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VNHTVDVPAEPSSFPLVAGRTALIVIDMQRDFLLPGGFGESLGNDVGRLLKVVPPLASLIAAARAAGVMV VHTREGHQPDLSDCPPAKLNRGTPSKRIGDPGRYGRILIRGEYGHDIIDELAPIDGEIVIDKPGKGAFYA TSLSDVLTEAGITQLLITGVTTEVCVHTTTREANDRGYQCLVVSDCVGSYFPEFQRVGLEMIKAQGGIFG WVADTSSVIPALARLSSIPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3053 | - | - | 100% (230) | isochorismatase hydrolase |
| M. vanbaalenii PYR-1 | Mvan_4942 | - | 2e-13 | 32.12% (165) | isochorismatase hydrolase |
| M. vanbaalenii PYR-1 | Mvan_1859 | - | 3e-10 | 27.81% (187) | isochorismatase hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2275 | - | 1e-10 | 30.59% (170) | isochorismatase hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3431c | - | 5e-55 | 49.30% (213) | isochorismatase hydrolase |
| M. marinum M | MMAR_2657 | - | 1e-43 | 47.03% (185) | isochorismatase family protein |
| M. avium 104 | MAV_5193 | - | 5e-11 | 26.49% (185) | isochorismatase family protein |
| M. smegmatis MC2 155 | MSMEG_4379 | - | 7e-16 | 29.86% (221) | isochorismatase hydrolase |
| M. thermoresistible (build 8) | TH_0553 | - | 1e-09 | 26.55% (177) | isochorismatase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3431c|M.abscessus_ATCC_199 ---------------------------MTGQVDAQPYPWPFDGPVDPGRT
MMAR_2657|M.marinum_M --------------------------------------------------
Mvan_3053|M.vanbaalenii_PYR-1 ---------------------------MNHTVDVPAEPSSFP--LVAGRT
MSMEG_4379|M.smegmatis_MC2_155 ------------------------------MVTDQSAAMSFT----AGTT
Mflv_2275|M.gilvum_PYR-GCK ---------------------------MSDPQTLRALAGLPLTPMSLADS
MAV_5193|M.avium_104 MLSADHRFQQTMTVRFGRRGRVPITGWVQSRRGVGMAGEDHYTRPCADSA
TH_0553|M.thermoresistible__bu -------------------------------MFILMPQPRLSDLIDPRST
MAB_3431c|M.abscessus_ATCC_199 AVLCIDWQVDFCGRGGYVDTMGYDLSLTRAGLEPTARVLAAARAVGMTII
MMAR_2657|M.marinum_M --------------------MGYDLSLVRAPLGPAQTVLEAARKLGLLIV
Mvan_3053|M.vanbaalenii_PYR-1 ALIVIDMQRDFLLPGGFGESLGNDVGRLLKVVPPLASLIAAARAAGVMVV
MSMEG_4379|M.smegmatis_MC2_155 GLVVIDPYNDFISEGGKVWDLLRGVAEAIGCVPHMIEMTEAARASGIPVF
Mflv_2275|M.gilvum_PYR-GCK ALVLIDCQNTYTRG-------VMELDGVQAALDEAATLLDRARTAGIAVV
MAV_5193|M.avium_104 ALVLIDVQRDFYAD-----DAPMRVEGTSAALGAMAELARAFRRRELPIV
TH_0553|M.thermoresistible__bu ALVTQECQGGVIGPQAG--LPHLAAEAQREAIPNIGKLLDAARSAGVTVV
: : * : :.
MAB_3431c|M.abscessus_ATCC_199 HTREG-HRPDLSDLPANKRWRSARIGAEIGVAGPCGRILVKGEPGWEIVP
MMAR_2657|M.marinum_M HTREG-HRPDLSDLPANKRWRSARIGAEIGVAGPCGRVLTRGEPGWEIIP
Mvan_3053|M.vanbaalenii_PYR-1 HTREG-HQPDLSDCPPAKLNRGTPS-KRIGDPGRYGRILIRGEYGHDIID
MSMEG_4379|M.smegmatis_MC2_155 YALHRRYRPGD--------YESWRYVAPIQRAAWSRRTFEYGSWGGEIHP
Mflv_2275|M.gilvum_PYR-GCK HIQHD--------------------------DGPGSLYDIEGESG-AIVD
MAV_5193|M.avium_104 HVVRLYRADG-----------SNADPVRRRFIEDGARVAEPGSPGSQIAP
TH_0553|M.thermoresistible__bu HCLIQRRPDGR---------GSNTNARLFAAATSFDADLTPGTPGASVLP
: * * :
MAB_3431c|M.abscessus_ATCC_199 EVAPL------------------PGEPIIDKPGKGA-FYATDLDLVLRTR
MMAR_2657|M.marinum_M EMEPL------------------PGEMVVDKLGKGS-FYATDLELILTTR
Mvan_3053|M.vanbaalenii_PYR-1 ELAPI------------------DGEIVIDKPGKGA-FYATSLSDVLTEA
MSMEG_4379|M.smegmatis_MC2_155 DLAPR------------------PGDIVAQEHWCSSGFANTDLDMLLKRH
Mflv_2275|M.gilvum_PYR-GCK RVAPR------------------DGERVVVKNYPNS-FVQTDLDDVLKSY
MAV_5193|M.avium_104 ELLPKAVELDHQLLLSGGFQQIGPAEHVMYKPRWGA-FYGTKLEQHLRES
TH_0553|M.thermoresistible__bu EFGPE------------------PEDLVLTRMHGVGPMTGTDLDSVLRNL
. * : : . . : *.*. *
MAB_3431c|M.abscessus_ATCC_199 GIRYIVLTGITTDVCVHTTMREANDRGFECLILSDCTGATDAGNHAAALK
MMAR_2657|M.marinum_M RITHLIFTGIATDVCVHTTMREANDRGYECLLLSDCTGATDYANHLAALK
Mvan_3053|M.vanbaalenii_PYR-1 GITQLLITGVTTEVCVHTTTREANDRGYQCLVVSDCVGSYFPEFQRVGLE
MSMEG_4379|M.smegmatis_MC2_155 GIHQIIVVGLIAHTCVEATVRYGAELGYQVTLVRDATADYSVEEMRAALE
Mflv_2275|M.gilvum_PYR-GCK GASNLVLAGFMTHMCVNSTARGAFNLGYAPTVVAAATATRALPGVDG--D
MAV_5193|M.avium_104 GTDTLVFAGCNFPNCPRTSIYEASERDFRIVLVTDAISG----LYDRGAQ
TH_0553|M.thermoresistible__bu GIETIVGVGVSVNIAIPNFVMDAVNRGYRFVLPRDAVAGYPREYAEAVID
:: .* . . : .: : . . .
MAB_3431c|M.abscessus_ATCC_199 MVTMQGGVFGAVADSNQLLGAL----------
MMAR_2657|M.marinum_M MITMQGGVFGAHATNGALLEAFN-KVRDRRG-
Mvan_3053|M.vanbaalenii_PYR-1 MIKAQGGIFGWVADTSSVIPALA-RLSSIPA-
MSMEG_4379|M.smegmatis_MC2_155 VTLPN--YASAIASTDEVIHAIA-GMR-----
Mflv_2275|M.gilvum_PYR-GCK TVAASAVHAASLAAVADLFAVVVPGEKDIPG-
MAV_5193|M.avium_104 ECRAIGVAVRDTAQTLDWLGG-----------
TH_0553|M.thermoresistible__bu NSLALLATVTSTDEVTGVWNGATDRRLDVDTR