREVARRSRTSLTTIYK
MAV_3548|M.avium_104 AKGPDAPIVSGDP--ILGIVVDMLDTGGYEAVQLREVARRARVSMATIYK
Mb3605|M.bovis_AF2122/97 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
Rv3574|M.tuberculosis_H37Rv ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
TH_1745|M.thermoresistible__bu DSELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MAB_0579c|M.abscessus_ATCC_199 DDDLGSSAQRERRKRILDATLAIASKGGYEAVQMRTVAERADVAVGTLYR
MLBr_00815|M.leprae_Br4923 NQRSNRLSRDKRRGQLLIVASDVFVDHGYHAAGMDEIADRAGVSKPVLYQ
:* . : **.*. : :* *: : .:*:
MSMEG_5811|M.smegmatis_MC2_155 RFATRDDLILAALEYWMQKNRYSGV-TPRRRTPGVS-LYAALTGLLRTIF
Mflv_1903|M.gilvum_PYR-GCK RYPTRDDLILAALEYWVARHRYAGI-AVPP-AAGLS-LRQGLMSLFRTIF
MMAR_0929|M.marinum_M RYANRDELILAALEFWMDEHHYAGL-AEQTPAPGES-LYAGMMRVLRTIF
MUL_0681|M.ulcerans_Agy99 RYANRDELILAALEFWMDEHHYAGL-AEQTPAPGEC-LYAGMMRVLRMIF
Mvan_3393|M.vanbaalenii_PYR-1 RYSNRDELILAALEAWTDTHRYAAV-AEQRREPGET-LHDALMRLFRVLF
MAV_3548|M.avium_104 RYRTRDELIVAALEGWMDANRYARLPSLIDELPGKS-MYSDLMHVMRTIF
Mb3605|M.bovis_AF2122/97 YFPSKVHLLVSALGREFSRIDAKTD---RSAVAGAT-PFQRLNFMVGKLN
Rv3574|M.tuberculosis_H37Rv YFPSKVHLLVSALGREFSRIDAKTD---RSAVAGAT-PFQRLNFMVGKLN
TH_1745|M.thermoresistible__bu YFPSKVHLLVSALGREFERIDAKTD---RSTLVGDT-PYERLNFMVSRLN
MAB_0579c|M.abscessus_ATCC_199 YFPSKVHLLVSALEREFEQIDAKSD---RNAVSGGT-PYERLHAAITRLN
MLBr_00815|M.leprae_Br4923 HFSSKLELYLAVLERHMNNLVSSVQQALRTTTNNRQRLHAAVQAFFDFIE
: .: .* ::.* . : . :
MSMEG_5811|M.smegmatis_MC2_155 EPWERHPAMLEAY-----FRVRSSRSGQKLFRFGFDIVAPAGLELLADVD
Mflv_1903|M.gilvum_PYR-GCK EPWERHPEMLKTY-----FRVRSSPNGGKLFRFGFDIVAPAGMELLKGVD
MMAR_0929|M.marinum_M QPWETHPDIVKAY-----FRARAAPGGQRLVHRGLDMVVPAAMEVLAGVD
MUL_0681|M.ulcerans_Agy99 QPWETHPDIVKAY-----FRARAAPGGQRLVHRGLDMVVPAAMEVLAGVE
Mvan_3393|M.vanbaalenii_PYR-1 EPWERHPAMLAAY-----FRARTGPSGKRLLRRGLDVVVPAALDVLAGVD
MAV_3548|M.avium_104 EPWERHPLMLRSY-----FQARSGPGGKRLIQRGVEAVVPVAKSVLAQAD
Mb3605|M.bovis_AF2122/97 RAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAN-GEPT
Rv3574|M.tuberculosis_H37Rv RAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMAN-GEPT
TH_1745|M.thermoresistible__bu RAMQRNPLLTEAMTRAFVFADASAAGEVDHVGRLMDSMFARAMAD-GEPT
MAB_0579c|M.abscessus_ATCC_199 RNMQRNPLLTEAMTRALVFADASAAGEVDHVGRLMDGIFARAMAGEDDPT
MLBr_00815|M.leprae_Br4923 HDGQGYRLIFENDN----ITEPRVAAQVRVATESCIDAVFALISADSRLD
. : : :
MSMEG_5811|M.smegmatis_MC2_155 DEFVADLDTIVSTVVYGLLGRFAAGEIAVTDIVPILDRTVYWLTTGY---
Mflv_1903|M.gilvum_PYR-GCK EEFVVSLEAILANVIYGLLGRFSSGEIAVTEILPVLDRTVYWLTRGY---
MMAR_0929|M.marinum_M ENFIHDLDTVISSLVYGLLGRFTAGEIAITEILPSIDRTVFWLIRGY---
MUL_0681|M.ulcerans_Agy99 EDFIHDLDTVISSLVYGLVGRFTAGEIAITEILPSIDRTVFWLIRGY---
Mvan_3393|M.vanbaalenii_PYR-1 EEFIADMDTVIANVIYGLLGRFAAGEITITDILPAIDRTVYRLTAGYA-L
MAV_3548|M.avium_104 PGFVNDLELILTGVVFGFLTRFAQGEIEVTEIVPGIERTVYWLTQAYQNA
Mb3605|M.bovis_AF2122/97 EDQYH-IARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQ---
Rv3574|M.tuberculosis_H37Rv EDQYH-IARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQ---
TH_1745|M.thermoresistible__bu EDQYH-IARVISDVWLSNLLAWLTRRASATDVSKRLELAVRLLVGDG---
MAB_0579c|M.abscessus_ATCC_199 DAQFH-IARVISDVWTSNMIAWLTRRASATDVSHRLDRTVRLLLGIT---
MLBr_00815|M.leprae_Br4923 PHRARMVAVGLVGISVDCARYWLDTNRPISKS-DAVEGTVQFAWGGLSHV
: : : . : . :. :: :*
MSMEG_5811|M.smegmatis_MC2_155 EAAGNARPGERRRRSPARRHRN------
Mflv_1903|M.gilvum_PYR-GCK EAP-DSDSAEHFPTTPCAPTGR------
MMAR_0929|M.marinum_M EAS---RRAG------------------
MUL_0681|M.ulcerans_Agy99 EAS---RRAG------------------
Mvan_3393|M.vanbaalenii_PYR-1 EAAGDGVRRG------------------
MAV_3548|M.avium_104 DAGRQPHISGGGISQPSEGSTSSLYCGQ
Mb3605|M.bovis_AF2122/97 DSA-------------------------
Rv3574|M.tuberculosis_H37Rv DSA-------------------------
TH_1745|M.thermoresistible__bu KNPKV-----------------------
MAB_0579c|M.abscessus_ATCC_199 ----------------------------
MLBr_00815|M.leprae_Br4923 PLTRL-----------------------